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Elsevier

Books in Life sciences

  • MicroRNA in Regenerative Medicine

    • 1st Edition
    • Chandan K. Sen
    • English
    This work encapsulates the uses of miRNA across stem cells, developmental biology, tissue injury and tissue regeneration. In particular contributors provide focused coverage of methodologies, intervention and tissue engineering. Regulating virtually all biological processes, the genome’s 1048 encoded microRNAs appear to hold considerable promise for the potential repair and regeneration of tissues and organs in future therapies. In this work, 50 experts address key topics of this fast-emerging field. Concisely summarizing and evaluating key findings emerging from fundamental research into translational application, they point to the current and future significance of clinical research in the miRNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of miRNA across repair and regeneration, and special coverage of methodologies and interventions as they point towards organ and tissue engineering

  • Protides of the BIological Fluids

    Proceedings of the Thirtieth Colloquium, 1982
    • 1st Edition
    • Volume 30
    • H. Peeters
    • English
    Protides of the Biological Fluids: Proceedings of the 30th Colloquium, 1982 is a collection of manuscripts presented at the 30th Colloquium, held in Brussels, Belgium in 1982. This text is organized into three sections encompassing 160 chapters. The first section highlights the mechanisms of the normal and abnormal mental function through evaluation of neuroproteins or the so-called “think-proteins”. This section describes the manifestations, clinical features, diagnosis, and therapeutic options of nervous system diseases. The second section tackles monoclonal proteins as a reagent to detect antigens. This section deals with the significant progress in cancer therapy and the binding of cytotoxic drugs to monoclonal antibodies. The third section considers the potential of isodalt electrophoresis and high-pressure liquid chromatography, with particular emphasis on their application to protein analysis in biological fluids. This book will be of great value to biochemists, clinical chemists, and clinicians.

  • Advances in Lipid Research

    • 1st Edition
    • Volume 6
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 6 provides information pertinent to brain cholesterol and myelin lipids. This book reviews the various aspects of the physiology, chemistry, and biochemistry of lipids. Organized into seven chapters, this volume begins with an overview of the separation of lipoproteins and discusses lipid metabolism in microorganisms. This text then provides a discussion of lipid metabolism in mycoplasmas. Other chapters consider the various aspects of metabolism of the lipid quinones and explore the relationship between lipids and atherosclerosis as a continuing source of biochemical, medical, and nutritional interest. This book discusses as well a comparative aspect of the development of atherosclerosis and explains the chemistry of bile acids. The final chapter deals with the aspects of steroid separations as well as with regard to separation of other metabolites that may influence lipid metabolism. This book is a valuable resource for biologists, biochemists, scientists, and research workers.

  • Neurobiology of Brain Disorders

    Biological Basis of Neurological and Psychiatric Disorders
    • 1st Edition
    • Michael J. Zigmond + 2 more
    • English
    Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases.

  • Neuromuscular Disorders of Infancy, Childhood, and Adolescence

    A Clinician's Approach
    • 2nd Edition
    • Basil T. Darras + 3 more
    • English
    Neuromuscular disorders are diagnosed across the lifespan and create many challenges especially with infants, children and adolescents. This new edition of the definitive reference, edited by the established world renowned authorities on the science, diagnosis and treatment of neuromuscular disorders in childhood is a timely and needed resource for all clinicians and researchers studying neuromuscular disorders, especially in childhood. The Second Edition is completely revised to remain current with advances in the field and to insure this remains the standard reference for clinical neurologists and clinical research neurologists. The Second Edition retains comprehensive coverage while shortening the total chapter count to be an even more manageable and effective reference.

  • Current Topics in Bioenergetics

    Volume 3
    • 1st Edition
    • D. Rao Sanadi
    • English
    Current Topics in Bioenergetics, Volume 3 provides information pertinent to the phenomena associated with biological energy transduction at different levels of sophistication. This book discusses the energy-linked processes in mitochondria. Organized into seven chapters, this volume begins with an overview of the core of the mechanism of oxidative phosphorylation. This text then explains the basic features of artificial membranes model system and its usefulness in probing membrane phenomena. Other chapters consider the thermodynamic and kinetic aspects of active transport of ions and attempt to relate photoreception with the subsequent electrophysiological events. This book discusses as well the regulation of respiration by muscular activity and on energy transduction in phototropism and phototaxis. The final chapter deals with the mechanism of phototaxis in microorganisms and explains the phenomenon as a translational response of a freely moving organism to a light stimulus. This book is a valuable resource for biochemists, cell biologists, and physiologists.

