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Elsevier

Books in Life sciences

  • International Review of Cell and Molecular Biology

    • 1st Edition
    • Volume 308
    • Kwang W. Jeon
    • English
    International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a world-wide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists. Impact factor for 2012: 4.973.

  • Speech Enhancement

    A Signal Subspace Perspective
    • 1st Edition
    • Jacob Benesty + 3 more
    • English
    Speech enhancement is a classical problem in signal processing, yet still largely unsolved. Two of the conventional approaches for solving this problem are linear filtering, like the classical Wiener filter, and subspace methods. These approaches have traditionally been treated as different classes of methods and have been introduced in somewhat different contexts. Linear filtering methods originate in stochastic processes, while subspace methods have largely been based on developments in numerical linear algebra and matrix approximation theory. This book bridges the gap between these two classes of methods by showing how the ideas behind subspace methods can be incorporated into traditional linear filtering. In the context of subspace methods, the enhancement problem can then be seen as a classical linear filter design problem. This means that various solutions can more easily be compared and their performance bounded and assessed in terms of noise reduction and speech distortion. The book shows how various filter designs can be obtained in this framework, including the maximum SNR, Wiener, LCMV, and MVDR filters, and how these can be applied in various contexts, like in single-channel and multichannel speech enhancement, and in both the time and frequency domains.

  • Toxicogenomics-Based Cellular Models

    Alternatives to Animal Testing for Safety Assessment
    • 1st Edition
    • Jos Kleinjans
    • English
    Toxicogenomics-Based Cellular Models is a unique and valuable reference for all academic and professional researchers employing toxicogenomic methods with respect to animal testing for chemical safety. This resource offers cutting-edge information on the application of toxicogenomics to developing alternatives to current animal toxicity tests. By illustrating the development of toxicogenomics-based cellular models for critical endpoints of toxicity and providing real-world examples for validation and data analysis, this book provides an assessment of the current state of the field, as well as opportunities and challenges for the future. Written by renowned international toxicological experts, this book explores ‘omics technology for developing new assays for toxicity testing and safety assessment and provides the reader with a focused examination of alternative means to animal testing.

  • Endocrine Disrupters

    • 1st Edition
    • Volume 94
    • English
    First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on endocrine disrupters.

  • Barley

    Chemistry and Technology, Second Edition
    • 1st Edition
    • Peter R. Shewry + 1 more
    • English
    Barley: Chemistry and Technology, Second Edition is an important resource for any cereal chemist, food scientist, or crop scientist who needs to understand the development, structure, composition, and end-use properties of the barley grain for cultivation, trade, and utilization. Editors Peter R. Shewry and Steven E. Ullrich bring together a wide range of international authorities on barley to create this truly unique, encyclopedic reference work that covers the massive increase in barley knowledge over the past 20 years, since the first edition of this book was published. Barley: Chemistry and Technology, Second Edition offers the latest coverage of barley’s applications in milling, breeding, and production for food, feed, malting, brewing, distilling, and biofuels. It delivers a complete update of the latest knowledge of barley’s many components, from the genetic and molecular level to its many constituents, such as proteins, carbohydrates, arabinoxylans, minerals, lipids, terpenoids, phenolics, and vitamins. This important book also includes chapters on barley’s plant and grain development from both the physiological and genetic perspectives, making it an important resource not only for cereal and food scientists but also for crop scientists involved in breeding, agronomy, and related plant sciences

  • Minerals in Animal and Human Nutrition

    Comparative Aspects to Human Nutrition
    • 1st Edition
    • Lee Russell McDowell
    • English
    This book presents concise, up-to-date information on mineral nutrition for livestock and poultry, as well as comparative aspects with laboratory animals and humans. Chapters are organized by established and most common minerals and present information on each mineral's properties, distribution, and natural sources, as well as their requirements, metabolism, functions, deficiencies, and toxicity in various animals. Minerals in which naturally occurring deficiencies or excesses are known to be of economic importance are emphasized. Many practical implications of deficiencies and excesses are also discussed along with methods sources of supplementation.This is both a comprehensive textbook and reference manual that will be useful for animal and veterinary scientists, nutritionists, and human medical researchers. It will also be valuable for feed manufacturers, livestock extension specialists, and farmers.

