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Mechanical Circulatory and Respiratory Support

  • 2nd Edition - October 23, 2024
  • Latest edition
  • Editors: Shaun D. Gregory, Andrew F. Stephens, Silver Heinsar, Jutta Arens, John F. Fraser
  • Language: English

Mechanical Circulatory and Respiratory Support, Second Edition, continues to provide a comprehensive overview of the past, present and future development of mechanical circulato… Read more

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Description

Mechanical Circulatory and Respiratory Support, Second Edition, continues to provide a comprehensive overview of the past, present and future development of mechanical circulatory and respiratory support devices. This new edition provides an update on the field while also introducing new elements within the field such as ex-vivo perfusion, devices for HFpEF, design for manufacture, oxygenator design, and more content on route to market.

Chapters from over 60 internationally-renowned experts focuses on the entire life-cycle of mechanical circulatory and respiratory support – from the descent into heart and lung failure, alternative medical management, device options, device design, implantation techniques, complications and medical management of the supported patient, patient-device interactions, cost effectiveness, route to market and a view to the future.

This second edition is a useful resource for biomedical engineers and clinicians who are designing new mechanical circulatory or respiratory support devices, while also providing a comprehensive guide of the entire field for those who are already familiar with some areas and want to learn more. Reviews of the most cutting-edge research are provided throughout each chapter, along with guides on how to design new devices and which areas require specific focus for future research and development.

Key features

  • Presents an engineering pathway to develop the most advanced medical devices
  • Features a clinical summary of how to select the right patients and treat them optimally while supported with these devices
  • Includes a detailed path to market for those developing new devices in this field

Readership

biomedical engineers, biomedical scientists and clinicians working in the field of mechanical cardiac and respiratory support

Table of contents

Section 1 - Before the Device

1. The Descent into Heart and Lung Failure

2. Heart and Lung Transplantation

3. Ex-vivo Organ Support

Section 2 - MCRS Devices

4. Ventricular Assist Devices: Volume Displacement Pumps

5. Ventricular Assist Devices: Rotary Blood Pumps

6. Total Artificial Hearts

7. Devices for HFpEF

8. Extracorporeal Membrane Oxygenation

Section 3 - Implantation and Medical Management

9. Optimising the Patient and Timing the Introduction of MCS

10. Surgical Implantation

11. Complications and Adverse Events

12. Medical Management of the Supported Patient

13. Pediatric devices

Section 4 - Device Design

14. Hydraulic Design

15. Motor design and Impeller Suspension

16. Design for Manufacture

17. Pulsatile vs Continuous Flow

18. Cannula Design

19. Oxygenator Design

Section 5 - Device/Patient Interaction

20. Blood-Device Interaction

21. Physiological Control

22. Systems for Power and Data Transfer

23. Wearable Systems

Section 6 - Route to Market

24. Route to Market

25. Preclinical Evaluation

26. Clinical trials

27. Cost Effectiveness

28. Regulatory approvals

Section 7 - Future

29. The Past, Present and Future

Product details

  • Edition: 2
  • Latest edition
  • Published: November 2, 2024
  • Language: English

About the editors

SG

Shaun D. Gregory

Shaun D. Gregory is a Cardiovascular Engineer with a focus on mechanical circulatory and respiratory support. He brings together multidisciplinary teams of engineering, biomedical science, design, and medicine to develop novel technical solutions for clinically relevant problems. Dr. Gregory is a Professor at the School of Mechanical, Medical, and Process Engineering at Queensland University of Technology (QUT), Director of the QUT Centre for Biomedical Technologies, Co-Director of the Artificial Heart Frontiers Program, Director of the Heart Hackathon international student team competition, and President-Elect of the International Society for Mechanical Circulatory Support.
Affiliations and expertise
Director, Innovative Cardiovascular Engineering and Technology Laboratory, Brisbane, Australia

AS

Andrew F. Stephens

Andrew F. Stephens is a Biomedical Engineer specializing in medical sensors and smart devices. He completed his PhD at Griffith University developing new ways to control artificial heart devices. Dr. Stephens is a Senior Lecturer at Queensland University of Technology and a Director of the Advanced Cardiorespiratory Engineering Laboratory.
Affiliations and expertise
Research Fellow, Monash University, Mechanical & Aerospace Engineering, Monash Data Futures Institute, Victorian Heart Institute (VHI), Australia

SH

Silver Heinsar

Silver Heinsar is an emerging Clinician Researcher at the University of Queensland with a focus on mechanical circulatory support and a special interest in extracorporeal membrane oxygenation. He completed his PhD at the University of Queensland, for which he received the Dean’s Award for Outstanding HDR Thesis. His contributions to ECMO research are internationally recognized as he is the first dual recipient of the prestigious European Extracorporeal Life Support Organization Young Investigator Award.
Affiliations and expertise
MD / PhD candidate, Critical Care Research Group, Faculty of Medicine, University of Queensland and The Prince Charles Hospital, Australia

JA

Jutta Arens

Jutta Arens is a Mechanical Engineer and a Professor in Engineering Organ Support Technologies at the University of Twente in the Netherlands. She completed her PhD and Habilitation at RWTH Aachen University, Germany. She is a member of the Board of Trustees of the American Society of Artificial Organs, the Scientific Advisory Board of the German Federal Institute of Drugs and Medical Devices (BfArM), and the International Standardization Organization´s ISO/TC 150/SC 2 working group 4–Extracorporeal Circuits.
Affiliations and expertise
Professor, University of Twente, Faculty of Engineering Technology, The Netherlands

JF

John F. Fraser

John F. Fraser is a Founder/Director of the Critical Care Research Group, a Director of the ICU at St Andrew’s War Memorial Hospital, and a President of Asia Pacific ELSO and holds five professorships across Australian universities. He is the Inaugural Ambassador for MedTech in his home state of Queensland. With more than 600 publications mainly in the heart and lung arena, he has been awarded numerous international awards for his research and continues to contribute to the education of generations of clinicians, scientists, and engineers.
Affiliations and expertise
Pre-eminent Staff Specialist in Intensive Care, Prince Charles Hospital, Brisbane, Australia

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