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Elsevier

Books in Life sciences

  • Microbiome and the Eye

    What's the Connection?
    • 1st Edition
    • Anat Galor + 1 more
    • English
    Microbiome and the Eye: What’s the connection? highlights how alterations in the gut and eye microbiomes can lead to systemic immune alterations with subsequent effects on the eye. The book is divided into two sections, one highlighting how alterations in the gut microbiome impact various components of health outside the gut, with a focus on the immune system and inflammatory mediators, and the second focusing on studies on a variety of ocular diseases, including ocular surface diseases/dry eye, keratitis, uveitis, glaucoma, and retinopathy to gut dysbiosis. With its translational approach, the book is suitable for both researchers and clinicians. The book will help readers understand the mechanisms in which gut and eye microbiome composition may influence health in multiple compartments, with a focus on eye diseases.

  • Handbook of Gastrointestinal Motility and Disorders of Gut-Brain Interactions

    • 2nd Edition
    • Satish S.C. Rao + 2 more
    • English
    Handbook of Gastrointestinal Motility and Disorders of Gut-Brain Interactions, Second Edition fills the void in GI literature for a short and concise go-to book for disorders of GI motility and gut and brain interactions. This exceptionally illustrated reference contains all the information needed for the latest knowledge on adults as well as adolescent and pediatric GI motility disorders, each systematically arranged by disorder and gut anatomy for easy reference. Each chapter includes extensive color pictures of each test as well as descriptions of how to perform and interpret the motility tests and how to incorporate them into patient care decisions. Current advances in the field have led the way for new updates. A new section dedicated to systemic disorders and special topics, including gut autonomic disorders, cannabis and the gut, eating disorders, pediatric and adolescent disorders, nutritional therapies, and psychological management is included. This is the perfect book for those who encounter the common problems of dysphagia, heartburn, nausea, vomiting, gastroparesis, abdominal pain, gas and bloating, irritable bowel syndrome, constipation, and fecal incontinence and rare disorders in daily practice, including practicing physicians, gastroenterologists, motility laboratory personnel, surgeons and internists

  • Hormonal Cross-Talk, Plant Defense and Development

    Plant Biology, Sustainability and Climate Change
    • 1st Edition
    • Azamal Husen + 1 more
    • English
    Hormonal Cross-Talk, Plant Defense and Development: Plant Biology, Sustainability and Climate Change focuses specifically on plants and their interaction to auxins, gibberellins, cytokinins, ethylene, abscisic acid, jasmonates, brassinosteroids, strigolactones, and the potential those interactions offer for improved plant health and production. Plant hormones (auxins, gibberellins, cytokinins, ethylene, abscisic acid, jasmonates, brassinosteroids, salicylic acid, strigolactones etc.) regulate numerous aspects of plant growth and developmental processes. Each hormone initiates a specific molecular pathway, with each pathway integrated in a complex network of synergistic, antagonistic and additive interactions. This is a valuable reference for those seeking to understand and improve plant health using natural processes. The cross-talks of auxins - abscisic acid, auxins - brassinosteroids, brassinosteroids- abscisic acid, ethylene - abscisic acid, brassinosteroids - ethylene, cytokinins - abscisic acid, brassinosteroids - jasmonates, brassinosteroids - salicylic acid, and gibberellins - jasmonates - strigolactones have been shown to regulate a number of biological processes in plant system. The cross-talk provides robustness to the plant immune system but also drives specificity of induced defense responses against the plethora of biotic and abiotic interactions.

  • Material-Microbes Interactions

    Environmental Biotechnological Perspective
    • 1st Edition
    • Nabin Aryal + 3 more
    • English
    Material-Microbes Interactions: Environmental Biotechnological Perspective brings great insights into microbes-material interactions, biofilm formation and emerging bioprocesses within the field of applied biotechnology. The book systematically summarizes the fundamental principles, the state-of-the-art in microbes-material interaction, and its application in bioprocess and environmental technology development. Understanding the fundamental processes of biofilm formation, the role of material to exchange the energy with microbes, biofilm matrix, and optimization of the biofilm formation process is useful to everyone involved with bioprocess development. This book will be of significant interest to environmental technology developers, researchers, university professors, policymakers, graduate and postgraduate students and other stakeholders. Interestingly, academic institutions, wastewater treatment plants and research centers have upscaled biofilm-based environmental technologies, such as moving bed bioreactors, microalgae, tricking bed reactors, biofilters, and bioelectrochemical process as promising environmental technologies.

  • Spontaneous Pathology of the Laboratory Non-human Primate

    • 1st Edition
    • Alys Bradley + 2 more
    • English
    Spontaneous Pathology of the Laboratory Non-human Primate serves as a "go to" resource for all pathologists working on primates in safety assessment studies. In addition, it helps diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathologies when assigning cause of death to species in zoological collections. Primate species included are rhesus, cynomolgus macaques and marmosets. Multi-authored chapters are arranged by organ system, thus providing the necessary information for continued research.Pathologist... often face a lack of suitable reference materials or historical data to determine if pathologic changes they are observing in monkeys are spontaneous or a consequence of other treatments or factors.

  • Nonlinear Dynamics of Parkinson’s Disease and the Basal Ganglia-Thalamic-Cortical System

    • 1st Edition
    • Erwin B. Montgomery Jr. + 1 more
    • English
    Nonlinear Dynamics of Parkinson’s Disease and the Basal Ganglia-Thalamic-Cor... System examines current research regarding the operations of the basal ganglia-thalamic-cor... system that causes neurological disorders like Parkinson’s disease. While there have been remarkable advances in the understanding of the anatomy, physiology and chemistry of these systems, there remains a significant degree of inconsistency and incompleteness between facts and advancements. This book introduces the novel concepts of nonlinear complex systems and their connection to Parkinsonism as well as hyperkinetic disorders. The actual mechanisms underlying the motor disorders of Parkinson’s disease at the level of the lower motor neuron are also discussed.