  • The Nude Mouse in Experimental and Clinical Research

    • 1st Edition
    • Jorgen Fogh
    • English
    The Nude Mouse in Experimental and Clinical Research presents the state of knowledge regarding the nude mouse and its applications to different branches of scientific research. The research studies featured in this book emphasize the academic status of a broad range of subjects and techniques of nude mouse research. The text consists of 21 chapters, each discussing an important aspect of nude mouse research. Some chapters discuss the biological aspect such as physiology, genes, and breeding and mass production of the mouse. A number of the chapters also discuss the general observations of the mouse like histopathological observations and their background. The applications of the nude mouse to human tumor and cancer cell research are likewise given emphasis. This book will be of valuable importance to both students and researchers in the fields of medicine, biology, and pathology.

  • Rye and Health

    • 1st Edition
    • Kaisa Poutanen + 1 more
    • English
    Rye has been known to stimulate weight loss, prevent gallstones, lower the risk of type 2 diabetes, promote gastrointestinal health, and improve cardiovascular conditions. Given rye’s many health benefits, it’s no wonder that nutritionists, the grains industry, and in turn consumers have been giving this healthy grain much more attention. Rye and Health, edited by veteran food technology and nutrition scientists Kaisa Poutanen and Per Åman, explains in detail the composition of rye and its physiological and health effects on humans using the latest research and information available

  • Animal Cell Culture Methods

    • 1st Edition
    • Volume 57
    • English
    This volume provides complete and thorough coverage of the classical and state-of-the-art methods used in cell culture. It also includes basic principles used in the selection of cells for specific scientific study, as well as analytical and procedural techniques.

  • Advances in Immunology

    • 1st Edition
    • Volume 121
    • Frederick W. Alt
    • English
    Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

  • Guide to Food Safety and Quality During Transportation

    Controls, Standards and Practices
    • 1st Edition
    • John M. Ryan
    • English
    Guide to Food Safety and Quality During Transportation provides a sound foundation for the improvement of the transportation sector responsible for the movement of food. While food safety agencies have been focused on producer, processor, retail, and restaurant food safety, the industry that moves the food has been largely overlooked. Ensuring trucks and containers are properly cleaned and disinfected, proper maintenance of refrigeration temperatures during transport, and avoiding paperwork delays are all areas of concern. Lack of government oversight has resulted in multiple, non-standardized approaches to food safety that are inspection-dependent... This book focuses specifically on the food movers normally overlooked by today's food safety auditors, compliance schemes, government agencies, quality control personnel, and transportation executives. It outlines delivery control solutions and provides basic standards designed to protect the transportation industry, as well as addressing problems associated with food transportation and practical solutions that are focused on container sanitation and traceability food safety and quality needs.

  • New Models of the Cell Nucleus: Crowding, Entropic Forces, Phase Separation, and Fractals

    • 1st Edition
    • Volume 307
    • Ronald Hancock + 1 more
    • English
    International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2012: 4.973. Ideas from the fields of biophysics, physical chemistry, of polymer and colloid, and soft matter science have helped clarify the structure and functions of the cell nucleus. The development of powerful methods for modeling conformations and interactions of macromolecules has also contributed. The book aims to encourage cell and molecular biologists to become more familiar with and understand these new concepts and methods, and the crucial contributions they are making to our perception of the nucleus.

  • Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

    Volume 3 - Role in Specific Diseases
    • 1st Edition
    • M. A. Hayat
    • English
    Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and up-to-date, this book offers a valuable guide to these cellular processes whilst encouraging researchers to explore their potentially important connections. Volume 3 explores the role of autophagy in specific diseases and developments, including: Crohn’s Disease, Gaucher Disease, Huntington’s Disease, HCV infection, osteoarthritis, and liver injury. A full section is devoted to in-depth exploration of autophagy in tumor development and cancer. Finally, the work explores the relationship between autophagy and apoptosis, with attention to the ways in which autophagy regulates apoptosis, and the ways in which autophagy has been explored in Lepidoptera, elucidating the use of larval midgut as a model for such exploration. From these well-developed foundations, researchers, translational scientists, and practitioners may work to better implement more effective therapies against some of the most devastating human diseases. Volumes in the Series Volume 1: Molecular Mechanisms. Elucidates autophagy’s association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer’s, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Volume 2: Role in General Diseases. Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases. Volume 3: Role in Specific Diseases. Explores the role of autophagy in specific diseases and developments, including: Crohn’s Disease, Gaucher Disease, Huntington’s Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis.Volume 4: Mitophagy. Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson Disease, cardiac aging, and skeletal muscle atrophy. Volume 5: Role in Human Diseases. Comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy’s effects in various cardiovascular, metabolic, and neurodegenerative disorders.Volume 6: Regulation of Autophagy and Selective Autophagy. Provides coverage of the mechanisms of regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity; and selective autophagy. Volume 7: Role of Autophagy in Therapeutic Applications. Provides coverage of the latest developments in autophagosome biogenesis and regulation; the role of autophagy in protein quality control; the role of autophagy in apoptosis; autophagy in the cardiovascular system; and the relationships between autophagy and lifestyle. Volume 8: Autophagy and Human Diseases. Reviews recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, and introduces new, more effective therapeutic strategies, in the development of targeted drugs and programmed cell death, providing information that will aid on preventing detrimental inflammation.Volume 9: Necrosis and Inflammation in Human Diseases. Emphasizes the role of Autophagy in necrosis and inflammation, explaining in detail the molecular mechanism(s) underlying the formation of autophagosomes, including the progression of Omegasomes to autophagosomes.

