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Books in Life sciences

  • Advances in Immunology

    • 1st Edition
    • Volume 162
    • English
    Advances in Immunology, Volume 162, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.

  • Mechanisms of Disease Pathogenesis in Multiple Sclerosis

    • 1st Edition
    • Francisco Javier Quintana
    • English
    Mechanisms of Disease Pathogenesis in Multiple Sclerosis summarizes our current understanding on MS and its clinical features and monitoring with available biomarkers, focusing on mechanisms that drive disease pathogenesis and their control by genetic, environmental factors and novel therapies for disease management. The book is written for neurologists, neuroimmunologists and clinical, translational and basic researchers interested in mechanisms of neurodegeneration. Multiple Sclerosis (MS) is an autoimmune disease which targets the central nervous system (CNS). It is the most common cause of non-traumatic neurological disability in young adults with a prevalence of 1 in 1000 and increasing, hence the importance of this book.

  • Immune Landscape of Pancreatic Cancer Development and Drug Resistance

    • 1st Edition
    • Volume 5
    • Batoul Farran + 1 more
    • English
    Immune Landscape of Pancreatic Cancer Development and Drug Resistance explores advances in immune-based therapies aimed at harnessing the power of the immune system against pancreatic cancer and rewiring tumor microenvironments to eradicate pancreatic cells. With a strong focus on the development of therapeutic methods to improve the survival rates of pancreatic cancer, this book also shows the latest trends in immune targeted approaches for pancreatic cancer treatment. In 12 chapters, the book discusses our current understanding of PC development and its various mutational and immune features and explore some of the new immune-based therapies aimed at targeting pancreatic cancer. This book is a valuable resource for health professionals, scientists and researchers, students, and all those who wish to broaden their knowledge of advances in immunotherapy in pancreatic cancer.

  • Malabsorptive Surgeries

    Surgical Techniques, Results, and Challenges
    • 1st Edition
    • Jaime Ruiz Tovar
    • English
    Malabsorptive Surgery: Surgical Techniques, Results, and Challenges describes the development of classic and new malabsorptive surgical techniques. Coverage includes the results obtained after the procedures, as well as postoperative complications - including early complications (associated with the difficulty of the operation) and late complications (associated with nutritional sequelae). This book is the perfect reference for basic and translational research focused on the mechanism of action of malabsorptive procedures, that goes beyond the bypassing of intestinal loops, affecting the regulation of hormonal signals. The content is also useful for bariatric surgeons and endocrinologists dealing with the bariatric options and results.Despite the aims of bariatric surgery focusing on performing procedures associated with low postoperative complications rates (mostly restrictive procedures), there is increasing evidence showing mid- and long-term failure of restrictive and mixed procedures in terms of weight regain and recurrence of comorbidities. This has increased the need for revisional surgeries after failed primary procedures, and consequently, increased the popularity of malabsorptive techniques.

  • Treatment of Breast Cancer with Natural Products

    • 1st Edition
    • Yachana Mishra + 1 more
    • English
    Treatment of Breast Cancer with Natural Based Products is designed to provide a wide spectrum of information and knowledge on phytotherapeutics in breast cancer treatment. With a strong focus on the established research and technology on phytoconstituent-bas... nanocarriers, the book also covers their rapidly emerging aspects and discusses future research directions in the treatment of breast cancer. Users will find insights into breast cancer symptoms, epidemiology, risk factors, screening, treatment, and drugs delivery systems. Other sections cover Curcumin, Paclitaxel, Quercetin, Resveratrol, Sulforaphane, Epigallocatechin-3-G... Allicin, Berberine, and Vinca Alkaloids in the treatment of breast cancer, along with future perspectives.This book presents a groundbreaking opportunity for both academia and industry to reshape contemporary medical and healthcare approaches. With a specific emphasis on various facets of phytoconstituents within the realm of oncology, this publication serves as a precious asset for researchers, as well as graduate and post-graduate students specializing in oncology, pharmaceutical sciences, biotechnology, and related biomedical fields.

  • Onco-Palliative Care Essentials

    • 1st Edition
    • Azar Naveen Saleem + 2 more
    • English
    Onco-Palliative Care Essentials gives insight into the much-needed specialty to improve the quality of life of cancer patients. With a strong focus on the fundamental essentials of onco-palliative care, this book covers real-life cases with challenging cultural, existential, and social aspects.This book introduces the field of onco-palliative care to the reader, focusing on managing complex aspects associated with cancer and its treatment. It also helps the reader regarding approaches for “end of life care and discussion.” This book concludes with challenging care scenarios.Onco-Palli... Care Essentials is a very useful reference for all who are involved in cancer and palliative care, as well as those who care for cancer and terminally ill patients.