  • Sustainable Development and Pathways for Food Ecosystems

    Integration and Synergies
    • 1st Edition
    • Riccardo Accorsi + 1 more
    • English
    Sustainable Development and Pathways for Food Ecosystems: Integration and Synergies is a science-based reference which explores the roles played by agri-food ecosystems, their functions and needs, and the importance of the interdependencies among them. This book explores the relationships between food ecosystems, highlighting each entity’s role in transforming, preserving, and conserving the others. It is a vital resource of information on the ecosystems that surround the food supply chain and includes all processes, from primary production of food through consumption. The book covers the agricultural and farming phases; processing and transformation; storage and consolidation; packaging; transportation; the management of waste and losses; and the supply and conservation of enabling resources like materials, biodiversity, energy, and water. Sustainable Development and Pathways for Food Ecosystems: Integration and Synergies is a useful reference for academics, researchers, policymakers, and industry professionals involved within the agri-food sector management.

  • Navigating Non-coding RNA

    From Biogenesis to Therapeutic Application
    • 1st Edition
    • Joanna Sztuba-Solinska
    • English
    Navigating Non-coding RNA: From Biogenesis to Therapeutic Application provides a concise overview of the field of non-coding RNA (ncRNA). Chapters cover the history of discoveries that have occurred in the area of ncRNA, specific types of ncRNA, housekeeping ncRNAs such as ribosomal RNA, transfer RNA, small nuclear RNA and telomerase RNA, regulatory ncRNAs such as microRNA, small interfering RNA, long non-coding RNA and Y RNA. Biogenesis, structure, function, and regulation of each of these are also explored in addition to traditional and cutting-edge methods for the identification, functional characterization and structural characterization of ncRNA. The book also focuses on the different types of epitranscriptomic modifications and their involvement in regulating ncRNA structure, stability and intermolecular interactions in addition to the role of ncRNAs in a range of diseases and potential therapeutic applications.

  • The Teeth of Non-mammalian Vertebrates

    Form, Function, Development and Growth
    • 2nd Edition
    • Barry Berkovitz + 1 more
    • English
    The Teeth of Non-Mammalian Vertebrates: Form, Function, Development and Growth, Second Edition is devoted to the teeth and dentitions of living fishes, amphibians, and reptiles. This book presents a comprehensive survey of the wide variety of tooth forms among non-mammalian vertebrates, based on descriptions of approximately 450 species belonging to about 170 families.This latest edition discusses the functional morphology of feeding, the attachment of teeth, and the relationship of tooth form to function, with each chapter accompanied by a comprehensive, up-to-date reference list. Following the descriptions of the teeth and dentitions in each class, four chapters review current topics with considerable research activity: tooth development; tooth replacement; and the structure, formation, and evolution of the dental hard tissues. The Teeth of Non-Mammalian Vertebrates: Form, Function, Development and Growth, Second Edition is authored by internationally recognized teachers and researchers in the field. This new edition reflects the resurgence of interest in the dentitions of non-mammalian vertebrates as experimental systems to help understand genetic changes in evolution of teeth and jaws.

  • Neuroimaging in Neurogenic Communication Disorders

    • 1st Edition
    • Kostas Konstantopoulos + 1 more
    • English
    Neuroimaging in Neurogenic Communication Disorders provides a comprehensive review of cases utilizing neuroimaging in neurogenic communication disorders. Basic knowledge of neuroanatomy and medical conditions related to these speech and language disorders are discussed. Each case study includes information on neuroanatomy, case presentation, neuroimaging, differential diagnosis, and final diagnosis. This book is written for medical students, practitioners and researchers in neuroscience and speech language pathology. Neurogenic communication disorders are caused by damage to the central or peripheral nervous system. This damage can be caused by Parkinson’s disease, stroke, dementia, traumatic brain injury, brain tumors, and other neurologic disorders and causes issues such as aphasia, dysarthria and apraxia.

  • Translational Neuroimmunology, Volume 8

    Multiple Sclerosis
    • 1st Edition
    • Nima Rezaei + 1 more
    • English
    Translational Neuroimmunology: Multiple Sclerosis provides an update on bench to bedside studies on Multiple Sclerosis as an autoimmune disease. Divided into twelve chapters, the book begins with an in-depth introduction to the neuroimmunology and immunopathology of multiple sclerosis. Sections also provide content on genetics and epigenetics, the microbiome, diagnosis, and treatment of multiple sclerosis. Finally, various precision treatments are covered. All information is presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research.

  • Translational Neuroimmunology, Volume 7

    Neuroinflammation
    • 1st Edition
    • Nima Rezaei + 1 more
    • English
    Translational NeuroImmunology: Neuroinflammation updates on bench to bedside studies on neurological disorders that have immunological etiologies. The book covers neuroimmunology and the principles of autoimmune and autoinflammatory neurological disorders, with multiple sclerosis as the main focus. The immunopathology, genetics and epigenetics, microbiome, diagnosis and treatment of multiple sclerosis will be explained in ten chapters. A chapter also examines distinct aspects of pericytes, with final discussions on the neurologic manifestations, diagnostic approaches and treatments of the various neuroimmune disorders and lessons learned from translational research on non-human primates and zebrafish. All sections are presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research.