  • Advances in Virus Research

    • 1st Edition
    • Volume 88
    • English
    The first review series in virology and published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews, providing a valuable overview of the field.

  • Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics

    • 1st Edition
    • Carl Faingold + 1 more
    • English
    Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: How the brain carries out important tasks via networks How these networks interact in normal brain function Major mechanisms that control network function The interaction of the normal networks to produce more complex behaviors How brain disorders can result from abnormal interactions How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders.

  • Endosome Signaling Part B

    • 1st Edition
    • Volume 535
    • English
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This is the second of two volumes on endosome signaling and includes chapters on such topics as measurement of entry into the endosomal compartment by multi-parametric image analysis, assessment of peptide internalization and endosomal signaling, and VEGF-A in endosomal signaling.

  • Glucose Homeostatis and the Pathogenesis of Diabetes Mellitus

    • 1st Edition
    • Volume 121
    • English
    Diabetes mellitus is a disease with tremendous health and economic burden. A better understanding of how normal glucose homeostasis is maintained and the pathogenesis is important to identify new ways for diabetes treatment. This book addresses multiple aspects of this area of research.

  • Cellular and Molecular Pathobiology of Cardiovascular Disease

    • 1st Edition
    • Monte Willis + 2 more
    • English
    Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology.

  • Primer to the Immune Response

    • 2nd Edition
    • Tak W. Mak + 2 more
    • English
    Written in the same engaging conversational style as the acclaimed first edition, Primer to The Immune Response, 2nd Edition is a fully updated and invaluable resource for college and university students in life sciences, medicine and other health professions who need a concise but comprehensive introduction to immunology. The authors bring clarity and readability to their audience, offering a complete survey of the most fundamental concepts in basic and clinical immunology while conveying the subject’s fascinating appeal. The content of this new edition has been completely updated to include current information on all aspects of basic and clinical immunology. The superbly drawn figures are now in full color, complemented by full color plates throughout the book. The text is further enhanced by the inclusion of numerous tables, special topic boxes and brief notes that provide interesting insights. At the end of each chapter, a self-test quiz allows students to monitor their mastery of major concepts, while a set of conceptual questions prompts them to extrapolate further and extend their critical thinking. Moreover, as part of the Academic Cell line of textbooks, Primer to The Immune Response, 2nd Edition contains research passages that shine a spotlight on current experimental work reported in Cell Press articles. These articles also form the basis of case studies that are found in the associated online study guide and are designed to reinforce clinical connections.

  • Human Memory

    A Constructivist View
    • 1st Edition
    • Mary B. Howes + 1 more
    • English
    While memory research has recently focused on brain images and neurological underpinnings of transmitters, Human Memory: A Constructivist View assesses how our individual identity affects what we remember, why and how. This book brings memory back to the constructivist questions of how all the experiences of an individual, up to the point of new memory input, help to determine what that person pays attention to, how that information is interpreted, and how all that ultimately affects what goes into memory and how it is stored. This also affects what can be recalled later and what kind of memory distortions are likely to occur. The authors describe constructionist theories of memory, what they predict, how this is borne out in research findings, presenting everyday life examples for better understanding of the material and interest. Intended for memory researchers and graduate level courses, this book is an excellent summary of human memory research from the constructivist perspective.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 63
    • English
    Volume 63 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists. The serial provides the latest and most up-to-date technologies related to the field of Clinical Chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Psychology of Learning and Motivation

    • 1st Edition
    • Volume 60
    • English
    Psychology of Learning and Motivation publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Each chapter thoughtfully integrates the writings of leading contributors, who present and discuss significant bodies of research relevant to their discipline. Volume 60 includes chapters on such varied topics as the balance between mindfulness and mind-wandering; institutions; implications for the nature of memory traces; repetition, spacing, and abstraction; immediate repetition paradigms; stimulus-response compatibility effects; environmental knowledge; and the control of visual attention.

