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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Dream Science

    Exploring the Forms of Consciousness
    • 1st Edition
    • J. F. Pagel
    • English
    Dreaming is the cognitive state uniquely experienced by humans and integral to our creativity, the survival characteristic that allows for the rapid change and innovation that defines our species and provides the basis for our art, philosophy, science, and humanity. Yet there is little empiric or scientific evidence supporting the generally accepted dream-based theories of neuroconsciousness. Dream Science examines the cognitive science of dreaming and offers an evidence-based view of the phenomenon. Today, such evidence-based breakthroughs in the field of dream science are altering our understanding of consciousness. Different forms of dreaming consciousness occur throughout sleep, and dreamlike states extend into wake. Each dream state is developed on a framework of memories, emotions, representational images, and electrophysiology, amenable to studies utilizing emerging and evolving technology. Dream Science discusses basic insights into the scientific study of dreaming, including the limits to traditional Freudian-based dream theory and the more modern evidence-based science. It also includes coverage of the processes of memory and parasomnias, the sleep-disturbance diagnoses related to dreaming. This comprehensive book is a scientific exploration of the mind-brain interface and a look into the future of dream science.

  • Multiple Sclerosis and Related Disorders

    • 1st Edition
    • Volume 122
    • Douglas S. Goodin
    • English
    Multiple Sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presence of specific genes seem the most probable targets. MS causes an inflammatory response in the central nervous system leading to neurodegeneration, oligodendrocyte death, axonal damage, and gliosis. Over the past five years ongoing research has greatly expanded our understanding of the pathogenesis of MS, detailed insight into the epidemiology and genetic factors related to MS, the introduction of new technologies and tests to better diagnose and predict the future course of the disease and the introduction of new treatments targeting MS. This collection of review chapters provides a comprehensive reference into the science and clinical applications of the latest Multiple Sclerosis research and will be a valuable resource for the neuroscience research community and the clinical neurology community of researchers and practitioners.

  • Molecular Basis of Memory

    • 1st Edition
    • Volume 122
    • English
    This special volume of Progress in Molecular Biology and Translational Science provides a current overview of how memory is processed in the brain. A broad range of topics are presented by leaders in the field, ranging from brain circuitry to synaptic plasticity to the molecular machinery that contributes to the brain's ability to maintain information across time. Memory systems in the prefrontal cortex, hippocampus and amygdala are considered as well. In addition, the volume covers recent contributions to our understanding of memory from in vivo imaging, optogenetic, electrophysiological... biochemical and molecular biological studies.

  • Biomedical Imaging

    Applications and Advances
    • 1st Edition
    • Peter Morris
    • English
    Biomedical Imaging: Applications and Advances discusses the technologies and latest developments in the increasingly important field of imaging techniques for the diagnosis of disease, monitoring of medical implants, and strategies for personalized medicine. Chapters in part one explore the full range of imaging technologies from atomic force microscopy (AFM) to positron emission tomography (PET), as well as the next-generation techniques that could provide the basis for personalized medicine. Part two highlights application-specific biomedical imaging methods, including ophthalmic imaging of ocular circulation, imaging methods for detection of joint degeneration, neural brain activation imaging, and the use of brain imaging to assess post-therapy responses. Further chapters review intravascular, cardiovascular, and whole-body magnetic resonance imaging (MRI). Biomedical Imaging is a technical resource for those concerned with imaging and diagnosis, including materials scientists and engineers as well as clinicians and academics.

  • Principles of Colour and Appearance Measurement

    Object Appearance, Colour Perception and Instrumental Measurement
    • 1st Edition
    • Asim Kumar Roy Choudhury
    • English
    Colour and appearance perceptions are very complex psychological phenomena. Written by one of the foremost authorities in the field, Principles of Colour and Appearance Measurement is a major two-volume work addressing the key topics required to understand the issues and manage colour effectively. The book addresses how objects appear to viewers, how viewers perceive colour, and the major types of instrumentation used to measure colour. Chapters detail the characteristics of light sources and object colour and appearance attributes. They encompass the complexities of human visual perception, including the various causes and types of colour blindness, and other unusual visual phenomena. The book also covers colour measurement instruments and methods, as well as fluorescence and whiteness. Principles of Colour Appearance and Measurement is a comprehensive resource for designers, colour technologists, colour quality inspectors, product developers, and anyone who uses colour in their work.

  • Quantitative MRI of the Spinal Cord

    • 1st Edition
    • Julien Cohen-Adad + 1 more
    • English
    Quantitative MRI of the Spinal Cord is the first book focused on quantitative MRI techniques with specific application to the human spinal cord. This work includes coverage of diffusion-weighted imaging, magnetization transfer imaging, relaxometry, functional MRI, and spectroscopy. Although these methods have been successfully used in the brain for the past 20 years, their application in the spinal cord remains problematic due to important acquisition challenges (such as small cross-sectional size, motion, and susceptibility artifacts). To date, there is no consensus on how to apply these techniques; this book reviews and synthesizes state-of-the-art methods so users can successfully apply them to the spinal cord. Quantitative MRI of the Spinal Cord introduces the theory behind each quantitative technique, reviews each theory’s applications in the human spinal cord and describes its pros and cons, and suggests a simple protocol for applying each quantitative technique to the spinal cord.