  • Advances in Lipid Research

    • 1st Edition
    • Volume 4
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 4 provides information pertinent to the actions of catecholamines to lipid metabolism. This book discusses lipid metabolism in microorganisms wherein one relates specifically to the fatty acids of microorganisms and the other to general aspects of lipid metabolism in microorganisms. Organized into seven chapters, this volume begins with an overview of some of the contributions of lipid research to the understanding of the clotting mechanism. This text then examines the extent to which dietary carbohydrate interferes in lipid metabolism. Other chapters consider the lipid-mobilizing effects of adrenomimetic agents, which are highly specific for the depot type of adipose tissue. This book discusses as well a number of areas of bacterial lipid biochemistry that are under investigation. The final chapter deals with the procedures for assessing the purity of labeled lipids by organic synthesis, biosynthesis, and isotope exchange techniques. This book is a valuable resource for biochemists, scientists, and research workers.

  • Advances in Lipid Research

    • 1st Edition
    • Volume 2
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 2 provides a discussion of theories of triglyceride structure and presents a provocative comparison of in vitro versus in vivo lipid biosynthesis. This book covers brain phosphoinositide research, synthesis of phosphoglycerides, and the chemistry of lapoamino acids and phosphatidylglycerol... Organized into eight chapters, this volume begins with an overview of the procedure for calculating the percentages of the individual triglycerides as well as for triglyceride families. This text then examines the complex field of bacterial lipids. Other chapters consider the two aspects of the relationship between lipid metabolism and atherosclerosis. This book discusses as well the lipolytic and esterolytic activity of various tissues in connection with lipid transport and its relevancy to the development of atherosclerosis. The final chapter deals with the methods best adopted for in vitro and in vivo investigations of lipid biosynthesis. This book is a valuable resource for phospholipid chemists, biochemists, and scientists.

  • Advances in Lipid Research

    • 1st Edition
    • Volume 5
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 5 presents information pertinent to the chemistry, biochemistry, and physiology of lipids. This book discusses the metabolism of myelin lipids and explains the factors affecting brain cholesterol. Organized into nine chapters, this volume begins with an overview of the biosynthesis of fatty acids. This text then discusses the physiology of adipose tissue in which aspects of adipose tissue physiology of a number of animal species are compared. Other chapters consider the physiological, biochemical, and morphological changes observed in ethionine-induced fatty liver. This book discusses as well the metabolism of lipids by macrophages and the relationship of this phenomenon to atherosclerosis. The final chapter deals with the phase diagrams of glyceride mixtures, a subject that is more physicochemical in nature and suggests another area of investigation to biologists. This book is a valuable resource for biologists, biochemists, neurochemists, scientists, and research workers.

  • Advances in Lipid Research

    • 1st Edition
    • Volume 3
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 3 presents the analysis of human serum lipoproteins and emphasizes the possibilities inherent in the application of computer methods to such analyses. This book discusses the effects of various drugs on the other important component of the serum lipids, the phospholipids. Organized into six chapters, this volume begins with an overview of the possibility of a dehydrogenation toward the methyl group. This text then presents a detailed discussion of lipoprotein structure, metabolism, and catabolism. Other chapters consider some potentially significant revisions in lipoprotein procedure, including additions to the technology of lipoprotein analysis. This book discusses as well the chemistry and metabolism of plasma lipoprotein as related to physiological and disease states. The final chapter deals with the advances in methods of purification and studies of the properties and mode of action of lipases. This book is a valuable resource for organic chemists, neurochemists, and biochemists.

  • Current Topics in Bioenergetics

    Volume 2
    • 1st Edition
    • D. R. Sanadi
    • English
    Current Topics in Bioenergetics, Volume 2 provides information pertinent to biological energy transduction, both at the molecular level and in systems having a higher degree of organization. This book presents the contractile mechanisms in cilia and flagella. Organized into 10 chapters, this volume begins with an overview of the concept of the photosynthetic unit that has been deeply involved in all models of photosynthesis. This text then discusses the mechanisms of light-induced conformational changes in chloroplasts, mediated by ion transport. Other chapters consider the conservation and utilization of energy derived from the oxidation of organic substrates by plant mitochondria. This book discusses as well the role of ubiquinone, which has undergone the familiar difficulty in establishing whether a redox active component is an obligatory member of the electron transfer in the respiratory chain. The final chapter deals with the steady state potentials found in the inner ear of mammals. This book is a valuable resource for otolaryngologists and scientists.

