Clinical Neuroepidemiology of Acute and Chronic Disorders
- 1st Edition - May 15, 2023
- Latest edition
- Authors: Jahangir Moini, Amparo Gutierrez, Nicholas Avgeropoulos
- Language: English
Clinical Neuroepidemiology of Acute and Chronic Disorders explores the epidemiology of disorders that affect the nervous system, providing comprehensive discussions on incide… Read more
Clinical Neuroepidemiology of Acute and Chronic Disorders explores the epidemiology of disorders that affect the nervous system, providing comprehensive discussions on incidence, prevalence, and more. With thorough coverage of a variety of disorders, chapters detail etiology, risk factors, pathophysiology, clinical manifestations, diagnosis, global incidence and prevalence, age-specific incidence, global mortality, prevention, treatment and prognosis for each disorder. Chapters uniquely discuss the effects of the COVID-19 coronavirus upon the nervous system and in relation to several diseases, including new discoveries and treatments for Alzheimer’s disease and migraine headaches. Real-world case studies with critical thinking questions and "Focus On" boxes highlight important information.
- Covers a variety of disorders and their etiology, including risk factors, pathophysiology clinical manifestations diagnosis, incidence of mortality, prevention, treatment and prognosis
- Features real-world case studies with critical thinking questions and answers
- Includes Focus On boxes that highlight key information in each chapter
- Highlights treatments for various disorders, including Alzheimer's disease and migraines
- Discusses the effects of COVID-19 on the nervous system in relation to several diseases
Neuroscientists, neuroepidemiologists graduate and undergraduate students in biological and biomedical sciences, post-doctoral fellows, researchers, neurologists, parasitologists, clinicians
Part I: Introduction
: Prevalence and Incidence in Neuroepidemiology
World Population
Aging of the Population
Life Expectancy
Distribution of Neurological Disorders by Gender and Age
Prevalence of Neurological Disorders
Incidence of Neurological Disorders
Global Epidemiology of Neurological Disorders
Global Death Rates from Neurological Disorders
Disability-adjusted Life Years for Neurological Disorders
Burden of Neurological Disorders
2: Neurologic Examination
History
Assessing Mental Conditions
Assessing the Cranial Nerves
Assessing Sensation
Assessing the Motor System
Assessing Muscle Strength
Assessing Coordination, Position, Pain, and Gait
Assessing Reflexes
Assessing the Autonomic Nervous System
Cerebrovascular Examination
3: Neurologic Tests and Procedures
Magnetic Resonance Imaging
Computed Tomography in Neurologic Disorders
Duplex Doppler Ultrasonography
Echoencephalography
Electroencephalography
Electromyography
Cerebral Catheter Angiography
Lumbar Puncture
Nerve and Muscle Biopsy
4: Neurotransmission
Major Neurotransmitters
Acetylcholine
Glutamate and Aspartate
GABA
Serotonin
Dopamine
Norepinephrine
Endorphins and Enkephalins
Part II: Neurologic Disorders
5: Pain
Development of Pain
Acute Pain
Chronic Pain
Neuropathic Pain
Complex Regional Pain Syndrome
6: Meningitis
Types of Meningitis
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Meningitis
Prevention
Treatment
Prognosis
7: Brain Infections
Encephalitis
Brain Abscesses
Helminthic Brain Infections
Rabies
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Brain Infections
Prevention
Treatment
Prognosis
8: Headache
Cluster Headache
Migraine
Post-lumbar Puncture Headache
Tension Headache
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Headache
Prevention
Treatment
Prognosis
9: Function and Dysfunction of the Cerebral Lobes
Agnosia
Amnesias
Transient Global Amnesia
Aphasia
Apraxia
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Cerebral Lobe Dysfunction
Prevention
Treatment
Prognosis
10: Stroke
Ischemic Stroke
Transient Ischemic Attack
Intracerebral Hemorrhage
Subarachnoid Hemorrhage
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Stroke