  • Neurologic Aspects of Systemic Disease, Part III

    • 1st Edition
    • Volume 121
    • Jose Biller + 1 more
    • English
    Systemic disease involves several parts of the body or the complete system. This comprehensive reference focuses on the specific neurologic aspects of systemic disease. Part 3 includes coverage of oncologic disorders, organ transplantation, infectious diseases, tropical neurology, pregnancy, neuroanesthesia and other diseases and disorders. Each chapter provides a complete introduction to the neurologic aspect and provides the best known diagnostic and treatment practices. The collection will be a valuable and trusted resource for clinical neurologists, research neurologists and neuroscientists and general medical professionals as a first stop for a comprehensive and focused review of the state of the art for understanding the neurologic impact of each covered disease.

  • Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics

    • 1st Edition
    • Carl Faingold + 1 more
    • English
    Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: How the brain carries out important tasks via networks How these networks interact in normal brain function Major mechanisms that control network function The interaction of the normal networks to produce more complex behaviors How brain disorders can result from abnormal interactions How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders.

  • Human Memory

    A Constructivist View
    • 1st Edition
    • Mary B. Howes + 1 more
    • English
    While memory research has recently focused on brain images and neurological underpinnings of transmitters, Human Memory: A Constructivist View assesses how our individual identity affects what we remember, why and how. This book brings memory back to the constructivist questions of how all the experiences of an individual, up to the point of new memory input, help to determine what that person pays attention to, how that information is interpreted, and how all that ultimately affects what goes into memory and how it is stored. This also affects what can be recalled later and what kind of memory distortions are likely to occur. The authors describe constructionist theories of memory, what they predict, how this is borne out in research findings, presenting everyday life examples for better understanding of the material and interest. Intended for memory researchers and graduate level courses, this book is an excellent summary of human memory research from the constructivist perspective.

  • Psychology of Learning and Motivation

    • 1st Edition
    • Volume 60
    • English
    Psychology of Learning and Motivation publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Each chapter thoughtfully integrates the writings of leading contributors, who present and discuss significant bodies of research relevant to their discipline. Volume 60 includes chapters on such varied topics as the balance between mindfulness and mind-wandering; institutions; implications for the nature of memory traces; repetition, spacing, and abstraction; immediate repetition paradigms; stimulus-response compatibility effects; environmental knowledge; and the control of visual attention.

  • Literature, Neurology, and Neuroscience: Neurological and Psychiatric Disorders

    • 1st Edition
    • Volume 206
    • English
    This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume on the neurosciences, neurology, and literature vividly shows how science and the humanities can come together --- and have come together in the past. Its sections provide a new, broad look at these interactions, which have received surprisingly little attention in the past. Experts in the field cover literature as a window to neurological and scientific zeitgeists, theories of brain and mind in literature, famous authors and their suspected neurological disorders, and how neurological disorders and treatments have been described in literature. In addition, a myriad of other topics are covered, including some on famous authors whose important connections to the neurosciences have been overlooked (e.g., Roget, of Thesaurus fame), famous neuroscientists who should also be associated with literature, and some overlooked scientific and medical men who helped others produce great literary works (e,g., Bram Stoker's Dracula). There has not been a volume with this coverage in the past, and the connections it provides should prove fascinating to individuals in science, medicine, history, literature, and various other disciplines.

  • Catecholamine Research in the 21st Century

    Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012
    • 1st Edition
    • Lee E. Eiden
    • English
    Through the use of extended graphical abstracts and some traditional text-only abstracts this collection provides, a record of and roadmap to, the research presented at The Tenth International Catecholamine Symposium (XICS) held in September of 2012. Organized around ten general themes, each is introduced by a short overview identifying interesting research programs, results and potential areas of growth. The collection is a roadmap to key research and future opportunities for new catecholamine research programs and will be of interest to neuroscientists and clinical neurologists interested in understanding the current and future state of catecholamine research.

  • Changing Brains

    Applying Brain Plasticity to Advance and Recover Human Ability
    • 1st Edition
    • Volume 207
    • English
    This volume of Progress in Brain Research focuses on the applying brain plasticity to advance and recover human ability. The volume starts off discussing brain plasticity in the young, adults and old brains with follow on discussions regarding the type of neuroscience-based training that is on offer in impaired child populations as well as discussing the therapeutics involved in adults.

  • Advances in the Neurochemistry and Neuropharmacology of Tourette Syndrome

    • 1st Edition
    • Volume 112
    • English
    This volume of International Review of Neurobiology brings together cutting-edge research on advances in the neurochemistry and neuropharmacology of Tourette syndrome. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and includes important topics regards tics, neurotransmitters, pharmacology and emerging treatments.