  • Current Topics in Bioenergetics

    Volume 1
    • 1st Edition
    • D. R. Sanadi
    • English
    Current Topics in Bioenergetics, Volume I presents the molecular basis of biological energy transduction. This book focuses on photosynthetic reactions. Organized into seven chapters, this volume begins with an overview of the second photosystem that evolves oxygen from water. This text then presents a brief historical background of fluorescence in relation to the development of the two-pigment-system concept of photosynthesis and indicates the significance of fluorescence measurements in the study of photosynthesis. Other chapters consider mitochondrial ion transport, its relation to active transport in cells, and its possible effects on muscle contraction. This book discusses as well the concept of uncoupling in oxidative phosphorylation. The reader is also introduced to the biochemical basis of luminescence, which has been investigated in several organisms. The final chapter deals with the study of mitochondrial cations and of the cation transport. This book is a valuable resource for biochemists, molecular biologists, scientists, and research workers.

  • New Approaches to Prokaryotic Systematics

    • 1st Edition
    • Volume 41
    • Michael Goodfellow + 2 more
    • English
    Volume 41 of Methods in Microbiology is a methods book designed to highlight procedures that will revitalize the purposes and practices of prokaryotic systematics.This volume will notably show that genomics and computational biology are pivotal to the new direction of travel and will emphasise that new developments need to be built upon historical good practices, notably the continued use of the nomenclatural type concept and the requirement to deposit type strains in at least two service culture collections in different countries.

  • Class 1 Devices

    Case Studies in Medical Devices Design
    • 1st Edition
    • Peter J. Ogrodnik
    • English
    The Case Studies in Medical Devices Design series consists of practical, applied case studies relating to medical device design in industry. These titles complement Ogrodnik’s Medical Device Design and will assist engineers with applying the theory in practice. The case studies presented directly relate to Class I, Class IIa, Class IIb and Class III medical devices. Designers and companies who wish to extend their knowledge in a specific discipline related to their respective class of operation will find any or all of these titles a great addition to their library. Class 1 Devices is a companion text to Medical Devices Design: Innovation from Concept to Market. The intention of this book, and its sister books in the series, is to support the concepts presented in Medical Devices Design through case studies. In the context of this book the case studies consider Class I (EU) and 510(k) exempt (FDA) . This book covers classifications, the conceptual and embodiment phase, plus design from idea to PDS.

  • Glucose Intake and Utilization in Pre-Diabetes and Diabetes

    Implications for Cardiovascular Disease
    • 1st Edition
    • Ronald Ross Watson + 1 more
    • English
    This important reference, edited by Ronald Ross Watson and Betsy Dokken, collects the research needed to make the distinct connection between pre-diabetes, diabetes, and cardiovascular disease. Glucose Intake and Utilization in Pre-Diabetes and Diabetes: Implications for Cardiovascular Disease explains the mechanisms of progression from pre-diabetes to diabetes to cardiovascular disease. Since pre-diabetes and diabetes are important cardiovascular disease risk factors, and impaired glucose metabolism among cardiac patients is extremely prevalent, the importance of reviewing pre-diabetes and its involvement in CVD complications is vital as one applies food and glycemic control to slow progress to diabetes and heart disease. The book further focuses on glucose intake and utilization in diabetes, including coverage of diabetes in the development and pathology of cardiovascular disease, risks and epidemiology of cardiovascular problems promoted by diabetes, macrovascular effects and their safety in therapy of diabetics, beta cell biology and therapy of diabetes, and nutrition to modulate diabetes.

