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Elsevier

Books in Life sciences

  • Genetic Engineering of Horticultural Crops

    • 1st Edition
    • Gyana Ranjan Rout + 1 more
    • English
    Genetic Engineering of Horticultural Crops provides key insights into commercialized crops, their improved productivity, disease and pest resistance, and enhanced nutritional or medicinal benefits. It includes insights into key technologies, such as marker traits identification and genetic traits transfer for increased productivity, examining the latest transgenic advances in a variety of crops and providing foundational information that can be applied to new areas of study. As modern biotechnology has helped to increase crop productivity by introducing novel gene(s) with high quality disease resistance and increased drought tolerance, this is an ideal resource for researchers and industry professionals.

  • Methods in Extracellular Matrix Biology

    • 1st Edition
    • Volume 143
    • English
    Methods in Extra Cellular Matrix, Volume 142, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are sections devoted to Elastin, Quantification of collagen and elastin, Fibrillins, Lysyl oxidase, Fibulins, Matrilins, Hyaluronic Acid, Small leucine-rich proteoglycans, Syndecans, Fibronectin, SPARC, Thrombospondins, Tenascins, Collagen IV, Multi-photon analysis of ECM, Cell-derived extracellular matrices, Laminins, Fibrillar Collagens, Imaging ECM in developing embryos, Analysis of Matrix Degradation, Ultrastructural analysis of ECM, Versican and Large proteoglycans, and an ECM crosslink analysis. This series covers a wide array of topics about the extracellular matrix, including an understanding of crucial proteins and glycoproteins components of ECM.

  • Neuromodulation

    Comprehensive Textbook of Principles, Technologies, and Therapies
    • 2nd Edition
    • Elliot Krames + 2 more
    • English
    Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies, Second Edition, serves as a comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. Since the publication of the first edition seven years ago, there has been an explosion of knowledge in neuromodulation, optogenetics, bioelectronics medicine and brain computer interfacing. Users will find unique discussions of the fundamental principles of neuromodulation and therapies, and how they are applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs. The book focuses on comprehensive coverage of spinal cord stimulation, non-interventional and interventional brain stimulation, peripheral nerve stimulation, and the emerging fields of neuromodulation, including optogenetics and bioelectronics medicine.

  • Metastatic Disease of the Nervous System

    • 1st Edition
    • Volume 149
    • David Schiff + 1 more
    • English
    Metastatic Disease of the Nervous System, Volume 149, begins with an overview of the impact and range of direct neoplastic involvement of the central and peripheral nervous system, comprehensively reviewing all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy in their management, and the complications of these interventions. The clinical manifestations, diagnosis and treatment of leptomeningeal, dural, spinal epidural and plexus metastases are also covered in detail.

  • Handbook of Developmental Neurotoxicology

    • 2nd Edition
    • William Slikker Jr. + 2 more
    • English
    Handbook of Developmental Neurotoxicology, Second Edition, provides a comprehensive view of the fundamental aspects of neurodevelopment, the pathways and agents that affect them, relevant clinical syndromes, and risk assessment procedures for developmental neurotoxicants. The editors and chapter authors are internationally recognized experts whose collaboration heralds a remarkable advance in the field, bridging developmental neuroscience with the principles of neurotoxicology. The book features eight new chapters with newly recruited authors, making it an essential text for students and professionals in toxicology, neurotoxicology, developmental biology, pharmacology, and neuroscience.

  • Myogenesis in Development and Disease

    • 1st Edition
    • Volume 126
    • English
    Myogenesis in Development and Disease, Volume 126, the latest volume in the Current Topics in Developmental Biology series, covers major topics of research in myogenesis, with a particular emphasis on regeneration and muscle disease. It includes contributions from an international board of authors, providing a comprehensive set of reviews.

  • Sustainable Food Systems from Agriculture to Industry

    Improving Production and Processing
    • 1st Edition
    • Charis M. Galanakis
    • English
    Sustainable Food Systems from Agriculture to Industry: Improving Production and Processing addresses the principle that food supply needs of the present must be met without compromising the ability of future generations to meet their needs. Responding to sustainability goals requires maximum utilization of all raw materials produced and integration of activities throughout all production-to-consum... stages. This book covers production stage activities to reduce postharvest losses and increase use of by-products streams (waste), food manufacturing and beyond, presenting insights to ensure energy, water and other resources are used efficiently and environmental impacts are minimized. The book presents the latest research and advancements in efficient, cost-effective, and environmentally friendly food production and ways they can be implemented within the food industry. Filling the knowledge gap between understanding and applying these advancements, this team of expert authors from around the globe offer both academic and industry perspectives and a real-world view of the challenges and potential solutions that exist for feeding the world in the future. The book will guide industry professionals and researchers in ways to improve the efficiency and sustainability of food systems.

