Targeting Angiogenesis, Inflammation and Oxidative Stress in Chronic Diseases
Angiogenesis, Inflammation and Oxidative Stress in Chronic Diseases
- 1st Edition - January 10, 2024
- Imprint: Academic Press
- Editors: Tapan Behl, Sukhbir Singh, Neelam Sharma
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 3 5 8 7 - 3
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 3 5 8 8 - 0
Targeting Angiogenesis, Inflammation and Oxidative Stress in Chronic Diseases presents recent advances in the vivid molecular pathways targeting angiogenesis, inflammation, and ox… Read more
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Request a sales quoteTargeting Angiogenesis, Inflammation and Oxidative Stress in Chronic Diseases presents recent advances in the vivid molecular pathways targeting angiogenesis, inflammation, and oxidative stress that contribute very widely to the genesis of chronic diseases. The books highlights drugs from natural and synthetic origins in the management/prevention/treatment of diseases, along with the drug delivery approaches. The book’s authors from various key institutions around the globe deliver well-structured and designed chapters. The systematic presented information and knowledge will surely aid consistency and continuity. The multifaceted book is enriched with deep scientific content. Each chapter clearly defines the facts, the emerging role of molecular pathways, and targets and focus, along with key challenges and future directions that will provide new areas for researchers to explore new targets in the domain.
- Focuses on the pathogenesis of the disease, along with the molecular mechanism of action
- Includes updates on strategic design/delivery of drugs targeting angiogenesis, inflammation, and oxidative stress
- Provides recent advancements in the field of pathogenesis of chronic diseases
Researchers, students, teachers, industry professionals and many others who are exploring novel targets, molecular pathways, and drug delivery approaches in chronic diseases. Pharmaceutical companies, pharmaceutical institutions, academic institutions, and senior academic researchers, Students/researchers working in the field of targeting molecular pathways involved in pathogenesis of chronic disease, drug discovery and drug delivery will find the book useful as the complete information gathered in the book can be adopted and endorsed
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- About the editors
- 1 Understanding the role of angiogenesis, inflammation and oxidative stress in diabetes mellitus: Insights into the past, present and future trends
- Abstract
- 1 Introduction
- 2 Types of diabetes mellitus
- 3 National and international prevalence
- 4 Pathophysiology of diabetes mellitus
- 5 Oxidative stress in diabetes mellitus
- 6 Inflammation in diabetes mellitus
- 7 Role of angiogenesis in diabetes mellitus
- 8 Management of diabetes mellitus
- 9 Treatment of diabetes mellitus
- 10 Innovative drugs delivery systems for treatment of diabetes mellitus
- 11 Conclusion and future perspectives
- References
- 2 Targeting angiogenesis, inflammation, and oxidative stress in obesity
- Abstract
- Acknowledgments
- 1 Introduction
- 2 Pathophysiology of obesity
- 3 Oxidative stress and inflammation in the pathogenesis of obesity
- 4 Role of angiogenesis in the development of obesity
- 5 Molecular mechanisms relating inflammation to obesity
- 6 Treatment for obesity
- 7 Advanced drug therapies targeting angiogenesis and obesity
- 8 Conclusion and future perspective
- References
- 3 Molecular mechanism(s) of angiogenesis, inflammation, and oxidative stress in cancer
- Abstract
- Acknowledgments
- 1 Introduction
- 2 Molecular role of angiogenesis in cancer
- 3 Inflammation in cancer
- 4 Oxidative stress in cancer
- 5 Pathogenesis with emphasis on molecular pathways involved
- 6 Drug targeting angiogenesis, inflammation, and oxidative stress in cancer treatment
- 7 Strategic drug delivery approaches
- 8 Conclusion and future perspectives
- References
- 4 Unraveling the enigma of rheumatoid arthritis: Exploring etiology, pathophysiology and its treatment
- Abstract
- 1 Introduction
- 2 Pathogenesis of rheumatoid arthritis
- 3 Drugs targeting angiogenesis and inflammation in the management/treatment
- 4 Conclusion and future perspectives
- References
- 5 Inflammatory bowel diseases (IBDs)
- Abstract
- Acknowledgments
- 1 Introduction
- 2 Pathogenesis and responsible factors involved in IBD
- 3 Drugs targeting angiogenesis of inflammatory bowel disease
- 4 Oxidative stress management in inflammatory bowel disease
- 5 Probiotic and antioxidant defenses mechanism for treatment of IBD disease and other GI tract disorders
- 6 Strategic drug delivery approaches in IBD
