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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Enhancing Performance for Action and Perception

    Multisensory integration, Neuroplasticity and Neuroprosthetics, Part II
    • 1st Edition
    • Volume 192
    • English
    This volume of Progess in Brain Research follows on from the 32nd International Symposium of the Groupe de recherche sur le système nerveux central (GRSNC), May 2010, and aims to provide an overview of the various neural mechanisms that contribute to learning new motor and sensory skills, and to adapting to changed circumstances, including the use of devices and implants to substitute for lost sensory or motor abilities (brain machine interfaces). The focus is on recent developments covering five major themes: Mechanisms to improve motor performance Neuro-rehabilitation of motor function Mechanisms to enhance sensory perception Cross modal interationc for enhancing sensorimotor performance Assistive technologies to enhance sensorimotor performance This volume focuses on the translation of scientific knowledge into applications and strategies that can help restore lost function following injury or disease including assistive neuroprosthetic technologies to enhance sensorimotor performance and neurorehabilitation.

  • Foundations of Professional Psychology

    The End of Theoretical Orientations and the Emergence of the Biopsychosocial Approach
    • 1st Edition
    • Timothy P. Melchert
    • English
    Recent advances in the scientific understanding of the human mind and brain along with the emphases on evidence-based practice and competency-based education are creating increasing pressures to update some of the traditional approaches to structuring and organizing education and practice in the field. There have also been many calls in recent years for a unified approach to conceptualizing professional practice in psychology. This book examines whether there exists a unified conceptual framework for the field that is firmly based on current scientific understanding regarding human development and functioning, that applies across all the clinical populations and practice areas within the field, and that would also help integrate professional psychology more fully into health care and the sciences generally.

  • Enhancing Performance for Action and Perception

    Multisensory integration, Neuroplasticity and Neuroprosthetics, Part I
    • 1st Edition
    • Volume 191
    • English
    This volume of Progess in Brain Research follows on from the 32nd International Symposium of the Groupe de recherche sur le système nerveux central (GRSNC), May 2010, and aims to provide an overview of the various neural mechanisms that contribute to learning new motor and sensory skills, and to adapting to changed circumstances, including the use of devices and implants to substitute for lost sensory or motor abilities (brain machine interfaces). The focus is on recent developments covering five major themes: Mechanisms to improve motor performance Neuro-rehabilitation of motor function Mechanisms to enhance sensory perception Cross modal interationc for enhancing sensorimotor performance Assistive technologies to enhance sensorimotor performance

  • Neuro-ophthalmology

    • 1st Edition
    • Volume 102
    • Christopher Kennard + 1 more
    • English
    The Handbook of Clinical Neurology Vol 102: Neuro-Ophthalmology provides a comprehensive discussion of the field of neuro-ophthalmology. The book is organized into four sections. Section 1 lays out fundamental concepts of the visual system and eye movements. It discusses the anatomy and physiology of the afferent visual system and the ocular motor system, and the neuro-ophthalmologic... examination. Section 2 deals with disorders of the afferent visual system, covering retinal disorders; abnormalities of the optic disc; lesions of the optic nerve; the optic chiasm; disorders of the optic tract, radiation, and occipital lobe; disorders of higher visual processing; and rehabilitative techniques. Section 3 discusses ocular motor abnormalities, including infranuclear ocular motor disorders; nuclear, internuclear, and supranuclear ocular motor disorders; nystagmus and saccadic intrusions; disorders of higher gaze control; and normal and abnormal lid function. Section 4 covers disorders of the pupil; neuro-ophthalmology of orbital disease; and functional neuro-ophthalmology. This book will be useful to early-stage physicians, as well as specialists interested in the latest developments in neuro-ophthalmology.

  • Translating Mechanisms of Orofacial Neurological Disorder

    From the Peripheral Nervous System to the Cerebral Cortex
    • 1st Edition
    • Volume 97
    • English
    In this volume, members of the International Translational Research Network on Orofacial Neurological Disorders and invited experts provide authoritative overviews of new aspects of motor function and sensation relating to neurological disorders in orofacial regions. Orofacial movements constitute fundamental motor patterns with essential roles in consummatory behavior, self-care, defensive and attack behaviors, vocalization and, in higher mammals, verbal as well as non-verbal communication. Clinically, dysfunction in orofacial movement is evident in numerous dental, cranio-maxillo-facia... and neuropsychiatric disorders, including dysphagia, Huntington's disease, Parkinson's disease and schizophrenia.

