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Books in Life sciences

  • Basic Principles of Drug Discovery and Development

    • 3rd Edition
    • Benjamin E. Blass
    • English
    Basic Principles of Drug Discovery and Development, Third Edition presents a unique overview of the drug discovery and development program not available elsewhere. Each chapter provides sufficient technical details on the topics covered so that non-experts will have the tools and information necessary to interact and exchange information with colleagues across the entire spectrum of the drug discovery and development process. The drug discovery and development process involves individuals and teams with a wide array of expertise ranging from basic sciences (medicinal chemistry, biology) to applied science (pharmacology, pharmacokinetics, clinical sciences) to business driven fields (regulatory affairs, intellectual property experts, marketing specialists).The success or failure of a program focused on bringing a new medication to market often depends on clear communication between individuals and teams with vastly different expertise. As a result, it is critical that experts in one aspect of drug discovery and development (e.g., medicinal chemists) have a working understanding of the wide range of disciplines that take part in the overall process.

  • Stress: Psychopathology and Psychiatry

    • 1st Edition
    • George Fink
    • English

  • Seldin and Giebisch's The Kidney

    Physiology and Pathophysiology
    • 6th Edition
    • Robert J. Alpern + 3 more
    • English
    Seldin and Giebisch’s The Kidney: Physiology and Pathophysiology, Sixth Edition provides a common language for nephrology researchers, fellows, and practicing nephrologists to discuss normal and abnormal renal physiology and the development and diagnosis of a wide range of renal diseases. Guided by a team of four distinguished authorities in nephrology, experts from all areas of renal research and practice take readers from the structure and function of the normal kidney, to the specific cellular and molecular mechanisms underlying disease development, and into the management of renal disease through physiologic regulation. This classic nephrology reference for nearly 30 years combines basic and clinical sciences that provides authoritative, concise, and readily accessible information. Academic, medical, and pharma researchers save valuable time by quickly accessing the very latest details on renal physiology and pathophysiology as opposed to searching through thousands of journal articles.

  • Retinoic Acids in Cancer Therapy

    Mechanisms of Sensitivity, Resistance, and Methods of Delivery
    • 1st Edition
    • Volume 23
    • Saeid Ghavami + 2 more
    • English
    Retinoic Acids in Cancer Therapy: Mechanisms of Sensitivity, Resistance, and Methods of Delivery provides an overview of how All-Trans Retinoic Acid (ATRA) kills cancer cells and how some cells survive treatment. Focusing on the cellular pathways and compartments involved in ATRA-mediated inhibition of proliferation, this book also discusses how aggressive tumors develop escape routes conferring retinoic acid resistance.Across 15 chapters, it describes the molecular structure and biological properties of ATRA, explains mechanisms of resistance, and defines ATRA’s efficacy in seven cancer types. It concludes with chapters on ATRA and cancer stem cell biology, strategies to improve treatment, future therapeutic perspectives, and delivery methods to reduce toxicity and enhance anticancer efficacy.Each chapter includes Learning Objectives and a “What We Learn” section, making the book highly accessible for undergraduate, graduate trainees, scientists, physicians, and biotech companies. Adding simple, attractive schemes and informative tables makes it ideal for all interested in the current status of Retinoic Acids in Cancer Therapy. This book serves as a valuable resource for health professionals, scientists, researchers, clinical practitioners, and all those seeking to broaden their knowledge and develop new drugs or therapeutic strategies to improve ATRA’s efficacy in the treatment of resistant cancers.

  • Cybersecurity for Healthcare Systems in the Internet of Medical Things Era

    • 1st Edition
    • Janmenjoy Nayak + 2 more
    • English
    Cybersecurity for Healthcare Systems in the Internet of Medical Things Era is driven by the imperative to address the intricate convergence of healthcare, technology, and security. In response to the burgeoning challenges presented by the Internet of Medical Things (IoMT), this book is designed to be an indispensable resource for computer systems experts, healthcare staff, and executives. It goes beyond the surface, offering strategic insights and actionable strategies that encompass not only the IoMT landscape but also the intersection of artificial intelligence, signal processing, and cyber security. Cybersecurity for Healthcare Systems in the IoMT Era serves as a problem-solving compass for a diverse readership in the healthcare landscape. For healthcare professionals and IT leaders, the book untangles the complexities of integrating and securing Internet of Medical Things (IoMT) devices, offering a roadmap for understanding and navigating this rapidly evolving terrain. Biomedical engineers, burdened with strategic and everyday decisions, find in this book strategic insights and actionable strategies, empowering them to make informed choices amidst the ever-changing challenges posed by technology and cybersecurity threats. The authors present a comprehensive guide that not only elucidates the challenges and opportunities presented by IoMT but also explores how the synergy of AI and signal processing can elevate healthcare systems. This integration is crucial in deciphering the intricate nuances of medical data, enhancing diagnostics, and fortifying the security of interconnected healthcare networks.