  • Gut Microbiota

    Interactive Effects on Nutrition and Health
    • 1st Edition
    • Edward Ishiguro + 2 more
    • English
    Gut Microbiota: Interactive Effects on Nutrition and Health focuses on the fascinating intestinal microbiome as it relates to nutrition. The book covers the core science in the microbiome field and draws links between the microbiome and nutrition in medicine. Reflecting the most current state of evidence available in the field, the early chapters introduce key concepts about the microbiome, and the latter focus on the application of the gut microbiome and nutrition science. Both human studies and animal studies (where appropriate) are discussed throughout the work. Addressing topics such as gut microbiota throughout the lifespan, gut microbiota in health and disease, and genetic and environmental influences on gut microbiota, this book will provide scientists and clinicians who have an interest in the microbiome with an understanding of the future potential and limitations of this tool as they strive to make use of evidence-based diet information for the maintenance of good health.

  • Food Neophobia

    Behavioral and Biological Influences
    • 1st Edition
    • Steve Reilly
    • English
    Food Neophobia: Behavioral and Biological Influences brings together academic and applied studies to give a comprehensive overview of this topic in both sensory and consumer science and pediatric psychology. The effects of food neophobia can have a huge impact on children’s lives and an influence across their lifespan. Split into two main sections, the book focuses on both the environmental and biological aspects of food neophobia. It covers social, contextual and psychosocial factors that affect food neophobia. Sensory aspects of food neophobia are covered with chapters on disgust and sensation seeking, and genetic and evolutionary influences are also thoroughly discussed. The book is essential reading for academic researchers studying food neophobia from a sensory, consumer science and psychological perspective. It will also be of value to food product developers, especially those working on products for children. Finally, healthcare professionals treating patients suffering from food neophobia will be able to gain greater insight into this condition.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 83
    • English
    Advances in Clinical Chemistry, Volume 83, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest, most up-to-date technologies related to the field of clinical chemistry, with this release presenting comprehensive updates on Urinary Nucleosides and Deoxynucleosides, Locked Nucleic Acid Technology for Highly Sensitive Detection of Somatic Mutations in Cancer, Liquid Biopsy: From Basic Research to Clinical Practice, Circulating Tumor Cells and Implications of the Epithelial-to-Mesenc... Transition, and more.

  • Transcriptional Gene Regulation in Health and Disease

    • 1st Edition
    • Volume 335
    • English
    Transcriptional Gene Regulation in Health and Disease, Volume 335, the latest release in the International Review of Cell and Molecular Biology reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. The articles published in IRCMB have a high impact and an average cited half-life of nine years. This great resource ranks high amongst scientific journals dealing with cell biology.

  • Handbook of Immunoassay Technologies

    Approaches, Performances, and Applications
    • 1st Edition
    • Sandeep K. Vashist + 1 more
    • English
    Handbook of Immunoassay Technologies: Approaches, Performances, and Applications unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays, to the smartphone-based point-of-care formats. The advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies equipped with personalized mobile healthcare tools are paving the way to next-generation immunoassays, and are all discussed in this comprehensive text. Immunoassays play a prominent role in clinical diagnostics as they are the eyes of healthcare professionals, helping them make informed clinical decisions via confirmed disease diagnosis, and thus enabling favorable health outcomes. The faster and reliable diagnosis of infections will further control their spread to uninfected persons. Similarly, immunoassays play a prominent role in veterinary diagnostics, food analysis, environmental monitoring, defense and security, and other bioanalytical settings. Therefore, they enable the detection of a plethora of analytes, which includes disease biomarkers, pathogens, drug impurities, environmental contaminants, allergens, food adulterants, drugs of abuse and various biomolecules.

  • Methods in Consumer Research, Volume 2

    Alternative Approaches and Special Applications
    • 1st Edition
    • Gaston Ares + 1 more
    • English
    Methods for Consumer Research, Volume Two: Alternative Approaches and Special Applications brings together world leading experts in global consumer research who provide a fully comprehensive state-of-the-art coverage of emerging methodologies and their innovative application. The book puts consumer research in-context with coverage of immersive techniques and virtual reality, while also looking at health-related Issues in consumer science, including sections on food intake and satiation. Other sections delve into physiological measurements within the context of consumer research and how to design studies for specific populations. In conjunction with the first volume, which covers new approaches to classical methodology, this book is an invaluable reference for academics working in the fields of in-sensory and consumer science, psychology, marketing and nutrition. With examples of the methodology being applied throughout, it serves as a practical guide to research and development managers in both food and non-food companies.

  • Forensic Odontology

    Principles and Practice
    • 1st Edition
    • Thomas J. David + 1 more
    • English
    Forensic Odontology: Principles and Practice details the aspects necessary to become an accomplished forensic odontologist, including an illustration of the skills necessary to become an expert witness. The book is ideal for both the experienced and novice forensic odontologist, covering many fields of expertise, including civil and criminal matters. The civil side involves standard of care and personal injury matters, while the criminal side involves not only dental identification, but management of mass fatality incidents, age assessment, child and elder abuse, and bitemark analysis.

