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Elsevier

Books in Life sciences

  • Parasitic Protozoa Membranes

    Structure, Singularities and Host-Pathogen Interaction
    • 1st Edition
    • Volume 95
    • English
    Parasitic Protozoa Membranes: Structure, Singularities and Host-Pathogen Interaction, Volume 95 in the Current Topics in Membranes series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Fruit Microbiome

    Emerging Aspects in Postharvest Disease Management
    • 1st Edition
    • Ajay Kumar + 2 more
    • English
    Fruit Microbiome: Emerging Aspects in Postharvest Disease Management covers all areas of microbial ecology and serves as a basis for innovative methods of microbiome engineering and the incorporation of probiotics on fruit nutritional quality. Emphasizing the latest advancements in the fruit microbiome and applications in biocontrol perspectives, the book includes advanced and recent insights into the development of microbial pesticides that will be helpful for those seeking ways to protect and improve plant health and yield protection.Phyto-mic... plays a crucial role in maintaining the health and productivity of all plants, including fruit plants whose yield contributes to global food security. Fruit also harbors numerous microbial communities as an epiphytes or endophytes, and theses microbes play a vital role in protecting them from pathogen invasion during pre-or- postharvest storage. Further, the development and commercialization of several biocontrol products derived from fruits microbiome have proven relevant in broader plant disease management.

  • Hormesis, Brain Aging and Metabolism

    • 1st Edition
    • Volume 295
    • English
    Hormesis, Brain Aging and Metabolism, Volume 295 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Aging and brain metabolism, Calorie restriction: brain physiological and biological aspects, Intermittent fasting and ketone bodies, Physical exercise and brain health: running x sedentary lifestyle, Phytochemicals and brain health, Environmental enrichment and neuroplasticity, Hormesis and brain disease, Neuroinflammation and hormesis, and more.Additional chapters cover Glucocorticoids and Neuroinflammation and Hormesis and cancer.

  • Pharmacoepigenetics

    • 2nd Edition
    • Volume 10
    • Ramón Cacabelos
    • English
    Pharmacoepigenetics, Second Edition, Volume Ten in the Translational Epigenetics series, is a comprehensive reference on the role of epigenetics and epigenomics in drug discovery and development. Here, leading international researchers from across academia, clinical settings, and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the book, chapter authors offer a balanced and objective discussion of the future of pharmacoepigenetics and its crucial contribution to the growth of precision and personalized medicine.This new edition has been fully revised to address recent advances in epigenetics, from new natural and synthetic compounds with epigenetic effects to the role of epigenetics in the pathogenesis of a growing number of complex diseases, including further cancers, cardiovascular disorders, and brain disorders. Newly identified molecular components in the functional architecture of the epigenetic machinery, as well as practical and relevant pharmacoepigenetics topics related to COVID-19 and other world health challenges are also discussed.

  • Therapies for Treatment-Resistant Depression

    Neuropharmacology and Neurostimulation
    • 1st Edition
    • James Murrough + 1 more
    • English
    Therapies for Treatment-Resistant Depression: Neuropharmacology and Neurostimulation provides readers with an authoritative, comprehensive and targeted treatment guide. The first section reviews the essential knowledge and methods of clinical neuroscience and neuropsychopharmacol... techniques as they apply to novel treatment discovery for depression. This is followed by detailed chapters on ketamine, esketamine, other glutamate modulators in development, GABA modulators, neuropeptides, anti-inflammatory agents, and other classes of novel therapeutics under study for TRD and related mood disorders.The last section consists of a set of chapters of special interest that includes current and future research directions, development of psilocybin-based interventions and other psychedelic compounds currently under study for TRD and advances in biomarker-guided and personalized treatment. Edited by world renowned experts in the field, this book is the ultimate resource for researchers and clinicians.

  • Advanced Technologies for Coupled Enhancement of Gas-Solid Separation

    • 1st Edition
    • Chunxi Lu + 1 more
    • English
    Advanced Technologies for Coupled Enhancement of Gas-Solid Separation systematically explains the principles of cyclonic separation, the structural characteristics of equipment, the flow field in the separator, and new concepts and methods of coupled enhancement on cyclonic separation. The book provides basic theories and design methods as well as several new technologies and representative industrial application cases. This reference can be used by scholars, engineers, technicians, and students in the field of oil refining, petrochemical, coal chemical, and pan-chemical manufacturing.

  • The Handbook of Dopamine

    • 1st Edition
    • Volume 32
    • Stephanie J. Cragg + 1 more
    • English
    The Handbook of Dopamine captures current understanding of dopamine biology in the brain, including anatomical organization of dopamine neurons, their molecular and genetic diversity, synaptic and circuit connectivity, receptor function and signalling, through to diverse roles in behaviors and finally, dysfunction in disease. This volume compiles a comprehensive set of perspectives from a large number of leading scientists working in dopamine research. The volume describes the current state-of-the-field, summarizing knowledge that has been transformed in the last decade through the advent and application of sophisticated new technologies.

