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Elsevier

Books in Life sciences

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 106
    • Fidel Toldra
    • English
    Advances in Food and Nutrition Research, Volume 107 provides the latest advances on emerging bioactive compounds with putative health benefits and their controlled release and application in foods and nutraceuticals, as well as information on food technologies, including 3D printing, safety of raw materials, and viruses in foods. Chapters in this new release cover Tackling food allergens - the role of food processing on proteins’ allergenicity, Plant bioactive peptides for cardiovascular disease prevention, Caffeine and sport, Nanostructured steady-state nanocarriers for nutrients preservation and delivery, Flavor perception and health benefits of tea, Next Generation Plant-based Meat Alternatives: Sources, manufacturing and consumer acceptance, and more. Other sections cover Bioprotective cultures and bacteriocins as food preservatives and Raman Spectroscopy: principles and recent applications in Food Safety.

  • Biological Invasions and Global Insect Decline

    • 1st Edition
    • Jonatan Rodríguez + 2 more
    • English
    Biological Invasions and Global Insect Decline offers the most updated knowledge on how invasive alien species affect insect diversity worldwide. The book provides ongoing research and the most relevant information, covering the main aspects of the impact of biological invasions as well as future insights on mitigation and consequences. It discusses how the introduction of all kinds of organisms, from bacteria and plants to vertebrates, affect current declines in insect diversity. The latter portion of the book delves into existent and future monitoring and management programs, including citizen science and regenerative ecology as socio-ecological solutions to combat these threats. Written and edited by international experts on invasion ecology and insect conservation, this book explores the role of global change and the introduction of invasive species in altering the structure of habitats and how this induces a global insect decline. This will be a valuable resource for entomologists, invasion biologists and other researchers in biodiversity conservation, as well as practitioners and stakeholders concerned about problematic invasive alien species and insect population decline.

  • Pharmaceutics

    Basic Principles and Application to Pharmacy Practice
    • 2nd Edition
    • Alekha Dash + 1 more
    • English
    Pharmaceutics: Basic Principles and Application to Pharmacy Practice, Second Edition is a valuable textbook covering the role and application of pharmaceutics within pharmacy practice. This updated resource is geared toward meeting and incorporating the current curricular guidelines on pharmaceutics and laboratory skills mandated by the American Council for Pharmacy Education. It includes a number of student-friendly features, including chapter objectives and summaries, practical examples, case studies, numerous images and key-concept text boxes. Two new chapters are included, as well as a new end of chapter section covering "critical reflections and practice applications". Divided into three sections – Physical Principles and Properties of Pharmaceutics; Practical Aspects of Pharmaceutics; and Biological Applications of Pharmaceutics – this new edition covers all aspects of pharmaceutics and providing a single and compelling source for students.

  • Artificial Intelligence in Clinical Practice

    How AI Technologies Impact Medical Research and Clinics
    • 1st Edition
    • Chayakrit Krittanawong
    • English
    Artificial Intelligence in Clinical Practice: How AI Technologies Impact Medical Research and Clinics compiles current research on Artificial Intelligence within medical subspecialties, helping practitioners with diagnosis, clinical decision-making, disease prediction, prevention, and the facilitation of precision medicine. The book defines the basic concepts of big data and AI in medicine and highlights current applications, challenges, ethical issues, and biases. Each chapter discusses AI applied to a specific medical subspecialty, including primary care, preventive medicine, general internal medicine, radiology, pathology, infectious disease, gastroenterology, cardiology, hematology, oncology, dermatology, ophthalmology, mental health, neurology, pulmonary, critical care, rheumatology, surgery, and OB-GYN. This is a valuable resource for clinicians, students, researchers and members of medical and biomedical fields who are interested in learning more about artificial intelligence technologies and their applications in medicine.

  • Neurophysiology of Silence Part B: Theory and Review

    • 1st Edition
    • Volume 280
    • English
    Progress in Brain Research serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors

  • Synthesis of 5-Membered Heterocycles

    Role of DMF as Solvent, Reagent, Catalyst, and Stabilizer
    • 1st Edition
    • Navjeet Kaur
    • English
    Synthesis of Five-Membered Heterocycles: Role of DMF as Solvent, Reagent, Catalyst, and Stabilizer helps readers quickly assess possible synthetic approaches. The book's audience, researchers, academic professionals and synthetic chemists both in industry and academia will find detailed information about the synthesis of five-membered heterocyclic compounds using dimethylformamide. Over the years, heterocyclic compounds, especially five-membered, have drawn more attention of pharmaceutical community because of their therapeutic value. The formation of heterocyclic compounds has turned out to be the keystone of synthetic organic chemistry. Dimethylformamide has played an important role in organic synthesis for a long time, and it is frequently utilized as a common solvent for chemical reactions and broadly used in industry as a reagent. It is a unique chemical and can play three other roles in organic chemistry, i.e., as stabilizer, reagent and catalyst. Due to its structure, DMF can participate in several reactions as a versatile building block for several units.

  • Hormone Receptors: Structures and Functions

    • 1st Edition
    • Volume 123
    • English
    Hormone Receptors: Structures and Functions, Volume 123 in the Vitamins and Hormones series, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors.