  • Biosynthesis & Integration of Cell Metabolism

    • 1st Edition
    • B C Currell + 1 more
    • English
    Biotechnology by Open Learning: Biosynthesis and the Integration of Cell Metabolism focuses on the structure and activities of cells, including nitrogen fixation, biosynthesis, and metabolic pathways. The manuscript takes a look at precursor molecules for biosynthesis, uptake of nutrients, and nitrogen and sulfur assimilation. Discussions focus on the importance of nitrogen fixation in nature, assimilation of sulfate, ammonia, nitrate, and molecular nitrogen, passive diffusion through protein channels, nutritional requirements of cells, and membranes as permeability barriers. The book then explores amino acid and nucleotide biosynthesis and biosynthesis of lipids. Topics include commercial importance of polysaccharides of micro-organisms, biosynthesis of disaccharides, oligosaccharides and polysaccharides, occurrence of carbohydrates in living systems, and metabolic links between amino acid biosynthesis and the biosynthesis of purines and pyrimidines. The text examines the integration and regulation of metabolism and control of metabolic pathway flux, including patterns of regulation of metabolic pathways, coupling agents in metabolism, integration and regulation of metabolism, and maintenance of metabolic homeostasis through energy coupling. The manuscript is a valuable source of data for biotechnologists and researchers interested in biosynthesis and integration of cell metabolism.

  • Sixth International Congress of Neurology

    Brussels, 21–28 July 1957
    • 1st Edition
    • L. van Bogaert + 1 more
    • English
    Neurology, Volume 1 presents the proceedings of the First International Congress of Neurological Sciences, held in Brussels, Belgium, on July 21–28, 1957. This book provides information pertinent to the fundamental aspects of neurology. Organized into 107 chapters, this compilation of papers begins with an overview of the significance of genetic factors in multiple sclerosis wherein its occurrence in more than one member of a family have a very limited value. This text then examines the two common disorders, namely, cervical spondylosis and disseminated sclerosis. Other chapters explain the mechanism of demyelination problem in considering the pathology of multiple sclerosis or any of the degenerative diseases of the nervous system. This book discusses as well the commonest types of headaches observed, including tension headache, migraine headache, post-traumatic headache, and those associated with hypertension. The final chapter deals with cerebellar ataxia, chronic respiratory infection, and telangiectasia. This book is a valuable resource for neurologists, psychiatrists, and neuropsychiatrists.

  • The Pharmacological and Epidemiological Aspects of Adolescent Drug Dependence

    Proceedings of the Society for the Study of Addiction, London, 1 and 2 September 1966
    • 1st Edition
    • C. W. M. Wilson
    • English
    The Pharmacological and Epidemiological Aspects of Adolescent Drug Dependence is a collection of proceedings presented at the International Symposium on the Pharmacological and Epidemiological Aspects of Adolescent Drug Dependence, held in London on September 1-2, 1966 under the auspices of the Society for the Study of Addiction to Alcohol and Other Drugs. The symposium provided a forum for discussing the pharmacological and epidemiological aspects of drug dependence in adolescents. Comprised of 10 chapters, this volume begins with an overview of the chemistry and pharmacology of narcotic drugs in adolescence, as well as narcotic addiction in young people in the United States. The discussion then turns to pharmacology and clinical observations on stimulant drugs and hallucinogenic drugs; the epidemiology and social pharmacology of drugs of dependence; and features of adolescent drug dependence. Regulations aimed at controlling drugs of dependence are also analyzed in relation to the national incidence of adolescent dependence in certain countries such as Britain, Belgium, Israel, and the Netherlands. The remaining chapters focus on the language, evidence, and patterns of drug abuse, together with research in relation to drugs of dependence. This book will be of interest to pharmacologists, epidemiologists, and policymakers concerned with drug dependence.

  • Netter's Neurology

    • 3rd Edition
    • Jayashri Srinivasan + 3 more
    • English
    Perfect for residents, medical students, generalists, nurses, and other healthcare professionals who need a practical, working knowledge of neurology, Netter's Neurology, 3rd Edition, provides a concise overview highlighted by unique, memorable Netter illustrations. This award-winning visual resource showcases the well-known work of Frank H. Netter, MD, and his successor, Carlos Machado, MD, a physician who has created clear, full-color illustrations in the Netter tradition.

  • Vitamin D

    Volume 1: Biochemistry, Physiology and Diagnostics
    • 4th Edition
    • Martin Hewison + 3 more
    • English
    Vitamin D: Volume One: Biochemistry, Physiology and Diagnostics, Fourth Edition, presents the latest information from international experts in endocrinology, bone biology and human physiology, taking readers through the basic research of vitamin D. This impressive reference presents a comprehensive review of the multifaceted vitamin D. Researchers from all areas will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted genomic and proteomic insights on the mechanisms of disease.