  • Space, Time and Number in the Brain

    Searching for the Foundations of Mathematical Thought
    • 1st Edition
    • Stanislas Dehaene + 1 more
    • English
    The study of mathematical cognition and the ways in which the ideas of space, time and number are encoded in brain circuitry has become a fundamental issue for neuroscience. How such encoding differs across cultures and educational level is of further interest in education and neuropsychology. This rapidly expanding field of research is overdue for an interdisciplinary volume such as this, which deals with the neurological and psychological foundations of human numeric capacity. A uniquely integrative work, this volume provides a much needed compilation of primary source material to researchers from basic neuroscience, psychology, developmental science, neuroimaging, neuropsychology and theoretical biology.

  • Muscular Dystrophies

    • 1st Edition
    • Volume 101
    • Robert C. Griggs + 1 more
    • English
    The Handbook of Clinical Neurology Vol 101: Muscular Dystrophies discusses the pathogenesis and treatment prospects for muscular dystrophies. It summarizes the advances in molecular and cell biology, biochemistry, and other biological sciences, with an emphasis on their application to this group of muscle disorders and to their clinical implications. Starting with an overview of muscular dystrophies, the book’s 16 chapters discuss dystrophinopathies; sarcoglycanopathies; congenital muscular dystrophies; collagen VI-related myopathies; limb-girdle muscular dystrophy 2A; dysferlinopathies; limb-girdle muscular dystrophy 2H and the role of TRIM32; and caveolinopathies. The book also covers myofibrillar myopathies; Emery–Dreifuss muscular dystrophy; facioscapulohumeral dystrophy and scapuloperoneal syndromes; oculopharyngeal muscular dystrophy; myotonic dystrophy types 1 and 2; and distal muscular dystrophies. This book is useful to basic investigators, as it offers an increased understanding of muscular dystrophies; and to clinicians, with its emphasis on issues that are relevant to the care, diagnosis, and management of patients with these disorders.

  • Hyperkinetic Movement Disorders

    • 1st Edition
    • Volume 100
    • William J. Weiner + 1 more
    • English
    The Handbook of Clinical Neurology Vol 100: Hyperkinetic Movement Disorders discusses hyperkinetic disorders related mainly to basal ganglia dysfunction and pathology. It contains 13 sections and 51 chapters written by authoritative and experienced investigators and clinicians in this extremely broad and diverse group of diseases and syndromes. The first section on choreoathetoid diseases and syndromes includes chapters on Huntington’s disease and Huntington’s disease look-alikes; spinocerebellar degenerations; neuroacanthocytosis; entatorubral-pallido... atrophy; neuroferritinopathy; neurodegeneration with brain iron accumulation; mitochondrial disorders; acquired hepatocerebral degeneration; benign hereditary chorea; and “senile chorea.” The remaining chapters focus on the abnormal involuntary movements associated with each disease or syndrome. These include immune-related chorea, vascular chorea, metabolic disturbances that can induce chorea, chorea in other medical settings (e.g., postpump chorea in children, cancer-related paraneoplastic syndromes), myoclonus, essential tremor, and dystonia, including dystonia plus syndromes. There are also chapters on tardive dyskinesia, unusual clinical syndromes, and tics and stereotyped movements in children. The text is a valuable resource for neurology and psychiatry residents, practicing neurologists and psychiatrists, and specialists in movement disorders.

  • Human Sleep and Cognition, Part II

    Clinical and Applied Research
    • 1st Edition
    • Volume 190
    • English
    There is a critical, bidirectional relationship between sleep and cognition, yet the literature in this area is scattered, and it is surprisingly difficult to find a comprehensive overview of the basic principles, latest discoveries, and outstanding challenges. This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on the topic in the basic, clinical and applied sciences. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Advances in the Study of Behavior

    • 1st Edition
    • Volume 43
    • English
    Advances in the Study of Behavior was initiated over 40 years ago to serve the increasing number of scientists engaged in the study of animal behavior. That number is still expanding. This volume makes another important "contribution to the development of the field" by presenting theoretical ideas and research to those studying animal behavior and to their colleagues in neighboring fields. Advances in the Study of Behavior is now available online at ScienceDirect full-text online from volume 30 onward.