  • Circadian System

    • 1st Edition
    • Volume 137
    • Rossen Donev
    • English
    Circadian System, Volume 137 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters that comprehensively cover Circadian Systems Genes and Their Importance for Human Health, Single nucleotide polymorphisms (SNPs) in circadian genes: Impact on Gene Function and Phenotype, Relationship between circadian rhythm and diseases: sex hormones impact, Advances in circadian clock regulation of reproduction, Disruption of the clock gene expression in central and peripheral circadian oscillators by maternal overnutrition in the Oryctolagus cuniculus, COVID-19 disease management in aspect of Circadian system, and more. Other sections cover Molecular Characterization of Circadian Gene Expression and Its Correlation with Survival Percentage in Colorectal Cancer Patients, Identifying circadian gene signature that estimates overall survival from colon adenocarcinoma, The role of environmental signals in the expression of rhythmic cardiac proteins and their influence on cardiac pathologies, and much more.

  • Breeding Disease-Resistant Horticultural Crops

    • 1st Edition
    • Paul W. Bosland + 1 more
    • English
    Breeding Disease-Resistant Horticultural Crops is a complete and comprehensive resource for understanding the concept of breeding disease resistant crops, especially horticultural crops. Breeders of horticultural crops face distinct challenges that are different from agronomy/row crops, and these crops do not benefit from the vast body of literature available for agronomic crops. This book covers the basic theories that underpin breeding for disease resistance and features extensive real-world examples. Both classical and biotechnical breeding methods are covered, with an emphasis on how these methods are adapted for horticultural species. Presented in a logical flow for the reader, this book addresses historical perspectives and context as it relates to breeding for disease resistance. It highlights treatments of resistance in the context of the phenotype, the genotype, the pathogen, the environment interaction, sources of resistance, and the deployment of resistance to obtain a durable resistance.

  • Applications of Seaweeds in Food and Nutrition

    • 1st Edition
    • Daniel Ingo Hefft + 1 more
    • English
    Applications of Seaweeds in Food and Nutrition provides an overview on the cultural, biological and engineering dimensions relating to seaweed as a food. With the need for sustainable and healthy foods growing, this comprehensive resource explores how seaweeds can deliver not only nutritional benefits, but also antiviral and antibacterial properties as a food additive and within food processing and manufacturing. Recent developments show that the use of seaweed extracts as a compound can prevent browning. It use in other areas such as a thickening and gelling agents in foods and cosmetics is also encouraging. There are hundreds of different varieties of seaweed known to mankind, yet very little literature is available on the processing of these "crops." This book provides these valuable and practical insights.

  • Computer-Aided Applications in Pharmaceutical Technology

    Delivery Systems, Dosage Forms, and Pharmaceutical Unit Operations
    • 2nd Edition
    • Jelena Duris
    • English
    Computer-Aided Applications in Pharmaceutical Technology: Delivery Systems, Dosage Forms, and Pharmaceutical Unit Operations, Second Edition covers the fundamentals of experimental design application and interpretation in pharmaceutical technology, chemometric methods with an emphasis on their applications in process control, neural computing, data science, computer-aided biopharmaceutical characterization, as well as the application of computational fluid dynamics in pharmaceutical technology. Completely updated, the book introduces the theory and practice of computational tools through new case studies. Chapters cover Quality by Design in pharmaceutical development, overview data mining methodologies, present computer-aided formulation development, cover experimental design applications, and much more.

  • Resident Stem Cells and Regenerative Therapy

    Sources and Clinical Applications
    • 2nd Edition
    • Regina Coeli dos Santos Goldenberg + 1 more
    • English
    Resident Stem Cells and Regenerative Therapy: Sources and Clinical Applications, Second Edition presents the main findings to date and the important factors to be considered when contemplating resident stem cells in regenerative therapies. Chapters on cardiac, brain, neural, liver, kidney, skeletal muscle, bone, pancreatic, skin and lung resident stem cells will assist in defining the level of success that has been achieved and the direction for the road ahead. With contributions from leading laboratories, open questions related to resident stem cells and regenerative therapies will also be presented for debate. In the last several decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the complexity of organ structures.

  • Active Learning for Digital Transformation in Healthcare Education, Training and Research

    • 1st Edition
    • Miltiadis D. Lytras + 1 more
    • English
    Active Learning for Digital Transformation in Healthcare Education, Training and Research discusses the potential of advanced training of health professionals as a contributing factor to improve treatment outcomes. By reading this book, professionals who deal with patients with low health literacy will be prepared to promote better access to digital tools, understand the habits of users of health services, and empower engagement. The book contains a set of techniques and instruments associated with health literacy, communication skills and personal development that will enable their application in good daily practices and assist healthcare professionals to promote digital transformation to patients. This is a valuable resource for researchers, graduate students and healthcare professionals who are interested in learning more about how they can be an effective agent of change in healthcare.

