Molecular Biology of Neurodegenerative Diseases
- 1st Edition, Volume 107 - April 13, 2012
- Latest edition
- Editor: David B. Teplow
- Language: English
Neurodegenerative diseases result in progressive degeneration and / or death of nerve cells which leads to problems with movement and mental functioning. Examples include Pa… Read more
Neurodegenerative diseases result in progressive degeneration and / or death of nerve cells which leads to problems with movement and mental functioning. Examples include Parkinson’s, Alzheimer’s and Huntington’s disease. Much research is taking place to try to identify ways to prevent or lessen the impact of these diseases.
This volume reviews the latest research and developments in the molecular biology of neurodegenerative diseases.
- Contributions from leading authorities
- Informs and updates on all the latest developments in the field
Researchers in molecular biology, biochemistry, cell biology and genetics
- Neuropathology and imaging
- Neuropathology and imaging
- Age-dependence of neurodegenerative diseases (organismal genetics)
- AD
- PD
- PD
- Prion I: Human
- Prion II: Yeast
- Cerebral amyloid angiopathy Cerebral amyloid angiopathy
- Membrane Pores
- Unfolded protein response
- ALS
- CAG-repeat diseases
- Mitochondria
Harry Vinters
Thompson, Paul
Tanzi, Rudolph
Dominic Walsh
Guo, Ming
Rochet, Chris and
Surewicz, Witold
Tuite, Mick
Yamada, Masahito Naiki, Hironobu Tau, and Gloria Lee
Kagan, Bruce
Dokholyan, Nikolay
Chris Ross
Lee Martin
- Edition: 1
- Latest edition
- Volume: 107
- Published: April 13, 2012
- Language: English
DT
David B. Teplow
David B. Teplow, Ph.D., is a Professor of Neurology, Emeritus, at UCLA and an internationally recognized leader in efforts to understand and treat Alzheimer's disease. Dr. Teplow's group has used a multi-disciplinary approach to determine how neurotoxic peptides, such as the amyloid β-protein (Alzheimer's disease) and α-synuclein (Parkinson’s disease), form neurotoxic structures that kill neurons and to develop the means to block these processes. Dr. Teplow received undergraduate training at UC Berkeley; a Ph.D. from the University of Washington; and was a postdoctoral scholar at Caltech. Before coming to UCLA, Dr. Teplow was a faculty member in the Department of Neurology, Harvard Medical School. Dr. Teplow has published >250 peer-reviewed articles, books and book chapters, and commentaries, in addition to serving on numerous national and international scientific advisory boards. Dr. Teplow was a founding editor of the Journal of Molecular Neuroscience and Current Chemical Biology, He is Co-Editor-in-Chief of the Elsevier serial Progress in Molecular Biology and Translational Science and is Associate Editor-in-Chief of the American Journal of Neurodegenerative Disease.
Affiliations and expertise
Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, USARead Molecular Biology of Neurodegenerative Diseases on ScienceDirect