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Elsevier

Books in Life sciences

  • Nanocosmeceuticals

    Innovation, Application, and Safety
    • 1st Edition
    • Malay K. Das
    • English
    Cosmetics are a fast-growing segment in the global personal care industry and the application of nanocosmeceuticals are on the rise. Conventional cosmetics greatly lack specific delivery systems, prolong effects and relatively heavy doses may be necessary. One of the common complaints of consumers is rather short-term activity of cosmetics, especially in face care products.Nanocosmece... having more advanced nutrient delivery mechanisms, carry more task specific nutrients to the skin deep where it can be metabolized and used to nourish cells. It can help to increase the aesthetic appeal of a product influencing the purchase decision of a consumer. Nanocosmeceuticals: Innovation, Application and Safety highlights the trends and applications of nanotechnology in cosmeceuticals for more advance and task specific nutrients delivery and long term effects of personal care products using liposome, solid lipid nanoparticles, nanostructured lipid carriers, transferosomes, niosomes, phytosomes, nanoemulsions, silver nanoparticles, chitin nanofibrils etc. It also provides the detailed information on regulatory laws, safety and marketing aspects of cosmeceuticals.This book offers an indispensable guide for professors, researchers, students, formulation chemists as well as formulation scientists in academia and industry; beauticians and decision-makers in consumer organizations.

  • New Aspects of Meat Quality

    From Genes to Ethics
    • 2nd Edition
    • Peter P. Purslow
    • English
    New Aspects of Meat Quality, Second Edition continues to be the leading source of scientific information for what constitutes meat quality for consumers, marketers and producers in the 21st century. The book includes traditional measures of meat quality such as texture, water holding, color, flavor/aroma, safety/microbiology and processing characteristics as well as quality assurance schemes, organic/free range, ethical meat production, and the desirability of genetically modified organisms, amongst others. Users will find comprehensive coverage on developments in our understanding of how muscle structure affects the eating qualities of cooked meat, along with techniques for measuring, predicting and producing meat quality. In addition, the book covers how these new techniques help us minimize variability in eating quality and/or maximize value. The book's final section identifies the current qualities of consumer and public perceptions and what is sustainable, ethical, desirable and healthy in meat production and consumption.

  • Precision Medicine

    • 1st Edition
    • Volume 190
    • David B. Teplow
    • English
    Precision Medicine, Volume 190 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Evolution of Biomarkers and Strategies for Integrating the Precision Philosophy to Guide Monitoring of Individualized Autoimmunity Conditions and to Implement the Philosophy into Clinical Practice, Precision Medicine in Epilepsy, The use of ASOs for personized medicine, Adult medicine, EGFR, NF-KB signal and regulatory noncoding RNAs in cancer, Precision medicine with multi-omics strategies, deep phenotyping, and predictive analysis, The Paradox of Personalized Medicine, and more.

  • Handbook of Neuro-Oncology Neuroimaging

    • 3rd Edition
    • Herbert B. Newton
    • English
    With treatment approaches and the field of neuro-oncology neuroimaging changing rapidly, this third edition of the Handbook of Neuro-Oncology Neuroimaging is very relevant to those in the field, providing a single-source, comprehensive, reference handbook of the most up-to-date clinical and technical information regarding the application of neuroimaging techniques to brain tumor and neuro-oncology patients. This new volume will have updates on all of the material from the second edition, and in addition features several new important chapters covering diverse topics such as imaging for the use of Laser Interstitial Thermal Therapy, advanced imaging techniques in radiation therapy, therapeutic treatment fields, response assessment in clinical trials, surgical planning of neoplastic disease of the spine, and more. Sections first overview neuro-oncological disorders before delving into the physics and basic science of neuroimaging and great focus on CT and MRI. The book then focuses on advances in the neuroimaging of brain tumors and neuroimaging of specific tumor types. There is also discussion of neuroimaging of other neuro-oncological syndromes. This book will serve as a resource of background information to neuroimaging researchers and basic scientists with an interest in brain tumors and neuro-oncology.

  • MRI Atlas of the Infant Rat Brain

    Brain Segmentation
    • 1st Edition
    • Dusica Bajic + 2 more
    • English
    MRI Atlas of the Infant Rat Brain: Brain Segmentation features an entirely new coronal, sagittal and horizontal set of tissue cut in regular 9 µm intervals with accompanying photographs of MRI data and color drawings of selected brain regions in the three planes. The use of the single brain allows for greater consistency between sections, while color masking offers advances in manual segmentation techniques with increased refinement in the definition of brain areas. Readers will benefit from uniform and consistent manual tissue segmentation of MRI data in an infant rat brain. This volume provides readers the first infant rat brain MRI atlas and a valuable resource in research analyses of the developing brain for structural and functional MRI analyses.

  • Genetics and Neurobiology of Down Syndrome

    • 1st Edition
    • Bani Bandana Ganguly
    • English
    Genetics and Neurobiology of Down Syndrome provides a thorough review of the genetic etiology and mechanisms of trisomy 21. The author discusses the history of the syndrome, along with the clinical features and health consequences, including physical features, cognitive, and neurologic symptoms. Genetic counseling on pros and cons of prenatal screening and testing and associated ethical issues are explored. This unique book also covers the societal and demographic aspects as well as the future direction of therapeutic development.