  • Genetic Steroid Disorders

    • 2nd Edition
    • Maria I. New + 8 more
    • English
    Genetic Steroid Disorders, Second Edition targets adult and pediatric endocrinologists, clinical geneticists, genetic counselors, reproductive endocrinologists, neonatologists, urologists, and psychoendocrinologis... It is designed to assist these specialists in the diagnosis and treatment of steroid disorders. This revision includes a new chapter on "Gonadotropins, Obesity and Bone" and new research on non-invasive prenatal diagnosis with cell-free DNA. Chapters are thoroughly updated covering steroid disorders, the genetic bases for the disorder and case presentations, This definitive reference belongs in every medical library!

  • Laboratory Methods in Microbiology and Molecular Biology

    Methods in Molecular Microbiology
    • 1st Edition
    • Richa Salwan + 1 more
    • English
    Laboratory Methods in Microbiology and Molecular Biology describes various microbiological, biochemical, and molecular methods employed for the characterization, identification, and analysis of actinomycetes, bacteria and fungi. The book details general guidelines, expectations, and responsibilities for good lab practices and consists of chapters that covers basic microbiological, physiological, biochemical, and molecular aspects as well as in silico analysis using various bioinformatic tools. Other topics in the book include how to make solutions, microscopy and imaging of microorganisms, sero-diagnostics, and basic concepts of phylogeny, physiology, biotechnology, soil, food, and environmental microbiology while working in laboratory. Laboratory Methods in Microbiology and Molecular Biology is an informative update to current practices and future perspectives for the field of microbial biotechnology. It aims to facilitate professors, researchers, and graduate students in monitoring the precision and accuracy of the qualitative and quantitative methods in their research.

  • Pharmacogenomics

    From Discovery to Clinical Implementation
    • 1st Edition
    • Showkat Ahmad Ganie + 3 more
    • English
    Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area. The book's chapters over the foundational aspects of pharmacogenomics, including drug metabolism, drug discovery, development, and testing, and then detail studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, psychiatric disease, cancer, pulmonary and respiratory diseases, viral diseases, gastroenterology, autoimmune diseases, immunosuppressants, and, finally, an overview of computational resources. This is the perfect resource for pharmaceutical science graduate students to learn the key concepts of the area. However, researchers and graduate students in the related fields of genetics, pharmacoepidemiology... molecular biology, and medicinal chemistry will also benefit from the structured approach of the book.

  • The Produce Contamination Problem

    Causes and Solutions
    • 3rd Edition
    • Karl Matthews + 1 more
    • English
    The Produce Contamination Problem: Causes and Solutions, Third Edition is a fully revised resource on preventative controls at all stages of handling, including the use of new technologies for the inactivation of pathogens in both water and commodity. The book begins with an analysis of the contamination problem to identify novel research designed to understand the interaction of human pathogens. Outbreak characteristics vulnerable to contamination are discussed, along with global issues surrounding production. This new edition includes updates on regulatory issues and the newest advances in technologies for the detection of pathogens, whole genome sequencing, and utility in test and hold programs.

  • Mechanisms of Morphogenesis

    • 3rd Edition
    • Jamie A. Davies
    • English
    Mechanisms of Morphogenesis, Third Edition offers a bottom-up discussion of mechanisms of cell and tissue morphogenesis in a diverse array of organisms, including prokaryotes, animals, plants and fungi. Across foundational, applied and methods-based chapters, this book examines molecular nano-machines cooperation, generate cell shape, direct cell migration, and shape, form and rates of growth of various tissues in the body. Each topic is illustrated with experimental data from real systems, with particular reference to gaps in current knowledge and likely future developments, along with strategies to apply basic morphogenesis science across ever evolving applications. Newly added chapters feature case-study-driven discussions of morphogenesis in natural embryos and organoids, and illustrate how pathological morphogenesis can generate variants of body form. This edition has also been updated with analysis of large-scale and scale-invariant mechanisms, for example, morphogenesis by differential growth in mechanically connected tissues.

  • Microbial Biofilms

    Challenges and Advances in Metabolomic Study
    • 1st Edition
    • Sanket Joshi + 3 more
    • English
    Microbial Biofilms: Challenges and Advances in Metabolomic Study is a volume in the Advances in Biotechnology and Bioengineering Series. The volume covers the metabolomic characteristics of bacterial biofilms and examines the techniques used in the analysis of the metabolomics of the biofilm, its formation, and related infections. The book includes the metabolomics study of various types of biofilms and details new strategies in targeting metabolic pathways for inhibiting the biofilm. The book also describes various types of metabolomics studies like metabolomics of oral biofilm and metabolomics of biofilm by nosocomial microbes. It also points out the recent advancements on various aspects of metabolomics studies pertaining to biofilms, related infections, their pathogenesis, and present-day treatment strategies. Microbial Biofilms: Challenges and Advances in Metabolomic Study is a helpful resource to scientists and researchers engaged in biofilm studies, precisely on the metabolomic changes at molecular level occurring in the participating microorganisms. It is also fascinating and thought provoking for the clinicians and health professionals actively involved in the treatment of biofilm mediated chronic infections, since it depicts the pathogenic consequences of the small molecular interactions of the metabolites in biofilm.

