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Systemic disease involves several parts of the body or the complete system. Neurologic Aspects of Systemic Disease, a three-part volume in the Handbook of Clinical Neurology se… Read more
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Systemic disease involves several parts of the body or the complete system. Neurologic Aspects of Systemic Disease, a three-part volume in the Handbook of Clinical Neurology series, focuses on the specific neurologic aspects of systemic disease.
Part 1 includes detailed coverage of cardiovascular disease, pulmonary diseases, renal diseases, and rheumatologic and musculoskeletal disease. Each chapter provides a complete introduction to the neurologic aspect and provides best known diagnostic and treatment practices. The collection is a valuable and trusted resource for clinical neurologists, research neurologists, neuroscientists, and general medical professionals; a first stop for a focused review of the state of the art for understanding the neurologic impact of each covered disease.
Clinical Neurology, Neuroscience
Handbook of Clinical Neurology 3rd Series
Foreword
Preface
Contributors
SECTION 1: Neurologic aspects of cardiovascular disease
Chapter 1: Cardiovascular manifestations of neurologic disease
Abstract
Cardiology in vascular and intensive care neurology
Cardiology of paroxysmal neurologic events
Cardiology of movement disorders and neurodegenerative diseases
Neuromuscular disorders with cardiac manifestations
Conclusion
Chapter 2: Sudden cardiac death
Abstract
Introduction
History
Definition
Pathophysiology and histopathology
Precipitants
Clinical manifestations
Specific clinical scenarios
Potential preventive strategies
Chapter 3: Neurologic complications of cardiac arrest
Abstract
Neurologic complications of cardiac arrest
Epidemiology of cardiac arrest
Treatment of cardiac arrest
Prognosis
Long-term complications of cardiac arrest
Conclusion
Chapter 4: Neurologic complications of cardiac tests and procedures
Abstract
History
Clinical manifestations of neurologic complications of cardiac tests and procedures
Laboratory investigations
Management of acute stroke in the cardiac intensive care unit
Conclusions, future directions
Chapter 5: Neurologic complications of congenital heart disease and its treatment
Abstract
History of congenital heart disease
Incidence of congenital heart disease
Signs and symptoms of congenital heart disease
Cerebrovascular complications of congenital heart disease
Infective embolism from congenital heart disease
Cognitive disturbances with congenital cardiac disease
Brain anomalies with congenital heart disease
Cerebral aneurysm and aortic coarctation
Complications of management
Laboratory investigations
Management
Conclusion
Chapter 6: Neurologic complications of valvular heart disease
Abstract
Introduction
Rheumatic valvular heart disease
Calcific valve disease
Mitral valve prolapse
Prosthetic heart valves
Anticoagulation and its complications
Infective endocarditis
Noninfective endocarditis
Chapter 7: Infective endocarditis
Abstract
Definition
Classification
Historical aspects
Epidemiology
Pathophysiology
Clinical aspects
Diagnosis
Prognosis
Prevention
Treatment
Conclusions
Chapter 8: Neurologic complications of myocardial infarction
Abstract
History
Epidemiology
Risk factors
Etiology
Clinical findings, clinical presentation, and diagnostic criteria
Laboratory investigations
Neuroimaging investigations
Pathology
Management
Prevention
Prognosis
Conclusion and future directions
Chapter 9: Neurologic complications of cardiomyopathies and other myocardial disorders
Abstract
Introduction
Patent foramen ovale
Left ventricular dysfunction
Takotsubo stress cardiomyopathy
Atrial fibrillation
Risk stratification schemes
Bleeding risk: warfarin usage in patients with atrial fibrillation
Genetics
Mitochondrial dysfunction
Summary
Chapter 10: Neurologic complications of arrhythmia treatment
Abstract
Direct neurologic complications of arrhythmia
Neurologic complications of arrhythmia treatment: cardiopulmonary resuscitation
Neurologic complications of arrhythmia treatment: drugs
Neurologic complications of arrhythmia treatment: cardiology procedures
Neurologic complications of arrhythmia treatment: cardiovascular surgery
Conclusion
Chapter 11: Neurologic complications of catheter ablation/defibrillators/pacemakers
Abstract
Introduction
History
Clinical history
Natural history
Laboratory investigations
Neuroimaging investigations
Genetics
Pathology
Management
Neurologic complications associated with pacemakers and defibrillators
Conclusion
Chapter 12: Hypertension and hypertensive encephalopathy
Abstract
History and terminology
Clinical findings
Natural history
Laboratory investigations
Neuroimaging investigations
Genetics
Pathology
Management
Conclusions
Chapter 13: Transient loss of consciousness and syncope
Abstract
Introduction: definitions, nomenclature, and classification
Epidemiology of transient loss of consciousness/syncope
Causes of transient loss of consciousness
Differential diagnosis of transient loss of consciousness
Diagnostic workup of transient loss of consciousness
Treatment of transient loss of consciousness
Acknowledgments
Chapter 14: Neurologic complications of cardiac surgery and interventional cardiology
Abstract
Introduction
History
Clinical findings
Pathology
Natural history
Laboratory and neuroimaging investigations
Management
Conclusions
Chapter 15: Neurologic complications of cardiac tumors
Abstract
Introduction
The clinical triad
Specific cardiac tumors
Diagnosis
Treatment and prognosis
Chapter 16: Neurologic complications of aortic diseases and aortic surgery
Abstract