  • Intelligence-Based Cardiology and Cardiac Surgery

    Artificial Intelligence and Human Cognition in Cardiovascular Medicine
    • 1st Edition
    • Anthony C. Chang + 4 more
    • English
    Intelligence-Based Cardiology and Cardiac Surgery: Artificial Intelligence and Human Cognition in Cardiovascular Medicine provides an especially timely multidisciplinary and comprehensive survey of artificial intelligence concepts and methodologies. It includes real-life applications in adult and pediatric cardiovascular medicine, spanning the life span from fetus to adult. Led by a senior cardiologist–data scientist and supported by renowned data scientists and cardiac clinicians with an ardent passion for artificial intelligence in cardiovascular medicine, the book provides a clinical interface between the medical and data science domains that is symmetric and realistic.The content consists of basic concepts and applications of artificial intelligence and human cognition in cardiology and cardiac surgery. This portfolio ranges from big data to machine and deep learning, as well as cognitive computing and natural language processing in cardiac disease states such as heart failure, hypertension, and pediatric cardiac care. Artificial intelligence tools are described from the intensive care unit setting to other venues, such as the outpatient clinic, catheterization laboratory, and operating room. Future applications in related areas, such as large language models, extended reality, and digital twins, are also discussed. The book encompasses more than 50 chapters written by cardiologists or cardiac surgeons. Each chapter provides sections on the current state of the art and future directions and concludes with major takeaways. A robust compendium of practical resources, such as a comprehensive glossary, best references, and other resources, is also included.The book narrows the knowledge and expertise chasm between data scientists, cardiologists, and cardiac surgeons, inspires these clinicians to embrace artificial intelligence methodologies, and educates data scientists about the cardiac ecosystem to create a transformational paradigm for cardiovascular healthcare that improves patient outcomes.

  • Handbook of Current and Novel Protocols for the Treatment of Infertility

    • 1st Edition
    • Michael H. Dahan + 3 more
    • English
    The field of Assisted Reproductive Technology (ART) is rapidly evolving and stimulation protocols, fertility strategies and aspects of infertility treatments are constantly being updated as advances and new discoveries are made.Handbook of Current and Novel Protocols for the Treatment of Infertility is a valuable resource of well-organized, comprehensive scientific data with practical guides and step-by-step protocols for infertility management. Written by world-wide experts, this book discusses different practice patterns and approaches used internationally and presents innovative topics including preimplantation genetic testing, time lapse imaging and the role of artificial intelligence in ART.This book provides up-to-date, evidence-based guidance on daily practice and is an important resource for infertility providers, including trainees or experienced clinicians, embryologist, and is geared for both specialist in reproductive medicine and gynecologists interested in increasing their knowledge in the field of reproductive endocrinology and intertility.

  • Our Genes, Our Choices

    How Genotype and Gene Interactions Affect Behavior
    • 2nd Edition
    • David Goldman
    • English
    Our Genes, Our Choices: How Genotype and Gene Interactions Affect Behavior, Second Edition explains how the complexity of human behavior, including concepts of free will, derives from a relatively small number of genes which direct neurodevelopmental sequences. Are people free to make choices or do genes determine behavior? Paradoxically, the answer to both questions is "yes," because of neurogenetic individuality, a new theory with profound implications. Here, author David Goldman uses judicial, political, medical, and ethical examples to illustrate that this lifelong process is guided by individual genotype, molecular and physiologic principles, as well as by randomness and environmental exposures.Written in an authoritative yet accessible style, the book includes practical descriptions of the function of DNA, discusses the scientific and historical bases of genethics, and introduces the topics of epigenetics and the predictive power of behavioral genetics.

  • Ethics for Health Promotion and Health Education

    • 1st Edition
    • Jody Vogelzang
    • English
    Ethics for Health Promotion and Health Education discusses ethical principles and interpretations by classical ethicists as they apply to health promotion and health education. The book unpacks ethical expectations in promoting and teaching health in both the classroom and as a researcher or practitioner and then applies the code of ethics using case study methods throughout. This informative text was written by health educators and practitioners to assist health educator and practitioner communities.

  • Acrylamide in Food

    • 2nd Edition
    • Vural Gokmen + 1 more
    • English
    Acrylamide in Food, Second Edition, is fully updated with four new chapters that incorporate current literature on acrylamide, including analysis, formation mechanisms, levels in foods, reduction strategies, and new regulations, such as the one made by the European Union in 2017 regarding the presence of acrylamide in processed foods. The book comprises of four parts: part one introduces acrylamide and the food chain in the context of harm and health. Part two focusses on acrylamide in various types of foods, such as bakery products, fried potato products, coffee, battered products, water, table olives, etc. Part three highlights its interaction mechanisms and health effects. Part four discusses methods of analysis. Acrylamide in Food, Second Edition is edited by a team of international experts in the field and is a quality reference in the developing field of acrylamide in food. It is valuable to researchers in the food industry or working on evaluating the factors affecting the formation of acrylamide in different heat-treated foods and the possibilities of reducing acrylamide formation accordingly.