  • Neurobiology of Autism

    • 1st Edition
    • Volume 113
    • English
    This volume in the International Review of Neurobiology is a comprehensive overview of the state-of-the-art research into autism pathophysiology. Its chapters cover a wide range of etiologies, from genetics and development to environmental factors. In addition, it discusses key cell and behavioral phenotypes, including cortical and cerebellar phenotypes, as well as language and motor outputs. Finally, this volume's chapters on gene expression in the brain describe how genes may be connected to phenotypes in autism.

  • Literature, Neurology, and Neuroscience: Historical and Literary Connections

    • 1st Edition
    • Volume 205
    • English
    This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume on the neurosciences, neurology, and literature vividly shows how science and the humanities can come together --- and have come together in the past. Its sections provide a new, broad look at these interactions, which have received surprisingly little attention in the past. Experts in the field cover literature as a window to neurological and scientific zeitgeists, theories of brain and mind in literature, famous authors and their suspected neurological disorders, and how neurological disorders and treatments have been described in literature. In addition, a myriad of other topics are covered, including some on famous authors whose important connections to the neurosciences have been overlooked (e.g., Roget, of Thesaurus fame), famous neuroscientists who should also be associated with literature, and some overlooked scientific and medical men who helped others produce great literary works (e,g., Bram Stoker's Dracula). There has not been a volume with this coverage in the past, and the connections it provides should prove fascinating to individuals in science, medicine, history, literature, and various other disciplines.

  • Neural Crest Cells

    Evolution, Development and Disease
    • 1st Edition
    • Paul Trainor
    • English
    Neural Crest Cells: Evolution, Development and Disease summarizes discoveries of historical significance and provides in-depth, current analyses of the evolution of neural crest cells, their contribution to embryo development, and their roles in disease. In addition, prospects for tissue engineering, repair and regeneration are covered, offering a timely synthesis of the current knowledge in neural crest cell research. A comprehensive resource on neural crest cells for researchers studying cell biology, developmental biology, stem cells and neurobiology, Neural Crest Cells: Evolution, Development and Disease provides foundational information needed for students , practicing physicians and dentists treating patients with craniofacial defects.

  • MATLAB for Neuroscientists

    An Introduction to Scientific Computing in MATLAB
    • 2nd Edition
    • Pascal Wallisch + 5 more
    • English
    MATLAB for Neuroscientists serves as the only complete study manual and teaching resource for MATLAB, the globally accepted standard for scientific computing, in the neurosciences and psychology. This unique introduction can be used to learn the entire empirical and experimental process (including stimulus generation, experimental control, data collection, data analysis, modeling, and more), and the 2nd Edition continues to ensure that a wide variety of computational problems can be addressed in a single programming environment. This updated edition features additional material on the creation of visual stimuli, advanced psychophysics, analysis of LFP data, choice probabilities, synchrony, and advanced spectral analysis. Users at a variety of levels—advanced undergraduates, beginning graduate students, and researchers looking to modernize their skills—will learn to design and implement their own analytical tools, and gain the fluency required to meet the computational needs of neuroscience practitioners.

  • Visual Masking

    Studying Perception, Attention, and Consciousness
    • 1st Edition
    • Talis Bachmann + 1 more
    • English
    Visual masking is a technique used in cognitive research to understand pre-conscious processes (priming, for example), consciousness, visual limits, and perception issues associated with psychopathology. This book is a short format review of research using visual masking: how it has been used, and what these experiments have discovered.Topics covered include concepts, varieties, and theories of masking; masking and microgenetic mechanisms and stagesof visual processing; psychopharmacologica... and genetic factors in masking, and more.

  • The Claustrum

    Structural, Functional, and Clinical Neuroscience
    • 1st Edition
    • John R. Smythies + 2 more
    • English
    The present day is witnessing an explosion of our understanding of how the brain works at all levels, in which complexity is piled on complexity, and mechanisms of astonishing elegance are being continually discovered. This process is most developed in the major areas of the brain, such as the cortex, thalamus, and striatum. The Claustrum instead focuses on a small, remote, and, until recently, relatively unknown area of the brain. In recent years, researchers have come to believe that the claustrum is concerned with consciousness, a bold hypothesis supported by the claustrum’s two-way connections with nearly every other region of the brain and its seeming involvement with multisensory integrations—the hallmark of consciousness. The claustrum, previously in a humble position at the back of the stage, might in fact be the conductor of the brain’s orchestra. The Claustrum brings together leading experts on the claustrum from the varied disciplines of neuroscience, providing a state-of-the-art presentation of what is currently known about the claustrum, promising lines of current research (including epigenetics), and projections of new lines of investigation on the horizon.

  • Brain Stimulation

    • 1st Edition
    • Volume 116
    • Andres M. Lozano + 1 more
    • English
    A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world’s most comprehensive source of information in neurology. International list of contributors including the leading workers in the field. Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care.