  • Gene Expression to Neurobiology and Behaviour

    Human Brain Development and Developmental Disorders
    • 1st Edition
    • Volume 189
    • English
    How does the genome, interacting with the multi-faceted environment, translate into the development by which the human brain achieves its astonishing, adaptive array of cognitive and behavioral capacities? Why and how does this process sometimes lead to neurodevelopmental disorders with a major, lifelong personal and social impact? This volume of Progress in Brain Research links findings on the structural development of the human brain, the expression of genes in behavioral and cognitive phenotypes, environmental effects on brain development, and developmental processes in perception, action, attention, cognitive control, social cognition, and language, in an attempt to answer these questions.

  • The Retina and its Disorders

    • 1st Edition
    • Joseph Besharse + 1 more
    • English
    This selection of articles from the Encyclopedia of the Eye covering retina, optics/optic nerve and comparative topics constitutes the first reference for scientists, post docs, and graduate students with an interest beyond standard textbook materials. It covers the full spectrum of research on the retina - from the basic biochemistry of how nerve cells are created to information on neurotransmitters, comparisons of the structure and neuroscience of peripheral vision systems in different species, and all the way through to injury repair and other clinical applications.

  • Essential Neuromodulation

    • 1st Edition
    • Jeffrey Arle + 1 more
    • English
    Neuromodulation is an emerging field that explores the use of electrical, chemical, and mechanical interventions to heal neurological deficits. Such neurostimulation has already shown great promise with disorders and diseases such as chronic pain, epilepsy, and Parkinson’s disease. This is the first concise reference covering all of the basic principles of neuromodulation in a single affordable volume for neuro-residents, fellows, and basic clinical practitioners, edited by two prominent clinical experts in the field. This volume emphasizes essential observations from all of the important clinical phases involved in any neuromodulation: targeting, intraoperative assessment, programming, complications, and complication avoidance. There are commonalities to all neuromodulation procedures that must be brought to the forefront to form a cohesive presentation of neuromodulation, and such emphasis will give readers a more solid grounding in the fundamentals needed to embrace this field as a cohesive clinical entity.

  • La maladie de Parkinson

    • 2nd Edition
    • Luc Defebvre + 1 more
    • French
    La maladie de Parkinson est, après la maladie d'Alzheimer, l'affection neurologique la plus répandue au sein de la population après 50 ans. Elle touche près de 2% des personnes de plus de 65 ans. Ce pourcentage augmentant avec l'âge, on peut prévoir qu'avec le vieillissement de la population, le nombre de patients ne cessera d'augmenter dans les années à venir. Cette deuxième édition rend compte de façon didactique des avancées de ces cinq dernières années, en abordant de façon exhaustive tous les aspects de cette pathologie : l'épidémiologie, l'étiopathogénie, les aspects génétiques, la physiopathologie, les signes moteurs et non moteurs, notamment les troubles cognitifs, psychiques et comportementaux. Sont aussi détaillés les critères diagnostiques, les échelles et questionnaires d'évaluation, la place de l'imagerie morphologique et fonctionnelle ainsi que les stratégies thérapeutiques actuelles : médicamenteuses, chirurgicales, rééducatives et orthophoniques.

  • Ocular Periphery and Disorders

    • 1st Edition
    • Darlene A. Dartt + 5 more
    • English
    This selection of articles from the Encyclopedia of the Eye is the first single-volume overview presenting articles on the function, biology, physiology, and pathology of the structures of the ocular periphery, as well as the related disorders and their treatment. The peripheral structures are implicated in a number of important diseases, including optic neuritis, thyroid eye disease, and strabismus. The volume offers a basic science background of these topics rather than a strictly clinical focus.

  • Animal Behavior / Field and Laboratory Exercises in Animal Behavior (SET)

    • 1st Edition
    • Michael D. Breed + 1 more
    • English
    Animal Behavior/Field and Laboratory Exercises in Animal Behavior (SET) provides a solid background in the neurophysiological and endocrinological bases of animal behavior. This specially priced set includes a copy of Breed and Moore, Animal Behavior and Tillberg/Breed/Hinne... Field and Laboratory Exercises in Animal Behavior. The textbook covers the broad sweep of animal behavior from its neurological underpinnings to the importance of behavior in conservation. Chapters cover behavior and homeostatic mechanisms, behavior and conservation, and behavioral aspects of disease. An entire chapter is devoted to the vibrant new field of behavior and conservation, including topics such as social behavior and the relationship between parasites, pathogens and behavior. Thoughtful coverage is also given to foraging behavior, mating and parenting behavior, anti-predator behavior and learning. Each chapter begins with learning objectives and concludes with thought-provoking questions. Furthermore, special terms and definitions are highlighted throughout. The laboratory manual guides students through the diverse and fascinating fields of behavioral and ethological studies, employing a wide array of organisms as model systems for the study of behavior. Students participate in the development of hypothesis and turn the recording, analysis, and interpretation of data into an active and engaging process. There is also a companion site for faculty and students to enhance their learning experience at: www.elsevierdirect.c... This book will appeal to advanced graduate and undergraduate students in animal behaviour, ethology, and behavioral ecology courses.