  • Vitamin D

    Volume 2: Health, Disease and Therapeutics
    • 4th Edition
    • Martin Hewison + 3 more
    • English
    Vitamin D: Volume 2: Health, Disease and Therapeutics, Fourth Edition, authoritatively covers the evidence for new roles for vitamin D, ranging from cardiovascular disease, to cancer, diabetes, inflammatory bowel disease, multiple sclerosis and renal disease. This collection represents a who’s who of vitamin D research and the coverage is appropriately broad, drawing in internal medicine, orthopedics, oncology and immunology. Clinical researchers will gain a strong understanding of the molecular basis for a particular area of focus.

  • Bladder Cancer

    • 1st Edition
    • Ja Hyeon Ku
    • English
    Bladder Cancer is designed for researchers and clinicians involved in urologic practice, including urologists, medical oncologists, pathologists and radiologists. It provides comprehensive guidance for treating and understanding bladder cancer and serves as an up-to-date reference reflecting evidence-based research. The biological behavior of this disease entity shows a heterogeneous pattern with diverse morbidity and mortality depending on a variety of factors, such as tumor characteristics (tumor stage, grade, size, number, shape, and histologic subtypes) and applied treatment modalities (surgery or non-surgical management). This book presents the substantial academic developments in the field of bladder cancer in one convenient reference.

  • The Rat Brain in Stereotaxic Coordinates: Compact

    • 7th Edition
    • George Paxinos + 1 more
    • English
    The Rat Brain in Stereotaxic Coordinates Compact, Seventh Edition is a smaller sized (8.5 x 11inch), abridged version of the most referenced work in neuroscience (over 35,000 citations). The compact edition provides the coronal plates and diagrams of the current seventh edition in a smaller, more convenient spiral format and at a student friendly price. This book includes an introduction on current concepts in neuroanatomy, such as neuromeres and brain development. Students and seasoned researchers will find the first major unified nomenclature ontology tree based on development that features coronal photographic plates and juxtaposed diagrams.

  • Boorman's Pathology of the Rat

    Reference and Atlas
    • 2nd Edition
    • Andrew W. Suttie + 6 more
    • English
    Boorman’s Pathology of the Rat: Reference and Atlas, Second Edition, continues its history as the most comprehensive pathology reference on rat strains for researchers across science and medicine using rat models in the laboratory. It offers readers an added emphasis on the Sprague-Dawley and Wistar rat strains that is consistent with current research across academia, government, and industry. In addition, the book provides standard diagnostic criteria, basic content on histology, histological changes that result from drug toxicity and neoplasm, pathology terminology, and four-color photographs from the NTP archive and database. With updated references and photographs, as well as coverage of all rat strains, this book is not only the standard in the field, but also an invaluable resource for toxicologists, biologists, and other scientists engaged in regulatory toxicology who must make the transition from pathology results to the promulgation of meaningful regulations.

  • Die Design for Extrusion of Plastic Tubes and Pipes

    • 1st Edition
    • Sushil Kainth
    • English
    This book is a step-by-step guide to die design for tubes and pipes. It offers unique coverage of the topic from a highly practical perspective. Written for plastics processing and design engineers, technical and manufacturing managers, die designers and manufacturers. This comprehensive guide includes worked examples to illustrate problem solving and detailed drawings of complete dies for various applications. It covers mono- and multilayers pipes, as well as important melt flow variables (e.g., pressure drop, shear stress, shear rate, temperature variations, distribution variations) of key materials determined using FEM software.

  • Comprehensive Toxicology

    • 3rd Edition
    • Charlene McQueen
    • English
    Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology.

  • Personalized Predictive Modeling in Type 1 Diabetes

    • 1st Edition
    • Eleni I. Georga + 2 more
    • English
    Personalized Predictive Modeling in Diabetes features state-of-the-art methodologies and algorithmic approaches which have been applied to predictive modeling of glucose concentration, ranging from simple autoregressive models of the CGM time series to multivariate nonlinear regression techniques of machine learning. Developments in the field have been analyzed with respect to: (i) feature set (univariate or multivariate), (ii) regression technique (linear or non-linear), (iii) learning mechanism (batch or sequential), (iv) development and testing procedure and (v) scaling properties. In addition, simulation models of meal-derived glucose absorption and insulin dynamics and kinetics are covered, as an integral part of glucose predictive models. This book will help engineers and clinicians to: select a regression technique which can capture both linear and non-linear dynamics in glucose metabolism in diabetes, and which exhibits good generalization performance under stationary and non-stationary conditions; ensure the scalability of the optimization algorithm (learning mechanism) with respect to the size of the dataset, provided that multiple days of patient monitoring are needed to obtain a reliable predictive model; select a features set which efficiently represents both spatial and temporal dependencies between the input variables and the glucose concentration; select simulation models of subcutaneous insulin absorption and meal absorption; identify an appropriate validation procedure, and identify realistic performance measures.