  • The Science of Fitness

    Power, Performance, and Endurance
    • 1st Edition
    • Greg LeMond + 1 more
    • English
    The Science of Fitness: Power, Performance, and Endurance clearly explains the vital connection between diet and exercise in the human body. With this knowledge, you can use the right exercise and nutrition to obtain a higher quality life, prevent disease, and slow the aging process. Authored in a straightforward style and with color images throughout, this book explores the cellular science behind fitness, protein synthesis, and healthy living. With it you will learn the most recent and important discoveries in the relationships between physical fitness, nutrition, weight loss, and weight management. It provides key information on the body’s mitochondrial processes and their role in aging, along with well-informed discussions on general nutrition, sports nutrition, exercise physiology, how to enhance athletic performance, and how exercise strengthens the mind. Whether you are interested in how to eat healthy, train for your first (or next) marathon, take your fitness to the next level, find the best super foods, or simply want to improve your vitality through healthy, doable practices, this book will help you on your journey regardless of age or fitness level.

  • Riboswitch Discovery, Structure and Function

    • 1st Edition
    • Volume 549
    • English
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in riboswitch discovery and validation, synthesis and sample prep methods for large RNAs, riboswitch structure and function methods, folding pathways and dynamics, and ligand interactions and thermodynamics.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 67
    • English
    Volume 67 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists. The serial provides the latest and most up-to-date technologies related to the field of Clinical Chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Metal-Containing Enzymes

    • 1st Edition
    • Volume 97
    • English
    Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series is the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics.

  • Marine Faunal Diversity in India

    Taxonomy, Ecology and Conservation
    • 1st Edition
    • Krishnamoorthy Venkataraman + 1 more
    • English
    More than 70% of the earth’s surface is covered by water, making it an ideal and abundant resource for studying species diversity, faunal communities, and ecosystems. India’s massive coastline (5,044 miles) means it plays a major role in housing these faunal communities. Of the 32 animal phyla, 15 are represented in India’s marine ecosystem, covering more than 15,000 species. Marine and coastal ecosystems of India provide supporting services in the form of wide range of habitats. Major ecosystems such as estuaries, mangroves, coral reefs, lagoons, seaweeds and sea grasses serve as nurseries for both inshore and offshore fishes and others, many of which are supposed to be commercially exploited. Marine Faunal Diversity in India describes different marine faunal group ranges from sponges, corals, mollusks, crabs, fishes, reptiles, birds, marine mammals, mangrove fauna and tsunami impact on marine faunal diversity. The chapters, written by reputed experts in their respective fields, illustrate diversity and distribution of marine faunal communities. Key aspects of the ecology and conservation of this important ecosystem are also discussed. Marine Faunal Diversity in India provides marine biologists and related researchers with access to the latest research and field studies from this major region.

  • The Mediterranean Diet

    An Evidence-Based Approach
    • 1st Edition
    • Victor R. Preedy + 1 more
    • English
    The Mediterranean Diet offers researchers and clinicians a single authoritative source which outlines many of the complex features of the Mediterranean diet: ranging from supportive evidence and epidemiological studies, to the antioxidant properties of individual components. This book embraces a holistic approach and effectively investigates the Mediterranean diet from the cell to the nutritional well-being of geographical populations. This book represents essential reading for researchers and practicing clinicians in nutrition, dietetics, endocrinology, and public health, as well as researchers, such as molecular or cellular biochemists, interested in lipids, metabolism, and obesity.

  • Sertoli Cell Biology

    • 2nd Edition
    • Michael D. Griswold
    • English
    Sertoli Cell Biology, Second Edition summarizes the progress since the last edition and emphasizes the new information available on Sertoli/germ cell interactions. This information is especially timely since the progress in the past few years has been exceptional and it relates to control of sperm production in vivo and in vitro.

  • Flavour Development, Analysis and Perception in Food and Beverages

    • 1st Edition
    • J K Parker + 2 more
    • English
    Flavour is a critical aspect of food production and processing, requiring careful design, monitoring and testing in order to create an appealing food product. This book looks at flavour generation, flavour analysis and sensory perception of food flavour and how these techniques can be used in the food industry to create new and improve existing products. Part one covers established and emerging methods of characterising and analysing taste and aroma compounds. Part two looks at different factors in the generation of aroma. Finally, part three focuses on sensory analysis of food flavour.

