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Advances in Microbial Physiology
- 1st Edition, Volume 81 - September 14, 2022
- Editors: Robert K. Poole, David J. Kelly
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 8 9 8 8 - 6
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 8 9 8 9 - 3
Advances in Microbial Physiology, Volume 81 highlights new advances in the field with this new release presenting interesting chapters written by an international board of author… Read more
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Request a sales quoteAdvances in Microbial Physiology, Volume 81 highlights new advances in the field with this new release presenting interesting chapters written by an international board of authors. Updates in this release include sections on Antibiotic tolerance, Lanthanides in bacterial proteins, Bacterial toxins and host-microbe interactions, and Nitric oxide.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in the Advances in Microbial Physiology series
- Includes chapters that cover topics such as Antibiotic tolerance and Lanthanides in bacterial proteins
Microbiologists, biochemists, biotechnologists, and those interested in physiology, microbial biochemistry and its applications
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter One: A perspective on the role of lanthanides in biology: Discovery, open questions and possible applications
- Abstract
- 1: Discovery and importance
- 2: Regulatory effects of Ln
- 3: Sensing, uptake, and storage of Ln
- 4: Open questions
- 5: Applications
- 6: Concluding remarks
- References
- Chapter Two: Antimicrobial tolerance and its role in the development of resistance: Lessons from enterococci
- Abstract
- 1: Introduction
- 2: Mechanisms of antimicrobial tolerance: An overview
- 3: The cell envelope stress response plays a critical role in antimicrobial tolerance in enterococci
- 4: The oxidative stress response and its role in antimicrobial tolerance
- 5: Induction of the starvation response can stimulate antimicrobial tolerance in enterococci
- 6: Efflux pumps are an effective mechanism of antimicrobial tolerance by restricting and removing antimicrobials compounds from the cell
- 7: Loss of the ClpP protease reduces killing by ribosomal-targeting antimicrobials in enterococci
- 8: Slow- and non-growing cells evade the killing activity of antimicrobials to achieve antimicrobial tolerance
- 9: Conclusions
- Acknowledgments
- References
- Chapter Three: Bacterial AB toxins and host–microbe interactions
- Abstract
- 1: Introduction
- 2: Structure and function of AB toxins
- 3: AB toxin neutralization
- 4: Applications of AB toxins
- 5: Concluding remarks
- Acknowledgements
- References
- Chapter Four: Recent developments in our understanding of the physiology and nitric oxide-resistance of Staphylococcus aureus
- Abstract
- 1: Introduction
- 2: Inorganic metabolism
- 3: Organic metabolism
- 4: Respiration versus fermentation
- 5: S. aureus nitric oxide resistance
- 6: Conclusions
- References
- No. of pages: 146
- Language: English
- Edition: 1
- Volume: 81
- Published: September 14, 2022
- Imprint: Academic Press
- Hardback ISBN: 9780323989886
- eBook ISBN: 9780323989893
RP
Robert K. Poole
Professor Robert K Poole is Emeritus Professor of Microbiology at the University of Sheffield, UK. He was previously West Riding Professor of Microbiology at Sheffield and until 1996 held a Personal Chair in Microbiology at King’s College London. During his long career, he has been awarded several research Fellowships, and taken sabbatical leave at the Australian National University, Kyoto University and Cornell University. His career-long interests have been in the areas of bacterial respiratory metabolism, metal-microbe interactions and bioactive small gas molecules. In particular, he has made notable contributions to bacterial terminal oxidases and resistance to nitric oxide with implications for bacterial pathogenesis. He co-discovered the flavohaemoglobin Hmp, now recognised as the preeminent mechanism of nitric oxide resistance in bacteria. He has served as Chairman of numerous research council grant committees, held research grants for over 40 years and published extensively (h-index, 2024 = 70). He served on several Institute review panels in the UK and overseas. He is a Fellow of the Royal Society of Chemistry and the Royal Society of Biology.
Affiliations and expertise
West Riding Professor of Microbiology, Department of Molecular Biology and Biotechnology, University of Sheffield, UKDK
David J. Kelly
Professor David Kelly is Emeritus Professor of Microbial Physiology at the University of Sheffield, UK. He has >35 years research expertise in bacterial physiology and biochemistry, membrane protein transport processes and bioenergetics, and has worked with the zoonotic food-borne pathogen Campylobacter jejuni for >25 years. A major program to study C. jejuni physiology was carried out in his laboratory, in particular the responses to oxygen, many aspects of carbon metabolism and functional analysis of the electron transport chains. He has long-standing interests in membrane transport mechanisms and in the 1990s discovered an entirely new class of periplasmic binding-protein dependent prokaryotic solute transporters, the TRAP transporters, now known to be common in a diverse range of bacteria and archaea. He has published >150 papers (h-index 2024 = 56), held numerous grants, served on grant committees and has been a regular invited speaker at national and international conferences. He is the recipient of a Leverhulme Emeritus Fellowship from the Leverhulme Trust, UK.
Affiliations and expertise
Professor of Microbiology, Department of Molecular Biology and Biotechnology, University of Sheffield, UKRead Advances in Microbial Physiology on ScienceDirect