Technological Advances and Innovations in the Treatment of Chronic Respiratory Disorders

1st Edition - November 21, 2024
Editors: Gabriele De Rubis, Divya Suares, Kamal Dua, Ronan MacLoughlin, Hélder A. Santos, Saritha Shetty
Language: English
Paperback ISBN:
9 7 8 - 0 - 4 4 3 - 2 7 3 4 5 - 2
eBook ISBN:
9 7 8 - 0 - 4 4 3 - 2 7 3 4 4 - 5

Technological Advances and Innovations in the Treatment of Chronic Respiratory Disorders provides a comprehensive overview of the latest therapeutic and diagnostic innova… Read more

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Technological Advances and Innovations in the Treatment of Chronic Respiratory Disorders provides a comprehensive overview of the latest therapeutic and diagnostic innovations in the field, with a focus on 3D printing, bioprinting, microfluidics, organ-on-a-chip systems, and molecular modelling. The book, written by a team of leading experts in the field, is an essential resource for anyone who is interested in the future of CRD treatment. It begins by providing an overview of the economic and healthcare burden of CRDs, as well as the current treatment strategies available. The next chapters discuss the emerging therapeutic approaches for CRDs, including biologicals and phytoceuticals. The core chapters of the book then cover the application of 3D printing, bioprinting, microfluidics, organ-on-a-chip systems, and molecular modelling to the different CRDs. The book concludes with a discussion of the current clinical trials and future prospects for the management of CRDs. Technological Advances and Innovations in the Treatment of Chronic Respiratory Disorder is a valuable resource for researchers, clinicians, and other healthcare professionals who are interested in the latest technological advances in the field of CRDs. It will also be of interest to students and scientists who are working in the fields of pharmaceutical sciences, microfluidics, bioinformatics, drug design, drug delivery, and 3D printing.

Gabriele De Rubis

Gabriele holds a Bachelor's Degree in Biotechnology ("La Sapienza" University of Rome, Italy) and a Master's degree in Genetic Sciences and Technologies (University of Sannio, Benevento, Italy). He has just completed a PhD in Pharmacy (thesis under examination) at the Discipline of Pharmacy, Graduate School of Health, UTS, with a thesis on the development of advanced drug delivery systems for respiratory diseases. Gabriele has extensive experience as an industry-based researcher, particularly in the setup and evaluation of animal (mouse and rat) models of cancer and inflammatory diseases and in the preclinical in vivo testing of the safety, efficacy and pharmacokinetic properties of novel anti-cancer and anti-inflammatory drugs. Gabriele's current expertise and research interest cover the in vitro advanced drug delivery of phytoceuticals and nucleic acid-based therapeutics (decoy oligodeoxynucleotides, miRNAs) for the treatment of respiratory inflammatory diseases and lung cancer.

Affiliations and expertise

University of Technology Sydney, Australia

Divya Suares

Dr. Divya Suares Assistant Professor, Pharmaceutics Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM's NMIMS, V.L. Mehta Road has a search experience of over 14 years in the area of drug delivery. Dr. Divya completed her Bachelor’s Degree in Pharmacy and Master’s Degree in Pharmaceutics from Rajiv Gandhi University of Health Sciences, India. She completed her Doctor of Philosophy in Pharmaceutical Sciences from NMIMS deemed-to-be University, wherein her research project involved development and evaluation of lipid based formulation of Rosuvastatin. Dr. Divya’s research interest encompass the development of drug delivery systems via the oral, topical, intranasal route for the management of various disorders, development of effective formulations for wound healing and pediatric-friendly drug delivery systems. Edit

Affiliations and expertise

Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, India

Kamal Dua

Dr. Kamal Dua is a Senior Lecturer in the Discipline of Pharmacy at the Graduate School of Health, University of Technology Sydney (UTS), Australia. He has research experience of over many years in the field of drug delivery systems targeting inflammatory diseases. Dr. Dua researches in two complementary areas; drug delivery and immunology, specifically addressing how these disciplines can advance one another, helping the community to live longer and healthier. This is evidenced by his extensive publication record in reputed journals. Dr. Dua’s research interests focus on harnessing the pharmaceutical potential of modulating critical regulators such as Interleukins and microRNAs and developing new and effective drug delivery formulations for the management of chronic airway diseases. He has published more than 80 research articles in peer-reviewed international journals and authored or co-authored four books. He is an active member of many national and international professional societies.

Affiliations and expertise

Senior Lecturer, Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, NSW, Australia

Ronan MacLoughlin

Dr Ronan MacLoughlin is Director R&D, Science & Emerging Technologies, at Aerogen, an Irish medical device company specialising in Respiratory Drug Delivery. He is a former head of Medical Affairs, with responsibility for >45 investigator-initiated trials. With more than 20 years’ experience in the design and development of drug delivery systems and drug device combinations, he has >220 collaborative publications, as well as 12 granted patents. His most recent focus has been on enabling several clinical programs making use of aerosolised prophylactics and therapeutics for COVID-19, and his work on delivery of inhaled vaccines has resulted in the world’s first approval for an orally inhaled vaccine for COVID-19 (Convidecia Air). His contribution to the state of the art in fugitive medical and patient-derived aerosols was central to the evolution of several critical care consensus statements around the safe use of aerosol therapy during the COVID-19 pandemic.

Affiliations and expertise

Aerogen pty Ltd, Ireland

Hélder A. Santos

Prof. Santos (D.Sc. Tech., Chem. Eng.) is a Full Professor in Department of Biomedical Engineering at the University of Groningen. He is also Research Director at the University of Helsinki, Faculty of Pharmacy. Prof. Santos is also the co-founder of the startups Capsamedix Oy and Medixmicro Oy, and Coordinator of MSCA-ITN P4 FIT network in tendon repair (~4.1 m€). He holds Visiting Professorships at the Shanghai Jiao Tong University School of Medicine and University of Tartu. Prof. Santos research interests include the development of nanoparticles/nanomedicines and biomaterials for biomedical applications, particularly cancer and heart diseases. His lab makes the unique bridge between medical engineering, pharmaceutical nanotechnology and tissue engineering by combining unique techniques to develop novel therapeutic formulations for translation into the clinic. He is also in Editorial board member of several international journals, and Associate Editor of Nano Select, Smart Materials in Medicine, and Drug Delivery and Translational Research, among others. Prof. Santos has received prestigious awards/grants, for example, the "Talent Prize in Science" in 2010 attributed by the Portuguese Government, ERC Starting Grant in 2013 and ERC Proof-of-Concept Grant in 2018, Young Researcher Award in 2013 attributed by Faculty of Pharmacy, the Academy of Finland Award for Social Impact in 2016, and the CRS Young Investigator Award 2021.

Affiliations and expertise

Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland; Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland; Department of Biomedical Engineering, University Medical Center Groningen/University of Groningen, Groningen, The Netherlands

Saritha Shetty

Dr. Saritha Shetty Associate Professor, Pharmaceutics Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management SVKM’s NMIMS, V.L.Mehta Vile Parle (west), Mumbai, has a research experience of over 16 years working in the area of drug delivery and analytical method development. Before joining academics, she served as Scientist at Syngene International. Pvt. Ltd. (A Biocon Group), Bangalore, India. During this tenure, she has completed projects of major client like Baxter ACC – (Baxter Anesthesia Critical Care, USA) for analytical method development and validation using HPLC and GC. Dr. Shetty has her research interest in areas of developing drug delivery systems for infectious diseases. She has developed novel and effective formulations for topical and transdermal systems, mucoadhesive systems for respiratory and oral delivery. Edit

Affiliations and expertise

Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, India