Advances in Lipid Research

Contributors to this Volume

Preface

The Metabolism of Polyenoic Fatty Acids

I. The Transformation of Oleic Acid into △5,8,11-C20-Trienoic Acid

II. The Inconvertibility of One Type of Polyenoic Acid into Another

III. The Behavior of the Isomers of Linoleic and Linolenic Acids

IV. The Combustibility of the Polyenoic Acids

Addendum: Preparation by Total Synthesis of Unsaturated, Especially Polyenoic, Fatty Acids

References

The Analysis of Human Serum Lipoprotein Distributions

I. Introduction and General Considerations of Human Serum Lipoprotein Analysis

II. Some Unique Problems of Ultracentrifugal Lipoprotein Isolation and Flotation Analysis

III. A Generalized Method for the Computer Analysis of Lipoprotein Distributions

IV. Application of Computer Analysis to a Series of Adult Normal Males and Females

V. Potential Improvements in the Computer Methodology for Lipoprotein Analysis

References

Factors Affecting Lipoprotein Metabolism

I. Introduction

II. Physical and Chemical Properties of Plasma Lipoproteins

III. Experimental Approach to Lipoprotein Structure

IV. Biosynthesis of Plasma Lipoproteins

V. Catabolism of Plasma Lipoproteins

VI. Significance of Lipoproteins in Fat Transport

VII. Concluding Remarks

References

The Action of Drugs on Phospholipid Metabolism

I. Introduction

II. Excitants and Antidepressants

III. Depressants

IV. Glycosides

V. Pharmacologically Active Phospholipids

References

Brain Sterol Metabolism

I. Introduction

II. Distribution of Sterols in the Developing Brain

III. Distribution of Cholesterol in the Adult Mammalian Brain

IV. Brain Cholesterol Metabolism

V. Brain Sterols: The Effects of Drugs

VI. Brain Cholesterol: The Effects of Malnutrition

VII. Brain Sterols: The Effects of Disease

VIII. Conclusion

References

Lipases

I. Introduction

II. Distribution of Lipases

III. Methods of Determining Lipase Activity

IV. Purification

V. Substrate Specificity and Mode of Action

VI. Factors Affecting the Velocity of Hydrolysis

VII. Lipoprotein Lipase

VIII. Summary

References

Author Index

Subject Index