  • System Vaccinology

    The History, the Translational Challenges and the Future
    • 1st Edition
    • Vijay Kumar Prajapati
    • English
    Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to control the spread of infectious diseases as well as to improve the life expectancy at global level in 20th-21st Century. This book will provide the in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecule. This book will cover the development of system vaccinology and their applications revolutionize the vaccine discovery. This will provide a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials. My purpose to write this book to educate the students and researchers with modern development in the field of vaccinology and empowering the researcher with new tools and methodology for developing potential and immunogenic vaccines. This book will be helpful to solve the curiosity of science and medical background students related with vaccinology and will be helpful to devise a new vaccine molecule to control the spread of new and emerging pathogens. Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high- throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis we are able to interrogate host responses to infections and vaccination on a systems level, thus generating important new hypotheses and discovering unknown associations between immunological parameters.

  • Autophagy Dysfunction in Alzheimer's Disease and Dementia

    • 1st Edition
    • Tadanori Hamano + 1 more
    • English
    Autophagy Dysfunction in Alzheimer’s Disease and Dementia provides an overview for researchers and clinicians on the mechanisms involved in protein degradation in Alzheimer’s. The book discusses the implication of autophagy dysfunction in these diseases and how it causes degenerated proteins, including aggregated tau and aggregated amyloid protein. Other sections explores the possibilities of potential drug development through autophagy modulation, making this a great resource on the study of how autophagy dysfunction has been linked to the accumulation of misfolded proteins that cause death of neurons in Alzheimer’s and other neurodegenerative diseases.

  • PDE Modeling of Tissue Engineering and Regenerative Medicine

    Computer Analysis in R
    • 1st Edition
    • William E. Schiesser
    • English
    PDE Modeling of Tissue Engineering and Regenerative Medicine: Computer Analysis in R presents the formulation and computer implementation of mathematical models for the forefront research areas of tissue engineering and regenerative medicine. The mathematical model discussed in this book consists of a system of eight partial differential equations (PDEs) with dependent variables. The computer-based example models are presented through routines coded in R—a quality, open-source scientific computing system that is readily available from the Internet. Formal mathematics is minimized, e.g., no theorems and proofs. Includes detailed examples that the reader can execute on modest computers.

  • Phytoconstituents and Antifungals

    • 1st Edition
    • Awanish Kumar
    • English
    Phytoconstituents and Antifungals covers a wide range of specific information on various phytoconstituents, their antifungal mode and the diagnosis and management of fungal infections. The book offers encouragement and empowers readers to re-embrace their knowledge of phytoconstituents and their various antifungal activities against most opportunistic pathogenic fungi as fungal diseases cause an estimated 1.5+ million deaths annually and over one billion people suffer from severe fungal disease. In this complex scenario, it is now clear that global warming and accompanying climate changes have resulted in increased incidence of many fungal infections. On the basis of all these factors, concerns on the occurrence of a pandemic fungal origin in the near future have been raised. In this context, to stop forgetting and underestimating fungal diseases is mandatory.

  • The Chromosome 22q11.2 Deletion Syndrome

    A Multidisciplinary Approach to Diagnosis and Treatment
    • 1st Edition
    • Donna M. McDonald-McGinn
    • English
    The Chromosome 22q11.2 Deletion Syndrome: A Multidisciplinary Approach to Diagnosis and Treatment serves as the first comprehensive, user-friendly resource on the etiology, prognosis, and recurrence risk associated with the chromosome 22q11.2 deletion syndrome. Leading international contributors cover the background, genetics, testing methods, and pathophysiology of 22q11.2DS, placing emphasis on a strong foundation for multidisciplinary treatment strategies. Written by specialists in every applicable subspecialty, such as, cardiology, immunology, endocrinology, gastroenterology, hematology, ophthalmology, neurology, and psychiatry, among other fields. This book presents an authoritative resource with full color images that enhance concept illustration and aid in real-time decision-making. As 22q11.2 deletion syndrome has become a model for understanding rare and frequent anomalies, numerous medical issues, cognitive and behavioral phenotypes, and later onset conditions, this text will become the go to resource for clinicians, researchers, trainees, and motivated family members, in gaining a full understanding of this complex chromosomal disorder.

  • Oral Delivery of Therapeutic Peptides and Proteins

    • 1st Edition
    • Puneet Tyagi + 1 more
    • English
    Oral Delivery of Therapeutic Peptides and Proteins provides a complete overview of the journey scientists pursue to attain protein and peptide oral delivery. The book highlights the physiological challenges that must be accounted for in addition to overcoming protease inhibition and acid stability issues that are commonly mentioned in this area of research. Primary topics include formulation technologies being adopted for oral delivery of proteins and peptides, modification of actives to make them more suited for oral delivery, animal models and their shortcomings in assessing oral bioavailability, and in vitro models to simulate drug absorption and transport. Academics and industry researchers working in formulation development and researchers and advanced students in biotechnology and pharmacy will find this a useful resource.