  • Nanostructured Materials

    Physicochemical Fundamentals for Energy and Environmental Applications
    • 1st Edition
    • Zesheng Li + 1 more
    • English
    Nanostructured Materials: Physicochemical Chemistry Fundamentals for Energy and Environmental Applications summarizes research knowledge and helps advanced students, researchers and industrial technicians understand specific applications of nanomaterials in energy and the environment. Sections bring a strong foundational focus on the physicochemical basis of nanomaterials for these applications, the basic theory and physicochemical basis of nanomaterials, an energy and environment applications examination of typical cases, and progress. This book will appeal to researchers in the chemical sciences (inorganic and physical chemistry, coordination chemistry, molecular dynamics, electrochemistry, photocatalysis, thermocatalysis, thermodynamics, etc.), nanoscience (graphene, carbon nanotubes, nanocrystals, nano catalysis, energy, and environment-nano science), and more. Efficient use of energy, eco-friendly environmental systems, and technologies play an important role in global sustainable development. Multifunctional nanocomposites have excellent properties and can meet the practical needs of energy development and environmental treatment. They have been gradually applied in chemical materials, energy preparation, pollution control and other fields and have achieved impressive development.

  • Stem Cell in Medicine

    • 1st Edition
    • Volume 199
    • English
    **Association of American Publishers (AAP) PROSE Award Finalist in Biomedicine and Neuroscience, 2024**Stem Cells in Medicine, Volume 199 in the Progress in Molecular Biology and Translational Science series, provides the most topical and informative research in the field of stem cells. Sections in this new release update on an Introduction to stem cells, Stem cell engineering, Xeno-free culture and proliferation of hPSCs on 2D biomaterials, 3D scaffold preparation for stem cell culture and differentiation, GMP grade production of hPSCs, Human hepatic stem cell assay, Cardiomyocyte cell sheets derived from hPSCs and muscle cells for myocardial infarction treatment, Stem cell therapy for osteoarthritis, hPSC-derived RPE transplantation for the treatment of macular degeneration, and much more.The book provides not only fundamental aspects and cultural and production methods of stem cells, but also the critical engineering aspects of stem cells such as drug screening using hepatocytes and disease treatment by transplantation of retinal pigment epithelium and cardiomyocytes which are derived from human pluripotent stem cells.

  • Advances in Parasitology

    • 1st Edition
    • Volume 122
    • David Rollinson + 1 more
    • English
    Advances in Parasitology, Volume 122, the latest release in this ongoing series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history.

  • ZIP Metal Ion Transporters

    • 1st Edition
    • Volume 687
    • English
    ZIP Metal Ion Transporters, Volume 684 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics, including Biochemistry, Biophysics and Structural Biology, Structure determination of a bacterial ZIP in lipidic cubic phase, Cell-based metal transport assay for animal and plant ZIPs, Measurement of metal binding affinity and transport activity in ZIP transporters using spectroscopic methods, Considerations in production of the (prokaryotic) ZIP family transporters for structural and functional studies, Metal-protein interactions investigated using model systems: thermodynamic, spectroscopic and computational methods, and more. Additional chapters cover Getting Zinc Into and Out of Cells, In-silico modeling of ZIP9 (TBD), Cellular Function and Regulation, Methods to visualize zinc transporter proteins of the SLC39A family in cells, Assessing metal ion transporting activity of ZIPs: intracellular zinc and iron detection, In vitro studies for studying manganese transport and homeostasis, and much more.

  • Advances in Cancer Research

    • 1st Edition
    • Volume 160
    • English
    Advances in Cancer Research, Volume 160, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research, with this updated edition covering PFKP: More Than Phosphofructokinase, Setting sail: maneuvering SHP2 activity and its effects in cancer, Mechanical factors driving cancer progression, Microsomal Glutathione Transferase 1 in Cancer and the Regulation of Ferroptosis, Lnc-ing epigenetic mechanisms with autophagy and cancer drug resistance, Head and Neck Cancer Treatment in the Era of Molecular Medicine, Applications of Tissue-Specific and Cancer-Selective Gene Promoters for Cancer Diagnosis and Therapy, and more.

  • Epigenetic Regulation of Cancer - Part A

    • 1st Edition
    • Volume 380
    • English
    Epigenetic Regulation of Cancer - Part A, Volume 380 in the International Review of Cell and Molecular Biology series, presents content from various experts in epigenetics who cover multiple facets of cancer-associated epigenetic alterations, including the impact of epigenetic deregulation in all steps of oncogenesis as well as promising strategies to therapeutically target cancer-associated epigenetic deregulation. Specific chapters cover Epigenetic regulation of epithelial-mesenchym... transition during cancer development, Novel insights into DNA methylation-based epigenetic regulation of breast tumor angiogenesis, Super-enhancer landscape rewiring in cancer: The epigenetic control at distal sites, Non-coding RNAs in the epigenetic landscape of Cutaneous T-cell lymphoma, and much more.

  • Metalloenzymes

    From Bench to Bedside
    • 1st Edition
    • Claudiu T. Supuran + 1 more
    • English
    Metalloenzymes: From Bench to Bedside offers a thorough overview of metalloenzymes, spanning biochemical and structural features, pharmacology, and biotechnological applications. After a brief overview, international experts in the field discuss a wide range of magnesium, calcium, zinc, manganese, nickel, iron, copper, cadmium, molybdenum, and tungsten enzymes, along with catalytic roles within their active sites. With a uniform approach throughout, each chapter includes the structure and function of the enzyme, physiologic and pathologic roles, inhibitors and activators of the enzyme (and their design), and clinical agents or compounds applied in medicine and drug discovery. This book enables scientists across academia and industry to adopt ongoing metalloenzyme research, and continuous discovery of novel metalloenzymes, in new life science studies and clinical applications.