- 7 Conventional drug delivery approach (CDDA) for IBD
- 8 Colonic drug delivery systems approach (CDDSA) for IBD
- 9 Advance drug delivery approach (ADDA) for IBD
- 10 Conclusion and future perspectives
- References
- 6 Natural and synthetic agents targeting angiogenesis, oxidative stress, and inflammation in psoriasis
- Abstract
- 1 Introduction
- 2 Clinical types of psoriasis
- 3 Role of oxidative stress and inflammation in psoriasis
- 4 Role of angiogenesis in psoriasis
- 5 Currently accessible treatments
- 6 Strategic drug delivery approaches: Topical drug delivery based on nano-carrier
- 7 Conclusion and future perspectives
- References
- 7 Unveiling the pharmacological and nanotechnological aspects for the management of hypertension: State-of-the-art and future perspectives
- Abstract
- Acknowledgments
- 1 Introduction
- 2 Pathogenesis of hypertension
- 3 Role of inflammation in hypertension
- 4 Role of angiogenesis in hypertension
- 5 Role of oxidative stress in hypertension
- 6 Pharmacology investigations related to management of hypertension
- 7 Strategies for management of hypertension
- 8 Nanotechnology as a boon for the management of hypertension
- 9 Conclusion and future perspectives
- References
- 8 Decrypting the role of angiogenesis, inflammation, and oxidative stress in pathogenesis of congestive heart failure: Nanotechnology as a boon for the management of congestive heart failure
- Abstract
- Acknowledgments
- 1 Introduction
- 2 Classification of heart failure
- 3 Epidemiology
- 4 Pathophysiology of congestive heart failure
- 5 Conventional therapies
- 6 Role of nanoparticles in congestive heart failure
- 7 Current challenges of nanocardiology
- 8 Future perspectives
- 9 Conclusion
- References
- 9 Expatiating the role of angiogenesis, inflammation, and oxidative stress in angina pectoris: A state-of-the-art on the drug delivery approaches
- Abstract
- Acknowledgments
- 1 Introduction
- 2 Types of angina pectoris
- 3 Oxidative stress and inflammation in pathophysiology of angina pectoris
- 4 Role of angiogenesis in angina pectoris
- 5 Treatment for angina pectoris
- 6 Nanoparticles and their role in angina pectoris
- 7 Conclusion and future perspective
- References
- 10 Targeting angiogenesis, inflammation, and oxidative stress in Alzheimer's diseases
- Abstract
- Acknowledgments
- 1 Introduction
- 2 Molecular pathways of pathogenesis
- 3 Role of angiogenesis in AD
- 4 Role of inflammation in AD
- 5 Role of oxidative stress in AD
- 6 Natural approach in the management of AD
- 7 Synthetic approach in the management of AD
- 8 Strategic approaches for AD treatment
- 9 Conclusion and future prospective
- References
- 11 Advancement in herbal drugs for the treatment of Parkinson’s disease
- Abstract
- Acknowledgments
- 1 Introduction
- 2 Epidemiology and prevalence of PD
- 3 Apoptosis, oxidative stress, inflammation, and angiogenesis in the pathophysiology of Parkinson’s disease
- 4 Advancement in herbal drugs for the treatment of Parkinson’s disease
- 5 Nanotechnological aspects for the management of Parkinson’s disease
- 6 Conclusion and future prospectives
- References
- 12 Targeting angiogenesis, inflammation, and oxidative stress in depression
- Abstract
- Acknowledgement
- 1 Introduction
- 2 Pathogenesis with emphasis on molecular pathways involved
- 3 Drugs targeting angiogenesis, inflammation, and oxidative stress in the management/treatment depression
- 4 Strategic drug delivery approaches
- 5 Conclusion and future perspectives
- References
- 13 Role of inflammation, angiogenesis and oxidative stress in developing epilepsy
- Abstract
- Acknowledgments
- Conflict of interest
- Funding
- 1 Introduction
- 2 Epilepsy
- 3 Microvascular pathogenesis involved in epilepsy
- 4 Diagnosis
- 5 Pharmacological treatment
- 6 Recent advances in micro dysfunction management
- 7 Conclusion and future prospective
- References
- 14 Diabetic retinopathy: Stressing the function of angiogenesis, inflammation and oxidative stress
- Abstract
- Graphical abstract
- 1 Introduction
- 2 Pathophysiology
- 3 Current and novel treatment approaches for diabetes retinopathy
- 4 Recent advances in application of nanotechnology in the treatment of diabetes retinopathy
- 5 Conclusion
- 6 Future perspectives
- References
- 15 Targeting the role of angiogenesis, inflammation and oxidative stress in pathogenesis of glaucoma: Strategic nanotechnology based drug delivery approaches
- Abstract
- Acknowledgments
- 1 Introduction
- 2 Role play of angiogenesis, inflammation, and oxidative stress in the pathophysiology of glaucoma
- 3 Classification of therapeutic treatments available for management of glaucoma
- 4 Nanotechnological aspects as a paradigm in therapeutics of glaucoma
