Advanced Drug Delivery Systems for Colonic Disorders
- 1st Edition - November 7, 2023
- Latest edition
- Editors: Harish Dureja, Raimar Loebenberg, Sachin Kumar Singh, Muralikrishnan Dhanasekaran, Kamal Dua
- Language: English
Advanced Drug Delivery Systems for Colonic Disorders presents state-of-the-art methods for targeted drug delivery to the colon. These methods can prolong drug half-lives, improve b… Read more
Advanced Drug Delivery Systems for Colonic Disorders presents state-of-the-art methods for targeted drug delivery to the colon. These methods can prolong drug half-lives, improve bioavailability, optimize pharmacokinetics, and reduce medication dosing frequency. Chapters allow readers to not only become familiar with advancements, but also understand concepts by providing illustrations, figures, and informative tables. Contents cover an overview of colonic diseases, the cellular and molecular mechanisms involved, current and traditional therapeutic approaches, biomaterials, oral drug delivery methods, targeted drug delivery, nutraceuticals and herbal medicine approaches, prebiotics, probiotics and symbiotics, nanomedicine approaches, and the status of clinical trials.
This book is the perfect resources for researchers in pharma, biomaterials, and nutrition to help familiarize them with new and upcoming therapeutic methods. Research physicians in GI can also benefit from reading this book for its clinical applications.
- Covers recent perspectives and challenges towards the treatment of colonic disorders
- Provides insights into how advanced drug delivery systems can be effectively used for the management of various types of colonic disorders
- Discusses drug delivery strategies to manage inflammatory bowel disease (chronic inflammation in the digestive tract), ulcerative colitis (inflammation and ulcers in colon), Crohn's disease, Colonic polyps, Shigellosis, Colon Bleeding or Hemorrhage, Diverticulosis and colon cancer
Researchers in academic and industry working in the field of colonic disorders and drug delivery. Researchers in the related fields of Nanobiotechnology, Molecular Biology; Medical Doctors in colonic disorders
1. Introduction to colonic disorders
Manvi Singh, Puru Goel, Mayank Phagna, Reena Badhwar, Zeenat Iqbal and Mohd. Aamir Mirza
2. Cellular and molecular mechanisms involved in colonic disorders
Simranjit Kaur, Arshdeep Singh, Harpreet Kaur, Jagbir Singh and Rajbir Bhatti
3. Current approaches for treatment of colonic disorder
Manish Gupta, Priya Sen, Mahendra Saini, Mahaveer Singh, Pawan Bagiyal, Pramod Kumar and
Gaurav Gupta
4. Polysaccharides based drug delivery systems for the treatment of colon diseases
Sadaf Arfi, Nimisha Srivastava and Deepti Dwivedi
5. Synthetic polymers as biomaterials for the treatment of colon diseases
Sundeep Chaurasia and Brahmeshwar Mishra
6. Mucoadhesive polymers as biomaterials for the treatment of colon disorders
Nitesh Kumar, Priyanka Verma, Varun Kumar, Rachel Kaul and Surbhi Mishra
7. Colon-responsive oral drug delivery for combating colonic disorders
Anindita Behera
8. Colon-responsive targeted drug delivery for treating colonic disorder
Anil K. Philip, Bassim I. Mohammad and Hayder A. Al-Aubaidy
9. Advancement in targeted drug delivery systems in managing colonic disorders
C. Sarath Chandran, Krishnameera Sajayan, Jeeva C. Soman, P.K. Anjana, K.K. Swathy, A.S. Vishnu and Shijina Kappally
10. Nutraceuticals and phytoceuticals in the treatment of colonic disorders
Nitin Verma, Jatin Kumar, Neha Kanojia, Komal Thapa and Kamal Dua
11. Role of Prebiotics, Probiotics and synbiotics in the management of colonic disorders
Faizan Naeem Razali, Wuen Yew Teoh, Muhammad Zaki Ramli, Ching-Yee Loo and Charles Gnanaraj
12. Era of biotics in managing colonic disorders
