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Elsevier

Books in Life sciences

  • Intelligent Gene Editing in Plants

    The Convergence of AI and CRISPR
    • 1st Edition
    • Aftab Ahmad + 3 more
    • English
    Intelligent Gene Editing in Plants analyzes how AI-enabled design and CRISPR-based genome engineering are reshaping plant genetics, with a clear functional focus on delivering durable gains in crop productivity, stress tolerance, and nutritional quality.The work unfolds in three parts: [i] a foundational survey of genome-editing technologies and the evolving role of AI in precise trait modifications and outcome prediction; [ii] a thorough exploration of applications and synergies, including AI-assisted gRNA optimization, off-target mitigation, regulatory-network analysis, and trait enhancement for disease resistance and climate resilience; and [iii] an emerging-horizons section on cis-regulatory edits, omics integration, synthetic biology, and next-generation editing.Throughout, the volume interweaves practical experiences, cutting-edge methodologies, and case studies, alongside discussions of biosafety, ethical concerns, governance, and public perception, providing a holistic, decision-ready resource for students, researchers, practitioners, and regulatory authorities to navigate the opportunities and responsibilities of plant gene editing, with significant implications for sustainable agriculture and global food security.

  • AI-Driven Cybersecurity for Intelligent Healthcare Systems

    • 1st Edition
    • Balamurugan Balusamy + 3 more
    • English
    AI-Driven Cybersecurity for Intelligent Healthcare Systems explores the intersection between AI, cybersecurity, and healthcare. The book offers detailed insights into the unique cybersecurity challenges faced by the healthcare sector and the role of AI in addressing these challenges. It presents case studies and real-world applications to illustrate the effectiveness of these solutions and highlights the significance of data privacy in healthcare and methods to ensure secure data sharing and storage. Topics such as federated learning, homomorphic encryption, and blockchain technology are covered to demonstrate how AI can enhance data security without compromising patient privacy.This book will be an essential resource for anyone involved in the healthcare industry, offering practical solutions and fostering a more in-depth understanding of how AI can revolutionize cybersecurity in healthcare.

  • Motor Control Methods and Clinical Applications

    • 1st Edition
    • Robert Chen + 1 more
    • English
    Motor Control Methods and Clinical Applications provides a detailed review on the use of non-invasive brain stimulation to study motor control. Split into two distinct parts, this new volume covers the latest research in motor control, including real examples of these methods in a clinical setting. The first part covers advanced methods such as transcranial magnetic, electrical and ultrasound stimulation, long latency, spinal reflexes, multichannel EMG, and EEG-EMG analyses that can be used to examine and modulate the motor system. The second part of the book addresses the clinical applications of these methods.

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 121
    • English
    Advances in Food and Nutrition Research, Volume 121 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Precision nutrition in autoimmune diseases, Current and novel food allergens: cross-reactivity and cross-sensitization risks, Microbiota, fermentation, and metabolite biotransformation: pathways to functional foods and personalized nutrition, Pectins and Modified Pectins: Bridging Food Technology and Human Health Innovations, Methodological Approaches to Assess Protein Digestibility with an Emphasis on Plant-Derived Foods, Recent advances in natural melanin added food packaging, and much more.Additional sections cover A comprehensive overview of the formation of biogenic amines in seafood, Microplastics as an unexplored emerging food contaminant: a challenge for food safety, and Animal-origin food waste hydrolysates for its use as a food/feed ingredient.

  • Protein Kinase Inhibitors

    The Promise of Natural Products in Cancer Therapeutics
    • 1st Edition
    • Md. Imtaiyaz Hassan + 1 more
    • English
    Protein Kinase Inhibitors: The Promise of Natural Products in Cancer Therapeutics explores a novel therapeutic avenue for cancer treatment through nutraceutical-based kinase inhibitors. The book covers their historical background, outlook, mechanistic pathways, and clinical aspects, highlighting their relevance in cancer therapy. It also examines the potential of polyphenolic derivatives and other natural compounds in inhibiting key kinases involved in major cancer signaling pathways, focusing on their application in clinical trials and marketed drugs. Sections explore the implications of polyphenols in cancer management, novel sources of breast cancer inhibitors, the role of natural products in lymphoma therapy, and the multitarget potential of phytochemicals. Each chapter is designed to provide a thorough understanding of how natural products can be harnessed to develop innovative cancer therapeutics. It will serve as a valuable resource for academics, scientists, young researchers, students, and pharmacists working or interested in kinase biology and cancer therapeutics with its unique perspective on using nature's own arsenal to combat cancer.

