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The Use of CRISPR/cas9, ZFNs, TALENs in Generating Site-Specific Genome Alterations

1st Edition, Volume 546 - November 4, 2014

Editors: Jennifer A. Doudna, Erik J. Sontheimer

Language: English
Hardback ISBN:
9 7 8 - 0 - 1 2 - 8 0 1 1 8 5 - 0
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 0 1 3 3 4 - 2

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers recent resear… Read more

The Use of CRISPR/cas9, ZFNs, TALENs in Generating Site-Specific Genome Alterations

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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers recent research and methods development for changing the DNA sequence within the genomes of cells and organisms. Focusing on enzymes that generate double-strand breaks in DNA, the chapters describe use of molecular tools to introduce or delete genetic information at specific sites in the genomes of animal, plant and bacterial cells.