  • Magnetic Resonance Spectroscopy

    Tools for Neuroscience Research and Emerging Clinical Applications
    • 1st Edition
    • Charlotte Stagg + 1 more
    • English
    Magnetic Resonance Spectroscopy: Tools for Neuroscience Research and Emerging Clinical Applications is the first comprehensive book for non-physicists that addresses the emerging and exciting technique of magnetic resonance spectroscopy. Divided into three sections, this book provides coverage of the key areas of concern for researchers. The first, on how MRS is acquired, provides a comprehensive overview of the techniques, analysis, and pitfalls encountered in MRS; the second, on what can be seen by MRS, provides essential background physiology and biochemistry on the major metabolites studied; the final sections, on why MRS is used, constitutes a detailed guide to the major clinical and scientific uses of MRS, the current state of teh art, and recent innovations. Magnetic Resonance Spectroscopy will become the essential guide for people new to the technique and give those more familiar with MRS a new perspective.

  • Autonomic Nervous System

    • 1st Edition
    • Volume 117
    • Ruud M. Buijs + 1 more
    • English
    Autonomic Nervous System provides an introduction to the latest science and detailed chapters on advances in the clinical diagnosis and treatment of autonomic system disorders. The autonomic nervous system controls all involuntary actions within the human nervous system. Core body functions regulated by the autonomic system include breathing, heartbeat, blood pressure, body temperature, perspiration, and bowel, bladder and sexual function. Our understanding of the neurotransmitters associated with the autonomic nervous system has expanded over the past 15 years associated with current research efforts and are now impacting the diagnosis and treatment of autonomic nervous system disorders by clinical neurologists. This volume is a valuable companion for neuroscience and clinical neurology researchers and practitioners.

  • Neurobiology of Acupuncture

    • 1st Edition
    • Volume 111
    • English
    This book summarises the recent development in acupuncture research and in particular, the neurobiology of acupuncture. It provides a focus but a diverse range of subjects covering many body systems. The first a few chapters discuss the basic principles of acupuncture, then its modulatory effects on nervous system such as induction of neurotrophin and neurogenesis in the brain. Late chapters explore the clinical effects and potential mechanisms of acupuncture on different conditions ranging from neurological diseases such as Parkinson’s, Alzheimer’s, and stroke, to psychiatric illnesses, insomnia, hypertension, gastrointestinal diseases and drug addiction. We believe this will promote the understanding acupuncture treatment and enhance acupuncture research in the future.

  • Metal Related Neurodegenerative Disease

    • 1st Edition
    • Volume 110
    • English
    This issue reviews the role of metals in neurodegenerative diseases; including Parkinson’s and Huntington’s disease; restless leg syndrome and NBIA disorders; and Wilson’s disease and manganese and calcium accumulation disorders. An update on advances in neuroimaging and pathology of metal related disease is also presented.

  • Diffusion MRI

    From Quantitative Measurement to In vivo Neuroanatomy
    • 2nd Edition
    • Heidi Johansen-Berg + 1 more
    • English
    Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie.

  • Endovascular Management of Neurovascular Pathology in Adults and Children, An Issue of Neuroimaging Clinics

    • 1st Edition
    • Volume 23-4
    • Neeraj Chaudhary + 1 more
    • English
    This issue of Neuroimaging Clinics focuses on the endovascular treatment of pathology in adults and children. Topics include cerebral aneurysms, cerebral vasospasms, dural fistulas, carotid stenosis, acute ischemic stroke, vascular malformations, and more.

  • Managing Burnout in the Workplace

    A Guide for Information Professionals
    • 1st Edition
    • Nancy McCormack + 1 more
    • English
    Information professionals are under constant stress. Libraries are ushering in sweeping changes that involve the closing of branches and reference desks, wholesale dumping of print, disappearing space, and employment of non-professional staff to fill what have traditionally been the roles of librarians. Increasing workloads, constant interruptions, ceaseless change, continual downsizing, budget cuts, repetitive work, and the pressures of public services have caused burnout in many information professionals.Managi... Burnout in the Workplace concentrates on the problem of burnout, what it is and how it differs from chronic stress, low morale, and depression. The book addresses burnout from psychological, legal, and human resources perspectives. Chapters also cover how burnout is defined, symptom recognition, managing and overcoming burnout, and how to avoid career derailment while coping with burnout.

  • Neuroanatomy of Language Regions of the Human Brain

    • 1st Edition
    • Michael Petrides
    • English
    Many studies of the neural bases of language processes are now conducted with functional and structural neuroimaging. Research is often compromised because of difficulties in identifying the core structures in the face of the complex morphology of these regions of the brain. Although there are many books on the cognitive aspects of language and also on neurolinguistics and aphasiology, Neuroanatomy of Language Regions of the Human Brain is the first anatomical atlas that focuses on the core regions of the cerebral cortex involved in language processing. This atlas is a richly illustrated guide for scientists interested in the gross morphology of the sulci and gyri of the core language regions, in the cytoarchitecture of the relevant cortical areas, and in the connectivity of these areas. Data from diffusion MRI and resting-state connectivity are integrated iwth critical experimental anatomical data about homologous areas in the macaque monkey to provide the latest information on the connectivity of the language-relevant cortical areas of the brain. Although the anatomical connectivity data from studies on the macaque monkey provide the most detailed information, they are often neglected because of difficulties in interpreting the terminology used and in making the monkey-to-human comparison. This atlas helps investigators interpret this important source of information. Neuroanatomy of Language Regions of the Human Brain will assist investigators of the neural bases of language in increasing the anatomical sophistication of their research adn in evaluating studies of language and the brain.

