Synthesis of 5-Membered Heterocycles
Role of DMF as Solvent, Reagent, Catalyst, and Stabilizer
- 1st Edition - September 14, 2023
- Latest edition
- Author: Navjeet Kaur
- Language: English
Synthesis of Five-Membered Heterocycles: Role of DMF as Solvent, Reagent, Catalyst, and Stabilizer helps readers quickly assess possible synthetic approaches. The book's audience,… Read more
Synthesis of Five-Membered Heterocycles: Role of DMF as Solvent, Reagent, Catalyst, and Stabilizer helps readers quickly assess possible synthetic approaches. The book's audience, researchers, academic professionals and synthetic chemists both in industry and academia will find detailed information about the synthesis of five-membered heterocyclic compounds using dimethylformamide. Over the years, heterocyclic compounds, especially five-membered, have drawn more attention of pharmaceutical community because of their therapeutic value. The formation of heterocyclic compounds has turned out to be the keystone of synthetic organic chemistry.
Dimethylformamide has played an important role in organic synthesis for a long time, and it is frequently utilized as a common solvent for chemical reactions and broadly used in industry as a reagent. It is a unique chemical and can play three other roles in organic chemistry, i.e., as stabilizer, reagent and catalyst. Due to its structure, DMF can participate in several reactions as a versatile building block for several units.
- Includes comprehensive descriptions of heterocycle synthesis
- Highlights many methods for the synthesis of five-membered heterocyclic compounds using dimethylformamide
- Helps readers quickly assess possible synthetic approaches
1.1 Introduction
1.2 Synthesis of pyrroles
References
2: Synthesis of fused pyrroles
2.1 Introduction
2.2 Synthesis of pyrroles fused with five-membered heterocycles
2.3 Synthesis of pyrroles fused with six-membered heterocycles
References
3: Synthesis of isoindoles and indoles
3.1 Introduction
3.2 Synthesis of isoindoles
3.3 Synthesis of indoles
References
4: Synthesis of fused indoles
4.1 Introduction
4.2 Synthesis of fused indoles
4.3 Synthesis of indoles fused with benzene
4.4 Synthesis of indoles fused with five-membered heterocycles
4.5 Synthesis of indoles fused with six-membered heterocycles
4.6 Synthesis of indoles fused with higher-membered heterocycles
References
5: Synthesis of indolizines and azaindoles
5.1 Introduction
5.2 Synthesis of indolizines
5.3 Synthesis of azaindoles
References
6: Synthesis of pyrazoles
6.1 Introduction
6.2 Synthesis of pyrazoles
6.3 Synthesis of fused pyrazoles
References
7: Synthesis of imidazoles and benzimidazoles
7.1 Introduction
7.2 Synthesis of imidazoles
7.3 Synthesis of fused imidazoles
7.4 Synthesis of benzimidazoles
7.5 Synthesis of fused benzimidazoles
References
8: Synthesis of triazoles, benzotriazoles, and tetrazoles
8.1 Introduction
8.2 Synthesis of triazoles from sodium azide
8.3 Synthesis of triazoles from trimethylsilyl azide
8.4 Synthesis of triazoles from azides
8.5 Synthesis of triazoles from diazo compounds
8.6 Synthesis of benzotriazoles
8.7 Synthesis of fused triazoles
8.8 Synthesis of tetrazoles from sodium azide
References
9: Synthesis of furans, benzofurans, and dioxolanes
9.1 Introduction
9.2 Synthesis of furans
9.3 Synthesis of benzofurans
9.4 Synthesis of fused furans
9.5 Synthesis of dioxolanes
References
10: Synthesis of isoxazoles, oxazoles, and oxadiazoles
10.1 Introduction
10.2 Synthesis of isoxazoles
10.3 Synthesis of fused isoxazoles
10.4 Synthesis of oxazoles
10.5 Synthesis of fused oxazoles
10.6 Synthesis of oxadiazoles
References
11: Synthesis of thiophenes
11.1 Introduction
11.2 Synthesis of thiophenes
11.3 Synthesis of fused thiophenes
References
12: Synthesis of thiazoles, benzothiazoles, and thiadiazoles
12.1 Introduction
12.2 Synthesis of thiazoles
12.3 Synthesis of benzothiazoles
12.4 Synthesis of fused thiazoles
12.5 Synthesis of thiadiazoles
References
- Edition: 1
- Latest edition
- Published: September 14, 2023
- Language: English
NK
Navjeet Kaur
Dr. Navjeet Kaur, Ph.D. (Chemistry, Banasthali Vidyapith, 2014) is currently an Associate Professor in the Department of Chemistry and Division of Research & Development at Lovely Professional University, Punjab. She specializes in organic synthetic and medicinal chemistry, with a focus on heterocyclic compound synthesis. With 14 years of teaching and research experience, she has guided five Ph.D. scholars and numerous MSc students, and has published over 200 research papers, reviews, books, and chapters. She is the author of nineteen books with leading publishers including CRC Press, Elsevier, and Springer Nature.
Dr. Kaur has consistently ranked among the World’s Top 2% Scientists in subject-wise analyses by Stanford University (2018–2025). She has received awards such as the Prof. G. L. Telesara Award and Best Paper Presentation Award, and has served as Editor-in-Chief of Advanced Chemicobiology Research. Beyond academia, she has contributed to rural development initiatives through NSS and UBA, and holds a Sikh Missionary certification.
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