  • Sex and Gender Differences in Neurological Disease

    • 1st Edition
    • Volume 164
    • English
    International Review on Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Flavor

    From Food to Behaviors, Wellbeing and Health
    • 2nd Edition
    • Elisabeth Guichard + 1 more
    • English
    Flavor: From Food to Behaviors, Wellbeing and Health, Second Edition presents the different mechanisms of flavor perception. Broken into four parts, the first begins with coverage of flavor release in humans. Part two addresses flavor perception, from molecules to receptors and brain integration. Part three analyzes flavor perception, preferences and food intake. Finally, part four considers flavor perception and physiological status. Academics working in the areas of sensory science, food quality, nutrition and human sciences, as well as research and development professionals and nutritionists, will benefit from this important revised reference.

  • Cannabis and the Developing Brain

    • 1st Edition
    • Miriam Melis + 1 more
    • English
    Marijuana is the most commonly used psychotropic drug in the United States, after alcohol. With the legalization and decriminalization of cannabis, momentum continues to build and propelled by the reduction of stigma associated to its consumption, there is growing concern regarding the long-term impact on brain function and behavior. Cannabis and the Developing Brain aims to provide comprehensive research on the effects of cannabis during neurodevelopment stages (i.e., perinatal and adolescent ages). This book introduces readers to vivo neural circuits, molecular and cellular mechanisms affected by cannabis exposure during three different temporal windows of brain vulnerability. Second, it offers a unique insight to shared neurobiological features of cannabinoid exposure during different developmental periods. Lastly, Cannabis and the Developing Brain determines the adverse impact of developmental cannabinoid exposure on specific cognition, emotion and behaviors.

  • Twin Research for Everyone

    From Biology to Health, Epigenetics, and Psychology
    • 1st Edition
    • Adam D. Tarnoki + 3 more
    • English
    Twin Research: Biology, Health, Epigenetics, and Psychology is a comprehensive, applied resource in twinning and twin studies that is grounded in the most impactful findings from twin research in recent years. While targeted to undergraduate and graduate students, this compendium will prove a valuable resource for scholars already familiar with twin studies, as well as those coming to the field for the first time. Here, more than forty experts across an array of disciplines examine twinning and twin research methodologies from the perspectives of biology, medicine, genetic and epigenetic influences, and neuroscience. Chapters provide clear instruction in both basic and advanced research methods, family and parenting aspects of twinning, twin studies as applied across various disease areas and medical specialties, genetic and epigenetic determinants of differentiation, and academic, neurological and cognitive development. The presentation of existing studies and methods instruction empowers students and researchers to apply twin-based research and advance new studies across a range of biomedical and behavioral fields, highlighting current research trends and future directions.

  • Lipids: Update on Diagnosis and Management of Dyslipidemia, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 51-3
    • Connie B. Newman + 1 more
    • English
    In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Connie B. Newman and Alan Chait bring their considerable expertise to the topic of Lipids: Update on Diagnosis and Management of Dyslipidemia. When untreated, dyslipidemia may have serious comorbidities; in this issue, top experts cover the evaluation and management of LDL cholesterol and high triglicerides in adults and children, providing practical information that will help physicians and other health care professionals treat their patients and improve outcomes.

  • Clinical Immunology

    • 1st Edition
    • Nima Rezaei
    • English
    Clinical Immunology not only introduces the reader to the human immune system, it also covers immunology from clinical manifestation to therapeutic approaches in a wide range of conditions. Each chapter describes an introduction, the clinical manifestations, the immunopathogenesis, diagnosis, lab tests and therapeutic approaches. The book guides clinicians, researchers and students to a better understanding of the matters of immunologic-based diseases that can lead to better decision-making for patients.Because of the growing knowledge regarding the function of immune system in health and disease conditions, clinicians, researchers and students increasingly require an exclusive scientific reference to guide them on matters of immunologic-based diseases. Accordingly, despite the existence of numerous high quality references in basic and cellular/molecular immunology which deeply explain different immunologic mechanisms, there is still a knowledge gap in the field of clinical immunology.

  • L'Adulte avec un trouble dys-exécutif

    L'accompagner dans sa vie quotidienne, sociale et professionnelle
    • 1st Edition
    • Alain Moret
    • French
    Les recommandations pour la prise en charge du trouble dys-exécutif s’adressent à l’enfant, afin de faciliter son éducation et sa scolarité. Le trouble s’améliore parfois avec l’avancée en âge, mais il reste très présent à l’âge adulte. Se pose alors la question de l’autonomie au quotidien en termes de professionnalisation... d’insertion sociale et de citoyenneté pour laquelle l’entourage doit souvent développer ses propres outils car rien n’est formalisé pour accompagner l’adulte.L’ouvrage aborde les différentes situations rencontrées par l’adulte dys-exécutif, des plus anodines de la vie quotidienne aux plus personnelles ou aux plus décisives quant à son style de vie, et propose des solutions pratiques et des conseils d’adaptation ou d’aménagements pour y faire face.Plus que chez l’enfant, les stratégies proposées pour aider l’adulte dys-exécutif dans sa prise d’autonomie sont pensées pour ménager sa personnalité et son libre arbitre.La description des différentes situations intègre à la fois le vécu de l’adulte dys-exécutif et celui d’autrui, en mettant l’accent sur les quiproquos et des interprétations erronées en fonction du contexte qui peuvent générer incompréhension et perte d’estime de soi.L’ouvrage interroge chacun, qu’il soit parent ou professionnel, sur ce que signifie réellement l’inclusion dans un environnement qui n’a pas les clés pour appréhender correctement les interactions avec l’adulte dys-exécutif, la définition de son projet de vie et le respect de sa volonté.

