
Inflammation and Obesity
A New and Novel Approach to Manage Obesity and its Consequences
- 1st Edition - September 24, 2022
- Editor: Raman Mehrzad
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 0 9 6 0 - 0
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 0 9 6 1 - 7
Inflammation and Obesity: A New and Novel Approach to Manage Obesity and its Consequences is a comprehensive and up-to-date exploration of the correlation between obesity and in… Read more

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Request a sales quoteInflammation and Obesity: A New and Novel Approach to Manage Obesity and its Consequences is a comprehensive and up-to-date exploration of the correlation between obesity and inflammation. From the pathophysiology of obesity and inflammation, to the molecular mechanisms of obesity induced chronic inflammation, the book discusses how obesity and inflammation interact with other diseases. It highlights the hidden risk factors of obesity induced chronic inflammation, provides specific patient management guidelines regarding the higher inflammatory response in patients, and concludes with new therapeutic strategies to address inflammation in obese patients.
- Identifies the hidden physiological changes that accompany obesity, while also highlighting the challenge of managing obesity with a higher inflammatory response
- Discusses major hidden health risks of inflammation that accompany obesity, as well as management guidelines for obese patients
- Links the pathophysiology of inflammation and obesity to the therapeutic strategies that minimizes risk factors, thus opening new areas of research
Physicians in the field of general surgery, plastic surgery, internal medicine, primary care, endocrinology, rheumatology, obesity medicine, cardiology, gastroenterology, neurology, nutritionists. PhD-students focusing on metabolism, obesity research (huge market) and oncology research in different areas are also primary target markets. Doctors of acupuncture, naturopaths, chiropractors that deal with inflammation and obesity are also a primary target market.
Medical students, nurse practitioner and physician assistants in primary care, medical interns, medical residents, medical fellows
Medical students, nurse practitioner and physician assistants in primary care, medical interns, medical residents, medical fellows
- Cover
- Title page
- Table of Contents
- Copyright
- Dedication
- Contributors
- Chapter 1: Introduction to obesity and inflammation
- References
- Chapter 2: The obesity pandemic: How we are failing our patients
- Abstract
- Obesity as a disease
- Epidemiology
- Global impact of obesity
- Impact of increased incidence of obesity
- Origins of the obesity epidemic
- Sociodemographic factors associated with obesity [18]
- Behavioral factors associated with obesity
- Obesity and disease
- Type 2 diabetes
- Failures in management of obesity
- References
- Chapter 3: Inflammation: A multifaceted and omnipresent phenomenon
- Abstract
- Inflammation
- Allostasis and allostatic load
- Inflammation triggers
- Obesity
- Physical activity
- Dysbiosis
- Diet
- Chronic stress
- Disturbed sleep
- Chronic infections
- Xenobiotics
- References
- Chapter 4: Pathophysiology of obesity
- Abstract
- Structure of adipose tissue
- Phenotype of obesity
- Endocrine action of adipocytes in lean and obese states
- Putting it together: Treatment for obesity and metabolic syndrome
- Conclusion
- References
- Chapter 5: Consequences of inflammation in obesity
- Abstract
- Introduction
- Mechanism of inflammation
- Inflammatory processes in cardiovascular diseases and its relation to obesity
- Inflammatory processes in endocrine diseases and its relation to obesity
- Inflammatory processes in gastrointestinal diseases and its relation to obesity
- Inflammatory processes in musculoskeletal diseases and its relation to obesity
- Inflammatory processes in the central nervous system and their relation to obesity
- Conclusion
- References
- Chapter 6: Inflammation and obesity
- Abstract
- Obesity and inflammation
- Changes in adipose tissue
- Adipokines: Origins and effects
- Tumor necrosis factor alpha
- Interleukin 6
- Adiponectin
- Promotion of inflammation in obesity
- Insulin resistance
- microRNA
- Endothelial and microvascular dysfunction
- Obesity, inflammation, and cancer
- References
- Chapter 7: Obesity, inflammation, and aging
- Abstract
- Inflammation and aging
- Inflammation and obesity
- Connecting inflammation, obesity, and aging
- Antiinflammatory intervention for aging-related illnesses
