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Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering review… Read more
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Chapter One. Inflammation in Anxiety
1 Introduction
2 Cytokines, Brain, and Behavior
3 Inflammation in Anxiety Disorders
4 Inflammation in Anxiety Disorders: Potential Role of Oxidative Stress
5 Oxidative Stress, Transcription Factors, and Inflammation
6 Conclusion
Chapter Two. Inflammation-Related Disorders in the Tryptophan Catabolite Pathway in Depression and Somatization
1 Introduction
2 Tryptophan and the TRYCAT Pathway
3 The TRYCAT Pathway in Somatization
4 Activation of the TRYCAT Pathway May Cause Somatization
5 The TRYCAT Pathway, the CNS, and Somatization
6 Summary
7 Potential Treatment Implications
Chapter Three. Inflammation in Schizophrenia
1 Introduction
2 The Immune Response and the Type-1 and Type-2 Polarization
3 Inflammation in Schizophrenia
4 Type-1 and Type-2 Immune Response in Schizophrenia
5 Antipsychotic Drugs and the Type-1/Type-2 Imbalance in Schizophrenia
6 The Monocyte/Macrophage System in Schizophrenia
7 Brain Imaging and Microglia Activation in Schizophrenia
8 The Tryptophan–Kynurenine Metabolism in Schizophrenia
9 Treatment Options for Schizophrenia Based on Immune Modulation
10 COX-2 Inhibition as Therapeutic Approach in Schizophrenia
Chapter Four. Inflammation in Parkinson’s Disease
1 Introduction
2 Parkinson’s Disease
3 Inflammation in PD
4 Evidence of Inflammation in PD
5 Inflammation in Animal Models of PD
6 Molecular Mechanisms of Inflammation in PD
7 Therapeutic Implications
8 Conclusions
Chapter Five. Treatment with Aβ42 Binding d-Amino Acid Peptides Reduce Amyloid Deposition and Inflammation in APP/PS1 Double Transgenic Mice
1 Introduction
2 Materials and Methods
2.1 Animals
2.2 Peptides
2.3 Hippocampal infusion
2.4 Behavior
2.5 Histopathology
RD