  • Joint Replacement in the Human Body

    • 1st Edition
    • Thomas J Joyce
    • English
    Joint Replacement in the Human Body provides a comprehensive exploration of artificial joint designs. The book's primary focus is to introduce readers to the diverse landscape of artificial joint technologies while offering insights into their historical development. This book is divided into three sections, each addressing specific aspects of joint replacements. The first section delves into artificial joints of the lower limb, including the hip, knee, and ankle. In the subsequent section, the book explores upper limb replacements, covering joints such as the shoulder, elbow, wrist, finger, and thumb.The third section tackles broader themes like biotribology, regulatory aspects of joint replacements, examines noteworthy case studies like metal-on-metal hips, and addresses joint replacements not easily categorized in the previous sections, such as spinal total disc replacements. This book offers a critical assessment of the diverse and evolving design concepts currently in use, ranging from established metal-on-polymer joints to innovative biomimetic solutions. This book is designed to swiftly equip readers with a deep understanding of contemporary joint replacements and the immediate and long-term challenges they present.

  • A Review on Diverse Neurological Disorders

    Pathophysiology, Molecular Mechanisms, and Therapeutics
    • 1st Edition
    • Rameshwar Nath Chaurasia + 2 more
    • English
    A Review of Diverse Neurological Disorders: Pathophysiology, Molecular Mechanisms, and Therapeutics offers an unparalleled compilation of the current understanding of neurodegenerative disorders. This book investigates the origins of mental disorders, encompassing bacterial and fungal invasions, viral assaults, and genetic predispositions, providing readers with a thorough grasp of the neurological landscape. Each chapter dissects the intricacies of these incapacitating conditions, ranging from the pathogenesis of central nervous system tuberculosis to the involvement of endocannabinoids in rabies infection. Topics such as neuroinflammation, axonal pathology, and the intricate relationship between diet, gut microbiomes, and cognitive decline are also explored. This book conducts an extensive examination of neurodegeneration, incorporating discussions on the role of probiotics and natural bioactive compounds in preventing ailments such as Parkinson’s, Alzheimer’s, and amyotrophic lateral sclerosis (ALS). With meticulous analyses of vitamins, micronutrients, antioxidants, and nutraceuticals, this work offers a roadmap for promoting neuroprotection. A Review of Diverse Neurological Disorders serves as a resource that not only reviews the current understanding but also lays the groundwork for future treatments and innovations.

  • Therapeutic Monoclonal Antibodies: From Lot Release to Stability Testing

    • 1st Edition
    • Harleen Kaur
    • English
    Therapeutic Monoclonal Antibodies: From Lot Release to Stability Testing is a highly topical resource on a subject of interest for scientists and researchers working on monoclonal antibodies' characterization, release testing, stability testing and similarity assessments of monoclonal antibodies in the biopharmaceutical industry. Monoclonal antibodies (mAbs) are large, extremely complex and dynamic biomolecules, so it can be challenging to develop well-characterized therapeutic antibodies that meet regulatory expectations that are also in-line with commercialized standards for different drug markets.Lot release testing and understanding the stability of the mAb over a period of time, and in different environmental conditions, is an indispensable aspect of mAb physicochemical characterization. This book covers the process, including extensive analysis that starts with quantifying the purity attribute to glycan profiling and identifying the mAb primary structure. The book has a primary purpose of focusing on both Lot release testing and stability testing of monoclonal antibodies (subjects not covered in any great detail in other books).

  • Magnetic Nanoparticles in Nanomedicine

    • 1st Edition
    • Kai Wu + 1 more
    • English
    Magnetic Nanoparticles in Nanomedicine provides readers with the fundamental theories and principles of magnetic materials, the synthesis and surface functionalization strategies of MNPs, and the standard techniques for characterizing physicochemical properties of MNPs. Other sections review MNP-based therapies such as magnetic hyperthermia therapy, drug/gene delivery, and magnetic neurostimulation and cover MNP-based in vitro and in vivo disease diagnosis, respectively, including techniques such as magnetoresistive (MR), nuclear magnetic resonance (NMR), magnetic particle spectroscopy (MPS) biosensing platforms, magnetic resonance imaging (MRI), and magnetic particle imaging (MPI).Final chapters address biocompatibility and safety issues in applying MNPs to in vivo biomedical applications, including coverage of the toxicity of MNPs to human tissues, the immune responses of the human body to these particles, as well as blood circulation time of MNPs.

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