
Advances in Clinical Chemistry
- 1st Edition, Volume 117 - November 9, 2023
- Imprint: Academic Press
- Editor: Gregory S. Makowski
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 9 2 9 4 - 4
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 9 2 9 5 - 1
Advances in Clinical Chemistry, Volume 117, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scient… Read more

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Request a sales quote- Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science
- Authored by world-renowned clinical laboratory scientists, physicians and research scientists
- Presents the international benchmark for novel analytical approaches in the clinical laboratory
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter One: Viscoelastic Testing Methods
- Abstract
- 1 Introduction
- 2 Physiology of hemostasis in VET
- 3 History
- 4 Current methods
- 5 Interpretation of VET results
- 6 Clinical applications
- 7 Practice settings
- 8 Conclusion
- Acknowledgments
- References
- Chapter Two: The role of sRAGE in cardiovascular diseases
- Abstract
- 1 Introduction
- 2 Atherosclerosis
- 3 Coronary artery disease
- 4 Heart failure
- 5 Conclusions
- References
- Chapter Three: Advances in preeclampsia testing
- Abstract
- 1 Introduction & clinical definitions
- 2 Characteristics of preeclampsia
- 3 Clinical guideline recommendations and laboratory testing for preeclampsia screening
- 4 Analytical and clinical perspectives on PlGF and sFlt-1 testing
- 5 Future research directions
- 6 Summary
- Acknowledgment
- References
- Chapter Four: Immunohematological testing and transfusion management of the prenatal patient
- Abstract
- 1 Introduction
- 2 Red cell antigens and antibodies
- 3 Maternal red cell alloimmunization
- 4 Hemolytic disease of the fetus and newborn
- 5 Routine immunohematological testing of the prenatal patient
- 6 Testing for prenatal patients with significant red cell antibodies
- 7 Preparing RBC units for fetal transfusions
- 8 Immunohematological testing of the newborn [-]
- 9 Pregnancy arising from assisted reproductive technology
- 10 Unresolved questions in prenatal immunohematology
- 11 Case studies
- 12 Future prospects
- References
- Chapter Five: Lead poisoning: Clinical and laboratory considerations
- Abstract
- Abbreviations
- 1 Introduction and historical background
- 2 Clinical effects of lead exposure
- 3 Lead screening
- 4 Methods for the detection of lead in the body
- 5 Summary
- References
- Chapter Six: Advances in clinical chemistry patient-based real-time quality control (PBRTQC)
- Abstract
- 1 Introduction
- 2 Quality control
- 3 Patient-based real-time quality control
- 4 PBRTQC techniques
- 5 Exponentially adjusted weighted moving mean (EAMM), trend (T)EAMM, and Bull’s algorithm
- 6 Statistical procedures and performance metrics
- 7 PBRTQC on multiple analyzers
- 8 Optimization techniques
- 9 Information technology and software
- 10 Monitoring PBRTQC by technologists in a live environment
- 11 Validation and verification
- 12 Integration with practice and examples
- 13 Advantages and disadvantages
- 14 The future
- 15 Conclusion
- References
- Index
- Edition: 1
- Volume: 117
- Published: November 9, 2023
- No. of pages (Hardback): 286
- No. of pages (eBook): 232
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780443192944
- eBook ISBN: 9780443192951
GM
Gregory S. Makowski
Dr Gregory S Makowski is a board-certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President Clinical Laboratory Services Hartford HealthCare in Connecticut.