  • Biotechnology in Healthcare, Volume 2

    Applications and Initiatives
    • 1st Edition
    • Debmalya Barh
    • English
    Biotechnology in Healthcare presents up-to-date knowledge on the emerging field of biotechnology as applied to the healthcare industry. Biotechnology has revolutionized healthcare in the last two decades by developing and introducing novel diagnostics, therapeutics, and preventive measures; whether it is noncommunicable or communicable disease, primary or secondary care, or public health, it has shown its immense potential to provide a solution to the healthcare providers, physicians, and allied health care professionals.The second volume, Applications and Initiatives, contains 19 chapters focused on the applications of biotechnology related to public healthcare, hospital management, oncology, neurodegenerative and infectious diseases, regenerative medicine, IVF, clinical trials, precision food, FMGCs, PPCPs, pharmaceuticals, and smart technologies to monitor pandemic. Further, this volume also presents government initiatives and entrepreneurship challenges in healthcare biotechnology sector.This is a valuable resource for students, biotechnologists, bioinformaticians, clinicians, and members of biomedical and healthcare fields who need to understand more about the promising developments of the emerging field of biotechnology in healthcare.

  • Epigenetics and DNA Damage

    • 1st Edition
    • Volume 33
    • Miriam Galvonas Jasiulionis
    • English
    Although scientists recognize the role of epigenetic mechanisms in DNA damage response, the complex, mechanistic interplay between chromatin regulation and DNA repair is still poorly understood. Comprehending how these processes are connected in time and space and play out in developmental processes may reveal novel directions for new research and disease treatment. Epigenetics and DNA Damage, a new volume in the Translational Epigenetics series, offers a thorough grounding in the relationship between DNA Damage, epigenetic modifications, and chromatin regulation. Early chapters address the basic science of DNA damage and its association with various epigenetic mechanisms, including DNA methylation, post-translational histone modifications, histone variants, chromatin remodeling, miRNAs, and lncRNAs. This is followed by a close discussion of DNA damage and epigenetics in metabolism, aging, cellular differentiation, immune function, stem cell biology, and cancer, tying recent research to translational application in disease understanding. Later chapters examine possible epigenetic therapies combining DNA damage induction and epigenetic alteration, as well as instructive chapters on how to analyze DNA damage and epigenetic alterations in new research.

  • A Pharmacology Primer

    Techniques for More Effective and Strategic Drug Discovery
    • 6th Edition
    • Terry P. Kenakin
    • English
    A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Sixth Edition features the latest research surrounding the application of pharmacology in drug discovery in an effort to equip readers with a deeper understanding of complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for anyone involved in drug discovery. This edition has been reorganized for better flow and clarity and includes material on new technologies for screening (virtual, DNA encoded libraires, fragment-based) and a major section on phenotypic (target agnostic) screening for new leads and determination of drug targets. With full color illustrations as well as new examples throughout, this book remains a top reference for all industry and academic scientists and students directly involved in drug discovery or pharmacologic research. New material includes a discussion of the determination of target engagement, including numerous new ways to demonstrate the physical interaction of molecules with drug targets and new drug candidates such a mRNA, gene therapy, antibodies and information on CRISPR and genomics.

  • Metals and Metalloids in Soil-Plant-Water Systems

    Phytophysiology and Remediation Techniques
    • 1st Edition
    • Tariq Aftab + 1 more
    • English
    Metals and Metalloids in Soil-Plant-Water Systems: Phytophysiology and Remediation Techniques examines the impact of metal/metalloid contamination on the plant lifecycle, along with microbes present in soil. Highlighting uptake and translocation, the book also examines antioxidant, photosynthesis and growth characteristics of plants grown in metal contaminated soil. Beginning with an introduction to different sources of soil and water pollution, chapters assess the environmental cytotoxicity pollution impact on plants, as well as how the generation of reactive oxygen and nitrogen species in plant tissues is affected. The book also discusses various soil remediation methodologies, including the potential applications of metal oxidizing microbes and nanomaterials. This is an essential resource for researchers and students interested in plant physiology, soil science, environmental science and agriculture.

  • Hazardous and Trace Materials in Soil and Plants

    Sources, Effects, and Management
    • 1st Edition
    • M. Naeem + 4 more
    • English
    Hazardous and Trace Materials in Soil and Plants: Sources, Effects and Management explores the latest advancements in reducing, avoiding and eliminating soil contaminants that challenge the health and safety of agricultural plants. With a focus on minimizing the production of those hazardous substances, controlling their distribution and ensuring safe utilization, the book explores each contributing area and provides insights toward improved, sustainable and secure production. This is an excellent reference resource on both current research and future directions from laboratory research to field applications. The combined impacts of climate change and industrialization have led to increased and diversified threats to the health of the soil in which our food crops are grown, as well as in the plants themselves. This dual-hazard scenario is increasingly recognized as a threat to not just the environment, but to global food security as agricultural soils contaminated with pollutants alter plant metabolism, thus resulting in reduced crop quality and production quantity.