  • Bleeding Disorders During Pregnancy

    Critical Care Obstetrics
    • 1st Edition
    • Jorge Hidalgo + 2 more
    • English
    Bleeding Disorders During Pregnancy is a volume in the Critical Care Obstetrics series. It is a novel reference to educate physicians, nurses, and all allied healthcare personnel caring for pregnant women with various health compromises that include bleeding. The authors have gathered the best evidence-based material explicitly focused on severe complications in pregnant patients and postpartum. Among the chapters, the book covers medical–surgical complications that any patient can present, such as obstetrics, hemorrhage, hypovolemic shock, and other bleeding complications specific to pregnancy.

  • Neural Interfaces

    • 1st Edition
    • Davide Valeriani + 1 more
    • English
    Neural Interfaces is a comprehensive book on the foundations, major breakthroughs, and most promising future developments of neural interfaces. The book contains the foundational topics of neural technologies, such as what is a brain signal and how to record them. It provides step-by-step tutorials on how to start with small projects and use machine learning to identify specific brain patterns. It also reviews recent advances that promise to guide future developments, including minimally invasive neural technologies. Through a mix of introductory and cutting-edge research, this book is a unique resource to those with an interest in neural interfaces and the latest technologies.

  • Reactive Oxygen Species in Cardiometabolic Syndrome, Neuronal Diseases and Cancer

    From Bench to its Potential Therapeutics
    • 1st Edition
    • Esma R. Isenović + 1 more
    • English
    Reactive Oxygen Species in Cardiometabolic Syndrome, Neuronal Diseases and Cancer: From Bench to its Potential Therapeutics systematically summarizes findings concerning the biochemical properties of various reactive oxygen species (ROS). The book opens with foundational coverage of ROS, ROS signaling, as well as the role of ROS in controlling gene expression. Subsequent chapters cover molecular mechanisms of ROS, regulation of gene expression, and antioxidant supplementation with cardiometabolic syndrome, various neuronal diseases, and cancer. It concludes with recent findings on therapeutic modulations of intracellular levels of ROS, which may significantly impact the development of novel agents for treating the conditions covered.This is a must-have reference for scientists and medical professionals seeking to enhance their knowledge of ROS research and the impact on treatments for cardiometabolic syndrome, neuronal diseases, and cancer.

  • IoT-WSN-DT Based Medical Systems and Nanotechnology for Smart Cancer Care

    • 1st Edition
    • Tuan Anh Nguyen
    • English
    IoT-WSN-DT Based Medical Systems and Nanotechnology for Smart Cancer Care explores the latest advances in nanotechnology, artificial intelligence, Internet of Medical Things (IoMT), digital twin, and wireless sensor networks for real-time cancer care, enabling efficient decision-making and treatment. The book examines how data from medical nanosensors can be integrated with the technology of digital twins for cancer forecasting and monitoring, providing accessible smart insights via remote and mobile devices. By combining the strengths of smart nanotechnology, IoT-based platforms, WSN technologies, and DT, a powerful medical system can be developed for smart cancer care.This system can help in early diagnosis, targeted drug delivery, real-time monitoring, and personalized treatment, ultimately improving patient outcomes.

  • Cardiac Sarcoidosis

    A Multi-discipline Approach
    • 1st Edition
    • Robert Phillip Baughman + 2 more
    • English
    In the past 5 years, there has been a tremendous increase in interest regarding diagnosis and management the cardiac involvement in sarcoidosis. This includes new imaging techniques, new evidence-based guidelines regarding diagnosis and treatment, as well as results of registries providing information regarding the outcome of disease. With this new information, the diagnosis and treatment of cardiac sarcoidosis has become better served. Many centres are now developing multi-disciplinary clinics and conferences to evaluate and treat these patients. These clinics highlight the problem that many different specialities are involved in the care of these patients. A book focusing on the different aspects of the disease will give a reference source for these efforts.Cardiac Sarcoidosis: A Multi-discipline Approach focuses on an important aspect of sarcoidosis: cardiac involvement. From pathology to diagnosis and screening of the disease through treatment options, the book comprehensively reviews known knowledge and explores emerging topics in the field, accompanied by illustrative cases and evidence-based recommendations in outlining the best disease management practices. The book is written by international experts in the field and serves as an essential reference for both clinicians and researchers on cardiac sarcoidosis.

  • Motion Control of Soft Robots

    • 1st Edition
    • Wenyu Liang + 3 more
    • English
    Motion Control of Soft Robots provides an overview of the general concepts and most recent technological updates in soft robot motion control. The book provides systematic coverage of theoretical and practical aspects in system modeling and motion control strategies, presenting novel ideas, methods, and future outlook related to motion control of soft actuators and robots, including model-based control, model-free control, and bioinspired control. This book is useful for researchers, engineers, and students of robotics who can expect to learn how to design and implement various techniques to obtain solutions to control problems in soft robot control and nonlinear system control.

