Fragile X and Related Autism Spectrum Disorders
- 1st Edition, Volume 173 - November 17, 2023
- Imprint: Academic Press
- Editor: Michel J. Hurley
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 3 7 2 9 - 7
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 3 7 3 0 - 3
Fragile X and Related Autism Spectrum Disorders, Volume 172 in the International Review on Neurobiology series, highlights new advances in the field, with this new volume presen… Read more
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Request a sales quoteFragile X and Related Autism Spectrum Disorders, Volume 172 in the International Review on Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on The dopamine hypothesis of Autism Spectrum Disorder: a comprehensive analysis of the evidence, A Review of the Use of Psychotropic Medication to Address Challenging Behavior in Neurodevelopmental Disorders, Lipid metabolism alterations in fragile X syndrome and other neurodevelopmental disorders, Genesis, modelling and methodological remedies to autism heterogeneity, Toward an Understanding of the Role of the Exposome on Fragile X Phenotypes, Glial-mediated dysregulation of neurodevelopment in Fragile X Syndrome, and more.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in International Review of Neurobiology series
- Updated release includes the latest information on Fragile X and Related Autism Spectrum Disorders
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- Cover image
- Title page
- Table of Contents
- Series Page
- Copyright
- Contributors
- Preface
- References
- Chapter One: The dopamine hypothesis of autism spectrum disorder: A comprehensive analysis of the evidence
- Abstract
- Abbreviations
- 1 Introduction
- 2 Overview of the dopamine hypothesis of ASD
- 3 The analysis of the evidence
- 4 The predictions of the dopamine hypothesis of ASD
- 5 The future
- 6 Conclusion
- References
- Chapter Two: A review of the use of psychotropic medication to address challenging behaviour in neurodevelopmental disorders
- Abstract
- 1 Challenging behaviour
- 2 Prevalence within neurodevelopmental disorders
- 3 Contributing factors to challenging behaviour
- 4 Impact of challenging behaviour
- 5 Effectiveness of psychotropic medication for challenging behaviour
- 6 Psychotropic medication effects on the relationship between challenging behaviour and environmental events
- 7 Conclusion
- References
- Chapter Three: Involvement of brain metabolism in neurodevelopmental disorders
- Abstract
- 1 Introduction
- 2 Neurodevelopmental disorders
- 3 Involvement of endothelial cells
- 4 Involvement of pericytes
- 5 Involvement of astrocytes
- 6 Involvement of neurons
- 7 Conclusions
- Acknowledgments
- References
- Chapter Four: Cholesterol alterations in fragile X syndrome, autism spectrum disorders and other neurodevelopmental disorders
- Abstract
- 1 Introduction
- 2 Cholesterol metabolism
- 3 Alterations of cholesterol metabolism in neurodevelopmental disorders
- 4 Conclusion
- References
- Chapter Five: Toward an understanding of the role of the exposome on fragile X phenotypes
- Abstract
- 1 Fragile X syndrome
- 2 The exposome
- 3 Gene–environment interactions in FXS
- 4 Possible molecular mechanisms
- 5 Diet rigor in preclinical research
- 6 Nutrition policy and newborn screening
- 7 Conclusions and future directions
- References
- Chapter Six: How dendritic spines shape is determined by MMP-9 activity in FXS
- Abstract
- 1 Introduction
- 2 Concluding remarks
- References
- Chapter Seven: Glial-mediated dysregulation of neurodevelopment in Fragile X Syndrome
- Abstract
- 1 Introduction
- 2 Pathological cellular development within the FXS brain
- 3 Astrocyte-mediated developmental processes affected in FXS
- 4 Concluding statements
- References
- Edition: 1
- Volume: 173
- Published: November 17, 2023
- Imprint: Academic Press
- No. of pages: 322
- Language: English
- Hardback ISBN: 9780443137297
- eBook ISBN: 9780443137303
MH
Michel J. Hurley
Dr. Michael Hurley is a Research Fellow in the Clinical and Movement Neurosciences of UCL Queen Square Institute of Neurology, Faculty of Brain Sciences.
Affiliations and expertise
Research Fellow, Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, UKRead Fragile X and Related Autism Spectrum Disorders on ScienceDirect