Prevention
Treatment
Prognosis
11: Seizure Disorders
Types of Seizures
Generalized Seizures
Partial Seizures
Status Epilepticus
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Seizure Disorders
Suicide and Epilepsy
Prevention
Treatment
Prognosis
12: Delirium and Dementia
Delirium
Alzheimer’s Disease
Vascular Dementia
Lewy Body Dementia
Parkinson’s Disease Dementia
Frontotemporal Dementia
HIV-associated Dementia
Chronic Traumatic Encephalopathy
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Delirium and Dementia
Prevention
Treatment
Prognosis
13: Movement and Cerebellar Disorders
Chorea and Athetosis
Dystonias
Ataxia Syndrome
Huntington’s Disease
Myoclonus
Parkinson’s Disease
Tremor
Cerebellar Disorders
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Movement and Cerebellar Disorders
Prevention
Treatment
Prognosis
14: Demyelinating Disorders
Multiple Sclerosis
Neuromyelitis Optica
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Demyelinating Disorders
Prevention
Treatment
Prognosis
15: Autonomic Nervous System Disorders
Autonomic Neuropathies
Horner Syndrome
Multiple System Atrophy
Pure Autonomic Failure
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Autonomic Nervous System Disorders
Prevention
Treatment
Prognosis
16: Motor Unit and Peripheral Nervous System Disorders
Motor Unit Disorders
Myasthenia Gravis
Amyotrophic Lateral Sclerosis
Isaac’s Syndrome
Guillain-Barré Syndrome
Stiff-person Syndrome
Chronic Inflammatory Demyelinating Polyneuropathy
Hereditary Neuropathies
Nerve Root Disorders
Peripheral Neuropathy
Mononeuropathies
Multiple Mononeuropathy
Polyneuropathy
Spinal Muscular Atrophies
Thoracic Outlet Compression Syndromes
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Motor Unit and Peripheral Nervous System
Disorders
Prevention
Treatment
Prognosis
17: Prion Diseases
Creutzfeldt-Jakob Disease
Fatal Insomnia
Kuru
Gerstmann-Sträussler-Scheinker Disease
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Prion Diseases
Prevention
Treatment
Prognosis
18: Spinal Cord Disorders
Cervical Spondylosis
Spinal Cord Compression
Spinal Cord Infarction
Spinal Epidural Abscess
Spinal Subdural and Epidural Hematoma
Hereditary Spastic Paraparesis
Syrinx of the Spinal Cord
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Spinal Cord Disorders
Prevention
Treatment
Prognosis
19: Neuro-ophthalmologic and Cranial Nerve Disorders
Conjugate Gaze Palsies
Internuclear Ophthalmoplegia
Third Cranial Nerve Disorders
Fourth Cranial Nerve Disorders
Sixth Cranial Nerve Disorders
Trigeminal Neuralgia
Hemifacial Spasm
Glossopharyngeal Neuralgia
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Neuro-ophthalmologic and Cranial Nerve
Disorders
Prevention
Treatment
Prognosis
20: Brain and Spinal Tumors
Classifications of Brain Tumors
Meningioma
Glioma
Acoustic Neuroma
Pituitary Tumors
Primary Lymphoma of the Brain
Brain Tumors in Children
Spinal Cord Tumors
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Brain and Spinal Tumors
Prevention
Treatment
Prognosis
21: Sleep and Wakefulness Disorders
Circadian Rhythm Sleep Disorders
Snoring
Insomnia and Excessive Daytime Sleepiness
Narcolepsy
Idiopathic Hypersomnia
Parasomnias
Restless Legs Syndrome
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Sleep and Wakefulness Disorders
Prevention
Treatment
Prognosis
22: Coma and Impaired Consciousness
Vegetative State and Minimally Conscious State
Locked-in Syndrome
Brain Death
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Coma and Impaired Consciousness
Prevention
Treatment
Prognosis
Glossary
: Prevalence and Incidence in Neuroepidemiology
World Population
Aging of the Population
Life Expectancy
Distribution of Neurological Disorders by Gender and Age
Prevalence of Neurological Disorders
Incidence of Neurological Disorders
Global Epidemiology of Neurological Disorders
Global Death Rates from Neurological Disorders
Disability-adjusted Life Years for Neurological Disorders
Burden of Neurological Disorders
2: Neurologic Examination