  • Bone Cell Biomechanics, Mechanobiology and Bone Diseases

    • 1st Edition
    • Ai-Rong Qian + 1 more
    • English
    Bone Cell Biomechanics, Mechanobiology and Bone Diseases provides a comprehensive overview of recent knowledge and advances of bone cell biomechanics and related bone diseases, highlighting the cellular basis for bone responding to mechanical stimuli. The book not only provides a general overview of bone cell biology, but also the most recent advances of bone cell biomechanics, mechanobiology, the relationship between bone cell biomechanics and bone diseases, as well as the underlying mechanism. This will be useful in understanding the role of mechanobiology in bone health and bone diseases, as well for investigating novel strategies for diagnosis and therapy of bone diseases. Cells covered in the book include osteocyte, BM-MSC, osteoblast, osteoclast and chondrocyte. Cone diseases covered are osteoporosis, scoliosis and osteoarthritis. This comprehensive reference is written for researchers, scientists, clinicians and students.

  • Brain and Crime

    • 1st Edition
    • Volume 197
    • Hanna Swaab + 1 more
    • English
    Brain and Crime, Volume 197 reviews the relation between brain function and aggressive and rule-breaking (criminal) behavior. The book's focus is on the violation of social rules and not on violation of regulations that are different in different counties. It discusses the development of this behavior from childhood into adulthood, along with the mechanisms associated with the risk for aggression and rule-breaking behavior. In addition, it explores from a behavioral level concepts like psychopathology, syndrome and concepts from law, such as crime, defendant and offender. Finally, sections explore brain function, including emotion, cognitive processes, and decision-making. From the perspective of brain structure, the book covers brain networks and brain disorders. In genetics, the book includes the influence of genes and the mechanisms of epigenetics. All chapters are intended to provide information for use in the diagnosis and treatment of disorders, and in assessment and prevention.

  • History of Food and Nutrition Toxicology

    • 1st Edition
    • Esther Haugabrooks + 1 more
    • English
    **Selected for Doody’s Core Titles® 2024 in Nutrition**History of Food and Nutrition Toxicology, part of the History of Toxicology and Environmental Health series, provides an overview of history in the field to help readers better understand future applications for evaluating newer and valuable approaches and their impacts on human health. The book explores issues associated with chemical contaminants, toxicants, the use of dietary supplements and pharmaceuticals, and increasing concerns surrounding food toxicity and safety. The addition of historical case studies and end-of chapter questions make the book ideal for toxicologists, food scientists, pharmaceutical scientists, and other researchers who want to understand current state and future challenges in the field.

  • Foundations of the Mind, Brain, and Behavioral Relationships

    Understanding Physiological Psychology
    • 1st Edition
    • Jahangir Moini + 2 more
    • English
    Foundations of the Mind, Brain, and Behavioral Relationships: Understanding Physiological Psychology is an engaging introduction into neuroscience, and the portions of the nervous system, perception, and the clinical considerations in physiological psychology. "Clinical Applications" appear throughout the chapters and provide real-world examples of brain–behavior relationships, and how the nervous system interacts with other body systems to create a specific behavior. Creating an interactive experience for learners, this volume connects the study of neuroanatomy and neurophysiology with clinically relevant topics, ranging from stress and eating disorders to substance abuse, major affective disorders, and schizophrenia. Integrating the foundations of neuroscience with disorders encountered in clinical practice serves as a foundation to better understand the clinical bases of these conditions. Coauthored by clinical neuropsychologists, this book is for those interested in learning about the underpinnings of the mind, brain, and human behaviors in normal and divergent functioning.

  • Modeling of Post-Myocardial Infarction

    ODE/PDE Analysis with R
    • 1st Edition
    • William E. Schiesser
    • English
    Modeling of Post-Myocardial Infarction: ODE/PDE Analysis with R presents mathematical models for the dynamics of a post-myocardial (post-MI), aka, a heart attack. The mathematical models discussed consist of six ordinary differential equations (ODEs) with dependent variables Mun; M1; M2; IL10; Tα; IL1. The system variables are explained as follows: dependent variable Mun = cell density of unactivated macrophage; dependent variable M1 = cell density of M1 macrophage; dependent variable M2 = cell density of M2 macrophage; dependent variable IL10 = concentration of IL10, (interleuken-10); dependent variable Tα = concentration of TNF-α (tumor necrosis factor-α); dependent variable IL1 = concentration of IL1 (interleuken-1). The system of six ODEs does not include a spatial aspect of an MI in the cardiac tissue. Therefore, the ODE model is extended to include a spatial effect by the addition of diffusion terms. The resulting system of six diffusion PDEs, with x (space) and t (time) as independent variables, is integrated (solved) by the numerical method of lines (MOL), a general numerical algorithm for PDEs.