  • Quantum Health AI

    The Revolution of Medicine, Public Health, and Global Health by Quantum Computing-Powered Artificial Intelligence
    • 1st Edition
    • Dominique J. Monlezun
    • English
    Quantum Health AI: The Revolution of Medicine, Public Health, and Global Health is the first comprehensive book defining the transformation of the global health ecosystem by the fusion of our most powerful technologies—quantum computing and artificial intelligence—while defending an actionable human-centred approach to doing so responsibly, equitably, and sustainably. We can continue to watch wars, diseases, poverty, polarization, cyber-crime, and climate change only worsen. Our strongest technologies can remain centralized in a small number of companies and countries for their profit and power. Or we can cooperatively put quantum AI to work for the health of all of us, by better managing this technology’s overarching strategic competition between democracies and autocracies, along with the public and private sectors (balancing human security with national security, economic growth with household livelihoods, individual rights with the common good). This book draws on the decade plus of original research and first-hand perspective of the world’s first triple doctorate-trained physician-data scientist and AI ethicist. It unpacks the history, science, values, and political economics framing and driving quantum AI (including its physics, metaphysics, ethics, governance, computing, sensing, communication, materials, and security), the global health ecosystem (healthcare systems, public health agencies, biotechnology companies, and development institutions), and their growing integration, wins, and challenges. This one-stop book provides a global, inclusive, and practical guide for understanding and shaping these societal and technological trends. It thus empowers health, technology, and policy students, practitioners, professionals, researchers, and leaders in organizations, universities, companies, and governments—ultimate... to make and maintain the human-centred quantum AI safeguarding and advancing humanity’s health, home, and future.

  • Advances in DNA and mRNA-Based strategies for Cancer Immunotherapy: Part B

    • 1st Edition
    • Volume 166
    • English
    Advances in Immunology, Volume 166, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.

  • Thyroid Cancer Update, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 54-3
    • Kenneth Burman + 1 more
    • English
    In this issue of Endocrinology and Metabolism Clinics, guest editors Drs. Jacqueline Jonklaas and Kenneth Burman bring their considerable expertise to the topic of Thyroid Cancer Update. Top experts in the field cover novel treatments, screening strategies, and management, along with topics about survivorship and quality of life.

  • ​Theoretical and Clinical Geropharmacology​

    • 1st Edition
    • Volume 104
    • English
    ​Theoretical and Clinical Geropharmacology​, explores the emerging field of senotherapeutics, which focuses on targeting cellular senescence to reduce age-related diseases and promote healthy aging. Chapters in this new release include Senotherapeutics: Milestones, innovations, and future prospects, Game Changer: Navigating between challenges and hopes in Geropharmacology, Next-Gen Senotherapeutics: AI/ML-driven strategies for aging and age-related disorders, Pharmacological frontiers in senescence: Transforming senescence with drug repurposing, Pharmacological potential of calorie restriction mimetics in mitigating brain aging, Isothiocyanates from cruciferous plants as geroprotectors, and much more.Other chapters cover Cellular parabiosis as a senotherapeutic approach, Molecular imaging for senescent cells-targeted therapeutics in aging and age-related diseases, Mitochondria-associa... membranes (MAMs) in age-related heart diseases, role of endoplasmic reticulum stress, Cellular senescence and senotherapeutics in cardiovascular diseases, Risk of senescence, polypharmacy, and their outcomes in elderly cardiovascular disease patients, Geropharmacology and gastrointestinal surgery, Oxygen-ozone adjunct therapy in aging and senescence-related disorders, and more.

  • Regulated Cell Death in Neurodegenerative Disorders

    • 1st Edition
    • Heba Mohamed Mansour + 1 more
    • English
    Regulated Cell Death in Neurodegenerative Disorders is a comprehensive exploration of the mechanisms and implications of RCD within the realm of neurodegenerative diseases. The book delves into various forms of RCD such as apoptosis, necroptosis, ferroptosis, pyroptosis, and autophagy-mediated cell death, shedding light on their specific roles in disorders like Alzheimer’s, Parkinson’s, Multiple sclerosis, Amyotrophic lateral sclerosis, and Huntington’s. Written by leading experts, each chapter offers unique insights into cellular demise, providing valuable information on treatment options and therapeutic targets. The book features 14 chapters that cover molecular, cellular, and pharmacological mechanisms from an applied science perspective.Topics include the importance of chaperones, kinases, growth factors, inflammaging, mitochondrial dynamics, and oxidative stress. It presents targeted strategies to prevent cell death, reflecting ongoing pursuits in understanding and innovating treatments for neurodegenerative diseases. By offering therapeutic strategies to modulate RCD, this book not only shares knowledge but also provides hope for future advancements in combating these debilitating conditions.

  • Computational Biomechanics of Human Joints

    • 1st Edition
    • Abdelwahed Barkaoui + 2 more
    • English
    Computational Biomechanics of Human Joints delves into the intricate details of each joint, exploring anatomical, mechanical, pathological, and therapeutic aspects. The book offers a comprehensive understanding of joint biomechanics by dedicating each chapter to specific joints, detailing their anatomical structure, biomechanical mechanisms, associated diseases, and pathologies. It also covers treatments, surgical interventions, and imaging-based modeling alongside numerical simulation techniques using the finite element method. This approach provides readers with an innovative perspective on the technological advancements in joint biomechanics. In addition to exploring joint-specific details, the book discusses the advantages and limitations of modern techniques.Finally, the book emphasizes the potential for these methods to improve clinical decision-making, optimize personalized treatments, and design medical devices. The integration of advanced modeling and simulation techniques enhances the understanding of the complex mechanisms of joints, contributing significantly to both academic research and practical clinical applications.

