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Elsevier

Books in Life sciences

  • Foundations of Colorectal Cancer

    • 1st Edition
    • Alejandro Pazos Sierra
    • English
    Foundations of Colorectal Cancer provides a holistic and comprehensive dive into colorectal cancer, discussing the contributions of each discipline that studies it, allowing its understanding from the most demographic and ethical facts, to the treatment process, its varieties and genetic background. Written by experts in diverse areas such as cancer research, oncology, genetics, biochemistry, psychology, social sciences, bioinformatics and palliative care, the book brings real-world experiences to help readers with any challenge they may face when dealing with patients or during their research workflow.The content is split into nine sections: Clinical manifestations and disease detection, covering primary and secondary prevention, and the role of primary care; Diagnosis and staging, discussing endoscopy, colonoscopy, molecular pathology, and anatomopathological diagnosis; Treatment, including endoscopic, surgical, radiological, and postoperative approaches; Molecular and biological mechanisms, with the role of intestinal microbiota, stem cells and signaling pathways; New diagnostic methods, encompassing biomarkers and bioinformatics tools for research; Biobanks, with an overview of their regulations and importance in the research; Epidemiological studies, focusing on incidence and mortality globally and by regions; Hereditary colorectal cancer, differentiating nonpolyposis and polyposis types; and Addressing the consequences of colorectal cancer, covering psychological effects, nutrition and ethical issues.

  • Bark Beetle Management, Ecology, and Climate Change

    • 1st Edition
    • Kamal J.K. Gandhi + 1 more
    • English
    Bark Beetle Management, Ecology, and Climate Change provides the most updated and comprehensive knowledge on the complex effects of global warming upon the economically and ecologically important bark beetle species and their host trees. This authoritative reference synthesizes information on how forest disturbances and environmental changes due to current and future climate changes alter the ecology and management of bark beetles in forested landscapes. Written by international experts on bark beetle ecology, this book covers topics ranging from changes in bark beetle distributions and addition of novel hosts due to climate change, interactions of insects with altered host physiology and disturbance regimes, ecosystem-level impacts of bark beetle outbreaks due to climate change, multi-trophic changes mediated via climate change, and management of bark beetles in altered forests and climate conditions. Bark Beetle Management, Ecology, and Climate Change is an important resource for entomologists, as well as forest health specialists, policy makers, and conservationists who are interested in multi-faceted impacts of climate change on forest insects at the organismal, population, and community-levels.

  • Recombinant Protein Expression: Prokaryotic hosts and cell-free systems

    • 1st Edition
    • Volume 659
    • English
    Recombinant Protein Expression, Part A, Volume 659 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on Multiplexed analysis protein: Protein interactions of polypeptides translated in Leishmania cell-free system, MultiBac system and its applications, performance and recent, Production of antibodies in Shuffle, Designing hybrid-promoter architectures by engineering cis-acting DNA sites to enhance transcription in yeast, Designing hybrid-promoter architectures by engineering cis-acting DNA sites to deregulate transcription in yeast, Antibody or protein-based vaccine production in plants, Cell-free protein synthesis, Plant-based expression of biologic drugs, and much more. Additional sections cover the Use of native mass spectrometry to guide detergent-based rescue of non-native oligomerization by recombinant proteins, Advancing overexpression and purification of recombinant proteins by pilot optimization through tandem affinity-buffer exchange chromatography online with native mass spectrometry, Method for High-Efficiency Fed-batch cultures of recombinant Escherichia coli, Method to transfer Chinese hamster ovary (CHO) shake flask experiments to the ambr® 250, and Expression of recombinant antibodies in Leishmania tarentolae.

  • Red Panda

    Biology and Conservation of the First Panda
    • 2nd Edition
    • Angela R. Glatston
    • English
    Red Panda: Biology and Conservation of the First Panda, Second Edition, provides the most up-to-date research, data, and conservation solutions for the red pandas, Ailurus species. Since the publication of the previous edition in 2010, the International Union for Conservation of Nature (IUCN) updated the threat level of red pandas, and they are now considered to be endangered. This latest edition is updated to provide an in-depth look at the scientific and conservation-based issues urgently facing the red panda today. Led by one of the world’s leading authorities and advocates for red panda conservation, this new edition includes data from the Population and Habitat Viability (PHVA) workshops conducted in three of the species’ range states, Nepal, China, and India; these workshops utilized firsthand information on the decrease of red panda populations due to factors including deforestation, illegal pet trade, human population growth, and climate change. This book also includes updated information from the first edition on reproduction, anatomy, veterinary care, zoo management, and fossil history.

  • Biomolecular Interactions Part A

    • 1st Edition
    • Volume 166
    • English
    Biomolecular Interactions: Part A, Volume 166, the latest release in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics in cell biology. Each chapter is written by an international board of authors.

  • Mechanisms of Cell Death and Opportunities for Therapeutic Development

    • 1st Edition
    • Diaqing Liao
    • English
    Mechanisms of Cell Death and Opportunities for Therapeutic Development, volume four in the Perspectives in Translational Cell Biology series, offers content for professors, students and researchers across basic and translational biology. The book covers fundamental mechanisms, ranging from different forms of cell death and drug development, to efforts for treating disease, providing a valuable resource for readers interested in understanding cell death and relevant translational research. The book's editor, Diaqing Liao, has over twenty years’ experience teaching topics of cell death.