  • Neuroethics and Neurodevelopment

    • 1st Edition
    • Volume 6
    • English
    This volume focuses on topics at the intersection between neuroethics and neurodevelopment, and brings together the perspectives of experts in both clinical assessment and intervention, and researchers in child psychology, neurosciences, medicine, health policy, law, and social work. The goal is to review emerging issues related to the ethical ramifications of how variation in human neurodevelopment is described, and the effects of these descriptions on those with lived experience, clinical and intervention services, and health and social policy. Related topics are also explored including the effect of the Covid-19 pandemic, the ethics of invasive neurotechnology interventions, biomarkers, machine learning, precision medicine.

  • Modern Intervention Tools for Rehabilitation

    • 1st Edition
    • Meena Gupta + 2 more
    • English
    Modern Intervention Tools for Rehabilitation addresses current advancements in rehabilitation to better equip clinicians and researchers in the field. This resource will equip professionals for better patient outcomes and improve future rehabilitation research quality. An interdisciplinary understanding of the rehabilitation field is crucial for improved patient care and outcomes, with relevance to patient care in other disciplines as well. With chapters dedicated to diagnostics, choosing appropriate techniques, managing medical treatment, and proper equipment care, readers will be well-equipped to decide on protocols, increase patient outcomes, and improve quality of life.

  • Stress: Immunology and Inflammation

    Handbook of Stress Series Volume 5
    • 1st Edition
    • George Fink
    • English
    Volume Five in the Handbook of Stress series offers comprehensive cover of the interactions between stress, the immune system, immune responses, and Inflammation. The volume provides easy and in-depth access to these themes, both for research and clinical practice.There have been significant advances in our understanding of the interaction of stress, inflammation and the immune response to viral, bacterial and other challenges. Integrated closely with new behavioral findings and relevant to human conditions, this volume offers readers cutting-edge information of prime interest for neuroscientists, psychiatrists, neurologists, neuroendocrinologist... endocrinologists immunologists and general physicians, and researchers, and students, in similar and related themes.The Handbook of Stress series, comprised of self-contained volumes that each focus on a specific stress area, covers the significant advances made since the publication of Elsevier’s Encyclopedia of Stress (2000 and 2007). Volume 5 is ideal for graduate students, post-doctoral fellows, faculty, and clinicians interested in the interactions between stress, the immune system and inflammation.

  • Deprescribing and Polypharmacy in an Aging Population

    • 1st Edition
    • Ali Elbeddini
    • English
    Deprescribing and Polypharmacy in an Aging Population supports healthcare professionals across global healthcare institutions in reducing polypharmacy-related drug replated problems (DRPs) by working with patients, families, interprofessional healthcare professionals, and educational institutions to develop, implement, test, improve upon, and educate on strategies for deprescribing and optimizing patient safety. Polypharmacy, the use of multiple medications at the same time by one person, is very common in various patient populations, including those who lack primary physicians, patients with mental health conditions, patients with multiple chronic conditions, and in the aging population.

  • Motor System Disorders, Part II

    Spinal Cord, Neurodegenerative, and Cerebral Disorders and Treatment
    • 1st Edition
    • Volume 196
    • David S. Younger
    • English
    Motor System Disorders, Volume 196, Part Two, Spinal Cord, Neurodegenerative, and Cerebral Disorders and Treatment provides a comprehensive review of research and best practice clinical management of spinal cord, neurodegenerative, and cerebral disorders. Encompassing hereditary and acquired disorders from disease and accident, the book explores motor control disorders associated with stroke, dementia, seizure, encephalitis, and more. Covering disorders of both children and adults, the book discusses the latest advances in treatments related to neuroplasticity, neural tissue transplantation, and immunotherapy.

  • Quantitative Perfusion MRI

    Techniques, Applications and Practical Considerations
    • 1st Edition
    • Volume 11
    • Hai-Ling Margaret Cheng + 1 more
    • English
    Quantitative Perfusion MRI: Techniques, Applications, and Practical Considerations, Volume 11 clearly and carefully explains the basic theory and MRI techniques for quantifying perfusion non-invasively in deep tissue, covering all aspects of perfusion imaging, from acquisition requirements to selection of contrast agents and appropriate pharmacokinetic models and for reliable quantification in different diseases and tissue types. Specifically, this book enables the reader to understand what microvascular functional parameters can be measured with perfusion MRI, learn the basic techniques to measure perfusion in different organs, apply the appropriate perfusion MRI technique to the organ of interest, and much more. This complete reference on quantitative perfusion MRI is highly suitable for both early and experienced researchers, graduate students and clinicians wishing to understand how quantitative perfusion MRI can apply to their application area of interest.