  • Advances in Agricultural Animal Welfare

    Science and Practice
    • 1st Edition
    • Joy Mench
    • English
    Advances in Agricultural Animal Welfare fully explores developments in the key areas of agricultural animal welfare assessment and improvement. Analyzing current topical issues, as well as reviewing the historical welfare issues, the volume is a comprehensive review of the field. Divided into five sections, the book opens in Part One by reviewing advances in animal welfare science, examining cognitive psychology, genetics and genomics. Part Two then looks at transdisciplinary research in animal welfare, with coverage of bioethics, welfare and sustainability from both environmental and food safety perspectives. Part Three explores the process of translating science into policy and practice, followed by discussion on the global achievability of welfare standards in Part Four. Finally, Part Five highlights some emerging issues in agricultural animal welfare. This book is an essential part of the wider ranging series Advances in Farm Animal Welfare, with coverage of cattle, sheep, pigs, poultry and aquaculture. With its expert editor and international team of contributors, Advances in Agricultural Animal Welfare is a key reference tool for welfare research scientists and students, practicing vets involved in welfare assessment, and indeed anyone with a professional interest in the welfare of agricultural animals.

  • Cheetahs: Biology and Conservation

    Biodiversity of the World: Conservation from Genes to Landscapes
    • 1st Edition
    • English
    Cheetahs: Biology and Conservation reports on the science and conservation of the cheetah. This volume demonstrates the interdisciplinary nature of research and conservation efforts to study and protect the cheetah. The book begins with chapters on the evolution, genetics, physiology, ecology and behavior of the species, as well as distribution reports from range countries. These introductory chapters lead into discussions of the challenges facing cheetah survival, including habitat loss, declining prey base, human-wildlife conflict, illegal trade, and newly-emerging threats, notably climate change. This book also focuses on conservation strategies and solutions, including environmental education and alternative livelihoods. Chapters on the role of captive cheetahs to conservation and the long-term research of the species are included, as are a brief discussion of the methods and analyses used to study the cheetah. The book concludes with the conservation status and future outlook of the species. Cheetahs: Biology and Conservation is a valuable resource for the regional and global communities of cheetah conservationists, researchers, and academics. Although cheetah focussed the book provides information relevant to the study of broader topics such as wildlife conservation, captive breeding, habitat management, conservation biology and animal behaviour. Cover photograph by Angela Scott

  • Advances in Cattle Welfare

    • 1st Edition
    • Cassandra Tucker
    • English
    Advances in Cattle Welfare provides a targeted overview of contemporary issues in dairy and beef cattle welfare. The volume addresses welfare-related topics in both research and on-farm applications. Opening with an introduction to cattle production systems, the book covers the three major areas of cattle welfare; on-farm welfare assessment, behavioral priorities of cattle and novel perspectives on specific aspects of management. Chapters examine the key issues within each area, including such topics as the goals and measures included in welfare assessments, the importance to cattle of access to pasture and engaging in social behavior, human-animal interactions, painful procedures, and disease and metabolic challenge. This book is an essential part of the wider ranging series Advances in Farm Animal Welfare, with coverage of cattle, sheep and pigs. With its expert editor and international team of contributors, Advances in Cattle Welfare is a key reference tool for welfare research scientists and students, veterinarians involved in welfare assessment, and indeed anyone with a professional interest in the welfare of cattle.

  • Encyclopedia of Cardiovascular Research and Medicine

    • 1st Edition
    • Volume 4
    • Douglas B. Sawyer + 1 more
    • English
    Encyclopedia of Cardiovascular Research and Medicine, Four Volume Set offers researchers over 200 articles covering every aspect of cardiovascular research and medicine, including fully annotated figures, abundant color illustrations and links to supplementary datasets and references. With contributions from top experts in the field, this book is the most reputable and easily searchable resource of cardiovascular-focus... basic and translational content for students, researchers, clinicians and teaching faculty across the biomedical and medical sciences. The panel of authors chosen from an international board of leading scholars renders the text trustworthy, contemporary and representative of the global scientific expertise in these domains. The book's thematic structuring of sections and in-depth breakdown of topics encourages user-friendly, easily searchable chapters. Cross-references to related articles and links to further reading and references will further guide readers to a full understanding of the topics under discussion. Readers will find an unparalleled, one-stop resource exploring all major aspects of cardiovascular research and medicine.

  • Encyclopedia of Marine Mammals

    • 3rd Edition
    • Bernd Würsig + 2 more
    • English
    The Encyclopedia of Marine Mammals, Third Edition covers the ecology, behavior, conservation, evolution, form and function of whales, dolphins, seals, sea lions, manatees, dugongs, otters and polar bears. This edition provides new content on anthropogenic concerns, latest information on emerging threats such as ocean noise, and impacts of climate change. With authors and editors who are world experts, this new edition is a critical resource for all who are interested in marine mammals, especially upper level undergraduate and graduate students, researchers, and managers, and is a top reference for those in related fields, from oceanographers to environmental scientists.