Introduction
Spinal cord blood supply
Neurologic complications of aortic diseases
Neurologic complications with aortic surgery
Conclusion
SECTION 2: Neurologic aspects of pulmonary diseases
Chapter 17: Breathing and the nervous system
Abstract
Introduction
Neuroanatomy of respiratory control
Physiologic control of breathing and rhythm generation
Neurochemical control of breathing
Neurologic conditions affecting breathing
Clinical manifestations of central and peripheral nervous system conditions
Chapter 18: Obstructive sleep apnea and other sleep-related syndromes
Abstract
Obstructive sleep apnea
Central sleep apnea and hypoventilation syndromes
Acknowledgements
Chapter 19: Acute and chronic respiratory failure
Abstract
Introduction
General approach to diagnosis
Specific diseases
General principles of management in respiratory failure
Management of oropharyngeal and tracheobronchial secretions
Management of respiratory failure in patients with neuromuscular disease
Conclusions
Chapter 20: Venous thromboembolism in neurologic disease
Abstract
Introduction
Epidemiology (with specific focus on neurologic disease)
General principles
Conclusions
Abbreviations
Chapter 21: Neurologic manifestations of sarcoidosis
Abstract
History
Clinical Findings
Clinical Course
Investigations
Epidemiology, Pathophysiology, and Genetics
Pathology
Management
Conclusions
Chapter 22: Neurologic complications of lung cancer
Abstract
Introduction
Lung Cancer Metastases
Paraneoplastic Disorders
SECTION 3: Neurologic aspects of renal diseases
Chapter 23: Neurologic complications of electrolyte disturbances and acid–base balance
Abstract
Introduction
Hyponatremia
Hypernatremia
Hypokalemia
Hyperkalemia
Acid–Base Disorders
Other Electrolytic Disturbances
Chapter 24: Neurologic complications of acute and chronic renal disease
Abstract
Introduction
Central nervous system complications
Central nervous system syndromes associated with renal replacement therapy
Peripheral nervous system disorders
Chapter 25: Nervous system disorders in dialysis patients
Abstract
Introduction
Central nervous system complications
Peripheral nervous system complications
Conclusion
Chapter 26: Nephrotic syndrome
Abstract
Background
Pathophysiology of neurologic sequelae
Neurologic manifestations
Diagnosis, therapy, and prognosis of neurologic aspects
Conclusion
Chapter 27: Use of antiepileptic drugs in hepatic and renal disease
Abstract
Introduction
Individual antiepileptic drugs
Conclusions
SECTION 4: Neurologic aspects of rheumatologic/musculoskeletal diseases
Chapter 28: Neurologic complications of craniovertebral dislocation
Abstract
Introduction
Historical background
Anatomic concepts
Clinical features of craniovertebral subluxation
Neuroimaging
Craniovertebral subluxations associated with neurologic complications
Acknowledgments
Chapter 29: Rheumatoid arthritis, spondyloarthropathies, and relapsing polychondritis
Abstract
Rheumatoid arthritis
Inflammatory spondyloarthropathies
Relapsing polychondritis
Chapter 30: Connective tissue disorders: systemic lupus erythematosus, Sjögren’s syndrome, and scleroderma
Abstract
Introduction
Systemic lupus erythematosus
Scleroderma (systemic sclerosis)
Sjögren's syndrome
Chapter 31: Cerebral vasculitis
Abstract
Introduction and general comments
Cerebral vasculitis of infectious origin
Noninfectious, inlammatory, giant cell, or nectrotizing vasculitis
Chapter 32: Idiopathic inflammatory myopathies
Abstract
History (including classification)
Epidemiology
Etiopathogenesis
Clinical features
Natural history
Laboratory investigations
Neuroimaging investigations
Management
Future therapeutic prospects
Chapter 33: Fibromyalgia
Abstract
History
Clinical findings
Natural history
Laboratory investigations
Neuroimaging investigations
Genetic influences
Pathophysiology
Management
Conclusions
Chapter 34: Paget’s disease of bone
Abstract
History
Clinical findings
Natural history
Laboratory investigations
Neuroimaging investigations
Genetics
Pathology
Management
Conclusions
Chapter 35: Spinal stenosis
Abstract
Definition of spinal stenosis
History
Classification
Epidemiology
Pathophysiology
Diagnosis
Management
Outcome
Conclusions
Chapter 36: Neurologic manifestations of achondroplasia
Abstract
Introduction
Complications associated with achondroplasia
Homozygous achondroplasia
Management of achondroplasia
Acknowledgments
Chapter 37: Neurologic manifestations of inherited disorders of connective tissue
Abstract
Introduction
Neurologic manifestations of the most common inherited disorders of connective tissue
Conclusions
Chapter 38: Nonsteroidal anti-inflammatory drugs exposure and the central nervous system
Abstract
Introduction
Aseptic meningitis
NSAIDs and the risk of stroke
NSAIDs and neuronal degeneration
Medication overuse headache
Reye's syndrome
Other NSAID adverse effects
Overdose and intoxication
Summary
Index
JB
Loyola University Chicago, Maywood, IL, USA
Dr. José Biller is Professor of Neurology and Neurological Surgery and Chairperson of the Department of Neurology at Loyola University Chicago Stritch School of Medicine. Dr. Biller served as Director of the American Board of Psychiatry and Neurology (ABPN) from 1994 to 2001, and President of the ABPN in 2001. He is Chief Editor of the Journal of Stroke and Cerebrovascular Diseases , and an editorial board member and reviewer for an array of other national and international journals and publications. He is a Fellow of the American Academy of Neurology, American Neurological Association, American College of Physicians, and the Stroke Council of the American Heart Association. He has published more than 370 peer-reviewed articles, more than 150 book chapters, and numerous books.
JF