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Books in Life sciences

  • Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy

    • 3rd Edition
    • Herbert B. Newton
    • English
    Handbook of Brain Tumor Chemotherapy, Molecular Therapies, and Immunotherapy, Third Edition offers a unique cutting-edge collection of basic science and clinical information brain tumor chemotherapy research. The book represents the most complete single-volume resource available for information on the subject of brain tumor chemotherapy. Including a multidisciplinary approach, this volume combines recent advances tumor therapy with molecular biology, molecular therapeutics, immunobiology, and immunotherapy approaches in one location. Chapters new to this volume include cutting-edge research on the molecular underpinnings of brain tumors such as glioblastoma, other gliomas, and targeted molecular therapies to consider for treatment.

  • Neurobiology and Artificial Intelligence

    Medical, Social and Ethical Implications
    • 1st Edition
    • Luca Saba
    • English
    Neurobiology and Artificial Intelligence: Medical, Social, and Ethical Implications explores the dynamic intersection of neurobiology and artificial intelligence, investigating the scientific, philosophical, and ethical implications of these rapidly evolving fields. By blending cutting-edge research with thought-provoking discussions, the book aims to make complex topics accessible to an interdisciplinary audience, from researchers and upper graduate students eager to understand how AI and neuroscience shape our understanding of intelligence, creativity, learning, and the human condition.

  • Group B Streptococcus in Pregnancy, Childbirth, and the Neonatal Period

    • 1st Edition
    • Philip Steer + 1 more
    • English
    Group B Streptococcus (GBS) in Pregnancy, Childbirth, and the Neonatal Period brings together field experts to provide a comprehensive understanding of group B streptococcus (GBS), the most common cause of perinatal infection today. It discusses this important bacterium and infection within pregnancy, both obstetric and fetal aspects during labor, and in the infant.The book opens with a global view of GBS, recounting the history and variation in risk factors and outcomes across regions. Subsequent chapters cover not only the biology, epidemiology and pathology, but also intricately describe infection management, treatment, and prevention options. Both early onset as well as late onset GBS disease are discussed.Further, written accounts of lived experiences with varying outcomes are included, along with strategies to aid practitioners in improving care and understanding of babies and families impacted by GBS. The book concludes with clarification of common misconceptions and discussion of future directions in prevention and treatment options. This comprehensive reference offers evidence-based insights aimed at enhancing practice and ultimately improving perinatal outcomes.

  • Animal Models of Disease Part E

    • 1st Edition
    • Volume 203
    • English
    Animal Models of Disease, Part E, Volume 203 in the Methods in Cell Biology series, presents significant advancements in understanding disease mechanisms through animal models. The book features chapters on timely topics such as characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors and using zebrafish to unravel the molecular mechanisms of Alzheimer’s disease. The book also covers colitis mouse models and appropriate models for studying diabetes pathophysiology, demonstrating its comprehensive approach to current research.Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.

  • The Resistance of Cervical Cancer to Chemotherapy and its Reversal

    • 1st Edition
    • Volume 9
    • S. Muthusami
    • English
    The Resistance of Cervical Cancer to Chemotherapy and its Reversal provides a holistic understanding of cervical cancer development, immune-evading mechanisms of HPV, immunotherapies available, methods to study cervical cancer and the development of newer drugs. Content shows the involvement of signaling pathways during chemoresistance in cervical cancer, the involvement of genes in drug resistance, and introduces long noncoding RNAs as novel biomarkers.In 10 chapters, this book first provides an introduction and history of cervical cancer; next, it discusses the influence of viruses on cervical cancer and finally, it describes therapies to overcome chemotherapy resistance in cervical cancer. This is the perfect reference to provide the fundamental base of knowledge needed for oncologists, pharmacologists, translational investigators, immunotherapists, scientists, and clinicians interested in building a comprehensive understanding of the field.