  • Designer Poultry Eggs

    Innovations, Applications, and Future Outlook
    • 1st Edition
    • Arup Giri + 2 more
    • English
    Designer Poultry Eggs: Innovations, Applications, and Future Outlook serves as a comprehensive guide to the science and practical applications of improving egg quality. It explores cutting-edge methods for enriching eggs with omega-3 fatty acids, vitamins, and minerals, while simultaneously reducing cholesterol content. This book is ideal for food scientists, nutritionists, and poultry industry professionals who aim to meet consumer demands, improve egg production, and promote sustainable practices. Beyond nutrient enrichment, the book delves into the use of antioxidants and innovative production strategies to create healthier eggs.It also offers insights into future trends, market applications, and the growing role of designer eggs in addressing global nutritional challenges. With actionable knowledge and strategies, this resource empowers readers to adopt sustainable solutions for enhancing egg quality and overcoming production challenges.

  • Insect Anatomy

    Structure and Function
    • 1st Edition
    • Bernard Moussian
    • English
    Insect Anatomy: Structure and Function provides both morphological and anatomical descriptions of insect tissues and organs and the underlying genetic mechanisms of their function using updated methods. Insects play important roles in diverse ecosystems, with subsequent, tremendous impacts on human society through disease, agriculture effects, and more. Both beneficial and detrimental insect species continuously challenge agriculture and medicine. Written by international experts of insect morphology and anatomy, this book offers concise descriptions of all parts of an insect’s anatomy, including the brain and nervous system, tracheal system, blood, reproductive organs, and kidney system.

  • Advances in Insect Physiology

    • 1st Edition
    • Volume 68
    • English
    Advances in Insect Physiology, Volume 68 in the series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Sections in this new release include The immune and non-immune defenses of aphids, Ecology, Evolution, and Mechanisms of Taste in Social Insects, Neuroendocrine regulation of Malpighian tubules, Tick gut physiology, and Drosophila/insect immunity.

  • Fungal Macromolecule Applications in Life Sciences

    Biological Activity and Medical, Industrial, and Agricultural Applications
    • 1st Edition
    • Jameel R. Al-Obaidi + 2 more
    • English
    Fungal Macromolecule Applications in Life Sciences: Biological Activity and Medical, Industrial, and Agricultural Applications provides a comprehensive guide to the diverse applications of fungal macromolecules, such as proteins, lipid carbohydrates, and nucleic acids. Chapters include an introduction to the background and importance of fungal macromolecules in various life science fields, followed by a detailed overview of the methods for isolating, characterizing, and assessing the structural and functional characteristics of fungal macromolecules.The book discusses the practical applications of fungal macromolecules in the biomedical, agricultural, and industry sectors. It explores potential uses of fungal macromolecules as pharmaceuticals, anti-cancer agents, and inhibitors of bacterial biofilm formation as well as in plant disease management, crop development, enzyme production, biosurfactants, and sustainable and functional food production. The book also examines the antimicrobial properties of fungal macromolecules and their role in managing disease and stimulating human immunology.This comprehensive and multidisciplinary coverage makes Fungal Macromolecule Applications in Life Sciences a valuable resource for scientists, professionals, and advanced students across various fields, including microbiology, biotechnology, biochemistry, pharmacology, agriculture, food science, and biomaterials, looking to enhance their understanding of fungal macromolecules in life sciences and bridge the gap between theory and practical application.

  • Metagenomics for Microbiology

    • 2nd Edition
    • Jacques Izard + 1 more
    • English
    Metagenomics for Microbiology, Second Edition unveils the intricate and diverse world of microbial communities, emphasizing their critical roles in health, disease, and ecosystem functionality. This updated edition addresses the significant challenges in the field and introduces promising approaches to make metagenomics research more feasible. Through comprehensive revisions and over five new chapters, readers are equipped with the latest research data and analyses, advancing their understanding of microbial principles. Notably, this edition provides a robust foundation for the design and analysis of omics studies, focusing on technological underpinnings and practical applications. It remains an essential resource for characterizing microbial consortia.

  • Biosafety Level 4 (BSL4) – Virus research at the highest level of biosafety and biosecurity

    • 1st Edition
    • Volume 122
    • English
    Advances in Virus Research, Volume 122 highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including HERVs in cancer stem cells, Nomenclature for vertical, Modelling of vertically transmitted viruses, Vertical transmission of tomato viruses, and more.

  • Cytokine-Based Immunotherapy - Part A

    • 1st Edition
    • Volume 396
    • English
    Cytokine-Based immunotherapy, Volume 396, Part A delves into the intricate world of cytokines, vital signaling proteins that orchestrate the immune response and their pivotal role in modulating various immune functions. From their fundamental mechanisms to their therapeutic applications, this book offers a thorough examination of the latest trends and developments in leveraging cytokines for immunotherapy. The book includes chapters such as Cytokine-driven cancer immune evasion mechanisms, which explores how cytokines contribute to cancer cells' ability to evade the immune system. Cytokine-based immunotherapy in hematolymphoid malignancies is also explored, discussing the use of cytokines in treating blood cancers.Targeting TNF-alpha examines the immunotherapeutic approach for alleviating neuropathic pain. The key role of immunomodulatory cytokines for the development of novel nk cell-based cancer therapies focuses on the importance of cytokines in developing new cancer treatments. Finally, complexities in the clinical development of TGFβ inhibitors covers the challenges in creating inhibitors for TGFβ.