  • Technologies to Recover Polyphenols from AgroFood By-products and Wastes

    • 1st Edition
    • Elisabete M.C. Alexandre + 2 more
    • English
    Technologies to Recover Polyphenols from AgroFood By-products and Wastes: Applications in Different Fields covers the most used technologies to extract and recover polyphenols from all kinds of by-products and wastes generated by the food industry, restaurant and agricultural sectors. Polyphenols are characterized by different AgroFood by-products and waste sources, hence this book explores the practical applications of these polyphenols in the development of functional foods and pharmaceutical and cosmetic products. Containing definitions, case studies, applications, literature reviews, and coverage of recent developments, this book will be a welcomed resource for food scientists, including those working in sustainability, agriculture and engineering.

  • Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI Approach

    • 1st Edition
    • Anirudh Nath + 2 more
    • English
    Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI-Based Approach exposes readers to the various existing mathematical models that define the dynamics of glucose-insulin for Type 1 diabetes patients. After providing insights into the mathematical model of patients, the authors discuss the need and emergence of new control techniques that can lead to further development of an artificial pancreas. The book presents various nonlinear control techniques to address the challenges that Type 1 diabetic patients face in maintaining their blood glucose level in the safe range (70-180 mg/dl). The closed-loop solution provided by the artificial pancreas depends mainly on the effectiveness of the control algorithm, which acts as the brain of the system. APS control algorithms require a mathematical model of the gluco-regulatory system of the T1D patients for their design. Since the gluco-regulatory system is inherently nonlinear and largely affected by external disturbances and parametric uncertainty, developing an accurate model is very difficult.

  • Post-transcriptional Gene Regulation in Human Disease

    • 1st Edition
    • Volume 32
    • Buddhi Prakash Jain + 2 more
    • English
    Post-transcriptional Gene Regulation in Human Disease, a new volume in the Translational Epigenetics book series, offers a thorough overview and discussion of post-transcriptional genetic control mechanisms and their roles across various pathologies and human developmental outcomes, along with regulatory mechanisms targeted for therapeutic approaches. The book is broadly divided in two parts: early chapters describe the basics of post-transcriptional gene regulation, associated epigenetic mechanisms, the role of RNA binding proteins, the evolution of post-transcriptional gene regulation, and methods to study these mechanisms. The second half of the book includes deeper discussion of post-transcriptional gene regulation across specific diseases and therapeutics targets. Various post-transcriptional events, including alternative splicing and polyadenylation, mRNA stability, and miRNAs and their involvement in the disease progression, are examined in detail.

  • Helicase Enzymes Part B

    • 1st Edition
    • English
    Methods in Enzymology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Respiratory Neurobiology

    Physiology and Clinical Disorders, Part I
    • 1st Edition
    • Volume 188
    • English
    Respiratory Neurobiology: Physiology and Clinical Disorders, Part One, Volume 188 is one of two volumes on the neurology of breathing. This volume focuses on the neurophysiology of breathing, while the second volume focuses on pathologies attributable to abnormalities of the neural control of breathing, breathing problems that may occur in neurological diseases, and the neurological complications of respiratory diseases.

  • The Temporal Lobe

    • 1st Edition
    • Volume 187
    • English
    The Temporal Lobe, Volume 187 covers the exponential growth of studies on the relationships between brain and language/cognition, many of which involved the temporal lobe. This volume summarizes research on the anatomy and function of the temporal lobe under both normal and pathological conditions. In addition, it discusses the interactions of the temporal lobe with other brain structures. The book highlights the role of the temporal lobe in language processing as well as vision, object, face recognition and processing. The book also discusses the temporal lobe's role in reading, speech and the processing of color, music, action and memory. Temporal lobe disorders, assessments and treatments are also covered, including encephalitis, Alzheimer’s, epilepsy, Korsakov’s syndrome, and more.

  • Imaging of Headache, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 40-3
    • Sangam Kanekar
    • English
    In this issue of Neurologic Clinics, guest editor Dr. Sangam Kanekar brings his considerable expertise to the topic of Imaging of Headache. Top experts in the field cover key topics such as headache attributed to disorder of the cranium and base of the skull; role of CT and MRI in evaluation of headache due to paranasal sinus and teeth disorder; imaging of painful ophthalmologic disorders; role of MRI and CT in the evaluation of headache in pregnancy and postpartum period; assessment and imaging of pediatric and adolescent headache; and more.

  • Synergistic Approaches for Bioremediation of Environmental Pollutants: Recent Advances and Challenges

    • 1st Edition
    • Riti Thapar Kapoor + 1 more
    • English
    Synergistic Approaches for Bioremediation of Environmental Pollutants: Recent Advances and Challenges focuses on the exploitation of various biological treatment technologies and their use to treat toxic contaminants present in industrial effluent and in restoring contaminated sites, which lacks in a more comprehensive manner in existing titles on similar topics available on the global market. The book comprises advanced biotechnologies and updated information, along with sustainable waste management developments and future directions for researchers and scientists working in the field of microbiology.