  • Cognitive Archaeology, Body Cognition, and the Evolution of Visuospatial Perception

    • 1st Edition
    • Emiliano Bruner
    • English
    Cognitive Archaeology, Body Cognition, and the Evolution of Visuospatial Perception offers a multidisciplinary and comprehensive perspective on the evolution of the visuospatial ability in the human genus. It presents current topics in cognitive sciences and prehistoric archaeology, to provide a bridge between evolutionary anthropology and neurobiology. This book explores how body perception and spatial sensing may have evolved in humans, as to enhance a “prosthetic capacity” able to integrate the brain, body, and technological elements into a single functional system. It includes chapters on touch and haptics, peripersonal space, parietal lobe evolution, somatosensory integration, neuroarchaeology, visual behavior, attention, and psychometrics. Cognitive Archaeology, Body Cognition, and the Evolution of Visuospatial Perception represents an essential resource for evolutionary biologists, anthropologists, archaeologists, and neuroscientists who are interested in the role of body perception and spatial ability in human cognition.

  • Handbook of Food and Feed from Microalgae

    Production, Application, Regulation, and Sustainability
    • 1st Edition
    • Eduardo Jacob-Lopes + 3 more
    • English
    Approx.648 pages

  • Macrophomina Phaseolina

    Ecobiology, Pathology and Management
    • 1st Edition
    • Pankaj Kumar + 1 more
    • English
    Macrophomina Phaseolina: Ecobiology, Pathology and Management provides insights into the sustainable prevention and treatment of this wide-spread challenge to plant health. With a focus on agricultural as well as non-food plant challenges, the book highlights diverse approaches and provides central insights. The pathogen of M. phaseolina affects the fibrovascular system of roots and basal internodes of its host, impeding the transport of water and nutrients to the upper parts of the plant, thus resulting in progressive wilting, premature drying and dying, loss of vigor, and reduced yield. Finally, the book explores the interaction of M. phaseolina with soil, microbes and ecological conditions to control disease-causing strategies. Recognizing the necessity that strategies applied to manage the disease should have no or minimum effect on ecological resources, the book focuses on alternative sustainable management technologies such as mix-cropping, the use of antagonistic bacteria and fungi and microbial biosurfactants, plant growth promoting antagonistic rhizobacteria and how cultural practices may also play an important role.

  • Multifaceted Role of IL-1 in Cancer and Inflammation

    • 1st Edition
    • Manisha Singh
    • English
    Multifaceted Role of IL-1 in Cancer and Inflammation summarizes the existing literature and discusses future perspectives about the role of IL-1 in immune suppression, cancer progression, angiogenesis, and resistance to immunotherapies. The book presents mechanisms to overcome IL-1 mediated immune suppression in tumor microenvironment and covers topics on the source of IL-1 in the tumor microenvironment, IL-1 mediated downstream pathway, mechanism of IL-1 mediated immune suppression in cancer, and its effect on immunotherapy of cancer. Those topics help readers understand the effect of IL-1 on cancer immunopathology and immunotherapy, and provide them with broader concepts to develop therapies for IL-1 enrichment tumors. This is a valuable source for cancer researchers, clinicians and other members of the biomedical field who wants to learn more about mechanisms to improve outcome of cancer immunotherapies.

  • Treatments, Nutraceuticals, Supplements, and Herbal Medicine in Neurological Disorders

    • 1st Edition
    • Colin R. Martin + 2 more
    • English
    Treatments, Nutraceuticals, Supplements and Herbal Medicine in Neurological Disorders offers readers a comprehensive reference on their potential for treatment in a wide variety of neurological diseases. Spanning various types of these compounds, this broad coverage allows readers to learn about the use of nutraceuticals and botanicals alone, or in combination with, other dietary regimes and/or vitamins and minerals. It covers diseases including Alzheimer’s, Parkinson’s, ALS and MS, and severe neurological conditions including brain injury, stroke, headache and migraine. This volume provides a platform for research on nutraceuticals and botanical agents and on future investigations of these compounds. There are over 600 neurological disorders affecting both the central and peripheral nervous systems, some of which have been treated by nutraceuticals and herbal medicine, hence this is a timely resource on the topics covered.

  • Diet and Nutrition in Neurological Disorders

    • 1st Edition
    • Colin R. Martin + 2 more
    • English
    Diet and Nutrition in Neurological Disorders offers readers a comprehensive reference on the effect of dietary regimes in a wide variety of neurological diseases. With coverage of different types of diets, including Mediterranean or DASH, this broad coverage allows readers to learn about diets and their affect on specific disorders which may well be relevant to other conditions. This includes diseases such as Alzheimer’s, Parkinson’s, ALS, MS and severe neurological conditions such as brain injury, stroke, headache and migraine. This volume provides a platform for research on new dietary regimes and on future investigations of diet and nutrition.

  • Neurophysiology of Silence Part A: Empirical Studies

    • 1st Edition
    • Volume 277
    • English
    Neurophysiology of Silence, Volume 277 in the Progress in Brain Research series, highlights new advances in the field, including chapters on Mindfulness, mind wandering and creativity, The cloud of unknowing: Cognitive dedifferentiation in whole-body perceptual deprivation, Embodying abstract concepts: the connection between meditation, empathy and introception, Measures of music-like experience emergent in a sonic ganzfeld: an example of perceptual structuring on the edge of silence, Doing out of silence: The effects of visual art on verbal creativity, Cessation experiences during meditation, The psychophysiology of covert behavior during goal directed behavior, and much more.

  • Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders

    • 1st Edition
    • Heba Mohamed Mansour + 2 more
    • English
    Overexpression of receptor tyrosine kinases (RTKs) has been implicated in cancer. Increasing evidence suggests that dysregulation of RTKs is reported in many neurodegenerative and psychiatric disorders. Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders provides a fundamental, pragmatic map of RTKs structure, activation, functions, mechanism of action, gene regulation, and signaling pathways in developing central nervous system (CNS), adult normal CNS, neurodegenerative and psychiatric disorders. Additionally, the structure, function, activation, and therapeutic potential of many growth factors have been covered. Here, international experts in the field offer a comprehensive discussion of results of pre-clinical and clinical studies of repositioning of anti-cancer receptor tyrosine kinase inhibitors (RTKIs) and other promising protein kinase inhibitors in various neurodegenerative disorders including, Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis, and psychiatric disorders including, anxiety, depression, alcohol use disorder, and schizophrenia. In addition, the book discusses the obstacles and opportunities for the potential repositioning of kinase inhibitors in neurodegenerative and psychiatric disorders.

  • Vitamins and Minerals in Neurological Disorders

    • 1st Edition
    • Colin R. Martin + 2 more
    • English
    **Selected for 2026 Doody's Core Titles in Nutrition**Vitamins and Minerals in Neurological Disorders offers readers a comprehensive reference addressing their relationship to brain health in a wide variety of neurological diseases. Examining various compounds, this broad coverage allows readers to learn about the role nutrient deficiency plays in the pathology of many conditions, as well as their potential in treatment. The book covers diseases including Alzheimer’s, Parkinson’s, ALS, and MS, along with severe neurological conditions like brain injury, stroke, headache and migraine. This volume provides a platform for research on vitamins, minerals and future investigations of these compounds.

  • Cases in Laboratory Genetics and Genomics (LGG) Practice

    • 1st Edition
    • Xia Li
    • English
    Cases in Laboratory Genetics and Genomics (LGG) Practice instructs readers in the lab-based diagnosis of genetic conditions, including inborn and acquired disorders using cytogenetics and molecular genetics technologies. This entirely case-based book covers a wide range of genetic cases, from prenatal to postnatal and oncology genetic disorders which lab professionals and geneticists encounter daily in the diagnostic field. Each disorder discussed includes a section on clinical background, clinical indication, tests ordered, laboratory tests performed, test results, results with interpretations, future testing and recommendations, and references. The book will help lab professionals understand and navigate clinical cases using an integrative approach, and thoroughly understand the methodologies and interpretations involved in high complexity genetic testing.

  • Cannabis Use, Neurobiology, Psychology, and Treatment

    • 1st Edition
    • Colin R. Martin + 2 more
    • English
    Cannabis Use, Neurobiology, Psychology, and Treatment offers readers a comprehensive reference on neurological changes, both transient and long-term, and other factors surrounding the use of these compounds and extracts. With coverage of both natural and synthetic cannabinoids, this broad coverage allows readers to learn about both adverse and non-adverse effects, including reactivity to pain, changes in behavior, and neuroactivity. This volume provides a platform for research on the effects of these compounds in brain function and neurological dysfunction. Extracts from the Cannabis sativa plant contain scores of psychoactive compounds in addition to the principal agent tetrahydrocannabinol... many of which are neuroactive.

  • Neurobiology and Physiology of the Endocannabinoid System

    • 1st Edition
    • Vinood B. Patel + 2 more
    • English
    Neurobiology and Physiology of the Endocannabinoid System offers readers a comprehensive reference on the neurobiology of this system and the use of cannabimimetic compounds to induce neurological changes and confer symptom relief. With sections on both natural and synthetic compounds, the book's broad coverage allows readers to learn about their use with multiple conditions, as well as the working biology of the endocannabinoid system, its receptors and its ligands. This volume provides a platform for research on the effects of this system and its modulation in brain function and neurological dysfunction.

  • Medicinal Usage of Cannabis and Cannabinoids

    • 1st Edition
    • Victor R. Preedy + 2 more
    • English
    There is a growing body of data supporting the usage of cannabis and cannabis-related products in alleviating or preventing symptoms in different diseases and conditions. Medicinal Usage of Cannabis and Cannabinoids offers readers a comprehensive reference on the medical usage and symptom relief provided by these compounds in a variety of disorders. With coverage of neurological diseases like Alzheimer’s and Parkinson’s, and a wide range of other afflictions including depression, anxiety, nausea, and cancer, this broad coverage allows readers to learn about symptom control but also physiological, psychological, and pharmacological effects of these compounds. Unique case reports are provided as well. This volume provides a platform for research on the use of these compounds in improving patient care, brain function, and neurological dysfunction.

  • Ozone Pollution and Plant Health: Understanding the Impacts and Solutions for Sustainable Agriculture

    • 1st Edition
    • Volume 108
    • English
    Advances in Botanical Research Volume 108: Ozone Pollution and Plant Health: Understanding the Impacts and Solutions for Sustainable Agriculture provides a comprehensive overview of the harmful effects of tropospheric ozone (O3) pollution on crop productivity, with a focus on how it is measured and modeled under climate change scenarios. The book discusses the sources of O3 pollution, including anthropogenic precursor gases, and how O3 exposure can impair photosynthesis, reduce gas exchange, induce early leaf senescence, and hamper growth in natural vegetation and crops. The book highlights how O3 interacts with plant physiology and metabolism, including through the activation of signal transduction pathways, changes in phytohormone signaling, and modulation of reactive oxygen species (ROS) generation and signaling. The book also explores the experimental and modeling methods used to assess the effects of O3 on crops, with a focus on studies conducted in Asia. The book emphasizes the importance of understanding the implications of ozone pollution for ensuring food security and protecting human and environmental health and suggests strategies such as using ozone-resistant cultivars of plants and crops. Additionally, the book discusses the broader context of air pollution and its impact on crop productivity, including the effects of other air pollutants on plants and crops and the need for mitigation strategies and policies to address agricultural losses. This book is essential reading for early-career researchers, sustainable agriculture practitioners, and policymakers interested in understanding the complex interactions between ozone pollution and plant productivity and finding solutions to mitigate the detrimental effects of ozone pollution on crops in a changing climate.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 114
    • Gregory S. Makowski
    • English
    Advances in Clinical Chemistry, Volume 114, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. New sections in the updated release include Growth differentiation factor 15 (GDF-15) in kidney diseases, Alkaptonuria - past, present and future, Alcohol Consumption and Nutritional Biomarkers in Early-Stage Alcohol-Associated Liver Disease, Advances in Liquid Biopsy–Based Markers in NSCLC, D-dimer testing: a narrative review, Evolving Markers in Amyotrophic Lateral Sclerosis, and more.