  • Pain, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 43-3
    • Charles E. Argoff
    • English
    In this issue of Neurologic Clinics, guest editor Dr. Charles E. Argoff brings his considerable expertise to the topic of Pain. Top experts discuss topics related primarily to non-headache pain, including a guide to assessing the person in pain, whether there is a role for acute or chronic opioid therapy; complex pelvic pain and its management; and many more.

  • Formulating and Implementing Pharmaceutical Pricing Policies

    Challenges, Case Studies and Lessons Learned from Medicine Price Control
    • 1st Edition
    • Zaheer-Ud-Din Babar
    • English
    Provides readers with a framework to understand and analyze several medicine pricing policies. Through case studies from countries across geographies and income tiers, this book explores the challenges and opportunities related to price control experiences. Studying global policies this book discusses approaches, strategies, and the underlying pharmaceutical pricing practices used to provide advice for formulating highly effective policies. Alongside the cases, this book covers appropriate research methods for pricing analysis, the essential components of pricing policy, data quality, and the generic structure of a pharmaceutical pricing policy.

  • Biosensing the Future

    Wearable, Ingestible and Implantable Technologies for Health and Wellness Monitoring Part A
    • 1st Edition
    • Volume 215
    • English
    Biosensing the Future: Wearable, Ingestible and Implantable Technologies for Health and Wellness Monitoring, Part A, Volume 215 offers a comprehensive exploration of biosensing technologies and their transformative impact on modern healthcare. Chapters in this new release include Technologies and emerging trends in wearable biosensing, Implantable biosensors: advancements and applications, Neural implants: restoring function and enhancing quality of life, Ingestible biosensors: monitoring health from within, Ingestible biosensors for monitoring digestive health and nutritional monitoring, and much more.Other chapters cover Ingestible biosensors for drug delivery monitoring, Artificial intelligence in wearable biosensing: enhancing data analysis and decision-making, Wearable Privacy, Ethical and regulatory landscape of wearable, ingestible, and implantable technologies, Characterization of skeletal muscle contraction using a flexible and wearable ultrasonic sensor, and more.

  • Immuno-oncology and Immunotherapy Part D

    • 1st Edition
    • Volume 196
    • English
    Immuno-oncology and immunotherapy, Part D, Volume 196 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Investigating the endothelial-immune axis in cancer, Establishing Tyro3, Axl, and Mertk Chinese Hamster Ovary (CHO) Reporter Cell Lines for Cancer Immunology and Therapeutic Applications, Amino acid analog-based labelling of the immunomodulatory cancer secretome, Human and mouse iNKT cell expansion and engineering with viral vectors, Next-generation deconvolution of the tumor microenvironment with omnideconv, and much more.Additional sections cover Comprehensive prediction of tumor neoantigens with NextNEOpi, Ex vivo profiling of organotypic tumor spheroids in 3D microfluidic culture, A flow cytometry-based assay for evaluation of T cell activation and degranulation in coculture systems, An adenosine production assay suitable for 2D and 3D cancer cell culture, Determination of lactate in the tumor interstitial fluid, Combined in vitro differentiation and cell sorting-based isolation of highly pure mouse bone marrow-derived basophils, Organ-on-Chip immunostaining method for three-dimensional identification and study of immune cells responding to drug-treated tumor cells, and much more.

  • The Neuroscience of Feelings: Brain-Heart Connectivity in Neurodegenerative Diseases

    • 1st Edition
    • Volume 294
    • English
    The Neuroscience of Feelings: Brain-Heart Connectivity in Neurodegenerative Diseases, Volume 294 explores the complex interplay between emotions and brain function+G147, covering topics such as The role of heart-brain connectivity in neurodegeneration: mechanisms and impacts, Cardiovascular influence on cognitive decline: the heart's role in neurodegenerative disorders, Autonomic nervous system dysregulation in neurodegenerative diseases: bridging brain and heart, Heart rate variability as an indicator of brain health in neurodegeneration, and much more.Other sections cover Emotional stress and cardiovascular health: impacts on neurodegenerative disease progression, Exploring heart-brain axis alterations in Parkinson’s disease, Cardiac biomarkers as predictors of cognitive decline in neurodegenerative conditions, Heart-brain synchrony: therapeutic implications for neurodegenerative disease, and Neurocardiology and neurodegenerative diseases: emerging research on emotional regulation and brain-heart connectivity.

  • Sustainability in the Manufacturing of Pharmaceuticals

    • 1st Edition
    • Dimitrios A. Lamprou
    • English
    Sustainability in Pharmaceutical Manufacturing is a groundbreaking reference for the pharmaceutical industry. Currently lagging behind other manufacturing sectors, pharmaceutical production requires significant changes in areas such as manufacturing methods, waste management, packaging, and supply chain. This book compiles cutting-edge research from leading global experts, offering scientific insights and innovative strategies to revolutionize sustainability in pharmaceuticals. It explores the transformative potential of the circular economy, lifecycle management, and resource optimization for maximum efficiency and minimal environmental impact.The book delves into green chemistry, highlighting alternative solvents and methods for drug production. It emphasizes novel microfluidic and additive manufacturing techniques, utilizing bio-based sustainable polymers and materials. Chapters on greener drug discovery, development, and scaling processes provide the most current research at each production stage. This invaluable resource enables researchers in academia and industry to make informed choices, enhancing their manufacturing practices and shaping the future of sustainability in the pharmaceutical sector.