  • Diet and Nutrition in Dementia and Cognitive Decline

    • 1st Edition
    • Colin R. Martin + 1 more
    • English
    Diet and Nutrition in Dementia and Cognitive Decline offers researchers and clinicians a single authoritative source which outlines the complex interrelationships between cognitive decline, dementia and the way diet can be modified to improve outcomes. In a cross-disciplinary field like dementia research and practice, clinicians and researchers need a comprehensive resource which will quickly help them identify a range of nutritional components and how they affect cognitive decline and the development of dementia. While the focus is on clinical applications, the book also features landmark and innovative preclinical studies that have served as the foundation of rigorous trials. Chapters explore the evidence of how nutritional components, either in the diet or supplements, can either impede the development to, or progression from, the onset of dementia. Authors investigate how conditions and processes overlap between defined conditions and present studies which show that dietary components may be equally effective in a number of conditions characterized by declining cognition or dementia. This book represents essential reading for researchers and practicing clinicians in nutrition, dietetics, geriatrics, nursing, neurology, and psychology, as well as researchers, such as neuroscientists, molecular and cellular biochemists, interested in dementia. http://www.acnr.co.u...

  • Surgical Techniques in Total Knee Arthroplasty and Alternative Procedures

    • 1st Edition
    • Saverio Affatato
    • English
    Total knee arthroplasty (TKA) is commonly considered to be a reliable procedure, with high implant survival rates at 10 to 15 years of follow-up. The goal of total knee replacement surgery is to relieve pain and obtain better knee function. This is achieved by ensuring correct patient selection, pre-operative deformity, implant design and accurate surgical techniques. This book covers a range of techniques for the realisation of functional joint motion and stability. The first part of the book will describe fundamentals in total knee arthroplasty and alternative procedures. The second half will look at surgical techniques and considerations whilst the final chapters will address future trends and challenges in the field of knee surgery. This book will be an essential reference for academics, orthopaedic surgeons, and those training in medicine, physiatry and rheumatology.

  • Advances in Agronomy

    • 1st Edition
    • Volume 128
    • English
    Advances in Agronomy continues to be recognized as a leading reference and a first-rate source for the latest research in agronomy. As always, the subjects covered are varied and exemplary of the myriad of subject matter dealt with by this long-running serial

  • Electron Beam Pasteurization and Complementary Food Processing Technologies

    • 1st Edition
    • Suresh Pillai + 1 more
    • English
    Food safety is a constant challenge for the food industry, and food irradiation technology has developed significantly since its introduction, moving from isotope irradiation to the use of electron beam technology. Electron Beam Pasteurization and Complementary Food Processing Technologies explores the application of electron beam pasteurization in conjunction with other food processing technologies to improve the safety and quality of food. Part one provides an overview of the issues surrounding electron beam pasteurization in food processing. Part two looks at different thermal and non-thermal food processing technologies that complement irradiation. Finally, a case study section on the commercial applications of e-beam processing provides examples from industry.

  • Rapid Sensory Profiling Techniques

    Applications in New Product Development and Consumer Research
    • 1st Edition
    • Julien Delarue
    • English
    Sensory analysis is an important tool in new product development. There has recently been significant development in the methods used to capture sensory perception of a product. Rapid Sensory Profiling Techniques provides a comprehensive review of rapid methods for sensory analysis that can be used as alternatives or complementary to conventional descriptive methods. Part one looks at the evolution of sensory perception capture methods. Part two focuses on rapid methods used to capture sensory perception, and part three covers their applications in new product development and consumer research. Finally, part four explores the applications of rapid methods in testing specific populations.

  • Knobil and Neill's Physiology of Reproduction

    • 4th Edition
    • Tony M. Plant + 1 more
    • English
    The Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to provide the historical context to current research, and most importantly as an aid for graduate teaching on a broad range of topics in human and comparative reproduction. In the decade since the publication of the last edition, the study of reproductive physiology has undergone monumental changes. Chief among these advances are in the areas of stem cell development, signaling pathways, the role of inflammation in the regulatory processes in the various tissues, and the integration of new animal models which have led to a greater understanding of human disease. The new edition synthesizes all of this new information at the molecular, cellular, and organismal levels of organization and present modern physiology a more understandable and comparative context.

  • Translating Gene Therapy to the Clinic

    Techniques and Approaches
    • 1st Edition
    • Jeffrey Laurence + 1 more
    • English
    Translating Gene Therapy to the Clinic, edited by Dr. Jeffrey Laurence and Michael Franklin, follows the recent, much-lauded special issue of Translational Research in emphasizing clinical milestones and critical barriers to further progress in the clinic. This comprehensive text provides a background for understanding the techniques involved in human gene therapy trials, and expands upon the disease-specific situations in which these new approaches currently have the greatest therapeutic application or potential, and those areas most in need of future research. It emphasizes methods, tools, and experimental approaches used by leaders in the field of translational gene therapy. The book promotes cross-disciplinary communication between the sub-specialties of medicine, and remains unified in theme.