- Conclusions
- References
- Chapter 8: Obesity, inflammation, and diseases of the gastrointestinal tract
- Abstract
- Introduction and epidemiology
- Obesity incidence in certain groups
- Etiology
- The connection between obesity and inflammation
- Obesity and gastrointestinal diseases
- Interventions
- References
- Chapter 9: Obesity, inflammation, and cardiovascular disorders
- Abstract
- Introduction
- Atherosclerosis and coronary artery disease
- Heart failure
- Arrhythmias
- Aortic stenosis
- Aneurysmal disease
- The obesity paradox
- References
- Chapter 10: Obesity, inflammation, and CNS disorders
- Abstract
- Introduction
- CNS disorders associated with obesity
- Conclusions
- References
- Chapter 11: Obesity, inflammation and muscle weakness
- Abstract
- Introduction
- Obesity and relative muscle weakness
- Sarcopenic obesity
- Summary and conclusions
- References
- Chapter 12: Resolution of inflammation
- Abstract
- Resolution of inflammation
- Cyclopentenone prostaglandins
- Apoptotic cells and their clearance
- microRNA
- Resolution-directed lipid mediators of inflammation
- Lipoxins
- Resolvins
- Maresins
- Protectins
- References
- Chapter 13: Physical activity in obesity and inflammation prevention and management
- Abstract
- Introduction
- Obesity-related inflammation
- Physical activity and obesity-related inflammation
- Weight loss and maintenance
- Conclusion
- References
- Chapter 14: Diet and inflammation in obesity: Prevention and management
- Abstract
- The obesity epidemic
- Pathophysiology of obesity
- Leptin and inflammation
- Obesity and markers of inflammation—Are they adequate?
- Diet and obesity
- Sugar and obesity
- Sugar and inflammation
- High fat
- Essential fatty acids
- Saturated and unsaturated fat
- Trans fats
- What is an antiinflammatory diet
- Antiinflammatory diet and weight loss
- Antiinflammatory benefits of popular diets
- The long-term outlook
- References
- Chapter 15: Management of obesity and related inflammatory disorders
- Abstract
- Introduction
- Behavioral weight management strategies and inflammation
- The role of the microbiome in treatment of obesity and inflammation
- Role of weight loss medications
- Bariatric interventions endoscopic/surgical and inflammation
- A standardized evaluation of inflammation in patients with obesity
- A stepwise approach for managing inflammation and weight in the obese patients
- References
- Chapter 16: New therapeutic strategies in the management of obesity-modulated inflammation
- Abstract
- Staging obesity-related inflammation
- Glucose-insulin homeostasis biomarkers
- Adipose tissue biomarkers
- Inflammatory biomarkers
- Omic-based biomarkers
- The microbiome and obesity
- Alternative treatments for obesity
- Artificial intelligence and management of obesity
- Botanicals in the treatment of obesity and obesity-related inflammation
- Sleep and obesity
- References
- Index
- No. of pages: 296
- Language: English
- Edition: 1
- Published: September 24, 2022
- Imprint: Academic Press
- Paperback ISBN: 9780323909600
- eBook ISBN: 9780323909617
RM
Raman Mehrzad
Dr. Mehrzad is a physician, scientist and author who has worked closely with attendings and hundreds of students, interns, residents and fellows throughout his career. He is American Board Certified in Internal medicine and worked as a specialized physician at Yale New Haven Hospital for 3 years where he was also a clinical instructor at Yale School of Medicine. Currently, he is pursuing a Plastic & Reconstructive Surgery residency at Rhode Island Hospital, Brown University and hence with his background brings both medical and surgical knowledge to the project. Dr. Mehrzad has conducted extensive scientific research in multiple areas in medicine, surgery and education and has over 36 peer-reviewed articles and over 22 abstracts published. He has written 5 books that are selling widely in Sweden, Denmark, Austria, Germany and Switzerland, and contributed to six 6 medical and surgical textbooks. He is also an international lecturer and has lectured at over 100 schools for thousands of students across Europe. Lastly, beside his medical degree, Dr. Mehrzad holds an Executive Master of Healthcare Leadership degree from Brown University and a Master of Business Administration degree from University of Massachusetts, Isenberg school of Business.
Affiliations and expertise
Division of Plastic and Reconstructive Surgery, Rhode Island Hospital, The Warren Alpert School of Brown University, Providence, RI, United StatesRead Inflammation and Obesity on ScienceDirect