  • Pharmacology of 5-HT6 receptors, Part II

    • 1st Edition
    • Volume 96
    • English
    The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized, and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors.

  • The Psychology of Learning and Motivation

    Advances in Research and Theory
    • 1st Edition
    • Volume 54
    • English
    The Psychology of Learning and Motivation series publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Each chapter thoughtfully integrates the writings of leading contributors, who present and discuss significant bodies of research relevant to their discipline. Volume 51 includes chapters on such varied topics as emotion and memory interference, electrophysiology, mathematical cognition, and reader participation in narrative.

  • Breathe, Walk and Chew; The Neural Challenge: Part II

    • 1st Edition
    • Volume 188
    • English
    This volume investigates the implications of how our brain directs our movements on decision-making. An extensive body of knowledge in chapters from international experts is presented as well as integrative group reports discussing new directions for future research. The understanding of how people make decisions is of central interest to experts working in fields such as psychology, economics, movement science, cognitive neuroscience, neuroinformatics, robotics, and sport science. For the first time the current volume provides a multidisciplinary overview of how action and cognition are integrated in the planning of and decisions about action.

  • Development of the Nervous System

    • 3rd Edition
    • Dan H. Sanes + 2 more
    • English
    Development of the Nervous System presents a broad and basic treatment of the established and evolving principles of neural development as exemplified by key experiments and observations from past and recent times. The text is organized ontogenically. It begins with the emergence of the neural primordium and takes a chapter-by-chapter approach in succeeding events in neural development: patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, neuron survival and death, synapse formation and developmental plasticity. Finally, in the last chapter, with the construction phase nearing completion, we examine the emergence of behavior. This new edition reflects the complete modernization of the field that has been achieved through the intensive application of molecular, genetic, and cell biological approaches. It is richly illustrated with color photographs and original drawings. Combined with the clear and concise writing, the illustrations make this a book that is well suited to students approaching this intriguing field for the first time.

  • The Brain as a Drug Target

    • 1st Edition
    • Volume 98
    • Shafiqur Rahman
    • English
    The brain is protected by the blood-brain barrier and this barrier prevents many drugs from entering the brain. This volume discusses various drug delivery and targeting strategies that are being developed to enhance the transport and distribution of drugs into the brain.

  • Learning and Cognition

    • 1st Edition
    • Vibeke Grøver Aukrust
    • English
    This collection of 58 articles from the recently-published third edition of the INTERNATIONAL ENCYCLOPEDIA OF EDUCATION focus on learning, memory, attention, problem solving, concept formation, and language. Learning and cognition is the foundation of cognitive psychology and encompasses many topics including attention, memory, categorization, etc. Most books in the area either focus on one subtopic in-depth (e.g. an entire book on memory) or cover the gamut of subjects in a series of long, technical handbook-like chapters. This concise reference offers researchers and professors teaching in the area a new take on the material that is comprehensive in breadth, but lighter in depth - focusing on main findings, established facts, and minimizing the amount of space taken up by large, multi-volume references.

  • Neuroinflammation

    • 1st Edition
    • Alireza Minagar
    • English
    Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, and brain trauma as well as meningitis and contributes to the generation of pain. We are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage through tolerance to modulation and repair.This book discusses some of the more common neuro-inflammatory diseases. Topics covered include multiple sclerosis, optic neuritis and Susac syndrome.

  • Sleep Disorders Part I

    • 1st Edition
    • Volume 98
    • Pasquale Montagna + 1 more
    • English
    Sleep Disorders Part 1 offers a glimpse of developments that focus on diagnostic techniques in the field of neurobiology of sleep. This part discusses the models of the rapid eye movement (REM) sleep mechanism; issues regarding sleep states, stages, and memory consolidation; and advances in the understanding of the sleep-wake genes, gene products, the circadian clock, and the role of sleep duration. This book explains noninvasive neuroimaging studies, particularly positron emission tomographic and single photon emission computed tomographic scans. It further discusses advances in clinical science, including concepts about neurobiology of sleep, narcolepsy-cataplexy... therapy, and laboratory techniques. The significant advances in therapy have led to the addition of new drugs for the treatment of different sleeping disorders, as described in this book. Sleep is essential to humans. Awareness of its true importance leads to the development and acceptance of sleep medicines in the market.