  • Good Health in the Tropics

    Advice to Travellers and Settlers
    • 1st Edition
    • W. H. Jopling
    • English
    Good Health in the Tropics: Advice to Travelers and Settlers presents a comprehensive health advice to those who are planning to travel to the tropics. The book is divided into two sections. Section I: Before Departure discusses what travelers should do before leaving the country such as medical and dental overhaul, immunization to take, clothes to wear, and medical supplies to bring. Section II: After Arrival focuses on the aspects of maintaining overall health and wellbeing while staying in the tropics. Topics discussed include certain diseases acquired during eating and drinking and bathing in lakes and rivers; protection from insect bites and skin diseases; general rules for healthy living in the tropics; and prevention of malaria. Travelers and settlers in the tropics will find the book invaluable.

  • Mesenchymal Stem Cells in Cancer Therapy

    • 1st Edition
    • Khalid Shah
    • English
    With the thorough understanding of stem cell biology and the advent of targeted therapeutics for cancer, stem cell-based therapeutic strategies are being increasingly explored for the treatment of various cancer types. Mesenchymal Stem Cells in Cancer Therapy sheds light on current stem cell based targeted therapies for cancer, by focusing on the application of mesenchymal stem cells (MSC) in various cancers with emphasis on a number of aspects that are critical to the success of future stem cell based therapies for cancer. Sections of this publication are devoted to developing stem cell based therapies for cancer with the main focus on tumoritrophic properties of stem cells, engineering targeted therapeutics, utilization of imaging techniques and the recent combination studies utilizing currently employed therapeutics with stem cells. Mesenchymal Stem Cells in Cancer Therapy informs readers about critical and cutting edge stem cell therapies for cancer and also enables them to appreciate the vast plain of unresolved questions in stem cell research for cancer therapeutics.

  • Genomes of Herbaceous Land Plants

    • 1st Edition
    • Volume 69
    • English
    Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. Currently in its 69th volume, the series features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. This thematic volume features reviews on genomes of herbaceous land plants

  • Advances in Agronomy

    • 1st Edition
    • Volume 123
    • English
    Advances in Agronomy continues to be recognized as a leading reference and a first-rate source for the latest research in agronomy. As always, the subjects covered are varied and exemplary of the myriad of subject matter dealt with by this long-running serial.

  • Equitable Solutions for Retaining a Robust STEM Workforce

    Beyond Best Practices
    • 1st Edition
    • Donna J. Dean + 1 more
    • English
    Equitable Solutions for Retaining a Robust STEM Workforce offers strategies and proven recommendations to accommodate work/life satisfaction for those in the STEM fields. Using real-life case studies, this book discusses universal issues such as dual careers and strategic decision making, childcare/dependent care in professional contexts, promoting family-friendly policies, as well as mentoring and networking. Equitable Solutions for Retaining a Robust STEM Workforce provides data and tools to drive successful programs relaying proactive solutions that STEM employers, academic institutions, policy-makers, and individuals can utilize.

  • Handbook of Nanosafety

    Measurement, Exposure and Toxicology
    • 1st Edition
    • Ulla Vogel + 5 more
    • English
    Handbook of Nanosafety: Measurement, Exposure and Toxicology, written by leading international experts in nanosafety, provides a comprehensive understanding of engineered nanomaterials (ENM), current international nanosafety regulation, and how ENM can be safely handled in the workplace. Increasingly, the importance of safety needs to be considered when promoting the use of novel technologies like ENM. With its use of case studies and exposure scenarios, Handbook of Nanosafety demonstrates techniques to assess exposure and risks and how these assessments can be applied to improve workers' safety. Topics covered include the effects of ENM on human health, characterization of ENM, aerosol dynamics and measurement, exposure and risk assessment, and safe handling of ENM. Based on outcomes from the NANODEVICE initiative, this is an essential resource for those who need to apply current nanotoxicological thinking in the workplace and anyone who advises on nanosafety, such as professionals in toxicology, occupational safety and risk assessment.

  • Endosome Signaling Part A

    • 1st Edition
    • Volume 534
    • English
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This is the first of two volumes on endosome signaling and includes chapters on such topics as measurement of entry into the endosomal compartment by multi-parametric image analysis, assessment of peptide internalization and endosomal signaling, and VEGF-A in endosomal signaling.