History
Assessing Mental Conditions
Assessing the Cranial Nerves
Assessing Sensation
Assessing the Motor System
Assessing Muscle Strength
Assessing Coordination, Position, Pain, and Gait
Assessing Reflexes
Assessing the Autonomic Nervous System
Cerebrovascular Examination
3: Neurologic Tests and Procedures
Magnetic Resonance Imaging
Computed Tomography in Neurologic Disorders
Duplex Doppler Ultrasonography
Echoencephalography
Electroencephalography
Electromyography
Cerebral Catheter Angiography
Lumbar Puncture
Nerve and Muscle Biopsy
4: Neurotransmission
Major Neurotransmitters
Acetylcholine
Glutamate and Aspartate
GABA
Serotonin
Dopamine
Norepinephrine
Endorphins and Enkephalins
Part II: Neurologic Disorders
5: Pain
Development of Pain
Acute Pain
Chronic Pain
Neuropathic Pain
Complex Regional Pain Syndrome
6: Meningitis
Types of Meningitis
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Meningitis
Prevention
Treatment
Prognosis
7: Brain Infections
Encephalitis
Brain Abscesses
Helminthic Brain Infections
Rabies
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Brain Infections
Prevention
Treatment
Prognosis
8: Headache
Cluster Headache
Migraine
Post-lumbar Puncture Headache
Tension Headache
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Headache
Prevention
Treatment
Prognosis
9: Function and Dysfunction of the Cerebral Lobes
Agnosia
Amnesias
Transient Global Amnesia
Aphasia
Apraxia
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Cerebral Lobe Dysfunction
Prevention
Treatment
Prognosis
10: Stroke
Ischemic Stroke
Transient Ischemic Attack
Intracerebral Hemorrhage
Subarachnoid Hemorrhage
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Stroke
Prevention
Treatment
Prognosis
11: Seizure Disorders
Types of Seizures
Generalized Seizures
Partial Seizures
Status Epilepticus
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Seizure Disorders
Suicide and Epilepsy
Prevention
Treatment
Prognosis
12: Delirium and Dementia
Delirium
Alzheimer’s Disease
Vascular Dementia
Lewy Body Dementia
Parkinson’s Disease Dementia
Frontotemporal Dementia
HIV-associated Dementia
Chronic Traumatic Encephalopathy
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Delirium and Dementia
Prevention
Treatment
Prognosis
13: Movement and Cerebellar Disorders
Chorea and Athetosis
Dystonias
Ataxia Syndrome
Huntington’s Disease
Myoclonus
Parkinson’s Disease
Tremor
Cerebellar Disorders
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Movement and Cerebellar Disorders
Prevention
Treatment
Prognosis
14: Demyelinating Disorders
Multiple Sclerosis
Neuromyelitis Optica
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Demyelinating Disorders
Prevention
Treatment
Prognosis
15: Autonomic Nervous System Disorders
Autonomic Neuropathies
Horner Syndrome
Multiple System Atrophy
Pure Autonomic Failure
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Autonomic Nervous System Disorders
Prevention
Treatment
Prognosis
16: Motor Unit and Peripheral Nervous System Disorders
Motor Unit Disorders
Myasthenia Gravis
Amyotrophic Lateral Sclerosis
Isaac’s Syndrome
Guillain-Barré Syndrome
Stiff-person Syndrome
Chronic Inflammatory Demyelinating Polyneuropathy
Hereditary Neuropathies
Nerve Root Disorders
Peripheral Neuropathy
Mononeuropathies
Multiple Mononeuropathy
Polyneuropathy
Spinal Muscular Atrophies
Thoracic Outlet Compression Syndromes
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Motor Unit and Peripheral Nervous System
Disorders
Prevention
Treatment
Prognosis
17: Prion Diseases
Creutzfeldt-Jakob Disease
Fatal Insomnia
Kuru
Gerstmann-Sträussler-Scheinker Disease
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Prion Diseases
Prevention
Treatment
Prognosis
18: Spinal Cord Disorders
Cervical Spondylosis
Spinal Cord Compression
Spinal Cord Infarction
Spinal Epidural Abscess
Spinal Subdural and Epidural Hematoma
Hereditary Spastic Paraparesis
Syrinx of the Spinal Cord
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Spinal Cord Disorders
Prevention
Treatment