  • Managing and Preventing Obesity

    Behavioural Factors and Dietary Interventions
    • 1st Edition
    • Timothy Gill
    • English
    Obesity is an increasing problem on a global scale, and strategies for its prevention involve experts from many disciplines including nutritionists, physicians, policy-makers and public health professionals. This book covers the latest advances in obesity development, management and prevention with specific focus on dietary interventions. Part one covers the development of obesity and key drivers for its continuation and increase. Part two looks at the role of specific dietary components in obesity management, and part three discusses the role of behavioural factors such as eating patterns in managing and preventing obesity. Part four focuses on structured dietary interventions for obesity treatment, and part five looks at public interventions and consumer issues.

  • Advances in Food and Beverage Labelling

    Information and Regulations
    • 1st Edition
    • Paul Berryman
    • English
    Advances in Food and Beverage Labelling reviews recent advances in labelling research and regulation, covering issues such as nutrition and hazard information, traceability, health claims and standardisation, as well as new labelling technologies and consumer issues. The EU Food Information Regulation will come into force in December 2014 and the book is designed to provide timely and useful information to manufacturers in this area, as well as on a global scale. Part one covers the different types of information that can, or must be present on a food label. Part two looks at recent developments in food labelling technology, regulations and enforcement.

  • Soil Microbiology, Ecology and Biochemistry

    • 4th Edition
    • Eldor Paul
    • English
    The fourth edition of Soil Microbiology, Ecology and Biochemistry updates this widely used reference as the study and understanding of soil biota, their function, and the dynamics of soil organic matter has been revolutionized by molecular and instrumental techniques, and information technology. Knowledge of soil microbiology, ecology and biochemistry is central to our understanding of organisms and their processes and interactions with their environment. In a time of great global change and increased emphasis on biodiversity and food security, soil microbiology and ecology has become an increasingly important topic. Revised by a group of world-renowned authors in many institutions and disciplines, this work relates the breakthroughs in knowledge in this important field to its history as well as future applications. The new edition provides readable, practical, impactful information for its many applied and fundamental disciplines. Professionals turn to this text as a reference for fundamental knowledge in their field or to inform management practices.

  • Nonviral Vectors for Gene Therapy

    Lipid- and Polymer-based Gene Transfer
    • 1st Edition
    • Volume 88
    • English
    The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.

  • Advances in Microbial Food Safety

    Volume 2
    • 1st Edition
    • J Sofos
    • English
    Research and legislation in food microbiology continue to evolve, and outbreaks of foodborne disease place further pressure on the industry to provide microbiologically safe products. This second volume in the series Advances in Microbial Food Safety summarises major recent advances in this field, and complements volume 1 to provide an essential overview of developments in food microbiology. Part one opens the book with an interview with a food safety expert. Part two provides updates on single pathogens, and part three looks at pathogen detection, identification and surveillance. Part four covers pathogen control and food preservation. Finally, part five focuses on pathogen control management.

  • Advances in Bacterial Pathogen Biology

    • 1st Edition
    • Volume 65
    • English
    This volume is an up-to-date overview of the physiology of selected pathogenic bacteria. Each chapter is written by experts in the field of that organism.The focus is on biochemistry and physiology but topics of clinical relevance are included.

  • Mitochondrial Function

    • 1st Edition
    • Volume 547
    • English
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. Methods to assess mitochondrial function is of great interest to neuroscientists studying chronic forms of neurodegeneration, including Parkinson's, Alzheimer's, ALS, Huntington's and other triplet repeat diseases, but also to those working on acute conditions such as stroke and traumatic brain injury. This volume covers research methods on how to assess the life cycle of mitochondria including trafficking, fusion, fission, and degradation. Multiple perspectives on the complex and difficult problem of measurement of mitochondrial reactive oxygen species production with fluorescent indicators and techniques ranging in scope from measurements on isolated mitochondria to non-invasive imaging of metabolic function.