  • The Flagellar World

    Electron Microscopic Images of Bacterial Flagella and Related Surface Structures
    • 1st Edition
    • Shin-Ichi Aizawa
    • English
    The Flagellar World is a unique publication. The product of years of research and data collection by the author, this book is a pictorial guide to flagella in a variety of organisms. Each EM image is accompanied by a short description of the system in each organism. These never-before-seen pictures represent a wide variety of flagella, including Legionella pneumophila, Escherichia coli, Pseudomonas aeruginosa, and many others. Researchers in microbiology, immunology, and parasitology will find this a fascinating and useful resource.

  • Corn and Grain Sorghum Comparison

    All Things Considered
    • 1st Edition
    • Yared Assefa + 5 more
    • English
    Corn and grain sorghum (Sorghum bicolor subsp. bicolor L) are among the top cereal crops world wide, and both are key for global food security. Similarities between the two crops, particularly their adaptation for warm-season grain production, pose an opportunity for comparisons to inform appropriate cropping decisions. This book provides a comprehensive review of the similarities and differences between corn and grain sorghum. It compares corn and sorghum crops in areas such as morphology, physiology, phenology, yield, resource use and efficiency, and impact of both crops in different cropping systems. Producers, researchers and extension agents in search of reliable scientific information will find this in-depth comparison of crops with potential fit in dryland and irrigations cropping systems particularly valuable.

  • Light and Video Microscopy

    • 2nd Edition
    • Randy O. Wayne
    • English
    The purpose of this book is to provide the most comprehensive, easy-to-use, and informative guide on light microscopy. Light and Video Microscopy will prepare the reader for the accurate interpretation of an image and understanding of the living cell. With the presentation of geometrical optics, it will assist the reader in understanding image formation and light movement within the microscope. It also provides an explanation of the basic modes of light microscopy and the components of modern electronic imaging systems and guides the reader in determining the physicochemical information of living and developing cells, which influence interpretation.

  • Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases

    • 1st Edition
    • Christophe Wiart
    • English
    Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases is the second volume in the series, Pharmaceutical Leads from Medicinal Plants. This book includes key pharmacological and chemical evidence to support the selection of promising pre-clinical candidates for the treatment of neurodegenerative diseases. This important addition to the natural product and drug discovery literature contains the history, synonyms, medicinal uses, phytopharmacology, pre-clinical potential, and rationale for each plant selected. By providing critical evaluation of pharmacological data, mechanisms of action, and structural requirements for the development of future neuroprotective agents, this comprehensive reference is a beneficial resource for industry and academic scientists whose research focuses on neurodegenerative drug discovery and development.

  • Hygiene in Food Processing

    Principles and Practice
    • 2nd Edition
    • H.L.M. Lelieveld + 2 more
    • English
    The hygienic processing of food concerns both potential hazards in food products and the regulation, design, and management of food processing facilities. This second edition of Hygiene in Food Processing gives a revised overview of the practices for safe processing and incorporates additional chapters concerning pest control, microbiological environmental sampling, and the economics of food plants. Part one addresses microbial risks in foods and the corresponding regulation in the European Union. Part two discusses the hygienic design of food factory infrastructure, encompassing the design and materials for the factory itself, as well as food processing equipment. This edition includes a new chapter on the control of compressed gases used to pneumatically operate equipment. Part three focuses on cleaning and disinfection practices in food processing. The chapter on cleaning in place also considers more cost-effective systems, and complements the additional chapter on maintenance of equipment. These chapters also explore issues such as the hygiene of workers, potential infection by foreign bodies, and pest control. Further, the chapter on microbiological sampling explains how to calculate the risk of contamination depending on the product's environment. This essential second edition is useful to professionals responsible for hygiene in the food industry. It provides a comprehensive, yet concise and practical reference source for food plant managers, suppliers of food processing equipment, building contractors, and food inspectors looking for an authoritative introduction to hygiene regulation, hygienic design, and sanitation.

  • Encyclopedia of Food Safety

    • 1st Edition
    • Yasmine Motarjemi
    • English
    With the world’s growing population, the provision of a safe, nutritious and wholesome food supply for all has become a major challenge. To achieve this, effective risk management based on sound science and unbiased information is required by all stakeholders, including the food industry, governments and consumers themselves. In addition, the globalization of the food supply requires the harmonization of policies and standards based on a common understanding of food safety among authorities in countries around the world. With some 280 chapters, the Encyclopedia of Food Safety provides unbiased and concise overviews which form in total a comprehensive coverage of a broad range of food safety topics, which may be grouped under the following general categories: History and basic sciences that support food safety; Foodborne diseases, including surveillance and investigation; Foodborne hazards, including microbiological and chemical agents; Substances added to food, both directly and indirectly; Food technologies, including the latest developments; Food commodities, including their potential hazards and controls; Food safety management systems, including their elements and the roles of stakeholders. The Encyclopedia provides a platform for experts from the field of food safety and related fields, such as nutrition, food science and technology and environment to share and learn from state-of-the art expertise with the rest of the food safety community.