  • Hepatitis C in Developing Countries

    Current and Future Challenges
    • 1st Edition
    • Sanaa M. Kamal
    • English
    Hepatitis C in Developing Countries: Current and Future Challenges explores the current state of HCV in several countries, including Africa, Asia and South America. It maintains a dedicated focus on the epidemiology, clinical patterns, virologic diversity, coinfections, natural history and progression, complications, and response to standard of care (SOC) pegylated interferon and ribavirin therapy of HCV with recommendations specific to middle and low income countries. Readers will find detailed information on the burden of HCV infection from a global health and economic perspective, along with data from multicenter trials on DAAs that have enrolled patients infected with HCV non-genotype 1.

  • Neurofeedback

    Tools, Methods and Applications
    • 1st Edition
    • Pascale Vincent
    • English
    The artificial intelligence of robots capable of learning from their errors and modifying their behavior accordingly is modeled on the activity of neurons in the brain.Emotional stress, traffic accidents, bereavement; these are all factors that can disrupt this neural activity, sometimes to the point of generating suffering that can be difficult to relieve. Neurofeedback, derived from neuroscience, is a computerized technique for training and re-balancing the brain’s electrical activity using neuroplasticity, which allows the brain to self-correct and regain a stable equilibrium, thus promoting recovery from traumas and a return to well-being. Neurofeedback: Tools, Methods and Applications deals with neurofeedback, explaining the functioning of the tool, its action on the equilibration of neural activity, and the differences between classical and dynamic systems. The results of the author's research and observations, the applications of these two tools, and the effects produced on the patients are explored, along with testimonies that describe and explain concepts in detail.Different neurofeedback tools are presented in this book, together with their function and explicit specificities adapted to the needs of each user. Their applications to psychological and cognitive disorders make neurofeedback an efficient and promising neurotherapy technique.

  • Temporal Sampling and Representation Updating

    • 1st Edition
    • Volume 236
    • English
    Temporal Sampling and Representation Updating, Volume 236, addresses the gap between laboratory studies using static or predictable stimuli and the more complex change that is a characteristic of the real world. Topics in this new volume include a section on Unfolding the time course of emotion perception, Temporal sampling and representation updating for action in interception and grasping tasks, The influence of Cognitive Control and Attention on Temporal Sampling: Lessons from the Attentional Blink, Synchronizing tracking eye movements with the motion of a visual target, and Sampling feature distributions with visual search in heterogeneous displays.

  • The Human Microbiome

    • 1st Edition
    • Volume 44
    • English
    Methods in Microbiology, Volume 44 presents the latest volume in the most prestigious series devoted to techniques and methodology in the field, with updated chapters that cover Metabolomics and the vaginal microbial ecosystem and health, Esophageal microbiome, Bioinformatics methods, Evolution of biomolecules, genomes and communities, and Gut microbial metabolism or the acquisition of the gut microbiome. Established for over 30 years, this comprehensive series provides ready-to-use recipes, the latest emerging techniques, and novel approaches on tried, tested and established methods.

  • Risk Management of Complex Inorganic Materials

    A Practical Guide
    • 1st Edition
    • Violaine Verougstraete
    • English
    Risk Management of Complex Inorganic Materials: A Practical Guide facilitates the risk assessment and management of complex inorganic materials around the world by providing accessible and specific guidance on their assessment. Inorganic complex materials, such as ores and concentrates, metal containing- glasses, ceramic and inorganic pigments, alloys, and UVCBs produced during the manufacturing of metals present specificities not addressed by most guidance documents. This book explains the main characteristics of inorganic complex materials affecting their hazard and risk assessment and management, including their source and main uses, also covering hazard and exposure assessment, risk characterization and risk management. It is an essential reference for regulators involved in risk assessment and risk management, industry experts charged of compliance with chemical management program requirements, consultants preparing chemicals management files for companies and regulators, and academics involved in research on complex inorganic materials.

  • Fungal Phylogenetics and Phylogenomics

    • 1st Edition
    • Volume 100
    • English
    Fungal Phylogenetics and Phylogenomics, Volume 100, the latest release in the Advances in Genetics series, presents users with new chapters that delve into such topics as the Advances of fungal phylogenomics and the impact on fungal systematics, Data crunching for fungal phylogenomics: insights into data collection and phylogenetic inference based on genome data for fungi, Genomic and epigenomic traits of emerging fungal pathogens, Advances in fungal gene cluster diversity and evolution, Phylogenomics of Fusarium oxysporum species complex, Phylogenomic analyses of pathogenic yeasts, and the Phylogenetics and phylogenomics of rust fungi. The series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions.