  • Sleep Disorders Part II

    • 1st Edition
    • Volume 99
    • Pasquale Montagna + 1 more
    • English
    Sleep Disorders II covers various aspects of sleep disorders. These include the different classification of sleep disorders, the genetic influences of sleep disorders, abnormality in the sleeping pattern, and the circadian rhythm sleep disorder. A sleep disorder is a medical disorder that affects the sleeping patterns of humans (and sometimes animals). The disruptions in sleep can be caused by different factors, such as teeth grinding, night terrors, and the like. The book also discusses different perspectives on insomnia and hypersomnia. According to the International Classification of Sleep Disorders, insomnia is a sleep that is low in quality or a difficulty in sleeping. On the other hand, hypersomnia is a sleeping disorder characterized by excessive daytime sleepiness (EDS) or prolonged nighttime sleep. The book discusses narcolepsy, a syndrome that is characterized by excessive daytime sleepiness that is associated with cataplexy and other REM sleep phenomena. The different medicines for this disease are also discussed. People who are practicing neurology and internal medicine, especially those in pulmonary, cardiovascular, gastrointestinal, renal and endocrine specialties, will find this book valuable.

  • Neurological Disorders and Pregnancy

    • 1st Edition
    • Alireza Minagar
    • English
    Timely diagnosis and management of neurological diseases during pregnancy poses major therapeutic challenges to neurologists and other non-neurologist health care providers. Pregnancy is a unique period in life associated with significant hormonal and other physiologic changes in female patients, which may trigger or alter the course of neurological and psychiatric disorders. In addition, many diagnostic procedures that can be performed in non-pregnant women are prohibited during pregnancy for safety reasons. Therapeutic decisions and management of a pregnant patient with neurological disorders heavily depends on the issue of the reasonable balance between the risks of no treatment versus active treatment for the mother and her fetus. This book provides a review of the latest findings in this field, giving the neurologist and non-neurologist the information they need to determine the best treatment. Neurological disorders covered include multiple sclerosis, stroke and epilepsy.

  • Breathe, Walk and Chew

    The Neural Challenge: Part I
    • 1st Edition
    • Volume 187
    • English
    This volume focuses on the interplay of mind and motion-the bidirectional link between thought and action. In particular, it investigates the implications that this coupling has for decision making. How do we anticipate the consequences of choices and how is the brain able to represent these choice options and their potential consequences? How are different options evaluated and how is a preferred option selected and implemented? This volume addresses these questions not only through an extensive body of knowledge consisting of individual chapters by international experts, but also through integrative group reports that pave a runway into the future. The understanding of how people make decisions is of common interest to experts working in fields such as psychology, economics, movement science, cognitive neuroscience, neuroinformatics, robotics, and sport science. So far, however, it has mainly been advanced in isolation within distinct research disciplines; in contrast, this book results from a deliberate assembly of multidisciplinary teams. It offers intense, focused, and genuine interdisciplinary perspective. It conveys state-of-the-art and outlines future research directions on the hot topic of Mind and Motion (or embodied cognition). It includes contributions from psychologists, neuroscientists, movement scientists, economists, and others.

  • Sex Differences in the Human Brain, their Underpinnings and Implications

    • 1st Edition
    • Volume 186
    • English
    This volume of Progress in Brain Research documents recent developments and research findings in relation to sex and how the brain’s function and behavior differs from men to women. Specific areas include cerebral function, morphology and organization, sexual dimorphism, neural origins,and genetics and epigenetics, as well as potential causes/affects of stress, pain, sexual orientation and identity and other social issues such as distribution of disorders across the sexes and autism.

  • Pharmacology of 5-HT6 receptors, Part I

    • 1st Edition
    • Volume 94
    • English
    The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors.

  • Human Sleep and Cognition

    Basic Research
    • 1st Edition
    • Volume 185
    • English

  • Basic Aspects of Catechol-O-Methyltransferase and the Clinical Applications of its Inhibitors

    • 1st Edition
    • Volume 95
    • English
    Volume 95 of International Review of Neurobiology focuses on Catechol-O-methyltra... inhibition, and its clinical application in relation to Parkinson’s disease. Chapters cover COMT gene and proteins, L-dopa treatment in Parkinson’s disease, the latest research on COMT inhibitors and their clinical applications, as well as future prospects for their use.