  • Literature, Neurology, and Neuroscience: Neurological and Psychiatric Disorders

    • 1st Edition
    • Volume 206
    • English
    This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume on the neurosciences, neurology, and literature vividly shows how science and the humanities can come together --- and have come together in the past. Its sections provide a new, broad look at these interactions, which have received surprisingly little attention in the past. Experts in the field cover literature as a window to neurological and scientific zeitgeists, theories of brain and mind in literature, famous authors and their suspected neurological disorders, and how neurological disorders and treatments have been described in literature. In addition, a myriad of other topics are covered, including some on famous authors whose important connections to the neurosciences have been overlooked (e.g., Roget, of Thesaurus fame), famous neuroscientists who should also be associated with literature, and some overlooked scientific and medical men who helped others produce great literary works (e,g., Bram Stoker's Dracula). There has not been a volume with this coverage in the past, and the connections it provides should prove fascinating to individuals in science, medicine, history, literature, and various other disciplines.

  • Extracellular Glycolipids of Yeasts

    Biodiversity, Biochemistry, and Prospects
    • 1st Edition
    • Ekaterina Kulakovskaya + 1 more
    • English
    Extracellular Glycolipids of Yeasts: Biodiversity, Biochemistry, and Prospects provides a comprehensive view of the biochemistry, biological activity, and practical application of extracellular glycolipids of yeast. This book brings much-needed clarity to the complex topic of glycolipids and streamlines the rather confusing terminology used for glycolipids. It also provides a wealth of modern data on their composition, structure and properties, biosynthetic pathways, methods of isolation and identification, antifungal activity, and mechanisms of action. Studies of extracellular glycolipids of yeast now draw the attention of researchers in life science and biotechnology due to numerous recently revealed biological properties of these compounds. These compounds are scientifically and practically promising in medicine and agriculture due to their biosurfactant and fungicidal properties, as well as a number of other biological activities. Extracellular Glycolipids of Yeasts gives researchers studying biochemistry of microorganisms and related biologically active compounds a much-needed guide to the basic data that will aid in these increasingly generative pursuits.

  • New Functional Biomaterials for Medicine and Healthcare

    • 1st Edition
    • Elena P. Ivanova + 2 more
    • English
    New Functional Biomaterials for Medicine and Healthcare provides a concise summary of the latest developments in key types of biomaterials. The book begins with an overview of the use of biomaterials in contemporary healthcare and the process of developing novel biomaterials; the key issues and challenges associated with the design of complex implantable systems are also highlighted. The book then reviews the main materials used in functional biomaterials, particularly their properties and applications. Individual chapters focus on both natural and synthetic polymers, metallic biomaterials, and bio-inert and bioactive ceramics. Advances in processing technologies and our understanding of materials and their properties have made it possible for scientists and engineers to develop more sophisticated biomaterials with more targeted functionality. New Functional Biomaterials for Medicine and Healthcare provides an ideal one-volume summary of this important field that represents essential reading for scientists, engineers, and clinicians, and a useful reference text for undergraduate and postgraduate students.

  • Global Safety of Fresh Produce

    A Handbook of Best Practice, Innovative Commercial Solutions and Case Studies
    • 1st Edition
    • Jeffrey Hoorfar
    • English
    Continuing food poisoning outbreaks around the globe have put fresh produce safety at the forefront of food research. Global Safety of Fresh Produce provides a detailed and comprehensive overview of best practice for produce safety throughout the food chain, and unique coverage of commercial technologies for fresh produce safety. Part one covers the production and regulation of fresh produce on the agricultural level, including issues of niche farm fresh products, FDA regulation, and zoonotic transfer of pathogens from animals to farm products. Part two moves on to look at safety and environmental issues surrounding fresh produce processing, such as postharvest washing, alternative sanitizers, and using produce waste as animal feed. Part three focuses on current and emerging commercial solutions for fresh produce safety, like ionizing radiation and edible coatings, and part four covers methods of laboratory testing and related legislation. The final section of the book covers a series of case studies of fresh produce safety breaches, including European E. coli outbreaks in sprouts and leafy greens, and the illegal use of fluorescent whitening agents (FWAs) in China. This book is an essential text for R&D managers in the fresh produce industry, quality control professionals working with fresh produce throughout the food chain, postgraduate students, and academic researchers with an interest in fresh produce safety.