Shvetank Bhatt, K. Anitha, Sujit Kumar Sah, Nishant Prasad Apte, Sakina. Mullamitha and
Jamila Chechatwala
13. Innovations in liposomal drug delivery: paving the way for personalized cancer therapy
Alaa A.A. Aljabali, Mohammad A. Obeid, Mohamed El-Tanani and Murtaza M. Tambuwala
14. Nanoparticulate drug delivery systems for colonic disorders
Girish Kumar, Tarun Virmani, Ashwani Sharma, Reshu Virmani and Kamla Pathak
15. 3D printing-assisted colon-targeted drug delivery systems
Chandrakantsing Pardeshi, Ganesh Shevalkar, Mahesh Umbarkar, Dipak Bari, Kamalesh Mali,
Sameer Lakade and Monica Garcıa
16. Radiopharmaceutical-based approaches for the determination of colon-targeting
efficiency
Akshita Arora, Anshul Sharma, Richa Kumari and Nitin Sharma
17. Colonic disorder management: challenges an prospects
Alan Raj, M. Sonal Sekhar and Angel Treasa Alex
18. Clinical trials and regulatory aspects of drug delivery system for colonic disorders
Riya Shivgotra, Manjot Kaur, Shubham Thakur, Bindu Soni, Hossamaldeen Bakrey and Subheet Kumar Jain
- Edition: 1
- Latest edition
- Published: November 7, 2023
- Language: English
HD
Harish Dureja
Dr. Harish Dureja is Professor and Head, Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak. Dr. Dureja is also the Director, Centre for IPR Studies and Director, Professional Consultancy Cell. Dr. Dureja has more than 22 years of teaching experience. He also holds 18 years research experience in the field of nanoparticulate drug delivery, regulatory affairs and in silico ADME modeling. Dr. Dureja has been awarded with Gold-Medal for the best Ph.D. thesis and research projects worth 1.2 Crore from various funding agencies. He has filed an Indian patent and written a book and authored more than twenty five book chapters. He has published 265 publications in various international and national journals of repute. He worked as Chairman-Scientific Services Committee (LOC) during 69th IPC at Chitkara University, Raj-pura. He also worked as content writer for e-Pathashala program of Ministry of Human Resources Development for Post Graduate course of Pharmaceutical Sciences for the paper novel drug delivery system. He has delivered more than 180 invited Lectures in various conferences, seminars and symposiums and has guided 60 PG scholars and 10 students for doctoral work. He has been awarded the Gold-Medal for Best Ph.D. Thesis, Best Paper Award - Prof. M.L. Khorana Memorial Prize Award – 2005 and Dr. R.L. Nicore award - 2018. He has published six special issues as a Guest Editor for the Journals published by Bentham Science Publishers, and one issue published by Frontiers, Switzerland. He is currently also serving as President, Association of Pharmaceutical Teachers of India (APTI), Haryana State Branch.
Affiliations and expertise
Professor, Department of Pharmaceutical Sciences, Maharshi Dayanand University, IndiaRL
Raimar Loebenberg
Dr. Raimar Löbenberg holds a BSc in pharmacy from the Johannes Gutenberg-University in Mainz, Germany and PhD in pharmaceutics from the Johann Wolfgang Goethe-University in Frankfurt. He joined the University of Alberta in 2000. His research interests are in Biopharmaceutics to predict the oral performance of drugs and botanicals and inhalable nanoparticles to treat lung diseases like cancer or tuberculosis. He is founder and director of the Drug Development and Innovation Centre at the University of Alberta. He was president of the Canadian Society for Pharmaceutical Sciences 2014 & 2015. He is member of the United States Pharmacopeia Dietary Supplement Expert Committee. He is Vice Chair of the Specialty Committee of Traditional Chinese Medicine in Pharmaceutics of the World Foundation of Chinese Medicine Science. He is member of the Health Canada Scientific Advisory Committee on Pharmaceutical Sciences and Clinical Pharmacology.