- 5 Conclusion and future perspectives
- References
- 16 Age-associated macular degeneration: Epidemiologic features, complications, and potential therapeutic approaches
- Abstract
- Acknowledgment
- Conflict of interest
- Funding
- 1 Introduction
- 2 Different types of AMD
- 3 Critical alterations during AMD
- 4 Diagnosis and symptoms
- 5 Pathogenesis of age-linked macular deterioration
- 6 Prevalence, incidence, and natural history of AMD
- 7 Risk influences and possible drugs targets for the administration of AMD
- 8 Strategic drug delivery approaches: Emerging sustained drug delivery systems in AMD
- 9 Nanotechnology for the management of AMD
- 10 Future crosstalk
- 11 Conclusion
- References
- 17 Exploring the potential role of nanotechnology as cutting-edge for management of hirsutism and gynecomastia: A paradigm in therapeutics
- Abstract
- Acknowledgments
- 1 Introduction
- 2 Pathophysiology of hirsutism
- 3 Angiogenesis, oxidative stress, and inflammation in hirsutism
- 4 Pathophysiology of gynecomastia
- 5 Drugs used for the treatment of hirsutism
- 6 Drugs used for the management/treatment of gynecomastia
- 7 Nanotechnological-based approaches for the management of hirsutism and gynecomastia
- 8 Conclusion and future perspectives
- References
- 18 Role of inflammation, oxidative stress, and angiogenesis in polycystic ovary syndrome (PCOS): Current perspectives
- Abstract
- Acknowledgment
- Conflicts of interest
- Funding
- 1 Introduction
- 2 Polycystic ovarian syndrome
- 3 Pathogenesis
- 4 Androgen and PCOS
- 5 PCOS and low-grade inflammation
- 6 PCOS and oxidative stress
- 7 PCOS and (IR) insulin resistance
- 8 PCOS and angiogenesis
- 9 Current and novel treatment approaches
- 10 Treatment for inflammation
- 11 Treatment for acne and hirsutism
- 12 Future direction
- 13 Conclusion
- References
- Index
- Edition: 1
- Published: January 10, 2024
- Imprint: Academic Press
- No. of pages: 522
- Language: English
- Paperback ISBN: 9780443135873
- eBook ISBN: 9780443135880
TB
Tapan Behl
Professor Tapan Behl is based at Amity School of Pharmaceutical Sciences, Amity University, Sahibzada Ajit Singh Nagar, Punjab, India. Dr. Tapan Behl completed his doctoral studies from Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India and thereafter worked as Post-Doctoral Researcher. His areas of interest include diabetes and associated complications, molecular pharmacology and neuropathic pain and its complications. Dr. Behl has published more than 400 research and review papers in International and National journals. He has also published International books and is continuously engaged in exploring the molecular mechanisms in diabetes and related complications, rheumatoid arthritis and obesity.
Affiliations and expertise
Professor, Amity School of Pharmaceutical Sciences, Amity University, Sahibzada Ajit Singh Nagar, Punjab, IndiaSS
Sukhbir Singh
Professor Sukhbir Singh has a PhD in Pharmaceutical Science and experience of more than 15 years in academia and research. He has 170 publications in various National/International journal of repute, 8 books, 12 books chapter and filed 19 patents to his credit. He has presented/published 40 review/research abstracts in various National/International conferences. His areas of interest in research are nanotechnology/liposome/niosomes/SEDDS based formulation development and solubility enhancement of BCS class II drugs. He has expertise in operation of various statistical analysis tools
Affiliations and expertise
Department of Pharmaceutics, MM College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, Haryana, IndiaNS
Neelam Sharma
Dr. Neelam Sharma, PhD in Pharmaceutical Science has experience of more than 13 years in academics and research. She is highly self-determined and organized pharmaceutical research professional. She has 140 publications in various National/International journal of repute, h-index 12 and i 10-index 20, 08 books, 12 books chapter and filed 19 patents to his credit. She has presented/published 35 review/research abstracts in various National/International conferences. She has completed 4 consultancy projects on herbal/homeopathic formulation. She and her team received IEDC, Govt of India, prototyping grant of Rs 2.5 lacs for project related to management of ARDS in COVID, held at Chitkara University, Punjab in 2020 and project has been completed in 2022. She has guided 1 PhD students and 20 M. Pharmacy students and 6 Ph.D students are pursuing PhD under her guidance.
Affiliations and expertise
Department of Pharmaceutics, MM College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, Haryana, IndiaRead Targeting Angiogenesis, Inflammation and Oxidative Stress in Chronic Diseases on ScienceDirect