  • The Guide to Investigation of Mouse Pregnancy

    • 1st Edition
    • B. Anne Croy + 3 more
    • English
    The Guide to Investigation of Mouse Pregnancy is the first publication to cover the mouse placenta or the angiogenic tree the mother develops to support the placenta. This much-needed resource covers monitoring of the cardiovascular system, gestational programming of chronic adult disease, epigenetic regulation, gene imprinting, and stem cells. Offering detailed and integrated information on how drugs, biologics, stress, and manipulations impact pregnancy in the mouse model, this reference highlights techniques used to analyze mouse pregnancy. Joining the ranks of much referenced mouse resources, The Guide to Investigation of Mouse Pregnancy is the only manual providing needed content on pregnancy in animal models for translational medicine and research.

  • Social Predation

    How Group Living Benefits Predators and Prey
    • 1st Edition
    • Guy Beauchamp
    • English
    The classic literature on predation dealt almost exclusively with solitary predators and their prey. Going back to Lotka-Volterra and optimal foraging theory, the theory about predation, including predator-prey population dynamics, was developed for solitary species. Various consequences of sociality for predators have been considered only recently. Similarly, while it was long recognized that prey species can benefit from living in groups, research on the adaptive value of sociality for prey species mostly emerged in the 1970s. The main theme of this book is the various ways that predators and prey may benefit from living in groups. The first part focusses on predators and explores how group membership influences predation success rate, from searching to subduing prey. The second part focusses on how prey in groups can detect and escape predators. The final section explores group size and composition and how individuals respond over evolutionary times to the challenges posed by chasing or being chased by animals in groups. This book will help the reader understand current issues in social predation theory and provide a synthesis of the literature across a broad range of animal taxa.

  • Plant Virus-Host Interaction

    Molecular Approaches and Viral Evolution
    • 1st Edition
    • R.K. Gaur + 2 more
    • English
    Plant Virus-Host Interaction contains cutting-edge research in plant molecular virology, including pathogenic viroids and transport by insect vectors, interference with transmission to control viruses, and synergism, with pivotal coverage of RNA silencing and the counter-defensive strategies used by viruses to overcome the silencing response in plants. With a clear focus on plant virus evolution, including quantitative and population genetics, Plant Virus-Host Interaction provides insights on the major factors favoring disease emergence, such as genetic change in pathogen and host populations and changes in host ecology and environment. The book also examines socioeconomic implications of widespread plant viral agents. Contributions from leading experts around the globe provide varied perspectives, while comprehensive coverage ensures a complete look at this exciting field.

  • International Cooperation, Convergence and Harmonization of Pharmaceutical Regulations

    A Global Perspective
    • 1st Edition
    • Pierre-Louis Lezotre
    • English
    International Cooperation, Convergence and Harmonization of Pharmaceutical Regulations: A Global Perspective provides the current status of the complex and broad phenomenon of cooperation, convergence and harmonization in the pharmaceutical sector (Part I), thoroughly evaluates its added value and its critical parameters and influencing factors (Part II) in order to recommend actions and measures to support the next steps for cooperation, convergence and harmonization (Part III). All of these recommendations in the book support the establishment of a better coordinated global pharmaceutical system which represents the best realistic alternative to fulfill the objective to establish a global coalition of regulators and to respond to an increased demand to further cooperation in the pharmaceutical sector. This proposed framework, which leverages all of the ongoing positive cooperation initiatives and uses as foundations all of the numerous harmonization projects developed over the years, presents advantages for all stakeholders and would definitively have significant added value to the promotion and protection of global public health.

  • Modelling Methodology for Physiology and Medicine

    • 2nd Edition
    • Ewart Carson + 1 more
    • English
    Modelling Methodology for Physiology and Medicine, Second Edition, offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modeling methodology that is widely applicable to physiology and medicine. The second edition, which is completely updated and expanded, opens with a clear and integrated treatment of advanced methodology for developing mathematical models of physiology and medical systems. Readers are then shown how to apply this methodology beneficially to real-world problems in physiology and medicine, such as circulation and respiration. The focus of Modelling Methodology for Physiology and Medicine, Second Edition, is the methodology that underpins good modeling practice. It builds upon the idea of an integrated methodology for the development and testing of mathematical models. It covers many specific areas of methodology in which important advances have taken place over recent years and illustrates the application of good methodological practice in key areas of physiology and medicine. It builds on work that the editors have carried out over the past 30 years, working in cooperation with leading practitioners in the field.