  • Group B Streptococcus in Pregnancy, Childbirth, and the Neonatal Period

    • 1st Edition
    • Philip Steer + 1 more
    • English
    Group B Streptococcus (GBS) in Pregnancy, Childbirth, and the Neonatal Period brings together field experts to provide a comprehensive understanding of group B streptococcus (GBS), the most common cause of perinatal infection today. It discusses this important bacterium and infection within pregnancy, both obstetric and fetal aspects during labor, and in the infant.The book opens with a global view of GBS, recounting the history and variation in risk factors and outcomes across regions. Subsequent chapters cover not only the biology, epidemiology and pathology, but also intricately describe infection management, treatment, and prevention options. Both early onset as well as late onset GBS disease are discussed.Further, written accounts of lived experiences with varying outcomes are included, along with strategies to aid practitioners in improving care and understanding of babies and families impacted by GBS. The book concludes with clarification of common misconceptions and discussion of future directions in prevention and treatment options. This comprehensive reference offers evidence-based insights aimed at enhancing practice and ultimately improving perinatal outcomes.

  • Laboratory Animal Medicine

    • 4th Edition
    • James G. Fox + 4 more
    • English
    Laboratory Animal Medicine, Fourth Edition—a volume in the American College of Laboratory Animal Medicine (ACLAM) blue book series—is the authoritative reference on the biology, health, and care for species involved in research. Edited by recognized veterinary, operational, and research experts and endorsed as the official material for veterinary specialty certification by ACLAM, this work defines the standard for all aspects of humane laboratory animal care and science with animal models.This new edition contains significant changes in content and organization to reflect the evolution of the field. The animal welfare chapter has been moved to the beginning of the book to highlight this subject’s importance. Other chapters have either been consolidated to encourage the reader to recognize commonalities such as those between guinea pigs, gerbils and hamsters, or separated out in recognition of expansions in knowledge and cross-species complexity as illustrated by separate new and old world primate chapters. Advances in practice, technology, and knowledge are highlighted in the chapters on genetically modified organisms, with updates on new techniques in genetic engineering and consideration of non-rodent genetically modified models; microbiological monitoring, with an increased emphasis on environmental monitoring and sentinel free colony health monitoring methods; regulatory compliance, with a comprehensive chapter on birds; employee health and safety, with expanded consideration of compassion fatigue; and animal models in biomedical research, with increased emphasis on experimental design and rigor. New chapters on animal models for microbiome, infectious disease, and transplant research have been added to serve as a reference for the community.This book is an excellent reference for veterinarians and research scientists, as well as program directors and facility managers employed in a variety of academic and corporate settings. This edition continues the tradition of this text in setting standards for the research animal science community as well as expanding and updating relevant and essential topics for this specialty field.

  • Plant Proteins, Bioactive Peptides, and Healthy Foods

    Nutritional Properties, Functional Applications, and Processing Innovations
    • 1st Edition
    • Zhongjiang Wang + 4 more
    • English
    Plant Proteins, Bioactive Peptides, and Healthy Foods: Nutritional Properties, Functional Applications, and Processing Innovations, offers a comprehensive exploration of emerging and novel plant-based proteins, including soy, pea, walnut, quinoa, hemp, duckweed, oat and more, detailing nutritional properties, bioactive peptide generation, and the potential health benefits they offer for cardiovascular support, muscle recovery, and inflammatory conditions. By analyzing the interactions between proteins and other food components, such as fibers and lipids, the book also highlights the synergies that improve nutrition and digestion. Plant Proteins, Bioactive Peptides, and Healthy Foods: Nutritional Properties, Functional Applications, and Processing Innovations also provides insights into the latest processing technologies, including fermentation and enzymatic hydrolysis, that enhance protein bioavailability. Chapter experts highlight the challenges and opportunities in plant-based utilization including limitations in sensory attributes, processing challenges and allergenicity, strategies for optimizing nutritional quality and functional properties and future directions in research and industrial applications. Sustainable and efficient plant-protein production is also addressed. This book serves as a valuable guide for professionals in the food industry and researchers looking to innovate functional food products and nutraceuticals, contributing to the growing demand for sustainable, plant-based diets.

  • Cutting Edge Advances in Transplantation

    • 1st Edition
    • Dai Dao Nghiem
    • English
    Cutting Edge Advances in Transplantation presents the current state of the science of transplantation. With a unique interdisciplinary approach, this reference collects contributions from selected transplant surgeons, scientists, and immunologists who have worked in the field for the last thirty years. Coverage includes transplantation tolerance, the molecular approach to transplant monitoring, sensitized transplant recipients, xenotransplantation, biologics, and regifted organs. This is the perfect reference for transplant surgeons and nephrologists that want to find new approaches and solutions to serve their patients. It is also ideal for transplantation researchers looking for the most up-to-date scientific information related to the field which can be built upon.

  • Aquaculture Mycology and Bacteriology

    • 1st Edition
    • Frederick S.B. Kibenge + 2 more
    • English
    Aquaculture Mycology and Bacteriology is a practical reference to address the steadily increasing importance of infectious diseases of aquatic animals. With the burgeoning expansion of the animal aquaculture industry to new geographic areas, new microbial and parasitic species with pathogenic potential will continue to emerge. This necessitates rapid identification of the new pathogens to enable their control. Each pathogenic bacterial or fungal species is accompanied by the full description of both taxonomic and clinical information for the three major aquatic food animals (fish, crustaceans and mollusks).Aquacultur... Mycology and Bacteriology takes a comprehensive approach to facilitate research to develop vaccines or other similar pathogen mitigation measures, and is useful to bacteriologists, mycologists, aquaculturists, clinical practitioners in aquatic animal health and all those in industry, government or academia who are interested in aquaculture, fisheries and comparative biology.

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