  • Clinical Genomics

    • 1st Edition
    • Shashikant Kulkarni + 1 more
    • English
    Clinical Genomics provides an overview of the various next-generation sequencing (NGS) technologies that are currently used in clinical diagnostic laboratories. It presents key bioinformatic challenges and the solutions that must be addressed by clinical genomicists and genomic pathologists, such as specific pipelines for identification of the full range of variants that are clinically important. This book is also focused on the challenges of diagnostic interpretation of NGS results in a clinical setting. Its final sections are devoted to the emerging regulatory issues that will govern clinical use of NGS, and reimbursement paradigms that will affect the way in which laboratory professionals get paid for the testing.

  • Dietary Supplements

    Safety, Efficacy and Quality
    • 1st Edition
    • Katja Berginc + 1 more
    • English
    Dietary supplements made from foods, herbs and their constituents are a rapidly growing market sector. Consumers often view food supplements as ‘natural’ and therefore safe; however, supplements are regulated as foods rather than as pharmaceuticals and so are not as closely monitored as may be necessary. With the commercial market in these products growing, this book provides essential research into their safety, efficacy and potential risk of interaction with pharmaceuticals. Following an introductory chapter, part one covers the chemical composition, manufacture and regulation of dietary supplements. Part two looks at the effectiveness of different types of dietary supplement and methods of evaluation. Finally, part three focuses on supplement safety.

  • Metagenomics for Microbiology

    • 1st Edition
    • Jacques Izard + 1 more
    • English
    Concisely discussing the application of high throughput analysis to move forward our understanding of microbial principles, Metagenomics for Microbiology provides a solid base for the design and analysis of omics studies for the characterization of microbial consortia. The intended audience includes clinical and environmental microbiologists, molecular biologists, infectious disease experts, statisticians, biostatisticians, and public health scientists. This book focuses on the technological underpinnings of metagenomic approaches and their conceptual and practical applications. With the next-generation genomic sequencing revolution increasingly permitting researchers to decipher the coding information of the microbes living with us, we now have a unique capacity to compare multiple sites within individuals and at higher resolution and greater throughput than hitherto possible. The recent articulation of this paradigm points to unique possibilities for investigation of our dynamic relationship with these cellular communities, and excitingly the probing of their therapeutic potential in disease prevention or treatment of the future.

  • Practical Guide to Clinical Computing Systems

    Design, Operations, and Infrastructure
    • 2nd Edition
    • Thomas Payne
    • English
    Although informatics trainees and practitioners who assume operational computing roles in their organization may have reasonably advanced understanding of theoretical informatics, many are unfamiliar with the practical topics - such as downtime procedures, interface engines, user support, JCAHO compliance, and budgets - which will become the mainstay of their working lives. Practical Guide to Clinical Computing Systems 2nd edition helps prepare these individuals for the electronic age of health care delivery. It is also designed for those who migrate into clinical computing operations roles from within their health care organization. A new group of people interested in this book are those preparing for Clinical Informatics board certification in the US. The work provides particular differentiation from the popular first edition in four areas: 40% more content detailing the many practical aspects of clinical informatics. Addresses the specific needs of the Clinical Informatics board certification course – for which it is presently recommended by the ABPM Focus on new tech paradigms including cloud computing and concurrency – for this rapidly changing field.

  • Epigenetics and Neuroplasticity - Evidence and Debate

    • 1st Edition
    • Volume 128
    • English
    The ‘epi-(Greek for ‘over’, ‘above’)genome’, with its rich cache of highly regulated, structural modifications—includ... DNA methylation, histone modifications and histone variants—defines the moldings and three-dimensional structures of the genomic material inside the cell nucleus and serves, literally, as a molecular bridge linking the environment to the genetic materials in our brain cells. Due to technological and scientific advances in the field, the field of neuroepigenetics is currently one of the hottest topics in the basic and clinical neurosciences. The volume captures some of this vibrant and exciting new research, and conveys to the reader an up-to-date discussion on the role of epigenetics across the lifespan of the human brain in health and disease.