  • Opioids

    • 1st Edition
    • Volume 4
    • George F. Koob + 3 more
    • English
    A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Opioids, Volume 4 in the series, explores the molecular, cellular and systems in the brain responsible for opioid addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/antici...

  • Pancreatic Cancer: Basic Mechanisms and Therapies

    • 1st Edition
    • Volume 159
    • English
    Pancreatic Cancer: Basic Mechanisms and Therapies, Volume 159 in the Advances in Cancer Research, presents the latest release in this ongoing, well-regarded serial with invaluable information on the exciting and fast-moving field of cancer research. Pancreatic cancer (PC) is the third leading cause of cancer-related deaths in the United States. Greater than 90% PCs are Pancreatic ductal adenocarcinomas (PDAC) which have a dismal estimated 5-year overall survival of only 11%. PDAC is predicted to become the second leading cause of mortality in the United States by 2030. In the clinic, the PDAC patients often present with incurable disease at the time of first diagnosis. This cancer is particularly lethal because of its propensity to spread quickly to distant organs including the lymphatic system. PDAC metastasis occurs shortly after tumor initiation and is caused by a complex interaction between autonomous tumor cells and cellular elements of the tumor microenvironment. Although PDAC remains a challenging disease to treat and a leading cause of cancer-related deaths, progress is being made in disease etiology and pathogenesis, and intensive research is focused on developing optimal treatment approaches for patients. Considering the continuous progress being made in understanding PDAC pathogenesis and designing new therapies, it was considered timely to develop an up-to-date thematic issue of Advances in Cancer Research (ACR) focused on PDAC. In this thematic issue, we have included ten review articles by experts that cover cancer disparities, PDAC pathobiology, the roles of the tumor microenvironment, tumor heterogeneity, PC stem cells, genetic and signaling events critical for PDAC pathogenesis, Immunotherapy and chemoresistance in PDAC, and different PDAC mouse models. This special issue highlights recent research progress in PDAC, which bridges the gap between basic and clinical research.

  • Advances in Agronomy

    • 1st Edition
    • Volume 180
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 180, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field. Chapters in this new release include The Socio-Economic Impact of Fungicide Resistance in West Australia’s Wheatbelt, Microbial Inoculant Carriers: Soil Health Improvement and Moisture Retention in Sustainable Agriculture, Response Network of Plant-Soil-Rhizosphe... Environment to Drought Stress and their Regulatory Measures, and Agricultural Residues Management: Life Cycle Assessment Implications for Sustainable Agricultural Practices and Reduction of Greenhouse Gases Emissions, An Analysis of Earth Temperature and Related Series in Air and Soil.

  • Mitochondria and Bacterial Pathogens - Part B

    • 1st Edition
    • Volume 377
    • English
    Mitochondria and Bacterial Pathogens, Part B, Volume 375 discusses different pathogenic mechanisms that converge on the ability of bacteria to control the mitochondrial compartment of host cells. Chapters in this new release include Interaction between host cell mitochondria and Coxiella Burnetii, Control of mitochondrial functions by Pseudomonas aeruginosa in cystic fibrosis, Mitochondrial and bacterial ATP synthase: Structural similarities and divergences to exploit in the battle against M. tuberculosis, Role of mitochondria in the enteropathogenic Escherichia coli disease, Mitochondria dynamics and antibiotic resistance, and more.

  • Environmental Contaminants and Endocrine Health

    • 1st Edition
    • Oliana Carnevali + 1 more
    • English
    Environmental Contaminants and Endocrine Health focuses specifically on contaminants with hormonal disrupting activities. The book provides insights into the multiple effects of endocrine-disrupting chemicals (EDCs) and their mechanism of action (MoA) on metabolism, reproduction and the multiple physiological roles of the endocannabinoid system which has recently been indicated as new target. The content systematically covers EDC sources and effects, EDCs as sources of disease and health impairment in laboratory models, EDCs as the cause of disease and health impairment in humans and wild species, and the removal of hazardous pollutants from wastewaters to highlight intervention, mitigation and adaptation for reduced threat. This content will be a foundational resource for academic and research staff in endocrinology and hormone toxicology as well as for professors, researchers and students in these areas.