Prognosis
19: Neuro-ophthalmologic and Cranial Nerve Disorders
Conjugate Gaze Palsies
Internuclear Ophthalmoplegia
Third Cranial Nerve Disorders
Fourth Cranial Nerve Disorders
Sixth Cranial Nerve Disorders
Trigeminal Neuralgia
Hemifacial Spasm
Glossopharyngeal Neuralgia
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Neuro-ophthalmologic and Cranial Nerve
Disorders
Prevention
Treatment
Prognosis
20: Brain and Spinal Tumors
Classifications of Brain Tumors
Meningioma
Glioma
Acoustic Neuroma
Pituitary Tumors
Primary Lymphoma of the Brain
Brain Tumors in Children
Spinal Cord Tumors
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Brain and Spinal Tumors
Prevention
Treatment
Prognosis
21: Sleep and Wakefulness Disorders
Circadian Rhythm Sleep Disorders
Snoring
Insomnia and Excessive Daytime Sleepiness
Narcolepsy
Idiopathic Hypersomnia
Parasomnias
Restless Legs Syndrome
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Sleep and Wakefulness Disorders
Prevention
Treatment
Prognosis
22: Coma and Impaired Consciousness
Vegetative State and Minimally Conscious State
Locked-in Syndrome
Brain Death
Etiology and Risk Factors
Pathophysiology
Clinical Manifestations
Diagnosis
Global Incidence and Prevalence
Age-Specific Incidence
Global Mortality of Coma and Impaired Consciousness
Prevention
Treatment
Prognosis
Glossary
- Edition: 1
- Latest edition
- Published: May 15, 2023
- Language: English
JM
Jahangir Moini
Dr. Moini is an international author of 38 medical textbooks for various publishers including Elsevier, McGraw-Hill, Pearson, Jones & Bartlett Learning, Cengage Learning, and Routledge. In addition to continuing his venture as an author, he has been a professor for over 40 years. He is a retired professor with the Eastern Florida State College Science & Health Department. Previously, Dr. Moini was an assistant professor at Tehran University Medical School, Department of Epidemiology and Preventive Medicine. For 18 years, he was the Director of Epidemiology for the Brevard County Health Department. He was also Director of Allied Health at Everest University for 15 years.
Affiliations and expertise
Retired Professor, Science and Health Department, Eastern Florida State College, FL, USAAG
Amparo Gutierrez
Dr. Gutierrez is a neurologist with the Orlando Health Neuroscience and Rehabilitation Institute Neurology Group. She is a Diplomat of the American Board of Psychiatry and Neurology, American Board of Electrodiagnostic Medicine, and American Board of Neuromuscular Medicine. She also is a fellow of the American Association of Neurological Surgeons and American Academy of Neurology. Dr. Gutierrez earned her medical degree from East Central University in the Dominican Republic. Her extensive post-graduate training includes a residency in adult psychiatry at St. Vincent’s Medical Center, New York; neurology residency at Louisiana State University (LSU), New Orleans; child psychiatry fellowship at St. Luke’s–Roosevelt Hospital, New York; and clinical neurophysiology fellowship, LSU School of Medicine. In 2010 Dr. Gutierrez was a founding member of the ALS Multidisciplinary Clinic at LSU Health Science Center. She worked collaboratively with the Muscular Dystrophy Association and ALS Association providing care to patients and their families. She has been the principal investigator for many research trials related to MS with more than 20 years of clinical experience with MS and has held leadership roles with the National Multiple Sclerosis Society.
Affiliations and expertise
Neurologist, The Orlando Health Neuroscience and Rehabilitation Institute Neurology Group, FL, USANA
Nicholas Avgeropoulos
Dr. Avgeropoulos is the co-director of the brain and spine tumor program at Orlando Health / UF Health Cancer Center. His specialties are in neuro-oncology and cancer neurology.
Affiliations and expertise
Co-director, Brain and Spine Tumor Program, Orlando Health / UF Health Cancer Center, FL, USARead Clinical Neuroepidemiology of Acute and Chronic Disorders on ScienceDirect