  • The Lateralized Brain

    The Neuroscience and Evolution of Hemispheric Asymmetries
    • 1st Edition
    • Sebastian Ocklenburg + 1 more
    • English
    The Lateralized Brain: The Neuroscience and Evolution of Hemispheric Asymmetries is an up-to-date teaching resource for neuroscience faculty members that teach courses concerning hemispheric asymmetries. The book provides students with all relevant information on the subject, while also giving aspiring researchers in the field an up-to-date overview of relevant, previous work. It is ideal for courses on hemispheric asymmetries, that is, the functional or structural differences between the left and the right hemispheres of the brain, and also highlights how the widespread use of modern neuroimaging techniques, such as fMRI and DTI has completely changed the way hemispheric asymmetries are currently investigated. According to the preface, the main aim of The Lateralized Brain is to provide "an up-to-date teaching resource on hemispheric asymmetries … [and] to introduce undergraduate students of all levels to the fascinating topics of hemispheric asymmetries" (p. xv)… (Sebastian Ocklenburg and Onur Güntürkün) have succeeded admirably in their stated aim and are to be congratulated on undertaking the mammoth task they set themselves. They can be proud of what they have accomplished.~ Alan A. Beaton, Department of Psychology, Swansea University, Swansea, UK, in Laterality: Asymmetries of Body, Brain and Cognition, July, 2018.

  • Meat Analogs

    Challenges and Perspectives
    • 1st Edition
    • Christophe Terrien
    • English
    Meat Analogs: Challenges and Perspectives provides an overview on the subject that is followed by an inventory of research perspectives to highlight the importance of issues and research relating to meat analogs. It explores the severe demographic, ecological, and economic and sociological constraints and uncertainties that exist in the allocation of food production resources. Alternative solutions, in particular meat substitutes, aka, meat analogs or mock-meats are discussed, as are dietary patterns and the control of markets.

  • Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health

    • 1st Edition
    • Suresh C Sikka + 1 more
    • English
    Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health is structured into two parts related to men’s reproductive and sexual health with eight sections designed to enable a logical flow of such knowledge. The book is focused on the biology of key organs involved in male reproduction and the environmental influences affecting their functions with particular emphasis on clinical aspects. Individual chapters within the book range from basic to translational aspects, but all hold clinical relevance. This is an essential reference for those working and learning in the field of human reproduction, reproductive toxicology and environmental influences on reproductive and sexual health.

  • Handbook of Neuroemergency Clinical Trials

    • 2nd Edition
    • Brett E. Skolnick + 1 more
    • English
    Handbook of Neuroemergency Clinical Trials, Second Edition, focuses on the practice of clinical trials in acute neuroscience populations, or what have been called neuroemergencies. Neuroemergencies are complex, life-threatening diseases and disorders, often with devastating consequences, including death or disability. The overall costs are staggering in terms of annual incidence and costs associated with treatment and survival, yet despite their significance as public health issues, there are few drugs and devices available for definitive treatment. The book focuses on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. This volume provides neurologists, neuroscientists, and drug developers with a more complete understanding of the scientific and medical issues of relevance in designing and initiating clinical development plans for novel drugs intended for acute neuroscience populations. The editors provide the best understanding of the pitfalls associated with acute CNS drug development and the best information on how to approach and solve issues that have plagued drug development.

  • Epigenetics of Aging and Longevity

    Translational Epigenetics vol 4
    • 1st Edition
    • Volume 4
    • Alexey Moskalev + 1 more
    • English
    Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses—including cancer and cardiovascular, metabolic, and neurodegenerative diseases—are explored in detail. This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease.

  • Fundamentals of Soil Ecology

    • 3rd Edition
    • David C. Coleman + 2 more
    • English
    Fundamentals of Soil Ecology, 3rd Edition,　offers a holistic approach to soil biology and ecosystem function, providing students and ecosystem researchers with a greater understanding of the central roles that soils play in ecosystem development and function. The text emphasizes the increasing importance of soils as the organizing center for all terrestrial ecosystems and provides an overview of theory and practice in soil ecology, both from an ecosystem and evolutionary biology point of view. This new edition is fully updated, including an expanded treatment of microbial ecology and new sections on advances in molecular techniques and climate change research. These updates make this edition an essential resource for researchers and students in soil ecology and microbiology.

  • Human Biochemistry

    • 1st Edition
    • Gerald Litwack
    • English
    Human Biochemistry includes clinical case studies and applications that are useful to medical, dentistry and pharmacy students. It enables users to practice for future careers as both clinicians and researchers. Offering immediate application of biochemical principles into clinical terms in an updated way, this book is the unparalleled textbook for medical biochemistry courses in medical, dental and pharmacy programs.

  • Reasoning

    The Neuroscience of How We Think
    • 1st Edition
    • Daniel Krawczyk
    • English
    Reasoning: The Neuroscience of How We Think is a comprehensive guide to the core topics related to a thorough understanding of reasoning. It presents the current knowledge of the subject in a unified, complete manner, ranging from animal studies, to applied situations, and is the only book available that presents a sustained focus on the neurobiological processes behind reasoning throughout all chapters, while also synthesizing research from animal behavior, cognitive psychology, development, and philosophy for a truly multidisciplinary approach. The book considers historical perspectives, state-of-the-art research methods, and future directions in emerging technology and cognitive enhancement. Written by an expert in the field, this book provides a coherent and structured narrative appropriate for students in need of an introduction to the topic of reasoning as well as researchers seeking well-rounded foundational content. It is essential reading for neuroscientists, cognitive scientists, neuropsychologists and others interested in the neural mechanisms behind thinking, reasoning and higher cognition.