  • Primary Brain Tumors in Adults: Advances in Mechanistic Understanding, Evaluation, and Management

    • 1st Edition
    • Volume 166
    • English
    Primary Brain Tumors in Adults: Advances in Mechanistic Understanding, Evaluation, and Management, Volume 166 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Molecular drivers in primary brain tumor formation, Novel CSF pathways in the glioma (DIPG), Volumetric analysis in low grade gliomas and other advanced MR imaging techniques, Liquid biopsy in the diagnosis of primary brain tumors, Intraoperative imaging techniques to improve tumor detection, and much more.Additional chapters focus on Supramaximal resection in primary brain tumors, Radiotherapeutic approaches: IMRT, re-irradiation, Molecularly driven therapies in the treatment of primary brain tumors, and Changes in the immune microenvironment and immunotherapeutic strategies in the treatment of gliomas.

  • Myasthenia Gravis, Part A

    • 1st Edition
    • Volume 182
    • English
    Myasthenia Gravis, Part A, Volume 182 in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as the Structure of the NMJ and Neuromuscular Transmission, Neuromuscular Junction and the Complement System, Regulation of the Autoimmune Response, The Thymus, Antibodies/Subclasse... (IgG) and Antigens, Cell Models of MG, Mouse Models of EAMG and Passive Immunization, Epidemiology of Myasthenia Gravis, Special Populations: Juvenile, Early, Late, and Very Late-Onset, Blood and Digital Biomarkers in MG, Lambert-Eaton Myasthenic Syndrome, and Congenital Myasthenic Syndromes.

  • Neurotoxicity of Solvents

    • 1st Edition
    • Volume 14
    • English
    Neurotoxicity of Solvents, Volume Fourteen highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including the Effect of toluene on memory: A focus on humans, experimental models and treatment approaches, Neurotoxicological Mechanisms of Ethanol, Neurobehavioral Aspects and Methodology of Solvents, Organic solvents and neurodegenerative diseases: exploring a possible link, Neurotoxicity of propylene ethers, An ecotoxicological view on solvents neurotoxicity, and The olfactory system as a target of solvent toxicity.

  • Enfermedad vascular cerebral en jóvenes

    • 1st Edition
    • Fernando Barinagarrementeria Aldatz + 1 more
    • Spanish
    Enfermedad vascular cerebral en jóvenes constituye una contribución inédita en lengua española sobre un tema tan específico como trascendente: la enfermedad vascular cerebral (EVC) en la población joven, escrita por autores internacionales líderes en los diferentes aspectos de este complejo tema. En las últimas décadas, la EVC en jóvenes ha dejado de ser una rareza clínica para convertirse en un problema creciente, con implicaciones significativas por lo que hace a su diagnóstico y manejo. El adecuado abordaje clínico y tecnológico es indispensable para la solución de esta compleja patología, y este título ofrece las herramientas necesarias para su estudio. La presente obra proporciona una revisión exhaustiva de los diferentes aspectos de la enfermedad, abordando su incidencia y factores de riesgo, tanto clásicos como nuevos. También se revisan las diferentes etiologías, y se proporciona un marco para la toma de decisiones clínicas y el manejo de los trastornos cerebrovasculares tanto frecuentes como infrecuentes en esta población.

  • Biotechnology

    The Technological Applications of Genetics and Genomics
    • 3rd Edition
    • David P. Clark + 3 more
    • English
    Biotechnology: The Technological Applications of Genetics and Genomics, Third Edition, approaches modern biotechnology from a molecular basis, discussing how the fields of genetics, molecular biology, microbiology, and biochemistry are merging their respective discoveries into the expanding applied field of biotechnology. Each chapter starts with basic concepts that develop into more specific and detailed applications, providing readers with a good image of possibilities and current limitations in the field and future research directions.This new edition has been fully revised and updated to include research advances, and has new chapters on artificial intelligence, genome editing, precision and personalized medicine, and more. This book is an invaluable resource to anyone interested in understanding what molecular biotechnology is as a scientific discipline, how research in this area is conducted, and how this technology may impact the future.

  • Evapotranspiration in Agro-Ecosystems and Forestry

    Spatio-temporal Applications
    • 1st Edition
    • Suat Irmak
    • English
    Evapotranspiration in Agro-Ecosystems and Forestry: Spatio-temporal Applications presents the progress and advances made in terms of science and application of evaporation, transpiration, and evapotranspiration for various vegetation surfaces, water bodies, and bare soil under different soil and crop management (including different irrigation and tillage management) conditions. Sections on forest and wetlands evapotranspiration and grassland evaporative losses are included, as are the fundamentals of original Penman, Penman-Monteith, Shuttleworth-Wallace and ASCE-EWRI and FAO56 Penman-Monteith equations and their derivatives.The book is an excellent resource to better understand the progression and applications and dynamics of most recent evapotranspiration, evaporation and transpiration measurement and modeling technologies. Case studies will be provided in terms of how different technologies are currently deployed, how data are used for providing information and management decisions to the users.