  • Accelerating Strategic Changes for Digital Transformation in the Healthcare Industry

    • 1st Edition
    • Patricia Ordonez de Pablos + 1 more
    • English
    Accelerating Strategic Changes for Digital Transformation in the Healthcare Industry discusses innovative conceptual frameworks, tools and solutions to tackle the challenges of mitigating major disruption caused by COVID-19 in the healthcare sector and society. It emphasizes global case studies and empirical studies, providing a comprehensive view of best lessons on digital tools to manage the health crisis. The book focuses on the role of advances in digital and collaborative technologies to offer rapid and effective tools for better health solutions for new and emerging health problems. Researchers, students, policymakers and members of the biomedical and medical fields will find this information invaluable. Specially, it pays attention to how information technologies help us in the current global health emergency and the coronavirus epidemic response, gaining more understanding of the new coronavirus and helping to contain the outbreak. In addition, it explores how these new tools and digital health solutions can support the economic and social recovery in the post-pandemic world.

  • Aptamers for Food Applications

    Safety, Authenticity, and Integrity
    • 1st Edition
    • Yiyang Dong
    • English
    Aptamers for Food Applications: Safety, Authenticity, and Integrity outlines the main applications of aptamers to ensure food safety, quality and compliance that are crucial for food science, public health and human sustainability. Aptamers or aptamer-based analytical devices are comprehensively summarized to tackle various food contamination or food adulteration problems. Topics covered in this book include aptamers for foodborne microbial pathogens, pesticide or veterinary drug residues, heavy metals, biotoxins, abused food additives, illegal food adulterants, POPs, GMOs, food allergens and food contact material migrants. It is therefore of interest for not only analytical investigators and food safety inspectors, but also regulatory practitioners and risk assessors in various food science and research fields.

  • Stem Cell Laboratory Techniques

    A Guide for Researchers and Students
    • 1st Edition
    • Suresh Kumar Kailasa + 2 more
    • English
    Stem Cell Laboratory Techniques: A Guide for Researchers and Students introduces the reader to stem cell culture, handling techniques and versatile applications used by researchers. Sections introduce stem cells, including definitions, types and basic use of stem cells in biomedical science research. The book explains laboratory procedures and techniques ranging from the extraction of stem cells from animals, cell seeding and culture, harvest and maintenance of stem cells, stem cell characterization, accurate recording, quality control, and more. In addition, it guides researchers on topics such as transcriptome analysis, proliferation study analysis, and microphysiological study. Final sections cover useful and recent applications in stem cells, such as gene editing techniques and the preparation of stem cells for in vitro study, as well as stem cell lab design and equipment used in the lab. Lastly, human and animal research ethics are discussed.

  • The Role of Gasotransmitters In the Amelioration of Arsenic Toxicity in Plants

    Biology and Biotechnology
    • 1st Edition
    • Bruno Lemos Batista + 2 more
    • English
    The Role of Gasotransmitters In the Amelioration of Arsenic Toxicity in Plants: Biology and Biotechnology, in the Plant Gasotransmitter series, provides research on how gasotransmitters can reduce the stress faced by plants through arsenic contamination. With a strong focus on metabolic processes, the book presents the various pathways and mechanisms associated with gasotransmitters as part of arsenic amelioration. Initial chapters discuss the effects of arsenic on the plant genome and metabolome, as well as the mechanisms behind the uptake and translocation of arsenic in plants. The book then takes a deep dive into the role of gasotransmitters, highlighting plant physiological responses. This is an essential resource for students, researchers and agronomists interested in plant physiology, biochemistry and plant hormones.

  • New Experimental Probes for Enzyme Specificity and Mechanism

    • 1st Edition
    • Volume 685
    • English
    New Experimental Probes for Enzyme Specificity and Mechanism, Volume 685, the latest release in the Methods of Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics including Subverting Hedgehog Protein Autoprocessing by Chemical Induction of Paracatalysis, New Mechanistic Probes to Identify Novel Substrates for N-Myristoyltransfera... Phosphonate and α Fluorophosphonate Analogues of D Glucose 6 Phosphate as Active-Site Probes of 1L-Myo-Inositol 1 phosphate Synthase, Kinetic Mechanism of Nicotine-Degrading Enzyme Probed by Stopped-Flow Kinetic Analyses, Kinetics and Mechanism for Enzyme-Catalyzed Reactions of Substrate Pieces, and more. Additional chapters cover Kinetics and Mechanism for Reactions of Enzyme Pieces, Evaluation of allostery for the bienzyme assembly of a 3-deoxy-D-arabino heptulosonate-7-phos... synthase and chorismate mutase, Recognition and Catalysis of Reactions of Chiral Substrates by Mandelate Racemase, Innovative and emerging modalities of EGFR kinase inhibitors, Characterization of the Aminoacrylate Intermediate of Tyrosine Phenol-Lyases, and much more.

  • Microbial Inoculants

    Recent Progress and Applications
    • 1st Edition
    • Vijay Kumar Sharma + 4 more
    • English
    In the recent past, beneficial microorganisms have been sustainably used in agriculture as a safe, economic, and effective alternative to chemical fertilizers or pesticides. These beneficial microbes, including bacteria, actinomycetes, and yeast, were efficiently applied in soil, seeds, fruits, or plants as inoculants, to achieve the optimum agricultural yield.An efficient delivery method or enhanced shelf life of microbial inoculants in the soil or seed is still a matter of concern. The response of local genetic or ecological factors, after microbial applications, are also unknown and less studied. Therefore, Microbial Inoculants: Recent Progress and Applications fulfills the need to explore and learn about an efficient delivery mechanism, selection of microbial strain as inoculants, and related technological advances, for the efficient and productive use of microbial inoculants. Moreover, factors like methods of formulation, interaction between host plant and microbe, impact of inoculation on the metabolomics of plants, the effect of microbial inoculants on soil dynamics, proteomics approach of plant-microbe interaction, as well as the registration and regulation process of bio inoculants for commercial production are described in 16 chapters by the leading academicians and researchers from different parts of the world.