  • Advances in Agronomy

    • 1st Edition
    • Volume 182
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 182, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Celiac Disease

    • 1st Edition
    • Volume 179
    • English
    **Selected for 2026 Doody's Core Titles in Gastroenterology**Ce... Disease, Volume 179 in the Methods in Cell Biology series is composed of extensive protocols about novel and widely used techniques for celiac disease research. Topics covered in this volume include Pepsin trypsin digested gliadin treatment of intestinal cells in vitro, Ex vivo Gliadin Stimulation of Intestinal Cells, Measuring intestinal permeability in celiac disease ex vivo using Ussing chambers, Intestinal permeability assessment using lactulose and mannitol, In vivo sensitization to gliadin by oral administration, Separation of epithelial and immune cells from intestinal biopsy samples, Isolation and study of dendritic cells and macrophages from human intestinal samples, Gnobiotic mouse models to study gluten sensitivity, and more.Other sections in this new release include In vitro differentiation of macrophages from peripheral blood cells of celiac patients, Assessment of activated gut-homing CD8+ T cells in blood by flow cytometry during a three-day gluten challenge, Isolation, cryopreservation and thawing of peripheral blood mononuclear cells for downstream applications, and more.

  • Nucleic Acids

    A Natural Target for Newly Designed Metal Chelate Based Drugs
    • 1st Edition
    • Irshad Ul Haq Bhat + 1 more
    • English
    Nucleic Acids: A Natural Target for Newly Designed Metal Chelate Based Drugs discusses how human diseases are becoming more costly to treat, along with updates on the resistance offered by disease-causing agents. The abundance of drugs in the market has provided great relief to patients, but side effects can destroy the immune system of the body. Patients need to boost their immune system, and at the same time cover expenses incurred to cure disease. Thus, a paradigm shift is needed to design a drug molecule with low cost and easy availability. Metal complexes can be a great example of such a shift, as metal ions are components of biological molecules and can achieve good binding capability to specific targets while not allowing them to damage healthy cell system. Therefore, in this book, a comprehensive compilation of recent data is provided, including the structural elucidation of metal complexes by advanced techniques and the binding pattern of metal complexes with specific targets.

  • Artificial Intelligence, Machine Learning, and Deep Learning in Precision Medicine in Liver Diseases

    Concept, Technology, Application and Perspectives
    • 1st Edition
    • Tung-Hung Su + 1 more
    • English
    Artificial Intelligence, Machine Learning, and Deep Learning in Precision Medicine and Liver Diseases: Concept, Technology, Application, and Perspectives combines four major applications of artificial intelligence (AI) within the field of clinical medicine specific to liver diseases: radiology imaging, electronic health records, pathology, and multiomics. The book provides a state-of-the-art summary of AI in precision medicine in hepatology, clarifying the concept and technology of AI and pointing to the current and future applications of AI within the field of hepatology. Coverage includes data preparation, methodology and application within disease-specific cases in fibrosis, viral and steatohepatitis, cirrhosis, hepatocellular carcinoma, acute liver failure, liver transplantation, and more. The ethical and legal issues of AI and future challenges and perspectives are also discussed. By highlighting many new AI applications which can further research, diagnosis, and treatment, this reference is the perfect resource for both practicing hepatologists and researchers focused on AI applications in medicine.

  • Emotional AI and Human-AI Interactions in Social Networking

    • 1st Edition
    • Muskan Garg + 1 more
    • English
    Emotional AI and Human-AI Interactions in Social Networking makes readers aware of recent progress in this integrated discipline. Filling the existing vacuum in research in artificial intelligence with the application of social science, this book provides in-depth knowledge of human-AI interactions with social networking and increased use of the internet. Chapters integrating Emotional Artificial Intelligence, examining behavioral interventions, compassion, education, and healthcare, as well as social cognitive networking, including social brain networks, play a pivotal role in enhancing interdisciplinary studies in the field of social neuroscience and Emotional AI. This volume is a must for those wanting to dive into this exciting field of social neuroscience AI.

  • Multi-system Imaging Spectrum associated with Neurologic Diseases

    • 1st Edition
    • Bo Gao + 1 more
    • English
    Multi-System Imaging Spectrum associated with Neurologic Diseases covers over 200 classic multi-systemic entities associated with neurologic diseases with detailed discussion alongside illustrative photos for memory aids and clarification. Accompanying text explains the history and meaning of the descriptive or metaphoric sign. Uniquely written from a practical point of view, each case leads you through a radiology expert’s thought process in analyzing imaging pitfalls of different organs or systems. The cases highlight clinical presentation, relevant pathology, anatomy, physiology, and pertinent imaging features of common disease processes. Key information is distilled succinctly, with bulleted, detailed illustrations and images.

  • Smart Diagnostics for Neurodegenerative Disorders

    Neuro-sensors
    • 1st Edition
    • Arpana Parihar + 2 more
    • English
    Smart Diagnostics for Neurodegenerative Disorders: Neuro-sensors explores all available biosensor-based approaches and technologies as well as their use in the diagnosis, prognosis and therapeutic management of a variety of neurological disorders such as Alzheimer's, Parkinson's and epileptic disorders. The book also discusses contemporary and revolutionary biosensor platforms that are being used to produce a quantitative quick lab-on-a-chip point-of-care (POC) assay for several types of predictive and diagnostic biomarkers linked with neurodegenerative disorders. It offers a combinatorial strategy for learning recent advances and designing new biosensor-based technologies in the fields of medical science, engineering and biomedical technology. Early detection of neurological conditions has the potential to treat the disease and extend the life expectancy of patients. Recent improvements in biosensor-based approaches that target specific cell surface biomarkers can be used for early detection of neurodegenerative disease.