  • Aedes Aegypti

    Ecology, Population Control, and Vector-borne Disease Prevention
    • 1st Edition
    • B. Vaseeharan + 1 more
    • English
    Aedes aegypti: Ecology, Population Control, and Vector-borne Disease Prevention offers a comprehensive exploration of the Aedes aegypti mosquito, a notorious vector responsible for transmitting diseases such as dengue, Zika, and yellow fever. From its biology and ecological behavior to its microbiota and role in global health crises, the book delves deeply into the intricacies of this species. It stands as a valuable resource for researchers, public health officials, and anyone interested in understanding the challenges posed by this resilient mosquito and the innovative measures employed to mitigate its impact on human health.In addition to extensively discussing the mosquito’s role as a vector, the book emphasizes cutting-edge population control strategies, including genetic modifications, microbial interventions, and community-based efforts. It also addresses the global scale of vector-borne diseases, providing actionable insights into prevention methods, surveillance systems, and the urgent need for interdisciplinary collaboration.

  • Role of Sex and Gender in Aging and Longevity

    • 1st Edition
    • Calogero Caruso
    • English
    Role of Sex and Gender in Aging and Longevity aims to shed light on the complex interplay between sex and gender differences in the aging process and longevity of individuals. While biological sex differences have long been recognized as influencing various aspects of aging, this book includes how gender also plays a significant role in shaping these processes, accelerating aging, or favoring longevity. By acknowledging the influence of both biological and socially constructed factors, this book offers a comprehensive understanding of why individuals may experience different aging trajectories and have divergent longevity outcomes. This book explores the intricate ways in which gender norms, roles, and expectations shape individual experiences of aging and delves into the social determinants of health that can interact with biological factors to influence the aging process and longevity outcomes. By examining these interactions, this book aims to provide a nuanced understanding of the multifaceted nature of aging and longevity and how sex and gender contribute to these complex phenomena, laying the groundwork for future aging research and providing significant implications for disease prevention, screening, diagnosis, and treatment of age-related conditions.

  • Harmful Algal Blooms

    Environmental Factors and Molecular Mechanisms
    • 1st Edition
    • Senjie Lin
    • English
    Harmful Algal Blooms: Environmental Factors and Molecular Mechanisms offers a genomic and ecological perspective on harmful algal blooms, or HABs. The book provides the most updated and comprehensive knowledge crucial for understanding the causes of HABs while also synthesizing foundational knowledge with recent discoveries. Written by an expert in algal molecular ecology, it blends molecular biology, physiology, and ecology to examine how harmful algae thrive on environmental conditions like climate change. After introducing historical ecological models, the book delves into the influencing factors and underlying molecular mechanisms of HABs.Other sections explore an integrated molecular approach to incorporate energy, nutrients, defenses, and sexual reproduction (ENDs) as a resolution for HAB growth. This is an important resource for researchers and students in marine biology and ecology fields, as well as phycological and environmental studies.

  • The Microbiome in Cancer and Autoimmunity - Part B

    • 1st Edition
    • Volume 395
    • English
    Microbiome in Cancer and Autoimmunity - Part B, Volume 395 offers a comprehensive exploration of the intricate relationship between the human microbiome and the development of cancer and autoimmune diseases. Delving into cutting-edge research and clinical insights, this groundbreaking work elucidates the role of microbial communities in influencing immune responses, disease pathways, and therapeutic outcomes. Specific chapters cover the Effect of Microbial Dysbiosis on Autoimmune-Associate... Inflammation, Gut Microbiota and Systemic Immune Responses in Cancer, The role of microbiome in gastrointestinal cancer, Cancer and Microbiome-Targeted Therapies, Autoimmune disease and Microbiome Targeted Therapies, and the Effect of Diet and Lifestyle on Microbiome Composition.

  • Genomics-Guided Natural Products Discovery

    • 1st Edition
    • Volume 717
    • English
    Genomics-Guided Natural Products Discovery, Volume 717 focuses on how the genomics revolution has catalyzed a resurgence of interest in natural products research. With the explosion of new sequencing data to analyze, “genome-mining” tools have grown in sophistication. Hence, this volume captures the utility of these tools, serving as a how-to guide to lower the entry barrier for newcomers. Topics covered in this new release include Merging RODEO with genomic enzymology workflows to guide RiPP discovery, Exploring Ribosomally Synthesized and Post-translationally Modified Peptides through SPECO-Based Genome Mining, Genome Mining for Natural Products Made by Multinuclear Iron-dependent Oxidation Enzymes (MNIOs), and much more.Additional sections explore Genome-based discovery of polyketides generated by trans-acyltransferas... polyketide synthases, Global genome mining in fungi using FunBGCe, Plant genome mining of burpitides from fused precursor peptides, Determining biosynthetic gene cluster boundaries thru comparative bioinformatics, Genome mining for bacterial terpenoids, Bioinformatics guided synthesis of natural product cyclic peptides, Overview of Genome Mining Strategies for Natural Products Discovery, and much more.