  • The Rat Brain in Stereotaxic Coordinates

    • 7th Edition
    • George Paxinos + 1 more
    • English
    Since its first edition in 1982, the Paxinos and Watson rat brain atlas has become the most trusted source of accurate coordinates and anatomical information in laboratories throughout the world. It has been cited over 60,000 times, making it the most cited publication in neuroscience. The seventh edition incorporates new findings on developmental gene expression and presents the boundaries of neuromeres in sagittal sections.

  • A Neurological Study of Newborn Infants

    Clinics in Developmental Medicine, No. 28
    • 1st Edition
    • David J. Beintema
    • English
    A Neurological Study of Newborn Infants considers the consistencies and inconsistencies of neonatal neurological signs. The possibility of a relationship between pre- and perinatal complications of pregnancy and later cerebral dysfunction has led to an increasing interest in the early detection of these defects in the newborn infant. This book is divided into nine chapters, and begins with a presentation of standardized procedures to obtain reliable information from the neurological examination. The next chapters deal with the developmental course of neurological signs during the first days of life. The final chapters discuss the potential effects of obstetrical and postnatal conditions on the developmental course and the consistency of neurological signs throughout the neonatal period. This book is an invaluable source for developmental biologists, neurologists, pediatricians, and obstetricians.

  • Cerebral Palsy

    A Clinical and Neuropathological Study
    • 1st Edition
    • Erna Christensen + 1 more
    • English
    Cerebral Palsy: A Clinical and Neuropathological Study is an account of a detailed study in which obstetrical, neonatal and neurological investigations on a large group of patients are presented with full neuropathological data found at subsequent necropsy. The book discusses the general autopsy findings and neuropathological techniques; as well as neuropathological findings in the different clinical entities. The text also describes the neuropathological findings and classification; progressive encephalopathies; and epilepsy. Neurologists will find the book invaluable.

  • Excitation and Inhibition

    Synaptic Morphology
    • 1st Edition
    • Koji Uchizono
    • English
    Excitation and Inhibition: Synaptic Morphology proposes the S-F hypothesis that emphasizes the relationship between structure and function of synapses. This book begins with an introduction to the notion of inhibition in the physiology of the nervous system and history of “synapse”, followed by a discussion on the development of concept and morphological correlates of excitation and inhibition in relation to the S-F hypothesis. The mechanism of synaptic excitation and inhibition, physiological classification of neurons, and release mechanism of transmitters are also elaborated. This text describes the synaptic vesicles as a basis of transmitter, membrane recycle, transmission in the sympathetic ganglion, and transmitter substance. The criticism of S-F hypothesis, which deliberates the skeptical investigations of specialists regarding the simplicity and immaturity of the S-F hypothesis of synaptic morphology are provided at the end. This publication is beneficial to medical students and practitioners aiming to acquire knowledge of the physiology of synapses.

  • The Study of Behavioral Development

    • 1st Edition
    • Joachim F. Wohlwill
    • David S. Palermo
    • English
    The Child Psychology Series: The Study of Behavioral Development concerns the formulation of general laws of development, transcending the realm of the development of the individual from infancy to maturity. This book provides a systematic treatment of problems of research design, strategy, and data analysis that relate specifically to the study of developmental changes in behavior. The topics discussed include developmental psychology in the 1970s, age variable in psychological research, and programmatic view of the task of developmental psychology. The problems of measurement and quantification in developmental psychology, correlational methods in the study of developmental change, and experimental manipulation of developmental change are also elaborated. This publication is recommended for psychologists, specialists, and students learning the nature of behavioral change.

  • Textbook of Neuropathology

    • 2nd Edition
    • Arthur Weil
    • English
    Textbook of Neuropathology, Second Edition covers some of the significant advances in understanding the theoretical and experimental aspects of neuropathology. Neuropathology is the study of the nervous tissue in disease and the determination of deviations of its structures from the normal. This edition is composed of 13 chapters, and begins with the description of the chemical changes occurring in the cell through autolysis and fixation. The subsequent chapters are devoted to studies on better understanding of the vitamin deficiencies, the discovery of the sulfonamides and their contribution to the therapy of meningitis, and the different forms of shock treatment applied to selected cases of neurosis and psychosis. The remaining chapters explore the contribution of neuropathological investigation in various medical conditions, including anemic softening, arteriosclerosis, inflammation, infections, intoxications, injuries, degenerative diseases, tumors, and congenital malformations. This book will be of use to neuropathologists and workers and researchers in the allied fields.

