Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders
- 1st Edition, Volume 168 - February 1, 2023
- Imprint: Academic Press
- Editors: Lori Knackstedt, Marek Schwendt
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 9 3 9 4 - 4
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 9 3 9 5 - 1
Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders, Volume 168 in the International Review of Neurobiology series, highlights advances in the field, with t… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteMetabotropic Glutamate Receptors in Psychiatric and Neurological Disorders, Volume 168 in the International Review of Neurobiology series, highlights advances in the field, with this new volume presenting interesting chapters on topics such as mGlu receptors in Parkinson’s disease, Metabotropic glutamate receptors in estradiol-mediated motivated behaviors in females, mGlu regulation of sleep, Implications for sleep disruptions in psychiatric disorders, Mechanisms of mGlu receptor trafficking; alterations by methamphetamine, Group I mGlu and cocaine seeking, The role of mGlu receptors in fear and anxiety, Regulation of Alcohol Consumption, Reward, Dependence, and Perception by Metabotropic Glutamate Receptor Signaling, and mGlu5 as a biomarker for psychiatric disorders.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in the International Review of Neurobiology serials
- Updated release includes the latest information on metabotropic glutamate receptors in psychiatric and neurological disorders
Undergraduates, graduates, academics, and researchers in the field of Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders
1. mGlu receptors in Parkinson’s disease
Phillipe Huot
2. Metabotropic glutamate receptors in estradiol-mediated motivated behaviors in females
Caroline Johnson and Paul Mermelstein
3. mGlu regulation of sleep, and implications for sleep disruptions in psychiatric disorders
Robert Gould
4. Mechanisms of mGlu receptor trafficking; alterations by methamphetamine
Peter Hamor and Marek Schwendt
5. Group I mGlu and cocaine seeking
Karen Szumlinksi and Marina Wolf
6. The role of mGlu receptors in fear and anxiety
Courtney Wilkinson, Harrison Blount and Lori Knackstedt
7. Regulation of Alcohol Consumption, Reward, Dependence, and Perception by Metabotropic Glutamate Receptor Signaling
Reginald Cannady
8. mGlu5 as a biomarker for psychiatric disorders
Ruth Asch and Irina Esterlis
Phillipe Huot
2. Metabotropic glutamate receptors in estradiol-mediated motivated behaviors in females
Caroline Johnson and Paul Mermelstein
3. mGlu regulation of sleep, and implications for sleep disruptions in psychiatric disorders
Robert Gould
4. Mechanisms of mGlu receptor trafficking; alterations by methamphetamine
Peter Hamor and Marek Schwendt
5. Group I mGlu and cocaine seeking
Karen Szumlinksi and Marina Wolf
6. The role of mGlu receptors in fear and anxiety
Courtney Wilkinson, Harrison Blount and Lori Knackstedt
7. Regulation of Alcohol Consumption, Reward, Dependence, and Perception by Metabotropic Glutamate Receptor Signaling
Reginald Cannady
8. mGlu5 as a biomarker for psychiatric disorders
Ruth Asch and Irina Esterlis
- Edition: 1
- Volume: 168
- Published: February 1, 2023
- No. of pages (Hardback): 430
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780323993944
- eBook ISBN: 9780323993951
LK
Lori Knackstedt
Prof. Lori Knackstedt has a long-standing interest in studying the pathological changes in brain and behavior which occur in response to addictive drugs. For the past nine years, her work has focused on identifying neuroadaptations in the glutamate neurotransmitter system produced by chronic self-administration of addictive drugs such as nicotine, alcohol and cocaine. She then target these neuroadaptations with translational compounds to reduce drug-seeking. To that end, her research involves assessing brain changes in reward circuitry following self- administration of addictive drugs using western blotting, immunohistochemistry, and microdialysis.
Prof. Knackstedt began her independent research career as a Research Assistant Professor at the Medical University of South Carolina in 2009. In Fall 2012, she began a tenure-track position in the Psychology Department at UF, where she now run the Neurobiology of Addiction Research Lab. She supervises three graduate students, one post-doctoral fellow and 7 undergraduates.
Affiliations and expertise
Associate Professor, Department of Psychology, College of Liberal Arts and Sciences, University of Florida, FL, USAMS
Marek Schwendt
Dr. Schwendt is an Assistant Professor in the Department of Psychology at the University of Florida, Gainesville, FL. His research focuses on psychostimulant induced neuroplasticity underlying persistent drug-seeking and cognitive impairments.
Dr. Schwendt completed his M.S. in Comenius University, Bratislava, Slovakia, and his Ph.D. in the Institute of Exp. Endocrinology & University of P.J. Safarik, Bratislava, Slovakia. He completed his Postdoctoral Fellowship in the Medical University of South Carolina, Charleston, SC
Dr. Schwendt is interested in what causes drug addiction to be a chronic relapsing disorder. He is interested in identifying cellular and molecular mechanisms underlying relapse and drug-induced cognitive deficits which persist well into abstinence. His research utilizes an animal model with high-face validity for human addiction: operant drug self-administration in combination with tasks designed to test memory performance in animals. In particular, his research attempts to elucidate the role of modulatory proteins that ‘fine-tune’ synaptic transmission during development of drug-induced neural plasticity, and further, to investigate whether in vivo manipulation of these proteins can attenuate or reverse drug-seeking and drug-induced cognitive deficits. Dr. Schwendt believes that characterization of the molecular underpinnings of the long-lasting behavioral consequences of repeated drug administration will provide critical insight into the psychopathology of drug addiction and related psychiatric disorders (including schizophrenia and depression).
Affiliations and expertise
Assistant Professor, Department of Psychology, University of Florida, FL, USARead Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders on ScienceDirect