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Elsevier

Books in Life sciences

  • Guide to Plant Transcription Factors

    • 1st Edition
    • Aryadeep Roychoudhury
    • English
    Guide to Plant Transcription Factors is the first comprehensive resource on the dynamics of transcription factor function in plants, covering their roles in process regulation, stress management, post-translational modification, and epigenetic control. The book explores how transcription factors can be manipulated or engineered for crop improvement, offering insights into their regulatory mechanisms and practical applications.Transcr... factors bind to upstream regions of target genes and recruit additional proteins, often facilitating chromatin remodeling to enable further binding. They play critical roles in diverse physiological processes, including seedling development, shoot and root growth, flowering, fruit ripening, seed maturation, nitrogen fixation, and photosynthesis. Plant transcription factors belong to numerous families, each with distinct mechanisms and functions. They also govern plant responses to pathogens and tolerance to abiotic stresses through complex gene regulatory networks.This volume provides a systematic overview of recent advances in transcription factor research, their relationship with stress tolerance, and the roles of individual transcription factors in plant systems. Featuring contributions from leading scientists worldwide, Guide to Plant Transcription Factors is an essential reference for researchers, academics, and advanced students in plant biology and biotechnology.

  • The Cytokines of the Immune System

    The Role of Cytokines in Disease Related to Immune Response
    • 2nd Edition
    • Zlatko Dembic
    • English
    Cytokines of the Immune System: The Role of Cytokines in Disease Related to Immune Response, Second Edition is a comprehensive and essential resource for graduate and postgraduate training of physicians, dentists, biomedical specialists, and those interested in scientific research in biology and biochemistry. The book provides an up-to-date, textbook-like description of immunology, focusing on the critical role of cytokines in immune responses. With advancements in cytokine research and signal transduction, this new and improved edition offers a deeper understanding of cytokine-receptor interactions, supported by novel figures based on crystal-structure conformations from the protein database.These insights are invaluable for inspiring new drug designs and therapeutic strategies. The book delivers a thorough overview of immunology, detailing the development and regulation of the immune system, with a special focus on cytokines. It presents an upgraded description of interleukins, immune-modulatory cytokines, and chemokines, exploring their structure, sources, functions, receptors, disease associations, and therapeutic potentials. This edition also introduces the latest information on innate lymphoid cells and their cytokines, as well as their adaptive immunity counterparts. A dedicated chapter on the cytokine storm provides critical insights into this phenomenon.

  • Nanomedicine in Oncology

    Unveiling Materials, Diagnostics, and Clinical Implications
    • 1st Edition
    • Ajay Kumar + 1 more
    • English
    Nanomedicine in Oncology: Unveiling Materials, Diagnostics, and Clinical Implications is a comprehensive and insightful exploration into the intersection of nanotechnology and cancer treatment. The book provides an in-depth look at the historical foundations, current advancements, and future possibilities, particularly as they apply to oncology. Sections cover both the translation of nanomedicine research into clinical practice and explore various therapeutic applications, including nanoparticle-based chemotherapy, immunotherapy, photothermal and photodynamic therapy, and gene therapy utilizing nanocarriers. Finally, the book provides concluding remarks and an outlook on continued growth and potential in oncology, summarizing key insights and looking forward to future advancements.The book offers valuable perspectives for research and clinical application, fostering a comprehensive understanding of nanomedicine's impact on cancer treatment. It's insights and knowledge make it a globally relevant and impactful resource in the domain of nanomedicine in oncology.

  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 43
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 43 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • ESKAPE Pathogens

    Virulence, Resistance, and Management
    • 1st Edition
    • Karthikeyan Ramalingam
    • English
    ESKAPE Pathogens: Virulence, Resistance, and Management provides comprehensive coverage on ESKAPE pathogens, including their virulence mechanisms, resistance patterns, and challenges in their management. The book offers the latest information on ESKAPE pathogens' pathogenicity, mechanisms of antibiotic resistance, and innovative approaches to manage these pathogens. It explores recent advancements in the field of genomics, proteomics, and transcriptomics that could potentially provide valuable insights into the mechanisms and genetic basis of antibiotic resistance in ESKAPE pathogens. Finally, the book highlights the need for alternative treatment options and innovative management strategies to combat the emergence of multidrug-resistant strains.This is a helpful resource to researchers, clinicians, educators, industry professionals, and advanced students interested in the latest research and strategies for combating multidrug-resistant pathogens.