  • Biosensors for Single-Cell Analysis

    • 1st Edition
    • Jian Chen + 1 more
    • English
    Biosensors for Single-Cell Analysis explores a wide range of biosensor technologies and their applications in single-cell characterization and analysis. Sections cover key biophysical and chemical single-cell properties that consider proteomic, metabolic, electrical, mechanical and optical properties. Each chapter features key definitions and case studies, providing detailed guidance for researchers who want to replicate covered solutions in their work. Tutorial sections, evaluations of the current state-of-the-field and future developments are also included. Microfluidic approaches to characterization, such as microfluidic impedance flow cytometry and microfluidic flow cytometry are considered alongside more conventional approaches, such as mass spectroscopy, fluorescent and mass flow cytometry. Additionally, key types of biosensors are covered, including atomic force microscopy, micropipette aspiration, optical tweezers, microfluidic hydrodynamic stretchers, microfluidic constriction channel and microfluidic optical stretchers.

  • Chitosan in Drug Delivery

    • 1st Edition
    • Md Saquib Hasnain + 2 more
    • English
    Chitosan in Drug Delivery provides thorough insights into chitosan chemistry, collection, chemical modifications, characterization and applications in the pharmaceutical industry and healthcare fields. The book explores molecular weight, degree of deacetylation and molecular geometry, emphasizing recent advances in the field as written by academic, industry and regulatory scientists. It will be a useful resource for pharmaceutical scientists, including industrial pharmacists, analytical scientists, postgraduate students, health care professionals and regulatory scientists actively involved in pharmaceutical product and process development in natural polymers containing drug delivery.

  • Advances in Food Security and Sustainability

    • 1st Edition
    • Volume 6
    • Marc J. Cohen
    • English
    Advances in Food Security and Sustainability, Volume Six looks at the challenges, constraints and solutions necessary to maintain a healthy and accessible food supply in different communities. This ongoing series addresses a wide range of issues on food sustainability and security, with chapters in this release covering the Significance of Short Food Supply Chains During Pandemic Times, Food Security Challenges and Opportunities in Indonesia Post COVID-19, Understanding the genetic diversity and association mapping of nutritional traits in graminaceous crops: Progress and prospects, and Traditional foods and food security: Actors, production, and the challenge of integration into markets before and after the pandemic.

  • Tomato Processing by-Products

    Sustainable Applications
    • 1st Edition
    • Mejdi Jeguirim + 1 more
    • English
    In addition to being served as a fresh vegetable, tomato is also consumed in the form of various processed products, such as paste, juice, sauce, puree and ketchup. Generally, in processing these products, different by-products including peels, seeds and pulps are produced. The rational disposal of Tomato waste represents not only a resource problem but also an environmental and economic one for the Tomato Processing Industry. Tomato Processing By-Products: Sustainable Applications indicates the alternative sustainable solutions for the recovery of tomato processing by-products as a source for animal feed and valuable components as well as their possible approaches for value-added utilization in energy, environmental and agricultural applications. Aimed at agricultural or food engineers who work in the Tomato processing industry and are seeking to improve their by-products management by actively utilizing them in effective applications.

  • Nutraceutical and Functional Food Components

    Effects of Innovative Processing Techniques
    • 2nd Edition
    • Charis M. Galanakis
    • English
    Nutraceutical and Functional Food Components: Effects of Innovative Processing Techniques, Second Edition highlights the impact of recent food industry advances on the nutritional value, functional properties, applications, bioavailability, and bioaccessibility of food components. This second edition also assesses shelf-life, sensory characteristics, and the profile of food products. Covering the most important groups of food components, including lipids, proteins, peptides and amino acids, carbohydrates, dietary fiber, polyphenols, carotenoids, vitamins, aromatic compounds, minerals, glucosinolates, enzymes, this book addresses processing methods for each. Food scientists, technologists, researchers, nutritionists, engineers and chemists, agricultural scientists, other professionals working in the food industry, as well as students studying related fields, will benefit from this updated reference.

  • The Evolutionary Ecology of Invasive Species

    • 1st Edition
    • Johannes Le Roux
    • English
    The Evolutionary Ecology of Invasive Species offers new insights into the mechanisms that underlie rapid evolution in these species. The book provides a comprehensive overview of achievements in the field during the boom of information over the past two decades and includes discussions of possible future directions for the study of evolution in invasive species. Written by an international expert in invasion ecology, population genetics, and evolutionary biology, the book explores the roles of preadaptation, phenotypic plasticity, selection, and stochastic processes in driving rapid evolution. The book draws insights from a wide spectrum of invasive microbes, plants, and animals, covering many of the planet’s biogeographic regions and discusses the evolutionary consequences for native species in response to biological invasions. A valuable resource to researchers and students in evolutionary biology, invasive species biology, and global change biology, this text suggests future research directions related to the evolutionary biology, impacts, and management of invasive species.