  • Epigenetic Mechanisms in Cancer

    • 1st Edition
    • Volume 3
    • Sabita Saldanha
    • English
    Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnosis, prognosis, prediction, and risk assessment. This volumes offers a unique evaluation of signature differences in childhood, sex-specific and race-specific cancers, and in doing so broadly illuminates the scope of epigenetic biomarkers in clinical environments. Chapters detail the major epigenetic process in humans consisting of DNA methylation, histone modifications and microRNAs (miRNAs) involved in the initiation, progression and metastasis of tumors. Also delineated are recent technologies such as next generation sequencing that are used to identify epigenetic profiles (primarily methylation analysis) in samples (normal, benign and cancerous) and which are highly important to the analysis of epigenetic outcomes.

  • Vitamin D, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 46-4
    • J. Chris Gallagher + 1 more
    • English
    This issue of Endocrinology and Metabolism Clinics, guest edited by Drs. J. Chris Gallagher and Daniel Bikle, is devoted to Vitamin D. Articles in this issue include: The Molecular and Cellular Mechanisms of Action of Vitamin D, Worldwide Review of Serum 25OHD Status; RDA Update (7 Years Post IOM); The Use of Vitamin D Metabolites and Analogs in the Treatment of Chronic Kidney Disease; Effect of Vitamin D on Falls and Physical Performance; Vitamin D Effect on BMD and Fractures; Bariatric Surgery and Vitamin D Metabolism, Role of Vitamin D in the Prevention and Treatment of Cancer; Role of Vitamin D in Cardiovascular Disease; Regulation of Immune Function by Vitamin D and its Use in Diseases of Immunity; Genetic Diseases of Vitamin D Metabolizing Enzymes; Measurement of Vitamin D Metabolites: Clinical Issues; The Free 25OHD Hypothesis, and Ethnic/Racial Differences in Vitamin D Levels: Physiologic or Pathologic.

  • Case Studies in the Traditional Food Sector

    A volume in the Consumer Science and Strategic Marketing series
    • 1st Edition
    • Alessio Cavicchi + 1 more
    • English
    Consumer Science and Strategic Marketing: Case Studies in the Traditional Food Sector aims to close the gap between academic researchers and industry professionals through real world scenarios and field-based research. The book explores how consumer and sensory science has been implemented in the food industry for achieving the following strategic aims: rejuvenating product image, shaping new market places, achieving market differentiation and geographical diffusion, achieving customer loyalty, promoting traditional features of the product and defining product positioning in competitive environment. There is an emerging demand from food industry professionals and undergraduate and postgraduate students who attend business and agricultural studies courses who want to gain practical information through real cases and field-based research. This book aims to answer the following questions, amongst others: How research in the field of consumer science became relevant for marketing strategies?, Which tangible economic and financial outcomes have been obtained by the joint work of sensory scientists, researchers in marketing field and food business professionals?, and which communication methods and practices have been relevant to make the most of R&D in the food industry? Through case studies, successful examples and practices are provided, with newer inputs for further theoretical investigation given. Both current and future professionals in the food industry will gain insights that can be used in their business environment.

  • Genetics of Bone Biology and Skeletal Disease

    • 2nd Edition
    • Rajesh V. Thakker + 3 more
    • English
    Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets.

  • Disaster Epidemiology

    Methods and Applications
    • 1st Edition
    • Jennifer Horney
    • English
    Disaster Epidemiology: Methods and Applications applies the core methods of epidemiological research and practice to the assessment of the short- and long-term health effects of disasters. The persistent movement of people and economic development to regions vulnerable to natural disasters, as well as new vulnerabilities related to environmental, technological, and terrorism incidents, means that in spite of large global efforts to reduce the impacts and costs of disasters, average annual expenditures to fund rebuilding from catastrophic losses is rising faster than either population or the gross world product. Improving the resilience of individuals and communities to these natural and technological disasters, climate change, and other natural and manmade stressors is one of the grand challenges of the 21st century. This book provides a guide to disaster epidemiology methods, supported with applications from practice. It helps researchers, public health practitioners, and governmental policy makers to better quantify the impacts of disaster on the health of individuals and communities to enhance resilience to future disasters. Disaster Epidemiology: Methods and Applications explains how public health surveillance, rapid assessments, and other epidemiologic studies can be conducted in the post-disaster setting to prevent injury, illness, or death; provide accurate and timely information for decisions makers; and improve prevention and mitigation strategies for future disasters. These methods can also be applied to the study of other types of public health emergencies, such as infectious outbreaks, emerging and re-emerging diseases, and refugee health. This book gives both the public health practitioner and researcher the tools they need to conduct epidemiological studies in a disaster setting and can be used as a reference or as part of a course.

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