  • Modern fMRI

    Practical Lessons and Insights
    • 1st Edition
    • Andrew Jahn
    • English
    The field of neuroimaging with functional magnetic resonance imaging (fMRI) is developing at a rapid pace, with a seemingly endless number of software packages, statistical methods, and different ways to organize and analyze neuroimaging data. Among such a wide variety of options, and with so many seemingly conflicting pieces of advice on the “correct” way of analyzing neuroimaging data, knowing what decisions to make is a difficult task. Modern fMRI: Practical Lessons and Insights provides an up-to-date, holistic overview of the field of fMRI, familiarizing the reader with the latest trends in neuroimaging, such as standardized data organization and preprocessing, advances in functional connectivity and machine learning, and current guidelines in data and code sharing. This includes advice about best practices in preprocessing, statistical modeling, QA checks, and some of the latest tools and concepts to be familiar with, including fMRIPrep, OpenNeuro.org, Open Science practices, and Jupyter notebooks

  • Laboratory Diagnosis of Inherited Metabolic Diseases

    • 2nd Edition
    • Uttam Garg + 2 more
    • English
    Laboratory Diagnosis of Inherited Metabolic Diseases, Second Edition provides the most up-to-date guidance on laboratory test selection and interpretation, illustrated metabolic pathways, and information on clinical presentation, genetics, pathogenesis, treatment, and prognosis of these diseases. Since the first edition and the expansion of newborn screening, an increasing number of healthcare providers are encountering metabolic disorders, so selecting and interpreting tests can be challenging. This fully revised edition offers simple and practical approaches to understanding metabolic diseases, assisting in the selection of tests for confirmatory diagnosis and clinical follow-up.Biochemica... genetic testing is a key laboratory medicine discipline for evaluating, diagnosing, and treating inherited metabolic diseases (IMDs). These tests are complex and specialized, and use a variety of specimens, including blood, urine, plasma, and cerebrospinal fluid. The tests evaluate enzyme activity, protein function, and metabolite levels, such as fatty acids, amino acids, and organic acids.

  • Diagnosis and Analysis of Glaucoma using AI and ML for Medical Imaging

    • 1st Edition
    • Mohammad Sufian Badar
    • English
    Diagnosis and Analysis of Glaucoma using AI and ML for Medical Imaging highlights the importance of early detection while also discussing and updating on current treatment options to slow disease progression, emphasizing the role of AI and ML in improving diagnosis and management. Sections explore causes, symptoms, diagnostic challenges, and treatment strategies for glaucoma, integrating insights on how artificial intelligence and machine learning models can enhance healthcare delivery. Practical case studies and discussions on how accessible AI tools can be utilized by healthcare workers, NGOs, students, and researchers to address diagnostic barriers prevalent in resource-limited settings are included. This targeted resource is aimed at increasing understanding of this often asymptomatic, progressive eye disease, particularly in developing countries. Healthcare professionals, students, and policymakers will find this resource valuable with its straightforward, easy to understand, curriculum-aligned content. Its emphasis on practical applications and awareness-building make it a valuable tool for advancing glaucoma care and fostering interdisciplinary collaboration in eye health.

  • Neuroscience for Sleep Medicine Part B

    • 1st Edition
    • Volume 303
    • English
    Neuroscience for Sleep Medicine series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advances in Sugarcane Research: From Molecular Insights to Field Applications

    • 1st Edition
    • Volume 119
    • English
    Advances in Sugarcane Research: From Molecular Insights to Field Applications presents a comprehensive and integrative overview of contemporary sugarcane science, bridging fundamental discoveries with crop modeling and climate change. As one of the world’s most important crops for sugar and bioenergy production.This volume brings together leading experts to explore advances across multiple scales of research—from genomics, molecular biology, and genetic improvement to plant physiology, stress responses, and crop management. Emerging approaches such as omics technologies, artificial intelligence, and functional genomics are addressed as a way to transform sugarcane breeding and accelerating the development of climate-resilient cultivars. In addition to molecular and physiological perspectives, the book addresses key aspects of agronomy, including plant nutrition, soil constraints, root system dynamics, and sustainable management practices. Special attention is given to abiotic stresses such as drought and ozone, as well as their underlying mechanisms and implications for sugarcane growth. The integration of crop modeling and agrometeorology further provides tools for predicting crop performance and supporting decision-making under limiting environmental conditions. Overall, this volume aims to serve as a key reference for understanding current progress and future directions in sugarcane research.

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