Affiliations and expertise
Professor, Faculty of Pharmacy & Pharmaceutical Sciences, University of Alberta, CanadaSS
Sachin Kumar Singh
Dr. Sachin Kumar Singh, is working as professor and head of Pharmaceutical Chemistry and Quality Assurance at School of Pharmaceutical Sciences, Lovely Professional University, India. He is an honorary professor at Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), School of Public Health, University of Technology Sydney, Australia and School of Medical and Life Sciences, Sunway University, 47500 Sunway City, Malaysia. He has 14 years of teaching and research experience. Dr. Singh has completed one DST-SERB funded project on development of SNEDDS of Polypeptide-k for treatment of diabetes mellitus. He has published 500 plus research papers with cumulative impact of 1500 plus, authored 5 books and 25 book chapters. He has 10 granted patents to his credit. He is expert in development of novel drug delivery systems, synbiotics based formulations, analytical and bioanalytical method development and BA-BE studies. He has graduated 17 PhD students and 35 M Pharmacy students and currently graduating 3 masters and 6 PhD students. He is also featured under top 2% scientists of world as per the list of 2021, 2022 and 2023, published by Stanford University, USA. Currently his “h” index is 48 with 11000 plus citations. He is a recipient various national awards including Dr. B.C. Deb memorial award for popularization of science-2020 (honoured by Indian Science Congress Association), Bharat Shiksha Ratan Award-2014 (by Global Society for Health and Educational Growth, Delhi, India) and Bharat Gaurav Puraskar-2022 (by KTK outstanding achievers and education foundation, New Delhi) and Distinguished Alumnus Award (by Sree Siddaganga College of Pharmacy, Tumakuru, Karnataka).
Affiliations and expertise
Professor and head of Pharmaceutical Chemistry and Pharmaceutical Analysis, School of Pharmaceutical Sciences, Lovely Professional University, IndiaMD
Muralikrishnan Dhanasekaran
Muralikrishnan Dhanasekaran, is a Professor of Pharmacology and Toxicology at the Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University. He earned his Ph.D. in 1999 from the Jadavpur University, India, in neuropharmacology. From 1999-2001, he became a post-doctoral fellow at the University of Nebraska Medical Center, Omaha, Nebraska, and the Uni-versity of North Dakota School of Medicine and Health Sciences, Grand Forks, ND. He served as a re-search instructor of pharmacology at Texas A & M Health Sciences, Temple, TX. His major area of teaching and research is related to pathophysiology, pharmacology, and toxicology in dementia, movement disorders, addiction (substances of abuse-designer drugs, nicotine, alcohol), hyperglycemia, epilepsy, and aging. His research was funded by the Alzheimer’s Association and Pharmaceutical com-panies in the USA. He has over one hundred and thirteen peer-reviewed publications, fifty book chap-ters, and around four hundred abstracts in national and international meetings in the area of pharma-cology, toxicology, and natural bioactives. He has received several awards for teaching, service, and outreach. He has been an editor or on the editorial board for several books and journals including nat-ural products, pharmacology, toxicology, and neuropharmacology.
Affiliations and expertise
Professor of Pharmacology and Toxicology ,Department of Drug Discovery and Development,Harrison College of Pharmacy, Auburn University, Auburn, USAKD
Kamal Dua
Dr. Kamal Dua is a renowned researcher in pharmaceutics and drug delivery, with dual doctorates in Pharmaceutical Sciences and Immunology & Microbiology. As an Associate Professor at the University of Technology Sydney, he specializes in managing chronic inflammatory diseases, focusing on nanocarrier-based therapies. He also serves as an Adjunct Assistant Professor at the University of Alberta and holds multiple international adjunct positions. With over 190 peer-reviewed publications and more than 16,000 citations, Dr. Dua is recognized as a leading figure in toxicology and pharmaceutical sciences in Australia. His innovative teaching combines traditional and modern methods, fostering a dynamic learning environment. A recipient of numerous accolades, including being named one of Australia's Top 250 researchers in 2024, he is committed to mentoring emerging scientists and advancing novel therapeutic solutions that aim to transform clinical practices and improve patient outcomes worldwide.
Affiliations and expertise
Senior Lecturer, Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, NSW, AustraliaRead Advanced Drug Delivery Systems for Colonic Disorders on ScienceDirect