  • The Physiology of Synapses

    • 1st Edition
    • John Carew Eccles
    • English
    The Physiology of Synapses covers the considerable advances in understanding the complex physiology of synapses. This book is divided into 16 chapters that emphasize the mechanism of synaptic transmission. The first chapters describe the structural and physiological features of chemically transmitting synapses. The subsequent chapters deal with the excitatory postsynaptic responses to presynaptic impulse and the release of transmitter by presynaptic impulses. These topics are followed by discussions of the impulse generation by the excitatory postsynaptic potential; the postsynaptic electrical events produced by chemically transmitting inhibitory synapses; the ionic mechanism generating the inhibitory postsynaptic potential. The last chapters consider the mechanism of inhibitory transmitter substances, pathways responsible for postsynaptic inhibitory action, and the trophic and plastic properties of synapses. This book will prove useful to physiologists, neurologists, and researchers.

  • Receptors

    Model Systems and Specific Receptors
    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 11: Receptors: Model Systems and Specific Receptors is a compilation of papers that describes techniques and information that are important to the neurosciences. This volume discusses preferred receptor techniques, molecular techniques, and methods to determine receptor subclasses and localization in the ligand design. The first paper discusses the steroid receptor found in the central nervous system for steroid hormones that affects strongly the structure and function of both developed and immature nervous systems. Another paper describes how a glycoprotein of 79.5 kDa (transferrin) carries iron in the blood stream for delivery to different tissues, after the transferrin has bound with a specific receptor on the surface of the cell. This book also explains the binding sites of pituitary adenylate cyclase-activating polypeptide in the human brain, while one paper analyzes the neurotensin receptors during the primary culture of neurons. This volume then also analyzes the structure and function of the fast nerve growth factor receptor, particularly how a signal on the outside of a cell is transmitted to the cell's interior. This collection is helpful for microbiologists, cellular researchers, students, and professors in the discipline of neurosciences.

  • Neuropeptide Technology

    Synthesis, Assay, Purification, and Processing
    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 6: Neuropeptide Technology: Synthesis, Assay, Purification, and Processing describes procedures and tools of assay useful for the identification, purification, and quantification of neuropeptides and their receptors. This volume is divided into four sections— chemical synthesis and biosynthesis; measurement of neuropeptides; purification and characterization; and neuropeptide degrading and processing enzymes. In these sections, this book specifically discusses the synthesis of peptide substrates for protein kinase C; synthesis of glycosyl neuropeptides; and ultrastructural localization of peptides. The measurement of neurokinin B by radioimmunoassay; purification and characterization of neuroendocrine peptides from rat brain; and preparation of glia maturation factor ß are also elaborated. This text likewise covers the assays for arginine/lysine carboxypeptidases and enzymes that metabolize atrial natriuretic peptide. This publication is beneficial to neuroscientists and students researching on the synthesis, assay, purification, and processing of neuropeptides.

  • Progress in Behavior Modification

    Volume 6
    • 1st Edition
    • Michel Hersen + 2 more
    • English
    Progress in Behavior Modification, Volume 6, is a multidisciplinary serial publication that encompasses the contributions of psychology, psychiatry, social work, speech therapy, education, and rehabilitation. This serial aims to meet the need for a review publication that undertakes to present yearly in-depth evaluations that include a scholarly examination of theoretical underpinnings, a careful survey of research findings, and a comparative analysis of existing techniques and methodologies. The discussions center on a wide spectrum of child and adult disorders. The book opens with a chapter on the various behavioral procedures for treating insomnia. This is followed by separate chapters on behavioral analysis and formulation of the problem of stuttering; the assessment and treatment of enuresis and encopresis in children; and the development of behavior modification in Latin America. Subsequent chapters deal with the analysis of behavior modification from the point of view of its social identity; the conceptual and clinical literature resulting from the broader emphasis in behavior modification; and the relationship between therapist and client.

  • Models of Human Memory

    • 1st Edition
    • Donald A. Norman
    • English
    Models of Human Memory provides an overview of the state of knowledge on human memory models. The book begins with an introductory chapter on the basic stages of the memory system and the historical roots of memory models. The remaining chapters are organized into five parts. Part I on memory systems covers topics such as a system for perception and memory; multi-trace strength theory of memory; and a model for postperceptual verbal memory that postulates a single memory store, with multiple copies, called replicas, created in memory by rehearsal processes. Part II presents studies phoneme storage and word recognition. Part III on memory for associations examines the storage-retrieval theory for the memorizing processes and presents simple model of short-term memory (STM) for paired associates. Part IV on storage and retrieval mechanisms deals with mechanisms of repetition and rehearsal in short-term memory; models of recall and recognition; and memory search models. Part V presents a theory of human long-term associative memory; and examines conceptual and methodological interactions between information-processi... investigations of cognitive activity and attempts to build models of memory.

