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Advances in the Neurochemistry and Neuropharmacology of Tourette Syndrome
- 1st Edition, Volume 112 - November 27, 2013
- Editors: Davide Martino, Andrea E Cavanna
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 4 1 1 5 4 6 - 0
- eBook ISBN:9 7 8 - 0 - 1 2 - 4 1 1 5 6 1 - 3
This volume of International Review of Neurobiology brings together cutting-edge research on advances in the neurochemistry and neuropharmacology of Tourette syndrome. It reviews c… Read more
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Request a sales quoteThis volume of International Review of Neurobiology brings together cutting-edge research on advances in the neurochemistry and neuropharmacology of Tourette syndrome. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and includes important topics regards tics, neurotransmitters, pharmacology and emerging treatments.
- This volume of brings together research on tourettes synrdrome. It reviews current knowledge and understanding on the neurochemistry and neuropharmacology of tourettes syndrome
Neuroscientists, psychologists, neurologists
Series Page
Contributors
Preface: The Metamorphoses of Gilles de la Tourette Syndrome
References
Chapter One. An Introduction to the Clinical Phenomenology of Tourette Syndrome
Abstract
1 Basic Nosography of Primary Tic Disorders
2 Phenomenology
References
Chapter Two. Functional Neuroanatomy of Tics
Abstract
1 Introduction
2 Structural Abnormalities
3 Functional Findings
4 Tics—A Matter of Connectivity?
Acknowledgments
References
Chapter Three. Functional Imaging of Dopaminergic Neurotransmission in Tourette Syndrome
Abstract
1 Introduction
2 Imaging of Cerebral Glucose Metabolism and Cerebral Blood Flow
3 Role of Dopaminergic Modulation in TS
4 The Role of Other Neurotransmitter Systems in TS
5 Conclusion
Acknowledgments
References
Chapter Four. Nondopaminergic Neurotransmission in the Pathophysiology of Tourette Syndrome
Abstract
1 Introduction
2 Role of the Monoamines Norepinephrine and Serotonin
3 Role of the Monoamine Histamine
4 Role of Glutamate
5 Role of GABA
6 Role of ACh
7 Role of Endocannabinoid
8 Role of Corticoid
9 Conclusion
References
Chapter Five. Reinforcement Learning and Tourette Syndrome
Abstract
Abbreviations
1 Reinforcement Learning: Concepts, and Paradigms
2 Neural Correlates of Reinforcement Learning
3 Tourette Syndrome and Reinforcement Learning
4 Conclusions and Perspectives
Acknowledgments
References
Chapter Six. Genetic Susceptibility and Neurotransmitters in Tourette Syndrome
Abstract
1 Introduction
2 Neurotransmitter Abnormalities Associated with TS
3 Neurotransmitter-Related Genetic Findings
4 Histamine-Related Genetic Findings
5 Neurotransmitter-Related Gene Expression Studies of Blood
6 Conclusion and Future Studies
References
Chapter Seven. Pharmacological Animal Models of Tic Disorders
Abstract
Abbreviations
1 Introduction
2 Validity Criteria for Developing Animal Models
3 Animal Models of Tic Disorders
4 Concluding Remarks and Future Perspectives
References
Chapter Eight. Animal Models Recapitulating the Multifactorial Origin of Tourette Syndrome
Abstract
1 Tic Disorders and Tourette Syndrome
2 Tourette Syndrome: Etiological Factors
3 Animal Models of TS
4 Future Perspectives
Acknowledgments
References
Chapter Nine. Neuroendocrine Aspects of Tourette Syndrome
Abstract
1 Introduction
2 Sex Steroid Hormones and TS
3 The Stress Response in TS
4 Neurohypophysial Peptides: Possible Players in the Complex Pathophysiology of TS?
5 Conclusions
References
Chapter Ten. Clinical Pharmacology of Dopamine-Modulating Agents in Tourette’s Syndrome
Abstract
1 Introduction
2 DA Receptor Antagonists
3 Systematic Review of Dopamine Receptor Antagonists in the Treatment of TS
4 Tetrabenazine
5 Dopamine Agonists
6 Summary
References
Chapter Eleven. Clinical Pharmacology of Nondopaminergic Drugs in Tourette Syndrome
Abstract
1 Introduction
2 Alpha2 Receptor Agonists
3 GABA Agonists
4 Cannabinoids
5 Botulinum Toxin
6 Tetrabenazine
7 Nicotine
8 Acetylcholinesterase Inhibitors
9 Immunoglobulins, Plasmapheresis, and Antibiotics
10 Summary and Future Research
References
Further-Reading
Chapter Twelve. Antiepileptic Drugs and Tourette Syndrome
Abstract
1 Introduction
2 TS: From Motion to Emotion
3 Pharmacological Treatments for Tics
4 Treatment with AEDs
5 Discussion
Acknowledgments
References
Chapter Thirteen. Clinical Pharmacology of Comorbid Obsessive–Compulsive Disorder in Tourette Syndrome
Abstract
1 Introduction
2 Obsessive–Compulsive Disorder
3 Treatment of Obsessive–Compulsive Disorder
4 Conclusions
References
Chapter Fourteen. Clinical Pharmacology of Comorbid Attention Deficit Hyperactivity Disorder in Tourette Syndrome
Abstract
1 Introduction
2 Diagnosis and Assessment
3 Overview of Therapeutic Interventions
4 Pharmacological Treatment Options
5 Pharmacotherapy Options Can Be Divided into Three Tiers with First-Tier Drugs Considered First-Choice Treatments
6 Adverse Effects
7 Conclusive Remarks
References
Chapter Fifteen. Emerging Treatment Strategies in Tourette Syndrome: What’s in the Pipeline?
Abstract
1 Introduction
2 Potential and Emerging Pharmacological Treatments
3 Potential and Emerging Nonpharmacological Treatments
4 Conclusion
References
Chapter Sixteen. Tics and Other Stereotyped Movements as Side Effects of Pharmacological Treatment
Abstract
1 General Considerations
2 Tics and Stereotyped Movements After Antipsychotic Exposure
3 Secondary Tics After Treatment with Psychostimulants
4 Tics and Stereotyped Movements and Antiepileptic Drugs
References
Index
Contents of Recent Volumes
- No. of pages: 572
- Language: English
- Edition: 1
- Volume: 112
- Published: November 27, 2013
- Imprint: Academic Press
- Hardback ISBN: 9780124115460
- eBook ISBN: 9780124115613
DM
Davide Martino
Affiliations and expertise
South London NHS Trust, UKAC
Andrea E Cavanna
The Barberry National Centre for Mental Health, Birnimingham, UK
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