  • Cardiopulmonary Interactions in Sleep

    Comprehensive Approaches to Mitral Regurgitation and Sleep-Disordered Breathing
    • 1st Edition
    • Kyriakos Dimitriadis + 1 more
    • English
    Cardiopulmonary Interactions in Sleep: Comprehensive Approaches to Mitral Regurgitation and Sleep-Disordered Breathing delves into the correlation between these two serious conditions. Commonly found in patients with cardiovascular disease and heart failure, the interplay between mitral regurgitation and sleep-disordered breathing creates a vicious cycle of clinical deterioration. Their coexistence not only exacerbates disease severity but also increases mortality and adverse cardiovascular outcomes. This book addresses a significant gap in research by exploring this connection and offering insights into diagnosis and treatment.In addition to covering the diagnosis of these conditions, the book discusses coexistent pathologies such as arrhythmias and heart failure. It is the first to focus on the effects of surgical and transcatheter techniques on sleep-disordered breathing. The positive impact of these interventions on sleep respiration and the resulting benefits for mitral valve repair are meticulously analyzed, making it a valuable resource for understanding and treating these interconnected conditions.

  • New Insights in Pediatric Holter Monitoring and Interpretation

    • 1st Edition
    • Gabriel Cismaru + 2 more
    • English
    New Insights in Pediatric Holter Monitoring and Interpretation is the cutting edge book required by pediatric cardiologists and other professionals who encounter arrhythmias in children. Holter ECG examination has recently undergone significant advances in technology, sensors, and software. Yet, these innovations have been considered primarily in the context of adult patients. On the contrary, New Insights in Pediatric Holter Monitoring and Interpretation uses a case-based methodology to illustrate diagnosis and management of actual pediatric patients. Further, it offers guidance in deciding when referrals are necessary for arrhythmological consultations or ablation interventions. This book also contains novel techniques for detecting and interpreting pediatric arrhythmias. These include the introduction of Poincare graphs, Lorenz plots, and other advanced methods for assessing heart rate variability. New Insights in Pediatric Holter Monitoring and Interpretation modernizes readers' understanding of arrhythmias in children, thus improving the young lives of those in their care.

  • Investigative and Predictive Forensic Microbiology

    • 1st Edition
    • Hirak Ranjan Dash
    • English
    Investigative and Predictive Forensic Microbiology showcases the latest advancements in microbial technology for forensic applications, covering a wide range of topics in forensic microbiology. Sections explore human normal microflora, cover classical methods of analyzing microbes, discuss microbial tools in forensic medicine that address post-mortem analysis, and delve into microbial biomarkers for estimating time of death. Investigative microbiology topics include analyzing body fluids, geolocation prediction using microbes, ancient microbial DNA analysis, biodefense, and emerging infections.The book's final section focuses on challenges and future approaches, covering statistical interpretation of data, regulatory considerations, and ethical implications of forensic microbiology. With contributions from renowned experts in the field, this book is a comprehensive resource for researchers and practitioners in microbiology, genetics, forensic science, and for law enforcement professionals and advanced students.

  • Molecular Targets and Therapeutic Design

    • 1st Edition
    • Volume 153
    • English
    Molecular Targets and Therapeutic Design, Volume 152 provides a comprehensive overview of the current landscape and future directions in the identification and exploitation of molecular targets for the development of new therapeutics. This volume brings together leading experts to discuss the fundamental principles of target discovery, validation, and the strategies used to design molecules that modulate biological pathways in disease. Topics covered in this new release include Recent Strategies and Approaches for the Development of Molecularly Targeted Nanomedicine, Transcriptomic Profiling for Therapeutic Target Discovery in Neuropsychiatric Conditions, Transcriptomic Insights into Hormone-Driven Malignancies: Toward Targeted Therapeutic Strategies, and much more.Additional chapters cover Targeting Kinases in Neurodegenerative Diseases and Cancer: Structural Insights and Therapeutic Strategies, Small molecular therapeutic targets for neurodegenerative diseases, Signaling cascades of Tau protein, Understanding molecular role of lipids for Alzheimer's disease, Clinical Challenges and Therapeutic Strategies in Chordoma, Molecular Characterization and Experimental Models of Chordoma, Disordered Proteins as Fuzzy Viral Drug Targets, amongst other timely topics.

  • An Authoritative Guide to Chronic Pediatric Abdominal Pain

    Pathophysiology, Diagnosis and Management
    • 1st Edition
    • Miguel Saps + 1 more
    • English
    An Authoritative Guide to Chronic Pediatric Abdominal Pain: Pathophysiology, Diagnosis and Management provides a comprehensive and extensive overview of all aspects relevant to the care of children with abdominal pain. It includes chapters tailored to each discipline, level of training, and primary interest (clinical or research), covering daily practice, diagnosis, testing, conventional and complementary treatments, interdisciplinary care, and the transition to adult gastroenterology treatment. The book critically updates the evidence behind these methods and prepares readers to understand more advanced techniques. Topics include early adverse life events, intestinal permeability, visceral hypersensitivity, sex differences, microbiome infections, use of antibiotics, and the microbiome.Informati... on clinical perspectives and management in the emergency department helps inform pediatricians, gastroenterologists, residents, fellows, and nurse practitioners about the scientific basis for prior workups, differential diagnoses, and the rationale behind them. In addition, this book helps clinicians understand the basic research behind these factors, how they influence pathophysiology, clinical presentation, progression, and outcomes.

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