  • Hepatobiliary Cancers: Translational Advances and Molecular Medicine

    • 1st Edition
    • Volume 156
    • English
    Hepatobiliary cancer refers to primary malignant tumors originating in cells of the liver, bile ducts, and gallbladder. Globally, primary liver cancer, which includes hepatocellular carcinoma (~75 % of all cases) and intrahepatic biliary cancer or cholangiocarcinoma (~10-15 % 0f all cases) is the 6th most commonly diagnosed cancer and 3rd leading cause of cancer deaths worldwide. The vast majority of these highly malignant cancers are diagnosed at an advanced stage where treatment options are limited and patient survival outcomes are poor. The biological and therapeutic challenges posed by hepatobililiary cancers such as hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) are daunting, emphasizing a critical need to review and assess current and evolving basic, translational, and clinical research focused on addressing the critical obstacles that continue to limit progress towards achieving significant improvements in HCC and CCA clinical management and patient survival outcomes. Towards this goal, this special edition of Advances in Cancer Research is focused on providing a comprehensive, timely and authoritative reviews covering such topics of significant scientific and clinical relevance, including hepatobiliary cancer risk mechanisms and risk-predictive molecular biomarkers; causes and functional intricacies of inter- and intratumor heterogeneity; novel insights into the role of tumor microenvironment and key signaling pathways in promoting hepatobiliary cancer progression, therapeutic resistance and immunosuppression; emerging biomarkers of HCC and CCA prognosis; advances in molecular genomics for personalizing tumor classification and targeted therapies; innovative preclinical cell culture modeling for hepatobiliary cancer drug discovery; and current and emerging trends in hepatobiliary cancer molecular therapeutic targeting and immunotherapies.

  • "Venomous" Bites from "Non-Venomous" Snakes

    • 2nd Edition
    • Scott A Weinstein + 2 more
    • English
    "Venomous" Bites from "Non-Venomous" Snakes, Second Edition thoroughly examines the potential hazards associated with bites by non-front-fanged snakes (popularly, but inaccurately, called "rear-fanged snakes"). This diverse group contains approximately 80% of living snake species (approximately 2,900 species). A large proportion of these snakes were previously assigned to the family Colubridae but, as a consequence of expanding systematics investigations, have been split into multiple families and subfamilies. Many of these snakes produce venoms or oral secretions that contain toxins and other biologically active substances. A large variety of non–front-fanged snakes figure in the pet industry, yet little documented information or formal study of their potential medical importance has been published. Therefore, although the possible medical importance of many of these species has been subjected to speculation since the mid-19th century, there is a limited amount of useful descriptive information regarding the real hazard (or lack thereof) of this wide variety of snakes. The first edition of this book provided "one-stop shopping" by offering information regarding their possible toxicity and clinical relevance as well as recommendations for medical management of their bites. The second edition expands and updates the content with detailed information about the effects and medical management of bites by a broad representation of non–front-fanged species. The hypothetical venomous nature of some lizards considered as non-venomous such as the Komodo monitor or dragon and their allies, as well as the medical effects of their bites, is also examined. The dynamic taxonomy of advanced snakes is updated, and the bases for some of these fluid changes are discussed. Likewise, terminology is also updated in order to reflect the ongoing debates regarding the definition of "venom" and the balanced reinforcement of nonmedical criteria used to define the biological basis of the term "venomous."

  • 3D Lung Models for Regenerating Lung Tissue

    • 1st Edition
    • Gunilla Westergren-Thorsson + 1 more
    • English
    3D Lung Models for Regenerating Lung Tissue is a comprehensive summary on the current state of art 3D lung models and novel techniques that can be used to regenerate lung tissue. Written by experts in the field, readers can expect to learn more about 3D lung models, novel techniques including bioprinting and advanced imaging techniques, as well as important knowledge about the complexity of the lung and its extracellular matrix composition. Structured into 15 different chapters, the book spans from the original 2D cell culture model on plastic, to advanced 3D lung models such as using human extracellular matrix protein. In addition, the last chapters cover new techniques including 3D printing, bioprinting, and artificial intelligence that can be used to drive the field forward and some future perspectives. This highly topical book with chapters on everything from the complexity of the lung and its microenvironment to cutting-edge 3D lung models, represents an exciting body of work that can be used by researchers during study design, grant writing, as teaching material, or to stay updated with the progression of the field.

  • Methods in Stem Cell Biology - Part B

    • 1st Edition
    • Volume 171
    • English
    Methods in Cancer Stem Cell Biology: Part B, Volume 171 in the Methods in Cell Biology series highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Orthotopic brain tumor models derived from glioblastoma stem-like cells, RNA sequencing in hematopoietic stem cells, Generation of inducible pluripotent stem cells from human dermal fibroblasts, In vitro preparation of dental pulp stem cell grafts combined with biocompatible scaffolds for tissue engineering, Gene expression knockdown in chronic myeloid leukemia stem cells, Identification and isolation of slow-cycling GSCs, Assessment of CD133, EpCAM, and much more.