  • Science of Awakening

    • 1st Edition
    • Volume 93
    • English
    With recent advances of modern medicine more people reach the 'elderly age' around the globe and the number of dementia cases are ever increasing. This book is about various aspects of dementia and provides its readers with a wide range of thought-provoking sub-topics in the field of dementia. The ultimate goal of this monograph is to stimulate other physicians' and neuroscientists' interest to carry out more research projects into pathogenesis of this devastating group of diseases.

  • Developmental Disorders and Interventions

    • 1st Edition
    • Volume 39
    • English
    Volume 39 of the Advances in Child Development and Behavior series is concerned with Developmental Disorders and Interventions. This volume provides an overview of contemporary research into cognitive, neurodevelopmental and genetic disorders of learning. The social, emotional and cognitive functioning of children with William’s syndrome, Down syndrome, Fragile X and autism, reading difficulties, mathematical difficulties and working memory problems are discussed by some of the leading researchers in the field. Within each chapter, the authors consider current interventions and methods for remediating difficulties associated with each disorder, which will be of particular interest to clinical and educational practitioners.

  • MRI Atlas of Human White Matter

    • 2nd Edition
    • Kenichi Oishi + 3 more
    • English
    MRI Atlas of Human White Matter presents an atlas to the human brain on the basis of T 1-weighted imaging and diffusion tensor imaging. A general background on magnetic resonance imaging is provided, as well as the basics of diffusion tensor imaging. An overview of the principles and limitations in using this methodology in fiber tracking is included. This book describes the core white-matter structures, as well as the superficial white matter, the deep gray matter, and the cortex. It also presents a three-dimensional reconstruction and atlas of the brain white-matter tracts. The Montreal Neurological Institute coordinates, which are the most widely used, are adopted in this book as the primary coordinate system. The Talairach coordinate system is used as the secondary coordinate system. Based on magnetic resonance imaging and diffusion tensor imaging, the book offers a full segmentation of 220 white-matter and gray-matter structures with boundaries.

  • Year Book of Neurology and Neurosurgery

    • 1st Edition
    • Volume 2010
    • Alejandro A. Rabinstein
    • English

  • Mouse Behavioral Testing

    How to Use Mice in Behavioral Neuroscience
    • 1st Edition
    • Douglas Wahlsten
    • English
    Mouse Behavioral Testing: How to Use Mice in Behavioral Neuroscience provides detailed explanations of how to conduct an experiment on mouse behavior from the initial planning of the research design through every step of the process until the data analysis phase. The book discusses the practical matters that need to be considered carefully when working with any species of animal, such as how many animals need to be tested. It describes the tests and techniques devised specifically for work with mice. Every step of the research process is illustrated with real situations encountered in previous studies. All examples are based on real experiments, and extensive details of several published experiments are provided. The essential features of a behavioral test protocol are outlined, and several complete protocols are provided. Methods to balance the order of tests and determine throughput are described, then a completely balanced order of tests in a complex experiment is presented. The book will be useful for those already familiar with the general principles of research but are new to the realm of behavioral testing of live mice. It will also serve as a text for a formal course, most likely at the graduate level.

  • Recent Advances in Parkinsons Disease

    Part II: Translational and Clinical Research
    • 1st Edition
    • Volume 184
    • English
    This second volume follows on from Part I by reviewing the variety of animal models of PD current available (from drosophila to rodents to non-human primate species) and their specific contributions to PD research. This is followed by comprehensive coverage of functional neuroimaging studies that explore different pathophysiological questions and evaluate treatment outcome in PD patients. Different areas of experimental therapeutics and outstanding challenges to PD treatment are presented in a concluding group of articles.

  • Dreams and Dreaming

    • 1st Edition
    • Volume 92
    • English
    With recent advances of modern medicine more people reach the 'elderly age' around the globe and the number of dementia cases are ever increasing. This book is about various aspects of dementia and provides its readers with a wide range of thought-provoking sub-topics in the field of dementia. The ultimate goal of this monograph is to stimulate other physicians' and neuroscientists' interest to carry out more research projects into pathogenesis of this devastating group of diseases.