  • Management and Treatment of Cerebral Aneurysms, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 35-3
    • Daniel Sahlein + 1 more
    • English
    In this issue of Neuroimaging Clinics, guest editors Drs. Daniel Sahlein and Charles Kulwin bring their considerable expertise to the topic of Management and Treatment of Cerebral Aneurysms. Top experts discuss diagnostic and clinical aspects of cerebral aneurysms, as well as epidemiology, unruptured cerebral aneurysms, predicting cerebral aneurysm rupture, subarachnoid hemorrhage, and follow-up imaging in treated and untreated cerebral aneurysms.

  • Environmental Pollution and Cardiovascular Diseases

    • 1st Edition
    • Sultan Ayoub Meo
    • English
    Environmental Pollution and Cardiovascular Diseases helps stakeholders enhance their knowledge about environmental pollution, weather conditions, climate change, and impacts on the cardiovascular system. The book further aims to ameliorate the global burden of cardiovascular deaths attributable to pollution by identifying trends in pollution-linked cardiovascular disease from the 1990s to present day. Overall, air pollution is estimated to cause about 34% of ischemic heart disease deaths. As these figures show no sign of declining, this book is a must-have for researchers, cardiologists, and others seeking to understand such an important etiological factor in so many cardiovascular illnesses.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 127
    • English
    Advances in Clinical Chemistry, Volume 127 explores physiologic and pathophysiologic biochemistry in both general and clinical chemistry. Complex molecular pathways are elucidated using historical, current, and emerging technologies such as biosensor design, metabolomics, and proteomics. Chapters in this new release include The Cancer Microbiome, Metabolomics of Nephrotic Syndrome, Advances in Biomimetic Sensor Technology, Gel electrophoresis-base... proteoform separation and analysis, Advances in blood microsampling technology for cancer biomarker detection, and MDDB: A public databank of host microRNAs in Tuberculosis diagnosis.

  • Autoimmune Hemolytic Anemias

    A Practical Guide
    • 1st Edition
    • Wilma Barcellini + 1 more
    • English
    Autoimmune Hemolytic Anemias: A Practical Guide is a comprehensive update of autoimmune hemolytic anemias, a rare disease that is sometimes difficult to diagnose and manage. This book describes diagnosis, pathogenesis, classification, standard therapy, new treatments, as well as secondary forms, such as lymphoproliferative, immunodeficiency, Evans, and other autoimmune diseases. It is a practical guide to manage transfusions and monitoring complications, such as infections and thromboses, and preventive measures. This book is useful to researchers, clinicians, doctors and students working in hematology, transfusion centers, immunohematology labs, and internal medicine.

  • Cryo-electron Tomography

    A Journey From Sample Preparation to Data Mining
    • 1st Edition
    • Dorit Hanein + 1 more
    • English
    Cryo-Electron Tomography: A Journey from Sample Preparation to Data Mining providing a holistic overview of this rapidly advancing field and equipping researchers with the knowledge and tools necessary to initiate their own investigations. The book begins with a section on advanced cryogenic sample preparation for in situ cellular tomography, covering a range of sample types including viruses, bacteria, eukaryotic cells, and perspectives for organoids and tissues. Specific chapters focus on essential approaches such as vitrification, sample thinning, and bimodal correlative techniques. The book then transitions to a section on data mining and validation.

  • Narcolepsy

    Integrating Basic and Clinical Knowledge
    • 1st Edition
    • Ahmed S. BaHammam + 2 more
    • English
    Narcolepsy: Integrating Basic and Clinical Knowledge provides comprehensive coverage of narcolepsy-related topics. The book offers updated, deep coverage of its diagnosis, treatment, and impact on mental health based on the latest research findings and clinical practices. Its interdisciplinary approach brings together experts from different specialties, such as sleep medicine, psychology, and neurology to offer a more holistic understanding. This allows for a more nuanced discussion of how narcolepsy interacts with various aspects of health and well-being. Researchers and clinicians will find within this book novel information on pathophysiology and neurobiology, as well as behavioral and psychosocial considerations.Users will find this to be a resource that takes a deep dive into narcolepsy, introducing topics never before discussed in books on the topic, including COVID-19 and sleep, as well as immunotherapy and gene therapy. It’s the cutting-edge medical volume professionals need, whether narcolepsy specialists or more casual readers.

  • Handbook of Proteolytic Enzymes

    Metallopeptidases
    • 4th Edition
    • Neil D. Rawlings + 1 more
    • English
    Handbook of Proteolytic Enzymes, Metallopeptidases has stood as most comprehensive work in the field of applied enzymology and biocatalysis since the first edition published in 1998. Extensively revised and updated, the new fourth edition is an essential reference for biochemists, biotechnologists, and molecular biologists across academia and industry. Edited by world-renowned experts in the field, and with five volumes available for individual sale, this work provides detailed information on all known proteolytic enzymes researched to-date, with expanded coverage of metallopeptidases, cysteine peptidases, serine and threonine peptidases, aspartic and glutamic peptidases, and inhibitors of proteolytic enzymes.This volume includes over 300 chapters on known metallopeptidases enzymes, including their name, history, activity and specificity, structural chemistry, preparation, biological aspects, and distinguishing features, with 2D structures of peptidases in color, extensive references, and links to PubMed and MEROPS databases.

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