  • Pharmacology and Toxicology of Cytochrome P450 - 60th Anniversary

    • 1st Edition
    • Volume 95
    • English
    Pharmacology and Toxicology of Cytochrome P450 - 60th Anniversary, Volume 95 highlights the extensive contributions by worldwide researchers in the cytochrome P450 (P450) field over the past six decades, and since the first article on P450 was published in 1962. Chapters in this new release include Multiple conformations of cytochromes P450 and the relevance to predicting SAR, Pharmacogenetics of the cytochromes P450 and relevance to drug metabolism, Cytochromes P450 drug metabolism within the brain, Mammalian cytochrome P450 biodiversity: Physiological importance, function, and protein and genomic structures of cytochromes P4502B in multiple species of woodrats with different dietary preferences, and more. Additional section cover Atypical kinetics of cytochrome P450 enzymes in drug metabolism, Biosynthesis using cytochrome P450 Enzymes: focus on synthesis of drug metabolites, Use of engineered cytochrome P450s for accelerating drug discovery and development, Assessing cytochrome P450 function using genetically engineered mouse models, Use of the biologicals with sustainable reproducibility for phenotyping study of cytochrome P450 enzymes involved in the biotransformation of test compounds and calculating the fraction unbound parameter, for anticipating drug Interactions, and much more. Research on many forms of P450s has been extended into different fields, from molecules to in vivo situations because pharmacologists and toxicologists appreciate and are attracted to the potential therapeutics. The purpose of this volume is to collect a comprehensive description of major progress to date, to discuss possible future directions, and to invite young researchers to join this important and exciting world of P450.

  • Parathyroid Hormone

    • 1st Edition
    • Volume 120
    • English
    Vitamins and Hormones serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Fish Roe

    Biochemistry, Products, and Safety
    • 1st Edition
    • Alaa El-Din A. (Aladin) Bekhit
    • English
    Provides comprehensive coverage of the components available in fish roe and highlights their biological and nutritional effects as well as their sensory and safety attributes. Fish Roe: Biochemistry, Products, and Safety describes various components available in fish roe and introduces their biological and nutritional effects. In addition to addressing biological and nutritional effects, this book also explores fish roe products and their safety while also providing coverage of the bioactives that are naturally available in fish roe or generated during processing, thereby outlining the maximum benefits that can be obtained from this natural resource. Beginning with the introduction of fish roe production procedures worldwide, this book further explores the processing of traditional fish roe products from Europe, Asia, and the Middle East, where fish roe is frequently consumed. This book also discusses the sensory and safety attributes of fish roe and will be a comprehensive reference for food scientists, chemists, food process engineers, developers, researchers, and students in the field of seafood science.

  • Application of Biofilms in Applied Microbiology

    • 1st Edition
    • Maulin P. Shah
    • English
    Application of Biofilms in Applied Microbiology gives a complete overview on the structure, physiology and application of biofilms produced by microbes, along with their potential application in biotechnology. Sections cover new technologies for biofilm study, physiology of microorganisms in biofilms, bacterial biofilms, biofilm development, and fungal biofilms, summarizing various technologies available for biofilm study. Subsequent chapters describe biofilm developments with Bacillus subtillis, Escherichia coli, and Pseudomonas putida, along with several chapters on the study of microbial biofilm and their advantages and disadvantages in the area of environmental biotechnology. The book closes with a chapter on the rapid development of new sequencing technologies and the use of metagenomics, thus revealing the great diversity of microbial life and enabling the emergence of a new perspective on population dynamics.

  • Targeted Nanomedicine for Breast Cancer Therapy

    • 1st Edition
    • Shivani Rai Paliwal + 1 more
    • English
    Targeted Nanomedicine for Breast Cancer Therapy provides a compilation of treatment approaches for breast cancer, including conventional receptor targeting methods and novel strategies like stimuli responsive methods and tumor micro-environment responsive strategies. This book compiles the most important information on the state-of-the-art therapeutics, including breast cancer biomarkers and design principles of bio-responsive nanosystems. Presented in two parts, sections cover basic and receptor mediated targeting approaches and examine tumor microenvironment mediated approaches. This is a useful book for pharmaceutical scientists and basic and clinical scientists working in the research area of breast cancer and drug discovery both from academics and industry.Worldwide, breast cancer is the most common cancer in women, however, breast cancer therapy is always challenging. This book aims to help researchers remain updated on the most targeted nanomedicine research available.

  • Early Nutrition and Long-Term Health

    Mechanisms, Consequences, and Opportunities
    • 2nd Edition
    • Jose M Saavedra + 1 more
    • English
    Early Nutrition and Long-Term Health: Mechanisms, Consequences, and Opportunities, Second Edition updates and expands upon the content in the first edition and adds focus on actionable and modifiable aspects of nutrition that have an impact on long-term health and disease. Part I examines the associations and the mechanisms of early life nutrition on growth as well as the development of cognitive, metabolic, immune, and dietary patterns and behaviors. Part II reviews the associations and impact of early life nutrition on non-communicable disease as well as their societal and economic impact. Part III focuses on the dietary and nutritional needs and approaches to optimizing the different stages of nutrition, from conception to the second year of life. Nutritionists, pediatricians, academics with research interest in this area, and food industry and healthcare professionals working in infant/child product and services, as well as students studying related disciplines, will benefit from this updated reference.