  • Diagnostic Ultrasound Imaging: Inside Out

    • 2nd Edition
    • Thomas L. Szabo
    • English
    Diagnostic Ultrasound Imaging provides a unified description of the physical principles of ultrasound imaging, signal processing, systems and measurements. This comprehensive reference is a core resource for both graduate students and engineers in medical ultrasound research and design. With continuing rapid technological development of ultrasound in medical diagnosis, it is a critical subject for biomedical engineers, clinical and healthcare engineers and practitioners, medical physicists, and related professionals in the fields of signal and image processing. The book contains 17 new and updated chapters covering the fundamentals and latest advances in the area, and includes four appendices, 450 figures (60 available in color on the companion website), and almost 1,500 references. In addition to the continual influx of readers entering the field of ultrasound worldwide who need the broad grounding in the core technologies of ultrasound, this book provides those already working in these areas with clear and comprehensive expositions of these key new topics as well as introductions to state-of-the-art innovations in this field.

  • Catecholamine Research in the 21st Century

    Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012
    • 1st Edition
    • Lee E. Eiden
    • English
    Through the use of extended graphical abstracts and some traditional text-only abstracts this collection provides, a record of and roadmap to, the research presented at The Tenth International Catecholamine Symposium (XICS) held in September of 2012. Organized around ten general themes, each is introduced by a short overview identifying interesting research programs, results and potential areas of growth. The collection is a roadmap to key research and future opportunities for new catecholamine research programs and will be of interest to neuroscientists and clinical neurologists interested in understanding the current and future state of catecholamine research.

  • Handbook of Polymer Applications in Medicine and Medical Devices

    • 1st Edition
    • Kayvon Modjarrad + 1 more
    • English
    While the prevalence of plastics and elastomers in medical devices is now quite well known, there is less information available covering the use of medical devices and the applications of polymers beyond medical devices, such as in hydrogels, biopolymers and silicones beyond enhancement applications, and few books in which these are combined into a single reference. This book is a comprehensive reference source, bringing together a number of key medical polymer topics in one place for a broad audience of engineers and scientists, especially those currently developing new medical devices or seeking more information about current and future applications. In addition to a broad range of applications, the book also covers clinical outcomes and complications arising from the use of the polymers in the body, giving engineers a vital insight into the real world implications of the devices they’re creating. Regulatory issues are also covered in detail. The book also presents the latest developments on the use of polymers in medicine and development of nano-scale devices.

  • Green Vegetable Oil Processing

    Revsied First Edition
    • 1st Edition
    • Walter E. Farr + 1 more
    • English
    Alternative green food processing technologies have gained much technical and industrial attention in recent years as a potential means of reducing costs and promoting consumer awareness of corporate environmental responsibility. However, utilizing green principles is now becoming an effective business approach to enhance vegetable oil processing profitability. Two years have passed since the first edition of Green Vegetable Oil Processing was published. The Revised First Edition includes much of the content of the first edition, but incorporates updated data, details, images, figures, and captions. This book addresses alternative green technologies at various stages of oilseed and vegetable oil processing. This includes oil extraction technologies such as expeller, aqueous and supercritical methods, and green modifications of conventional unit operations such as degumming, refining, bleaching, hydrogenation, winterizing/dewaxing... fractionation, and deodorization. While most chapters describe soy oil processing, the techniques described equally applicable to oils and fats in general.

  • Fish Physiology: Organic Chemical Toxicology of Fishes

    • 1st Edition
    • Volume 33
    • Keith B. Tierney + 2 more
    • English
    Fish Physiology: Organic Chemical Toxicology of Fishes discusses the different types of organic chemical contaminants and their respective toxic effects in fish. The book also covers the detection of dissolved organic compounds and methods to assess organic toxicity. Substances addressed in this book include organometallics, hydrocarbons, endocrine disrupting compounds (EDCs), insecticides, herbicides, and pharmaceuticals. Fish are exposed to an ever-increasing array of organic chemicals that find their way into rivers and oceans. Some of these compounds are no longer being produced but nonetheless persist within the environment (persistent organic pollutants, or POPs). The exposure of fish to toxic organic compounds has potential impact on human, fish, and ecosystem health. Yet the regulations that govern environmental water quality vary worldwide, and compliance is never complete. This book provides a crucial resource on these issues for researchers in zoology, fish physiology, and related fields; applied researchers in environmental monitoring, conservation biology, and toxicology; and university-level students and instructors in these areas.

  • The Autoimmune Diseases

    • 5th Edition
    • M. Eric Gershwin + 1 more
    • English
    Since publication of the 4th Edition of The Autoimmune Diseases in 2006, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This fully revised 5th Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels and includes expanded coverage of autoinflammatory disease and autoimmune responses to tumors.

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