Ion Transport and Membrane Interactions in Vascular Health and Disease
- 1st Edition, Volume 90 - November 7, 2022
- Imprint: Academic Press
- Editor: Michael Sturek
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 9 7 8 8 - 1
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 9 7 8 9 - 8
Ion Transport and Membrane Interactions in Vascular Health and Disease, Volume 90 in the Current Topics in Membranes series, highlights advances in the field, with this new volu… Read more
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Request a sales quoteIon Transport and Membrane Interactions in Vascular Health and Disease, Volume 90 in the Current Topics in Membranes series, highlights advances in the field, with this new volume including chapters on an Introduction to Ion transport and membrane interactions in vascular health and disease, Endothelial cell microdomains of Ca2+ and metabolism, Cytoplasmic nanojunctions between smooth muscle organelles control specific Ca2+ signaling, TRPML channels in coronary vascular phenotypic modulation and calcification, Local voltage-gated Ca2+ channel regulation of vascular smooth muscle in diabetes, Biphasic changes in smooth muscle Ca2+ transporters during the progression of coronary atherosclerosis, Role of K+ channels in atherosclerosis, and more.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in the Current Topics in Membranes series
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- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Acknowledgments
- Chapter One: Introduction to ion transport and membrane interactions in vascular health and disease
- Abstract
- 1: Vascular specificity in health and disease
- 2: Metabolic disease milieu and experimental approaches and models
- 3: Snapshot of ion transport and membrane interactions
- 4: Conclusions and future directions
- Acknowledgments
- References
- Chapter Two: An unexpected effect of risperidone reveals a nonlinear relationship between cytosolic Ca2+ and mitochondrial Ca2+ uptake
- Abstract
- Data availability
- 1: Introduction
- 2: Materials and methods
- 3: Results
- 4: Discussion
- Conflict of interest
- Acknowledgments
- Author contributions
- References
- Chapter Three: Regulation of exosome release by lysosomal acid ceramidase in coronary arterial endothelial cells: Role of TRPML1 channel
- Abstract
- 1: Introduction
- 2: Materials and methods
- 3: Results
- 4: Discussion
- References
- Chapter Four: Vascular CaV1.2 channels in diabetes
- Abstract
- 1: Introduction
- 2: General L-type Ca2 + channel CaV1.2 structure
- 3: Regulation of vascular CaV1.2 channels
- 4: Effects of hyperglycemia on CaV1.2
- 5: Mechanisms of hyperglycemia-induced regulation of vascular CaV1.2 channels
- 6: Conclusions and future directions
- Acknowledgments
- References
- Chapter Five: Multiphasic changes in smooth muscle Ca2+ transporters during the progression of coronary atherosclerosis
- Abstract
- 1: Overview of vascular smooth muscle intracellular Ca2+ regulation in health
- 2: Smooth muscle phenotypic modulation and [Ca2+]i handling alterations
- 3: Metabolic syndrome “milieu”
- 4: Atherogenesis
- 5: Function/dysfunction of Ca2+ transporters during coronary atherosclerosis progression in swine
- 6: SERCA stimulation induces coronary smooth muscle proliferation in early atherosclerosis
- 7: Similarity of swine and human coronary atherosclerosis and smooth muscle Ca2+ signaling
- 8: Multiphasic model of coronary smooth muscle Ca2+ transporter regulation in atherosclerosis
- 9: Conclusions and future directions
- Acknowledgments
- References
- Chapter Six: Specificity of Ca2 +-activated K+ channel modulation in atherosclerosis and aerobic exercise training
- Abstract
- 1: General information on main types of K+ channels
- 2: Physiological roles of KCa channels
- 3: Effects of chronic exercise on reduction of cardiovascular disease and underlying K+ channel adaptations
- 4: Conclusions and future directions
- Acknowledgments
- References
- Chapter Seven: K+ channels in the coronary microvasculature of the ischemic heart
- Abstract
- 1: Introduction
- 2: Porcine model of ischemic heart disease
- 3: Role of K+ channels in basal active tone of arterioles from ischemic myocardium
- 4: Kv channels in arteriolar smooth muscle cells of ischemic myocardium
- 5: BKCa channels in arteriolar smooth muscle cells of ischemic myocardium
- 6: Role of additional K+ channel subfamilies in control of basal tone and vasodilation
- 7: Conclusion
- References
- Edition: 1
- Volume: 90
- Published: November 7, 2022
- No. of pages (Hardback): 180
- No. of pages (eBook): 180
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780323997881
- eBook ISBN: 9780323997898
MS
Michael Sturek
Michael Sturek is a Professor of Anatomy, Cell Biology & Physiology from Indiana University.
Affiliations and expertise
Indiana University, School of Medicine, Indianapolis, USARead Ion Transport and Membrane Interactions in Vascular Health and Disease on ScienceDirect