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Safety, Efficacy and Quality
1st Edition - November 7, 2014
Editors: Katja Berginc, Samo Kreft
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Dietary supplements made from foods, herbs and their constituents are a rapidly growing market sector. Consumers often view food supplements as ‘natural’ and therefore safe;… Read more
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Dietary supplements made from foods, herbs and their constituents are a rapidly growing market sector. Consumers often view food supplements as ‘natural’ and therefore safe; however, supplements are regulated as foods rather than as pharmaceuticals and so are not as closely monitored as may be necessary. With the commercial market in these products growing, this book provides essential research into their safety, efficacy and potential risk of interaction with pharmaceuticals. Following an introductory chapter, part one covers the chemical composition, manufacture and regulation of dietary supplements. Part two looks at the effectiveness of different types of dietary supplement and methods of evaluation. Finally, part three focuses on supplement safety.
Reviews the design, production and regulation of dietary supplements.
Analyses the potential for pharmacokinetic and pharmacodynamics interactions between dietary supplements and pharmaceuticals.
Offers reviews of important clinical studies on the efficacy of dietary supplements for range of conditions.
R&D managers in the nutraceutical and dietary supplement sectors, healthcare professionals and academic researchers
List of contributors
Woodhead Publishing Series in Food Science, Technology and Nutrition
Part One: General issues
1: Dietary supplement labelling and health claims
1.1 Introduction: the regulatory situation in the European Union (EU)
1.2 Labelling requirements
1.3 Nutrition claims
1.4 Health claims
1.5 Borderline substances: between foods and medicine
2: Good manufacturing practice (GMP) in the production of dietary supplements
2.2 Key issues related to good manufacturing practice/good hygienic practice (GMP/GHP) implementation
2.3 Documentation of GMP
2.4 Benefits and drawbacks of GMP use in organisations
3: Analysing the composition of fortified foods and supplements: the case of vitamins
3.2 Extraction and purification methods
3.3 High performance liquid chromatography (HPLC)
3.4 Gas chromatography (GC)
3.5 Capillary electrophoresis (CE)
3.6 Spectroscopic methods
3.7 Microbiological methods
3.9 Other methods
3.10 Future trends
Part Two: Drug–supplement interactions
4: Pharmacokinetic interactions between drugs and dietary supplements: herbal supplements