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Neuroimaging in Parkinson’s Disease and Related Disorders

  • 1st Edition - November 6, 2022
  • Latest edition
  • Editors: Marios Politis, Heather Wilson, Edoardo Rosario de Natale
  • Language: English

Neuroimaging in Parkinson’s Disease and Related Disorders discusses the advances of molecular, structural and functional neuroimaging techniques associated with the etiology,… Read more

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Description

Neuroimaging in Parkinson’s Disease and Related Disorders discusses the advances of molecular, structural and functional neuroimaging techniques associated with the etiology, pathophysiology, effects and complications of novel therapies in Parkinson’s and related disorders. With new neuroimaging methodologies emerging over the past five years, this book provides a comprehensive overview of new technologies and research. Sections discuss the biomarker value of neuroimaging of the brain to understand disease progression in vivo in actual patients with Parkinson’s disease and related disorders. Readers will be updated on in vivo pathology and pathophysiology in Parkinson’s disease and in a number of related disorders.

Also discussed is the association between clinical symptoms, clinical progression, and molecular, structural, and functional changes in the brain of patients with Parkinson’s disease and related disorders.

Key features

  • Comprehensive overview of biomarker value of neuroimaging of the brain to understand disease progression in vivo in actual patients with Parkinson’s disease and related disorders
  • Helps readers understand the in vivo pathology and pathophysiology in Parkinson’s disease and in a number of related disorders
  • Discusses the association between clinical symptoms, clinical progression, and molecular, structural, and functional changes in the brain of patients with Parkinson’s and related disorders

Readership

Neurologists, neuroscientists, nuclear medicine professionals, Pharma researchers

Table of contents

Section I. Introduction

1. Parkinson’s disease and related disorders: The pursuit for reliable readouts and the role of neuroimaging

2. Advances in magnetic resonance imaging

3. Advances in molecular neuromaging methodology

Section II. Clinical Applications in Parkinson's Disease

4. Dopaminergic molecular imaging in familial and idiopathic Parkinson's disease

5. Serotonergic molecular imaging in familial and idiopathic PD

6. Molecular imaging beyond dopamine and serotonin in familial and idiopathic Parkinson's disease

7. Structural MRI in familial and idiopathic PD

8. Functional MRI in familial and idiopathic PD

9. Molecular imaging in prodromal Parkinson's disease

Section III. Clinical Applications in Lewy Body Dementias

10. Molecular imaging evidence in favor or against PDD and DLB overlap

11. Magnetic resonance imaging in Parkinson's disease with mild cognitive impairment, Parkinson's disease dementia, and dementia with Lewy bodies

Section IV. Clinical Applications in Atypical Parkinsonian Disorders

12. Neuroimaging in multiple system atrophy

13. Neuroimaging in progressive supranuclear palsy

14. Neuroimaging in corticobasal syndrome

Section V. Clinical Applications in Other Movement Disorders

15. Molecular imaging in Huntington's disease

16. Magnetic resonance imaging in Huntington’s disease

17. Neuroimaging in essential tremor

18. Neuroimaging in restless legs syndrome

19. Neuroimaging in dystonia

20. Demyelinating syndromes and movement disorders

Product details

  • Edition: 1
  • Latest edition
  • Published: November 6, 2022
  • Language: English

About the editors

MP

Marios Politis

University of Exeter, United Kingdom Marios Politis is a Professor of Neurology, Consultant Neurologist, the Director of Mireille Gillings Neuroimaging Center, and the Director of the Neurodegeneration Imaging Group at University of Exeter. His research involves clinical observation and the use of PET and MR imaging as a method of investigating etiology, pathophysiology, and effects and complications of novel therapies in neurodegenerative disorders such as Parkinson’s disease. He has served as a chief investigator in a number of observational and interventional trials. Professor Politis has received a high number of awards and distinctions such as from the Movement Disorder Society, Royal College of Physicians, Society of Nuclear Medicine and Molecular Imaging, and European Academy of Neurology. He is a recipient of the John Stolk Award in Movement Disorders from the American Academy of Neurology.
Affiliations and expertise
University of Exeter, United Kingdom

HW

Heather Wilson

Heather Wilson, MSc. PhD, is a Senior Research Fellow at the Neurodegeneration Imaging Group, and Imaging Methodology Lead at the Mireille Gillings Neuroimaging Centre, University of Exeter.
Affiliations and expertise
Neurodegeneration Imaging Group and Mireille Gillings Neuroimaging Centre, University of Exeter, London, United Kingdom

Ed

Edoardo Rosario de Natale

Edoardo Rosario de Natale is a Senior Clinical Research Fellow at the Neurodegeneration Imaging Group at University of Exeter, lead of the clinical applications at the Mireille Gillings Neuroimaging Centre and honorary Consultant at the Royal Devon & Exeter NHS Foundation Trust.
Affiliations and expertise
Neurodegeneration Imaging Group and Mireille Gillings Neuroimaging Centre, University of Exeter, London, United Kingdom

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