Extracellular Vesicles from Basic Research to Clinical Applications
- 1st Edition, Volume 94 - October 5, 2024
- Imprint: Academic Press
- Editor: Ana Claudia Torrecilhas
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 2 9 4 9 6 - 9
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 9 4 9 7 - 6
Extracellular Vesicles from Basic Research to Clinical Applications, Volume 94 covers theses lipid bilayer particles containing proteins, glycoproteins, mRNA, other small RNA sp… Read more
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Request a sales quoteExtracellular Vesicles from Basic Research to Clinical Applications, Volume 94 covers theses lipid bilayer particles containing proteins, glycoproteins, mRNA, other small RNA species, and lipids formed and released by various pathogens. Chapters in this update include Extracellular Vesicles release from protozoa parasite and animal model, EVs from parasite and biomarkers, Translational Medicine – Use of EVs as therapy, EVs and viruses and their interaction with cells, EVs and Toxoplasma gondii, EVs and Fungi, Biogenesis of EVs in parasites, Extracellular vesicles, EVs and Leishmania, EVs in neuropsychiatry, EVs and Bacteria.
Other sections cover EVs and sleep deprivation, EVs and cancer, Extracellular vesicles and methods to isolation, purification, and characterization.
Other sections cover EVs and sleep deprivation, EVs and cancer, Extracellular vesicles and methods to isolation, purification, and characterization.
- Provides a comprehensive exploration of extracellular vesicles (EVs) in the context of pathogen-host interactions, shedding light on their role as mediators in communication between hosts and infectious agents
- Presents in-depth discussion on the nature, origin, identification, and characterization of EVs, providing valuable insights into their diverse functions in regulating physiological and pathological processes
Researchers in microbiology and immunology; Clinicians and healthcare professionals specializing in infectious diseases; Graduate students and academics in biological sciences; Biomedical scientists and pharmacologists interested in therapeutic strategies
- Title of Book
- Cover image
- Title page
- Table of Contents
- Series Page
- Copyright
- Contributors
- Preface
- Chapter One: Extracellular vesicles
- Abstract
- 1 Introduction
- 2 The history of EVs
- 3 Subtypes and nomenclatures
- 4 Biogenesis
- 5 Functions
- 6 Applications
- 7 Perspectives and conclusion
- References
- Chapter Two: Extracellular vesicles: Methods for purification and characterization
- Abstract
- 1 Introduction
- 2 Methods for isolation and characterization of EVs
- 3 Techniques of characterization
- 4 Perspectives and conclusion
- References
- Chapter Three: Biogenesis of EVs in Trypanosomatids
- Abstract
- 1 Introduction
- 2 Extracellular Vesicles and Parasite Adaptation to Hosts
- 3 Extracellular Vesicles Biogenesis
- 4 Vesicle Trafficking in Trypanosomatids
- 5 Conclusion and future directions
- Acknowledgments
- References
- Chapter Four: Extracellular vesicles release from protozoa parasite and animal model
- Abstract
- 1 Introduction
- 2 Biodistribution of EVs
- 3 Use of animal models to better understand the role and applications of protozoan parasites EVs
- 4 Conclusions
- 5 Summary
- References
- Chapter Five: Extracellular vesicles in malaria: Pathogenesis, diagnosis and therapy
- Abstract
- 1 Malaria
- 2 Extracellular vesicles
- 3 Extracellular vesicles as new players in malaria pathogenesis
- 4 Therapeutic strategies
- 5 Conclusion remarks
- References
- Chapter Six: Involvement of extracellular vesicles in the interaction of hosts and Toxoplasma gondii
- Abstract
- 1 Introduction
- 2 T. gondii interaction with extracellular vesicles and miRNAs
- 3 Future perspectives: T. gondii-EVs as potential biomarkers for diagnosis, vaccination, and treatment of toxoplasmosis
- References
- Chapter Seven: Extracellular vesicles in parasitic protozoa: Impact of Leishmania exosomes containing Leishmania RNA virus 1 (LRV1) on Leishmania infectivity and disease progression
- Abstract
- 1 Introduction
- 2 Leishmania RNA viruses
- References
- Chapter Eight: Extracellular vesicles as biomarkers in parasitic disease diagnosis
- Abstract
- 1 Introduction
- 2 Protozoa
- 3 Helminths
- 4 Conclusions and future perspectives
- Acknowledgments
- References
- Chapter Nine: Exploring bacterial extracellular vesicles: Focus on WHO critical priority pathogens
- Abstract
- 1 Introduction
- 2 Historical background
- 3 Biogenesis of bacterial extracellular vesicles
- 4 Composition of bacterial extracellular vesicles
- 5 Clinical application of bacterial extracellular vesicles: focus on Acinetobacter baumannii and Klebsiella pneumoniae
- 6 OMV-based vaccine strategies
- 7 Conclusions and perspectives
- References
- Chapter Ten: The role of extracellular vesicles in cancer
- Abstract
- 1 Introduction
- 2 Tumor-derived exosomes biogenesis
- 3 The influence of tumor-derived exosomes on antitumor surveillance
- 4 Extracellular vesicles and epigenetic modifiers in cancer
- 5 The role of extracellular vesicles in tumor progression
- 6 Role of extracellular vesicles in cancer therapy
- 7 Conclusions and future perspectives
- References
- Chapter Eleven: Extracellular vesicles and sleep deprivation
- Abstract
- 1 Introduction
- 2 Sleep deprivation
- 3 Extracellular vesicles and sleep
- 4 Final considerations
- References
- Chapter Twelve: Extracellular vesicles in neurodegenerative, mental, and other neurological disorders: Perspectives into mechanisms, biomarker potential, and therapeutic implications
- Abstract
- 1 Introduction
- 2 Extracellular vesicles in neurodegenerative diseases
- 3 Extracellular vesicles in mental disorders
- 4 Other neurological disorders
- 5 Conclusions and perspectives
- References
- Edition: 1
- Volume: 94
- Published: October 5, 2024
- No. of pages (Hardback): 354
- No. of pages (eBook): 310
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780443294969
- eBook ISBN: 9780443294976
AT
Ana Claudia Torrecilhas
Graduated in Medical Biology from the Faculty of Philosophy, Sciences, and Letters Barão de Mauá (1988), with a master’s degree in Immunogenetics from the Federal University of São Paulo (UNIFESP, 1999) and a Ph.D. in Host-Parasite Relationship Biology from the University of São Paulo (USP, 2004). She completed her postdoctoral research at the Institute of Chemistry at USP (2004-2008) and the University of Georgia, USA (2010-2011). Currently, she is an Associate Professor at UNIFESP, Diadema campus, working in the field of Protozoology of Parasites, focusing on the characterization of Extracellular Vesicles (EVs) and their mechanisms of interaction with the host. She was a board member and part of the scientific committee of the International Society for Extracellular Vesicles (ISEV) from 2016-2020 and 2022-2024. She is an Associate Editor of journals such as Journal of Extracellular Vesicles (JEV), Journal of Extracellular Biology (JEB), Frontiers in Immunology, Frontiers in Cellular and Infection Microbiology, and Brazilian Journal of Health Research (BJHR). Currently, she serves as the Communication Coordinator of ISEV (2024-2026).
Affiliations and expertise
Federal University of São Paulo (UNIFESP, São Paulo, Brazil)Read Extracellular Vesicles from Basic Research to Clinical Applications on ScienceDirect