The Scientific Basis of Mpox (Monkeypox)
Features, Prevention, and Treatments
- 1st Edition - September 30, 2024
- Latest edition
- Editors: Rajkumar Rajendram, Vinood B. Patel, Victor R. Preedy
- Language: English
The Scientific Basis of Monkeypox: Features, Prevention, and Treatments advances understanding of monkeypox and provides a framework for future research with evidence-based and fo… Read more
Description
Description
Chapter contributions are from leading national and international specialists, including those from world renowned institutions who provide a global perspective. The book is a perfect reference for specialists in infectious diseases, virologists, microbiologists, health scientists, public health workers, doctors, pharmacologists, and research scientists.
Key features
Key features
- Summarizes monkeypox using evidenced based ethos
- Provides practical details, recommendations, and suggestions for research, prevention, and treatment: from cells to policy
- Presents forward-thinking application to new and emerging communicable diseases
Readership
Readership
Table of contents
Table of contents
Section 1: Setting the Scene and Introductory Chapters
1. A synopsis of mpox
Heidi M. Torres
2. Monkeypox unveiled: understanding its impact on public health
Professor Dr. Roy Rillera Rillera Marzo
3. Human mpox (monkeypox) virus and its evolution
Jonas Wolf Sr., Lucas Wolf, Ana Paula de Souza, Arthur Pille, Jucara Gasparetto Maccari and Luiz Antonio Nasi
4. Importance of emerging lineages of mpox (monkeypox) virus: an updated narrative
Mayla Abrahim and Alexandro Guterres
5. Bridging borders: the collective fight against monkeypox outbreaks
Professor Dr. Roy Rillera Rillera Marzo
6. Social media and the response to mpox (monkeypox)
David C. Coker
Section 2: The Biology And Transmission Of mpox (monkeypox)
7. Monkeypox virus: fundamental features of its particle, replication cycle, cytopathic effects and research models
Amanda Stéphanie Arantes Witt, Ana Gabriella Stoffella-Dutra, Nidia Esther Colquehuanca Arias, Thalita Souza Arantes, Denilson Eduardo Silva Cunha, Jonatas Abrahao and Giliane de Souza Trindade
8. Biology of the mpox virus and the cysteine protease structures and basis of in silico studies
Hardeep Singh Tuli and Tejveer Singh
9. The serial interval distributions of the mpox virus infection
Shi Zhao, Zihao Guo and Sheikh Taslim Ali
10. Investigating mpox: linking web tools and genomic analysis
José Luis Zambrano Rouvier, Flor H. Pujol, Zoila C. Moros, Carmen L. Loureiro, Rossana C. Jaspe, Yoneira Sulbaran and David S. Coll
11. Mathematical Modelling of Mpox: A Review
Jan Rychtar, Dewey Taylor and Oyita Udiani
Section 3: Detection And Confirmation
12. Development, validation, and use of assays within the clinical diagnostic and Emergency Use Authorization/Food and Drug Administration (EUA/FDA) contexts
Kurt Schaecher
13. Primers and Probes for the Diagnostics of mpox (monkeypox) Virus
Fuqing Wu
14. Monkeypox and wastewater surveillance: tracing the spread of a viral outbreak through environmental monitoring
Giuseppina La Rosa, Elisabetta Suffredini and Marcello Iaconelli
Section 4: Effects On the Body. Tissues And Organs Systems
15. Time related change in skin lesions and their progression
Yeimer Ortiz-Martínez and Andrés F. Henao-Martínez
16. Atypical skin manifestations of mpox
Andrés Grau-Echevarría Sr., R. Penuelas Leal, Carolina Labrandero, Daniel Blaya Imbernón Sr., Malena Finello and Pablo Hernandez Sr.
17. Variations in clinical features and symptoms in mpox (monkeypox) infection: fever and beyond
R. Penuelas Leal, Carolina Labrandero, Andrés Grau-Echevarría Sr., Daniel Blaya Imbernón Sr., Malena Finello and Pablo Hernandez Sr.
18. Otolaryngological features of mpox: lymphadenopathy, pharyngeal and airways
Kaitlyn Aragon Brooks, Nathaniel Neptune and Douglas Mattox
19. Cardiac involvement of mpox (monkeypox)
Ana Isabel Pinho and Marta Braga
Section 5: Vaccinations, Treatments And Alleviation Of Symptomology
20. The psychological responses of mpox (monkeypox) virus vaccination in health care workers: international aspects
Ramy Mohamed Ghazy I, Engy El-Ghitany, Hoda Ali Ahmed Shiba, Safar Abadi Alsaleem Alshahrani, Ehab Elrewany and Dalia El Samhouri
21. Immunoinformatics and mpox (monkeypox) virus vaccines
Budheswar Dehury and Sarbani Mishra
22. Barriers to mass vaccination against monkeypox: an overview
SEMEEH AKINWALE OMOLEKE and Enya Bassey
23. Approved and experimental antivirals for mpox
Bichitra Kumar. Biswal, Swati Kumari and Sonanjali Aneja
24. Repurposing drugs for monkeypox using artificial intelligence
Chiragkumar Patel and Raghvendra Mall
25. Monkey Pox clinical management-A Review
ANIL Kumar SHARMA
26. Treating pustular skin lesions in viral infection: mpox and beyond
Pablo Hernandez Sr., Daniel Blaya Imbernón Sr., Malena Finello, R. Penuelas Leal, Carolina Labrandero
and Andrés Grau-Echevarría Sr.