  • Lateral Flow Assays for Rapid Point-of-care Testing

    Recent Advances, Emerging Trends, and Future Direction
    • 1st Edition
    • Seema Nara + 2 more
    • English
    The emergence and re-emergence of new infectious diseases places emphasis on the need for greater investment in rapid healthcare diagnostic solutions. As a result, lateral flow immunoassay technology is quickly evolving with new inventions. Lateral Flow Assay for Rapid Point-of-Care Testing covers today’s most significant advancements, emerging trends, and future directions linked with this technology. The book begins with a review of the format, flow, and design of old-generation lateral flow assays and the challenges impeding performance before moving into innovation in materials for rapid test strips, advances in manipulating sample flow, and the latest developments in molecular imprinting and bioconjugation techniques. Subsequent sections cover various biorecognition elements and review signal amplification as well as quantification trends. Final chapters delve into recent applications for infectious diseases detection, monitoring antibiotic resistance, multiplex detection of analytes, as well as future directions leading to the next generation of healthcare. Academicians, researchers, industrialists, and device manufacturers linked to the development of rapid and affordable point-of-care immunodiagnostics will find value in this resource.

  • Basic Microbiology

    History, Fundamentals and Insights
    • 1st Edition
    • Saurabh Bhatia + 2 more
    • English
    Basic Microbiology: History, Fundamentals and Insights offers an exploration of the microbiology, providing a foundation in the study of microorganisms and their impact on health and disease. Beginning with an introduction to microbiology, the book covers the metabolism of microorganisms, revealing the biochemical processes that sustain microbial life. It then examines microbial genetics, uncovering the mechanisms of genetic variation and inheritance in microbes. Detailed chapters on bacteria, fungi, viruses, and protozoa provide thorough insights into the structure, function, and classification of these diverse organisms. The book also covers the principles of immunity, explaining the body’s defense mechanisms against microbial invasion. Finally, it addresses infection and diseases, highlighting the relationship between pathogens and human health. Ideal for students, educators, and professionals in microbiology and related field, Basic Microbiology: History, Fundamentals and Insights serves as an essential resource for understanding the microscopic world and its relevance to medicine and biology.

  • Vaccinology and Immunizations

    • 1st Edition
    • Jahangir Moini + 2 more
    • English
    Vaccinology and Immunizations is a thorough resource on the immune system, the history of vaccines, vaccine preparation, the process of vaccine approval, and the prevention and eradication of diseases. It also includes chapters on vaccine safety and errors, and complete information on pediatric and adult immunizations. There is also discussion on elderly immunology and immunization for people who are seeking to travel abroad, as well as timely information about COVID-19.Its focus on the innate and adaptive defense systems of the body will ensure understanding of human immunity and how immunizations are effective. There is a variety of available titles related to vaccinology and immunizations, but many are now outdated. Vaccinology and Immunizations provides a new, updated resource that is widely needed, and will be welcomed by students of undergraduate, graduate and master level in vaccinology or immunology, and would also be of interest to nurses, researchers, and pharmacists.

  • Basic Principles of Drug Discovery and Development

    • 3rd Edition
    • Benjamin E. Blass
    • English
    Basic Principles of Drug Discovery and Development, Third Edition presents a unique overview of the drug discovery and development program not available elsewhere. Each chapter provides sufficient technical details on the topics covered so that non-experts will have the tools and information necessary to interact and exchange information with colleagues across the entire spectrum of the drug discovery and development process. The drug discovery and development process involves individuals and teams with a wide array of expertise ranging from basic sciences (medicinal chemistry, biology) to applied science (pharmacology, pharmacokinetics, clinical sciences) to business driven fields (regulatory affairs, intellectual property experts, marketing specialists).The success or failure of a program focused on bringing a new medication to market often depends on clear communication between individuals and teams with vastly different expertise. As a result, it is critical that experts in one aspect of drug discovery and development (e.g., medicinal chemists) have a working understanding of the wide range of disciplines that take part in the overall process.

  • Stress: Psychopathology and Psychiatry

    • 1st Edition
    • George Fink
    • English

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