  • Headache

    • 1st Edition
    • Volume 97
    • Giuseppi Nappi + 1 more
    • English
    Handbook of Clinical Neurology: Headache covers various aspects of headaches. It covers up-to-date information about the cultural developments and the scientific advances in the field of neurological science. One of the most frequent symptoms that people encounter is migraine or other type of headaches. At least 40% of neurological consultations are headache-related. With this, significant advances in basic and applied brain sciences have emerged in the field of headache-related problems. Divided into six sections, the book discusses the socioeconomic aspects of headaches, the contribution of biological sciences to the study of the pathophysiology of headache, and the management of headache and other related problems. It also deals with headache-related issues, such as pathogenic (chronobiological, endocrinological, and neuroimaging correlates), nosographic (i.e., migraine, vertigo, and headache in children), and treatment-related issues. The book will serve as a reference for researchers, clinical physicians, and other readers who want additional knowledge about the clinical features of headaches.

  • The Brain

    An Introduction to Functional Neuroanatomy
    • 1st Edition
    • Charles Watson + 2 more
    • English
    The authors of the most cited neuroscience publication, The Rat Brain in Stereotaxic Coordinates, have written this introductory textbook for neuroscience students. The text is clear and concise, and offers an excellent introduction to the essential concepts of neuroscience. Based on contemporary neuroscience research rather than old-style medical school neuroanatomy Thorough treatment of motor and sensory systems A detailed chapter on human cerebral cortex The neuroscience of consciousness, memory, emotion, brain injury, and mental illness A comprehensive chapter on brain development A summary of the techniques of brain research A detailed glossary of neuroscience terms Illustrated with over 130 color photographs and diagrams This book will inspire and inform students of neuroscience. It is designed for beginning students in the health sciences, including psychology, nursing, biology, and medicine.

  • Functional Plasticity and Genetic Variation

    Insights into the Neurobiology of Alcoholism
    • 1st Edition
    • Volume 91
    • English
    With recent advances of modern medicine more people reach the 'elderly age' around the globe and the number of dementia cases are ever increasing. This book is about various aspects of dementia and provides its readers with a wide range of thought-provoking sub-topics in the field of dementia. The ultimate goal of this monograph is to stimulate other physicians' and neuroscientists' interest to carry out more research projects into pathogenesis of this devastating group of diseases.

  • International Review of Research in Mental Retardation

    Health Issues Among Persons with Down Syndrome
    • 1st Edition
    • Volume 39
    • Richard C. Urbano
    • English
    International Review of Research in Developmental Disabilities is an ongoing scholarly look at research into the causes, effects, classification systems, syndromes, etc. of mental retardation. This thematic volume, "Health Issues in Down Syndrome," will cover health issues for individuals across the life span. With the life expectancy of individuals now reaching 60 years or more, it has transformed from an acute condition with a short life span to a chronic condition that needs to be managed over a close to normal life span. The extra chromosome 21 that defines most cases of Down syndrome affects the functioning of many biological processes and organ systems. The cascade of events triggered by the extra chromosome 21 creates a complex set of medical conditions needing to managed over the life span. The ability to manage these conditions has led to an improvement in longevity and quality of life for individuals with Down syndrome.

  • Stress of War, Conflict and Disaster

    • 1st Edition
    • George Fink
    • English
    Stress is a universal phenomenon that impacts adversely on most people. Following on the heels of Stress Science: Neuroendocrinology and Stress Consequences: Mental, Neuropsychological and Socioeconomic, this third derivative volume will provide a readily accessible and affordable compendium that explains the phenomenon of stress as it relates physically and mentally to war, conflict and disaster. The first section will be dedicated to study of the link between stress and various forms of conflict. Specific instances of conflict will be discussed - the Gulf wars, Korea, Hiroshima bombing, the Holocaust, 9/11, Northern Ireland, terrorism in general, torture. The second section will explore the stress impact of more general physical disasters such as airline and vehicle accidents, earthquakes, floods, and hurricanes. The final section will focus on the clinical relationship between conflict stress and various mental diseases – PTSD, suicide, disaster syndrome, etc – as well as the adverse impact of stress on human physical health in general. Comprised of about 100 top articles selected from Elsevier’s Encyclopedias of Stress, the volume will provide a valuable desk reference that will put relevant articles readily at the fingertips of all scientists who consider stress.