27. Treating concomitant HIV and mpox virus infection
N.N. Pettit, Aniruddha Hazra, Alison Lew, Renslow Sherer, Sabrina Imam and Elizabeth Bell
Section 6: Case Studies
28. Case Study: Mpox (monkeypox) and a typical scenario of clinical presentation, diagnosis and successful treatment
Almira Opardija
29. Case Study: Heterosexual transmission of mpox
Jesus Sánchez Díaz, Laura Montero Morales, Marcos Alonso García, Araceli Arce Arnáez and Jesus Iñigo Martinez
30. Case Report: Simultaneous presentation of human monkeypox virus and sexually transmited diseases (STDs): a diagnostic and management challenge
Maria J. Vivancos-Gallego
31. Case study: Anatomopathological findings in different mpox cutaneous lesions
Carolina Labrandero, Andrés Grau-Echevarría Sr., R. Penuelas Leal, Daniel Blaya Imbernón Sr., Laura Parra Navarro, Pablo Hernandez Sr. and Victor Alegre de Miquel
32. Case Study: Scaring and quality of life in mpox
Pablo Hernandez Sr.
Section 7: Resources
33. Resources for the study and investigation of mpox (monkeypox)
Rajkumar Rajendram
Product details
Product details
- Edition: 1
- Latest edition
- Published: October 3, 2024
- Language: English
About the editors
About the editors
RR
Rajkumar Rajendram
Dr Rajkumar Rajendram is a clinician-scientist with expertise in internal medicine, anaesthesia, intensive care and peri-operative medicine. He graduated with distinctions from Guy’s, King’s and St Thomas’ Medical School, King’s College London, in 2001, where he received several prizes, merits and distinctions in pre-clinical and clinical subjects.
Dr Rajendram completed specialist training in acute and general medicine in Oxford and subsequently held a Consultant appointment in Acute General Medicine at the John Radcliffe Hospital, Oxford. He also trained in anaesthesia and intensive care in London, including advanced training in regional anaesthesia and intensive care, and subsequently held a Consultant appointment in Intensive Care, Anaesthesia and Peri-operative Medicine at the Royal Free London Hospitals.
His postgraduate training has spanned internal medicine, anaesthesia, intensive care and point-of-care ultrasound (POCUS). He was awarded Fellowship of the Royal College of Anaesthetists in 2009, Fellowship of the Faculty of Intensive Care Medicine in 2013, and the European Diploma in Intensive Care Medicine in 2014. He is a Fellow of both the Royal College of Physicians of Edinburgh and the Royal College of Physicians of London.
Dr Rajendram is currently a Consultant at King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia, and holds a joint appointment as Associate Professor in the Research Unit, Department of Medical Education, at King Saud bin Abdulaziz University for Health Sciences.
His multidisciplinary clinical background has informed his research interests in nutrition, fluid management and fluid balance in health and disease, particularly in acutely and critically ill patients. His research has also addressed POCUS, COVID-19 phenotypes and nutritional support in illness. Dr Rajendram has contributed extensively to medical research and education and has authored more than 400 textbook chapters, review articles, peer-reviewed papers and conference abstracts.
VP
Vinood B. Patel
Vinood B. Patel, BSc, PhD, FRSC, is Professor in Clinical Biochemistry at the University of Westminster. In 2014 Dr Patel was elected as a Fellow to The Royal Society of Chemistry. Dr Patel graduated from the University of Portsmouth with a degree in Pharmacology and completed his PhD in protein metabolism from King’s College London in 1997. His postdoctoral work was carried out at Wake Forest University Baptist Medical School, NC, USA studying structural-functional alterations to mitochondrial ribosomes, where he developed novel techniques to characterize their biophysical properties. Research is being undertaken to study the role of nutrients, antioxidants, phytochemicals, iron, alcohol and fatty acids in the pathophysiology of disease. Other areas of interest are identifying new biomarkers that can be used for the diagnosis and prognosis of disease and understanding mitochondrial oxidative stress. Dr Patel is a nationally and internationally recognized researcher and has several edited biomedical books related to health and well being These books include Ancient and traditional foods, plants and herbs and spices in human health; coffee in health and disease prevention, Nuts and seeds in health and disease prevention Handbook of Substance Misuse and Addictions: From Biology to Public Health, tea in health and disease prevention.
VP
Victor R. Preedy
Victor R. Preedy, BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC, FRSM, is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He also holds an Honorary Professorship at the University of Suffolk and served as the long‑term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy graduated with an Honours Degree in Biology and Physiology with Pharmacology and later obtained his PhD from the University of London. He subsequently received Membership of the Royal College of Pathologists and later earned his second doctorate (DSc) in recognition of his contributions to protein metabolism. He is a Fellow of the Royal Society of Medicine, the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health and Hygiene, the Royal Society for Public Health, and the Royal Society of Chemistry. Professor Preedy has conducted research while affiliated with Imperial College London, the School of Pharmacy (now part of University College London), and the MRC Centre at Northwick Park Hospital. He has collaborated widely with international research groups in Finland, Japan, Australia, the USA, and Germany. His longstanding academic interests include health and well‑being. He has published more than 750 works, including peer‑reviewed research articles, abstracts, symposium presentations, reviews, and edited books.