  • Ecophysiology of the European Green Crab (Carcinus maenas) and Related Species

    Mechanisms Behind the Success of a Global Invader
    • 1st Edition
    • Dirk Weihrauch + 1 more
    • English
    Ecophysiology of the Green Shore Crab (Carcinus maenas) and Related Species: Mechanisms Behind the Success of a Global Invader provides an in-depth perspective of this devastatingly invasive coastal species. During the last 175 years, Carcinus maenas has spread around the globe by human activities. Because of its ability to flourish in a wide variety of ecosystems and outcompete native species it has been listed as one of the top 100 worst global invaders. Written by international experts, this book focuses on Carcinus maenas and discusses other brachyurans with similar physiologies as comparisons, including control systems and mechanisms used. This book serves as a valuable resource for researchers in marine biology and invasive biology, as well as for university lecturers, government or environmental agencies.

  • Artificial Intelligence in Tissue and Organ Regeneration

    • 1st Edition
    • Chandra P. Sharma + 2 more
    • English
    Artificial Intelligence in Tissue and Organ Regeneration discusses the role of artificial intelligence as a highly sought-after technology in the area of organ and tissue regeneration. Certain groups have made significant progress in mass producing mini organs and organoids from stem cells utilizing such techniques. As time goes on, there will be a need to improve these procedures, protocols, regulatory guidelines, and their clinical implications.

  • Atlas of Thoracoscopic Anatomical Pulmonary Subsegmentectomy

    • 1st Edition
    • Liang Chen + 2 more
    • English
    Atlas of Thoracoscopic Anatomical Pulmonary Subsegmentectomy provides an in-depth and comprehensive overview and guidance on anatomical pulmonary subsegmentectomy, from both theoretical and technical perspectives. The book is divided in two parts: Part I is dedicated to theoretical background of surgery, including surgical subsegmental anatomy, CT three-dimensional reconstruction of pulmonary structures, surgical techniques, and perioperative patient management. Part II presents more than 40 kinds of subsegmentectomies of the left and right lungs, both upper and lower lobes. As the rapid development of three-dimensional computed tomographic images has made it possible to provide more refined individualized anatomic details, and has consequently enabled advances in pulmonary subsegmentectomy, this book is a valuable resource to thoracic surgeons and physicians interested in thoracic surgery and mini-invasive surgical approaches in the thorax.

  • Pharmaceutical Care in Digital Revolution

    Blending Digital with Human Innovation
    • 2nd Edition
    • Ardalan Mirzaei + 1 more
    • English
    Pharmaceutical Care in the Digital Revolution: Blending Digital with Human Innovation, Second Edition provides readers with an updated view on how to use technology to improve pharmaceutical care (PC) and enhance drug outcomes with digital tools. Organized into four parts, including Global Healthcare Systems Under Pressure, Digital Advances to Innovate Pharmaceutical Care Journeys, Conditions to Drive Combinatoric Pharma-Digital Innovation, and What to do Tomorrow as a Pharmaceutical Care Leader, the book further examines digital developments that will optimize the PC process and prepare stakeholders for a dynamic future that will optimize the life of patients against a sustainable cost model. This edition also discusses recent advances in the digital health arena that will change the way we approach healthcare and prevention while also providing interactive links to lectures and technologies, tutorials on how to implement advances in your own working environment, and examples of pharmacists who are successful in building synergy between digital and pharma.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 124
    • Geoffrey M. Gadd + 1 more
    • English
    Advances in Applied Microbiology, Volume 124 continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • Handbook of Child and Adolescent Psychology Treatment Modules

    Personalized Care in Behavior and Emotion
    • 1st Edition
    • Lara Jean Farrell + 2 more
    • English
    Handbook of Child and Adolescent Psychology Treatment Modules: Personalized Care in Behavior and Emotion provides clinicians with modularized treatment strategies for commonly occurring child and youth mental health disorders. Divided into two sections, the first part of the book translates basic science into clinical practice, reviewing predictors, mediators and moderators of change, and an overview of evidence for best practices in treating disorders. The second section guides clinicians on how to implement treatment strategies. Chapters instruct what therapy is, how to introduce it to clients, step-by-step implementation, worksheets for use in practice, homework to send home with clients, and more.

  • Phospholipases in Physiology and Pathology

    • 1st Edition
    • Sajal Chakraborti
    • English
    Phospholipases in Physiology and Pathology presents a comprehensive overview on the physiology and pathology of phospholipases. This seven-volume set considers the biochemical and molecular mechanisms of normal and abnormal cell function upon dysregulation of phospholipases in different diseases. Volumes cover signal transduction mechanisms, implications in cancer, infectious diseases, neural diseases, cardiovascular diseases and other diseases, implications in inflammation, apoptosis, gene expression and non-coding RNAs, the role of natural and synthetic compounds, and stem cell therapies, nanotechnology-based therapies, and more. Together, these volumes give researchers critical insight on the mechanistic and therapeutic aspects of phospholipases.

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