  • Progress in Behavior Modification

    Volume 4
    • 1st Edition
    • Michel Hersen + 2 more
    • English
    Progress in Behavior Modification, Volume 4, is a multidisciplinary serial publication that encompasses the contributions of psychology, psychiatry, social work, speech therapy, education, and rehabilitation. This serial aims to meet the need for a review publication that undertakes to present yearly in-depth evaluations that include a scholarly examination of theoretical underpinnings, a careful survey of research findings, and a comparative analysis of existing techniques and methodologies. The discussions center on a wide spectrum of child and adult disorders. The present volume opens with a chapter on behavioral treatment for obesity. This is followed by separate chapters on applications of reinforcement techniques in the areas of pollution control and energy conservation, job performance and unemployment, community self-government, racial integration, and others; and behavior modification in community settings. Subsequent chapters deal with demand characteristics in behavior modification; the clinical utility of biofeedback procedures; and the technology of training parents in behavior therapy. The final chapter reviews the rationale and empirical support for the extinction approach of implosive (flooding) therapy.

  • Brain Receptor Methodologies

    Amino Acids. Peptides. Psychoactive Drugs
    • 1st Edition
    • Paul J. Marangos + 2 more
    • English
    Brain Receptor Methodologies: Part B Amino Acids. Peptides. Psychoactive Drugs is the second of the two-part first volume of the Neurobiological Research series, which provides a comprehensive view of various subdisciplines within neurobiology. The first volume (Parts A and B) deals with the area of neurotransmitter and neuromodulator receptors in brain; future volumes will cover the subdisciplines of neuroanatomy, neurophysiology, brain-specific macromolecules, neurochemistry, and behavioral neurobiology. It is hoped that the series will be of equal value for both basic as well as clinical scientists Part B continues from Part A with the remainder of Section II, specific receptor binding methodologies. Subsection II,B deals with receptors for amino acids and neuropeptides and covers areas including GABA, glycine, carnosine, opiates, bombesin, CCK, TRH, and substance P. Amino acids probably represent the majority of brain neurotransmitter substances, at least relative to the amines and acetylcholine, although with the exception of GABA, the amino acids remain relatively uncharacterized in brain. Their further study should receive high priority.

  • Comparative Neuropathology

    • 1st Edition
    • J. R. M. Innes + 1 more
    • English
    Comparative Neuropathology focuses on documented accounts of neurologic diseases and congenital defects in animals. The book first offers information on neuropathology, neuroanatomy, and cerebrospinal fluid (CSF). The domesticated animals that have CSF include horses, dogs, pigs, cats, rabbits, and cattle. The text then elaborates on neurologic diseases of apes and monkeys. Discussions focus on confluent leucoencephalosis and perivascular myelosis, encephalopathies and dysenteric syndromes, meningitis, epilepsies, tuberculosis, cerebellar atrophy and experimental manganese poisoning, and choreic syndrome in baboons with corticostriate encephalitis. The publication examines the diseases of the skeletal muscle and hypophysis, including general reactions of muscles to injuries, congenital defects, muscular dystrophies, changes in muscle associated with specific diseases, and tumor. The manuscript also takes a look at inherited diseases and congenital anomalies, protozoan and bacterial infections, and demyelinating or myelinoclastic diseases. The text is a dependable reference for readers interested in comparative neuropathology.

  • Progress in Behavior Modification

    Volume 5
    • 1st Edition
    • Michel Hersen + 2 more
    • English
    Progress in Behavior Modification, Volume 5, is a multidisciplinary serial publication that encompasses the contributions of psychology, psychiatry, social work, speech therapy, education, and rehabilitation. This serial aims to meet the need for a review publication that undertakes to present yearly in-depth evaluations that include a scholarly examination of theoretical underpinnings, a careful survey of research findings, and a comparative analysis of existing techniques and methodologies. The discussions center on a wide spectrum of child and adult disorders. The book opens with a chapter on the assessment and treatment of minimal dating behavior in college students. This is followed by separate chapters on methods of behavioral control of excessive drinking; behavioral analysis and treatment of child noncompliance to parental requests; and behavioral group therapy. Subsequent chapters deal with the conceptual underpinnings of research in children's self-management and treatment strategies; the assessment and therapeutic functions of self-monitoring; and behavioral treatment in homosexuality.

  • Methods in Neurosciences

    Electrophysiology and Microinjection
    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 4: Electrophysiology and Microinjection is a collection of papers that deals with the electrically excitability feature of many cell types. This volume describes the characteristic features of some nervous tissue to conduct signals along cellular paths or ""wires."" The text presents such paths as a way stimuli are transferred in the nervous system. Section I reviews the recording methodologies such as those used in measuring noninactivating calcium current in smooth muscles cells or the two-suction electrode voltage-clamp recording. Section II deals in detail with voltage clamping and voltammetry; the text also explains the practical steps in using the current pump-assisted voltage clamp. One paper examines the X-ray microprobe analysis of voltage clamped single heart ventricular myocytes, while another paper explains in vivo voltammetry. Section III addresses electrophysiology and purification of specific receptors; one paper presents the results of an electrophysiological study of hormone secretion by single adenohypophyseal cells. Section IV describes special electrodes and equipment, while Section V deals with special preparations needed in culture preparation or in the study of pharmacology of excitatory amino acids on neurons found in the central nervous system. Chapter VI addresses data analysis and reduction such as digital filtering of bioelectric potentials in personal computers. This book will prove valuable for microbiologists, cellular scientists, microchemists, and academicians working in the fields of neuroscience.