  • Global Perspectives on the Transmission of Zoonotic RNA Viruses from Wild Animal Species to Humans

    Zoonotic, Epizootic, and Anthropogenic Viral Pathogens
    • 1st Edition
    • Jayashree Seema Nandi
    • English
    Global Perspectives of the Transmission of Zoonotic RNA Viruses from Wild Animal Species to Humans: Zoonotic, Epizootic, and Anthropogenic Transmission Viral Pathogens elaborates on the current knowledge surrounding the transmission of zoonotic RNA viruses from different wild animal species to humans, including updates on the reverse transmission of pathogens to humans across the globe, with coverage of rodents, pigs, birds and primates. This reference goes beyond the phenomena occurring in African and American regions to provide further study of zoonotic pathogens from the entire world, including various parts of Asia such as India. The book comprehensively covers new knowledge on many diverse wild primate species for a global perspective on the phenomena of cross-species transmissions of pathogenic RNA viruses. Against the backdrop of the current global Covid-19 pandemic, this reference helps solve the problem of incomplete knowledge on global epidemiology of zoonotic RNA viruses. RNA viruses have pandemic, epidemic and epizootic potentials caused by Influenza viruses, Avian Influenza viruses, and other infectious viruses.

  • Advances in Accelerators and Medical Physics

    • 1st Edition
    • Toshiyuki Shirai + 2 more
    • English
    Radiotherapy is now one of the major cancer treatments. The field of accelerator and medical physics is important and growing to support high precision cancer radiotherapy. Advances in Accelerators and Medical Physics provides in-depth and comprehensive coverage of the basic concepts in x-ray therapy, electron beam therapy, particle therapy, boron neutron capture therapy, and molecular imaging and therapy. Novel technologies such as FLASH therapy and laser ion accelerator are also introduced. Each section of the book presents the current state of accelerators, irradiation methods and therapy technologies, as well as future trends in advanced research. This book will serve as a key resource for researchers and students to find all information on latest cancer radiotherapy technologies and methods.

  • Alternative Methods in Neurotoxicology

    • 1st Edition
    • Volume 9
    • English
    Alternative Methods in Neurotoxicology, Volume Nine, the latest release in this series, provides an overview of important in vitro and non-vertebrate animal models available to study the neurotoxicity of a range of toxicants of occupational and environmental relevance. Chapters in this new release include Evaluation of mitochondrial function in neurotoxicology using alternative models, Planarians as a model to study neurotoxic agents, Role of Drosophila melanogaster in neurotoxicology studies: Responses to different harmful substances, Neurotoxicology of metals and metallic nanoparticles in Caenorhabditis elegans, Neurotoxicology of environmental toxicants using Caenorhabditis elegans as a model, Nauphoeta cinerea as an emerging model in neurotoxicology, and more. Other chapters cover Human Neural Stem Cells in Developmental Neurotoxicology: Current Scenario and Future Prospects, Use of Drosophila melanogaster for advances in developmental neurotoxicology studies, 3D neurospheres and neurotoxicity of organophosphorus and TCE, Genetic factors in methylmercury-induce... neurotoxicity: what we have learned from Caenorhabditis elegans models, and more.

  • Hygienic Design of Food Factories

    • 2nd Edition
    • John Holah + 2 more
    • English
    Advances in food safety knowledge, combined with the continuing rapid development of new food products, have had an impact on the need for improved hygiene in the food manufacturing infrastructure. This has created a need for the second edition of Hygienic Design of Food Factories, which expands all existing chapters and includes new topics, such as cold storage and the control of air in food refrigeration facilities. Additionally, chapters explore the prevention of food contamination when building during production, the risk assessment of which is becoming important globally, and hygienic building design regulations in Russia and Brazil. Divided into 6 parts, the book is now thoroughly updated and expanded. Part one reviews the implications of hygiene and construction regulation in various countries on food factory design, while taking into account retailer requirements as well. Part two describes site selection, factory layout and the associated issue of airflow. Parts three through four and five then address the hygienic design of the essential parts of a food factory. These include walls, ceilings, floors, selected utility and process support systems, entry and exit points, storage areas and changing rooms. Lastly part six covers the management of building work and factory inspection when commissioning the plant. With its distinguished editors and international team of contributors, Hygienic Design of Food Factories, 2nd edition, continues to be an essential reference for managers of food factories, food plant engineers and all those with an academic research interest in the field.

  • Effective Use of Social Media in Public Health

    • 1st Edition
    • Kavita Batra + 1 more
    • English
    Effective use of Social Media in Public Health offers a well-organized and comprehensive review of social media and its impact on people’s lives and the public health sector. Divided into sections, the book addresses the growing use (and importance) of social media in conducting and disseminating research findings and covers an array of issues from cyberbullying to diversity and inclusion. Written by health educators and practitioners for health educators and practitioners, this book is a timely resource on the topics discussed.

  • Advances in Marine Biology

    • 1st Edition
    • Volume 94
    • Jean-Francois Hamel
    • English
    Advances in Marine Biology, Volume 94, the latest release in this series that highlights new advances in the field, presents interesting content written by an international board of authors. Chapters in this new release include The Falkland Islands marine ecosystem: a review of the seasonal dynamics and trophic interactions across the food web, An impact of non-native species invasions on the Caspian Sea biota, A global synthesis of microplastic contamination in wild fish species: challenges for conservation, implications for sustainability of wild fish stocks and future directions, and Addressing Underwater Noise: Joint Efforts and Progress on Its Global Governance.

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