  • Signal Processing for Neuroscientists, A Companion Volume

    Advanced Topics, Nonlinear Techniques and Multi-Channel Analysis
    • 1st Edition
    • Wim van Drongelen
    • English
    The popularity of signal processing in neuroscience is increasing, and with the current availability and development of computer hardware and software, it is anticipated that the current growth will continue. Because electrode fabrication has improved and measurement equipment is getting less expensive, electrophysiological measurements with large numbers of channels are now very common. In addition, neuroscience has entered the age of light, and fluorescence measurements are fully integrated into the researcher’s toolkit. Because each image in a movie contains multiple pixels, these measurements are multi-channel by nature. Furthermore, the availability of both generic and specialized software packages for data analysis has altered the neuroscientist’s attitude toward some of the more complex analysis techniques. This book is a companion to the previously published Signal Processing for Neuroscientists: An Introduction to the Analysis of Physiological Signals, which introduced readers to the basic concepts. It discusses several advanced techniques, rediscovers methods to describe nonlinear systems, and examines the analysis of multi-channel recordings.

  • Recent Advances in Parkinsons Disease

    Part I: Basic Research
    • 1st Edition
    • Volume 183
    • English
    This first volume starts with an overview on current perspectives in genetic research and on the molecular mechanisms of neurodegeneration. This is followed by a selection of hot topics in pathophysiological research, from molecular studies to system-level investigations based on in vivo electrophysiological recordings and neurocomputational methods.

  • Transcranial Sonography in Movement Disorders

    • 1st Edition
    • Volume 90
    • English

  • Statistical Signal Processing for Neuroscience and Neurotechnology

    • 1st Edition
    • Karim G. Oweiss
    • English
    This is a uniquely comprehensive reference that summarizes the state of the art of signal processing theory and techniques for solving emerging problems in neuroscience, and which clearly presents new theory, algorithms, software and hardware tools that are specifically tailored to the nature of the neurobiological environment. It gives a broad overview of the basic principles, theories and methods in statistical signal processing for basic and applied neuroscience problems.Written by experts in the field, the book is an ideal reference for researchers working in the field of neural engineering, neural interface, computational neuroscience, neuroinformatics, neuropsychology and neural physiology. By giving a broad overview of the basic principles, theories and methods, it is also an ideal introduction to statistical signal processing in neuroscience.

  • GABAb Receptor Pharmacology: A Tribute to Norman Bowery

    • 1st Edition
    • Volume 58
    • English
    This monograph was assembled to honor Professor Norman Bowery and his work on the 30th anniversary of his discovery of the GABAB receptor. In the present volume, leading neuroscientists from academia and industry provide a perspective of current research, both basic and translational, in the discovery of drugs acting at the GABAB receptor. The topics covered provide a comprehensive review of the field and the current state of research in this area. Included are chapters on the chemistry of GABAB agonists and antagonists, on the genetics and molecular composition of the site, its regulation and trafficking, and its role in controlling cellular, autonomic, and behavioral function. There are also chapters describing the potential clinical utility of drugs regulating GABAB activity receptor in the areas of hypertension, gastroesophageal reflux disease, Down syndrome, depression, and substance abuse. The information contained in this text will be of particular interest to neuroscientists in general and to neuropharmacologists in particular.

  • Treatment of Eating Disorders

    Bridging the Research-practice Gap
    • 1st Edition
    • Margo Maine + 2 more
    • English
    Eating disorders (EDs) affect at least 11 million people in the United States each year and spread across age, race, ethnicity and socio-economic class. While professional literature on the subject has grown a great deal in the past 30 years, it tends to be exclusively research-based and lacking expert clinical commentary on treatment. This volume focuses on just such commentary, with chapters authored by both expert clinicians and researchers. Core issues such as assessment and diagnosis, the correlation between EDs and weight and nutrition, and medical/psychiatric management are discussed, as are the underrepresented issues of treatment differences based on gender and culture, the applications of neuroscience, EDNOS, comorbid psychiatric disorders and the impact of psychiatric medications. This volume uniquely bridges the gap between theoretical findings and actual practice, borrowing a bench-to-bedside approach from medical research.

  • Mathematics for Neuroscientists

    • 1st Edition
    • Fabrizio Gabbiani + 1 more
    • English
    Virtually all scientific problems in neuroscience require mathematical analysis, and all neuroscientists are increasingly required to have a significant understanding of mathematical methods. There is currently no comprehensive, integrated introductory book on the use of mathematics in neuroscience; existing books either concentrate solely on theoretical modeling or discuss mathematical concepts for the treatment of very specific problems. This book fills this need by systematically introducing mathematical and computational tools in precisely the contexts that first established their importance for neuroscience. All mathematical concepts will be introduced from the simple to complex using the most widely used computing environment, Matlab. This book will provide a grounded introduction to the fundamental concepts of mathematics, neuroscience and their combined use, thus providing the reader with a springboard to cutting-edge research topics and fostering a tighter integration of mathematics and neuroscience for future generations of students.

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