  • Autophagy and Metabolism

    Potential Target for Cancer Therapy
    • 1st Edition
    • Dhruv Kumar + 1 more
    • English
    Autophagy and Metabolism: Potential Target for Cancer Therapy presents updates on autophagy in cancer metabolism and how it can be used to develop new, more efficient treatments. Written by experts in the field, the book presents recent research and explains how to translate it to the clinical setting. Sections discuss tumor cell metabolism and autophagy as therapeutic targets, autophagy regulation in cancer, signaling pathways in metabolic dysregulation in solid tumors, metabolic stress and cell death pathways, and the role of the tumor microenvironment. In addition, topics cover combined targeting autophagy, metabolism for cancer therapy, and the autophagy effect on immune cell metabolism. This will be a valuable resource for researchers, oncologists, graduate students, and members of the biomedical field who are interested in learning more about the interaction between autophagy and cancer metabolism.

  • Role of Chitosan and Chitosan-Based Nanomaterials in Plant Sciences

    • 1st Edition
    • Santosh Kumar + 1 more
    • English
    Role of Chitosan and Chitosan-Based Nanomaterials in Plant Sciences explores the physiological, morphological, biochemical and molecular regulation of chitosan and chitosan-based nanoparticles in plants in normal conditions, as well as during different stresses, and their probable mechanism of operation in the tolerance mechanism. The book stimulates further research in the field of chitosan and will foster further interests for researchers, academicians and scientists worldwide. Nanotechnology is being used widely in all disciplines of science and technology, including plant sciences. Chitosan has widely been reported as a beneficial organic compound for the growth and developments of plants and it plays a protective role for the plants against abiotic and biotic stresses. Yet there are very few books available that deal exclusively with Chitosan and Chitosan based nanoparticles impacts on plants respectively.

  • Helicase Enzymes Part A

    • 1st Edition
    • Volume 672
    • English
    Methods in Enzymology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Storage of Cereal Grains and Their Products

    • 5th Edition
    • Kurt A. Rosentrater
    • English
    Storage of Grains and Their Products, Fifth Edition, presents the most authoritative reference on the principles and practices of storing and handling grains and their products. Divided into four main sections, the book covers the range of storage systems available in both the developed and developing world, the practicalities of the design and implementation of grain storage systems, looking in detail at handling, cleaning, drying, aeration, instrumentation amongst other topics, specific threats to stored grains, pulses, oils and pseudocereals from chemicals, rodents, insects and biosecurity, and the economics of grain storage, government regulations and future considerations. Professionals responsible for the storage and handling of grains will find this book a great resource, however, it will also be of interest to academic researchers and postgraduate students in both cereal science and food processing.

  • Advances in Agronomy

    • 1st Edition
    • Volume 175
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 175, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field. Each chapter is written by an international board of authors.

  • Advances in Applied Microbiology

    • 119th Edition
    • Geoffrey M. Gadd + 1 more
    • English
    Advances in Applied Microbiology, Volume 119 continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine

    • 1st Edition
    • Alok Pandya + 2 more
    • English
    Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine discusses recent advances in science and technology using nanoscale units that show the novel concept of combining nanotechnology with various research disciplines within both the biomedical and medicine fields. Self-assembly of molecules, macromolecules, and polymers is a fascinating strategy for the construction of various desired nanofabrication in chemistry, biology, and medicine for advanced applications. It has a number of advantages: (1) It is involving atomic-level modification of molecular structure using bond formation advanced techniques of synthetic chemistry. (2) It draws from the enormous wealth of examples in biology for the development of complex, functional structures. (3) It can incorporate biological structures directly as components in the final systems. (4) It requires that the target self-assembled structures be thermodynamically most stable with relatively defect-free and self-healing. In this book, we cover the various emerging self-assembled nanostructured objects including molecular machines, nano-cars molecular rotors, nanoparticles, nanosheets, nanotubes, nanowires, nano-flakes, nano-cubes, nano-disks, nanorings, DNA origami, transmembrane channels, and vesicles. These self-assembled materials are used for sensing, drug delivery, molecular recognition, tissue engineering energy generation, and molecular tuning.

  • Histopathology Atlas of Acute Radiation Syndrome and Delayed Effects in Rhesus Macaques

    Kidney, Lung, Heart, Intestine and Mesenteric Lymph Node
    • 1st Edition
    • George Parker
    • English
    Histopathology Atlas of Acute Radiation Syndrome and Delayed Effects in Rhesus Macaques: Kidney, Lung, Heart, Intestine and Mesenteric Lymph Node provides a thoroughly illustrated review of the tissue damage and reparative changes associated with standardized irradiation doses in rhesus macaques. In addition to time-sequenced, routinely stained histologic sections, the book presents results of numerous histochemical, immunohistochemical and chromogenic in-situ stains that provide insights into the pathogenesis of radiation-associated tissue injury and repair. This book is compiled and written by a board-certified veterinary pathologist with more than 40 years of experience in the interpretation of experimentally induced tissue alterations in laboratory animals. This is an important resource for researchers in the field of animal science radiation injury, including radiation oncologists and individuals involved in disaster preparedness related to accidental or deliberate radiation exposure in large populations.

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