  • Principles, Practices, and Positions in Neuropsychiatric Research

    Proceedings of a Conference Held in June 1970 at the Walter Reed Army Institute of Research, Washington, D.C., in Tribute to Dr. David Mckenzie Rioch upon His Retirement as Director of the Neuropsychiatry Division of That Institute
    • 1st Edition
    • Joseph V. Brady + 1 more
    • English
    Principles, Practices and Positions in Neuropsychiatric Research contains the proceedings of a conference held in June 1970 at the Walter Reed Army Institute of Research, Washington, D.C., in tribute to Dr. David McKenzie Rioch upon his retirement as Director of the Neuropsychiatry Division of that institute. This book is composed of the original contributions presented at the conference, as well as several invited papers that could not be programmed at the meeting because of certain limitations. Topics covered in some papers focus on anatomy of the thalamus; glia-neuronal interaction; receptor characteristics and conduction velocities in bladder afferents; responses of photoreceptors; and specificity of responses of cells in the visual cortex. This text also discusses the channeling of responses elicited by hypothalamic stimulation; neurochemistry of reward and punishment; behavioral analysis of aphasia; and biology of sleep. The military psychiatry and changing systems of mental health care, as well as psychological issues in training for research in psychiatry are also addressed. The contributions in this book will serve to reflect the remarkable range of bio-social research interest and competence.

  • Neurobiology and Behavior

    • 1st Edition
    • A. O. Dennis Willows
    • English
    The Mollusca, Volume 8: Neurobiology and Behavior, Part 2, provides an overview of the state of knowledge in molluscan neurobiology and behavior. It is part of a multivolume treatise that covers the areas of structure and function, metabolic biochemistry, molecular biomechanics, environmental biochemistry, physiology, ecology, reproduction and development, neurobiology and behavior, and evolution. The Mollusca is intended to serve a range of disciplines—zoology, biochemistry, physiology, and paleontology. It will prove useful to researchers and to all others with interests in mollusks. The book contains four chapters and begins with a discussion of neural control of cephalopod behavior. Subsequent chapters deal with the neuroanatomy of selected gastropod species; molluscan membranes, gates, and channels; and molluscan transmitters and modulators.

  • Applied Neurophysiology

    With Particular Reference to Anaesthesia
    • 1st Edition
    • J.A. Simpson + 1 more
    • English
    Applied Neurophysiology is intended to promote understanding of the structure and function of the human nervous system for anesthetists. For that reason this book presented concepts rather than critical discussions of experimental work. This book is organized into five parts. There are chapters intended for specialists such as those on vision, control of gaze, hearing and locomotion that were included in order to introduce concepts on brain stem automatisms and cortical function necessary to understand respiration and conscious awareness. There is also a chapter on autonomic nervous system which provides an account of the regulation of the cerebral circulation. The final sections of this volume also include quantitative data and references to original studies which were not thought necessary in other sections. This book will be of interest to anesthetists, clinicians, psychologists, speech pathologists and even neurologists in training.

  • Neurobiology and Behavior

    • 1st Edition
    • A. O. Dennis Willows
    • English
    The Mollusca, Volume 8: Neurobiology and Behavior, Part 1, provides an overview of the state of knowledge in molluscan neurobiology and behavior. It is part of a multivolume treatise that covers the areas of structure and function, metabolic biochemistry, molecular biomechanics, environmental biochemistry, physiology, ecology, reproduction and development, neurobiology and behavior, and evolution. The Mollusca is intended to serve a range of disciplines—zoology, biochemistry, physiology, and paleontology. It will prove useful to researchers and to all others with interests in molluscs. The book contains four chapters and begins with a chapter on the behavior of gastropod mollusks. Subsequent chapters deal with learning in gastropod mollusks, the neuronal control of behavior in gastropods, and the development and plasticity of molluscan neurons.

  • Biochemical Factors Concerned in the Functional Activity of the Nervous System

    First International Meeting of the International Society for Neurochemistry, Strasbourg, 1967
    • 1st Edition
    • D. Richter
    • English
    Biochemical Factors Concerned in the Functional Activity of the Nervous System presents the biological aspects concerned in the functional activity of the nervous system. This book covers several interesting topics concerning the central nervous system, including phospholipids, RNA synthesis, nerve impulse flow, and nerve growth factor. Comprised of 213 chapters, this book begins with an overview of the electron micrographs of calcium–ATP–phosphol... complexes. This text then examines the biochemical and histochemical studies on sectioned rat spinal cords, which demonstrated two types of monoamine-reducing drugs. Other chapters consider the diversity of antagonistic relations between the thiamine derivatives and vitamin B6, which is manifested by changes in the glutamate–GABA, histidine–histamine, tryptophan–serotonin... and tyrosine–noradrenali... systems. This book discusses as well the influence of a conditioned avoidance training experience on the incorporation of radioactive uridine into the RNA of mouse brain. The final chapter deals with the amino acid-incorporating activity of cerebral polyribosomes. This book is a valuable resource for biochemists, neurologists, pharmacologists, and biophysicists.

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