  • Stem Cell Biology and Tissue Engineering in Dental Sciences

    • 1st Edition
    • Ajaykumar Vishwakarma + 3 more
    • English
    Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the significance of translational research in this field in the medical sciences. It compiles basic developmental biology with keen focus on cell and matrix biology, stem cells with relevance to tissue engineering biomaterials including nanotechnology and current applications in various disciplines of dental sciences; viz., periodontology, endodontics, oral & craniofacial surgery, dental implantology, orthodontics & dentofacial orthopedics, organ engineering and transplant medicine. In addition, it covers research ethics, laws and industrial pitfalls that are of particular importance for the future production of tissue constructs. Tissue Engineering is an interdisciplinary field of biomedical research, which combines life, engineering and materials sciences, to progress the maintenance, repair and replacement of diseased and damaged tissues. This ever-emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular and cell-based technologies for clinical and non-clinical applications. As evident in numerous medical disciplines, tissue engineering strategies are now being increasingly developed and evaluated as potential routine therapies for oral and craniofacial tissue repair and regeneration.

  • Diabetes and the Nervous System

    • 1st Edition
    • Volume 126
    • Douglas W Zochodne + 1 more
    • English
    This is a unique compilation, by experts worldwide, addressing how diabetes impacts the nervous system. For example, diabetic polyneuropathy, a disorder more common than MS, Parkinson’s disease, and ALS combined, is a major source of disability to diabetic persons worldwide. This book addresses diabetic polyneuropathy and how diabetes alters other parts of the nervous system.

  • Biomaterials and Medical Device - Associated Infections

    • 1st Edition
    • L Barnes + 1 more
    • English
    Despite advances in materials and sterilisation, patients who receive biomaterials of medical device implants are still at risk of developing an infection around the implantation site. This book reviews the fundamentals of biomaterials and medical device related infections and methods and materials for the treatment and prevention of infection. The first part of the book provides readers with an introduction to the topic including analyses of biofilms, diagnosis and treatment of infection, pathology and topography. The second part of the book discusses a range of established and novel technologies and materials which have been designed to prevent infection.

  • The Use of CRISPR/cas9, ZFNs, TALENs in Generating Site-Specific Genome Alterations

    • 1st Edition
    • Volume 546
    • English
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers recent research and methods development for changing the DNA sequence within the genomes of cells and organisms. Focusing on enzymes that generate double-strand breaks in DNA, the chapters describe use of molecular tools to introduce or delete genetic information at specific sites in the genomes of animal, plant and bacterial cells.

  • Handbook of Natural Antimicrobials for Food Safety and Quality

    • 1st Edition
    • M Taylor
    • English
    Natural additives are increasingly favoured over synthetic ones as methods of ensuring food safety and long shelf-life. The antimicrobial properties of both plant-based antimicrobials such as essential oils and proteins such as bacteriocins are used in, for example, edible preservative films, in food packaging and in combination with synthetic preservatives for maximum efficacy. New developments in delivery technology such as nanoencapsulation also increase the potential of natural antimicrobials for widespread use in industry. Part one introduces the different types of natural antimicrobials for food applications. Part two covers methods of application, and part three looks at determining the effectiveness of natural antimicrobials in food. Part four focuses on enhancing quality and safety, and includes chapters on specific food products.

  • Coffee in Health and Disease Prevention

    • 1st Edition
    • Victor R. Preedy
    • English
    Coffee in Health and Disease Prevention presents a comprehensive look at the compounds in coffee, their reported benefits (or toxicity risks) and also explores them on a health-condition specific level, providing researchers and academics with a single-volume resource to help in identifying potential treatment uses. No other book on the market considers all the varieties of coffee in one volume, or takes the disease-focused approach that will assist in directing further research and studies. The book embraces a holistic approach and effectively investigates coffee and its specific compounds from the biochemical to the nutritional well-being of geographical populations. This book represents essential reading for researchers in nutrition, dietetics, food science, biochemistry, and public health.

  • Control of Plant Virus Diseases

    Seed-Propagated Crops
    • 1st Edition
    • Volume 90
    • Gad Loebenstein + 1 more
    • English
    The first review series in virology and published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews, providing a valuable overview of the field. The series of eclectic volumes are valuable resources to virologists, microbiologists, immunologists, molecular biologists, pathologists, and plant researchers. Volume 90 features articles on control of plant virus diseases.

  • Evolutionary Origins and Early Development of Number Processing

    • 1st Edition
    • Volume 1
    • David C. Geary + 2 more
    • English
    The first volume in this ground-breaking series focuses on the origins and early development of numerical cognition in non-human primates, lower vertebrates, human infants, and preschool children. The text will help readers understand the nature and complexity of these foundational quantitative concepts and skills along with evolutionary precursors and early developmental trajectories.

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