  • TDP-43 and Neurodegeneration

    From Bench to Bedside
    • 1st Edition
    • Vijay Kumar + 1 more
    • English
    Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43’s structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases. This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders.

  • Clinical Signs in Humans and Animals Associated with Minerals, Trace Elements and Rare Earth Elements

    • 1st Edition
    • Mike Davies
    • English
    The first book to compile the clinical signs associated with deficiencies, toxicities, imbalances, or exposures to minerals, trace elements, and rare earth elements in humans and animal species, Clinical Signs in Humans and Animals Associated With Minerals, Trace Elements, and Rare Earth Elements aims to increase awareness to improve diagnosis and to encourage further investigation based on comparative data. Written by an experienced veterinary clinician having worked in private practice, academia, and pharmaceutical and pet food industries, this book includes data on humans and primates, as well as companion animals, horses, rabbits, reptiles, ruminants, poultry, fish, and species typical in zoo populations. The subject material is divided into three sections to provide easy access to information on clinical signs, specific elements, or species. This book is written for medical and veterinary researchers, clinicians, and practitioners, specifically those working with animal nutrition and animal feed health. Academics and public health scientists will also benefit from the book’s information and data on rehabilitating and maintaining animal health.

  • Porous Silicon for Biomedical Applications

    • 2nd Edition
    • Hélder A. Santos
    • English
    Porous Silicon for Biomedical Applications, Second Edition, provides an updated guide to the diverse range of biomedical applications of porous silicon, from biosensing and imaging to tissue engineering and cancer therapy. Across biomedical disciplines, there is an ongoing search for biomaterials that are biocompatible, modifiable, structurally sound, and versatile. Porous silicon possesses a range of properties that make it ideal for a variety of biomedical applications, such as controllable geometry, tunable nanoporous structure, large pore volume/high specific surface area, and versatile surface chemistry. This book provides a fully updated and detailed overview of the range of biomedical applications for porous silicon. Part One offers the reader a helpful insight into the fundamentals and beneficial properties of porous silicon, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein modification, and biocompatibility. The book then builds on the systematic detailing of each biomedical application using porous silicon, from bioimaging and sensing to drug delivery and tissue engineering. This new edition also includes new chapters on in-vivo assessment of porous silicon, photodynamic and photothermal therapy, micro- and nanoneedles, Raman imaging, cancer immunotherapy, and more. With its acclaimed editor and international team of expert contributors, Porous Silicon for Biomedical Applications, Second Edition, is a technical resource and indispensable guide for all those involved in the research, development, and application of porous silicon and other biomaterials, while providing a comprehensive introduction for students and academics interested in this field.

  • Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS Part I

    • 1st Edition
    • Volume 160
    • English
    Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS, Volume 161 in the International Review on Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics including Cannabis Exposure During Adolescence: A Uniquely Sensitive Period for Neurobiological Effects, The Stoned-Age: A Systematic Review of the Neurobiological Effects of Adolescent Cannabinoid Exposure on Preclinical Animal Models, Genetic Influences Impacting Nicotine Use and Abuse During Adolescence: Insights from Human and Animal Studies, the Impact of Adolescent Nicotine Exposure on Adulthood Alcohol Consumption: The Role of Neuropeptides, and much more. Additional chapters cover The Role of Sex in the Persistent Effects of Adolescent Alcohol Exposure on Behavior and Neurobiology in Rodents, The Effects of Peri-Adolescent Alcohol Use on the Developing Hippocampus, Regulation of Glutamate Signaling in the Extended Amygdala by Adolescent Alcohol Exposure, Peri-Adolescent Binge Drinking Effects on Hippocampal Neurogenesis, Neuroepigenetic Consequences of Adolescent Ethanol Exposure, Adolescent Neuroimmunity and Its Interaction with Alcohol, and much more.

  • Forensic Toxicology

    Principles and Concepts
    • 2nd Edition
    • Nicholas T. Lappas + 1 more
    • English
    **Selected for Doody’s Core Titles® 2024 in Toxicology**The second edition of Forensic Toxicology: Principles and Concepts takes the reader back to the origins of forensic toxicology providing an overview of the largely unchanging principles of the discipline. The text focuses on the major tenets in forensic toxicology, including an introduction to the discipline, principles of forensic toxicology including pharmacokinetics, pharmacodynamics, drug interactions and toxicogenomics, fundamentals of forensic toxicology analysis, types of interpretations based on analytical forensic toxicology results, and reporting from the laboratory to the courtroom. Also included in the second edition is a Unit focused on the forensic toxicology of individual drugs of abuse.

  • Translational Autoimmunity, Volume 1

    Etiology of Autoimmune Diseases
    • 1st Edition
    • Nima Rezaei
    • English
    Translational Autoimmunity: Etiology of Autoimmune Diseases is the first volume of the Translational Immunology book series. To attain its purpose as a detailed translational step to tackle autoimmunity, this volume sufficiently addresses basic questions on how the immune system is designed to distinguish self from nonself. It discusses the known mechanisms that lead to the maintenance of self-tolerance, presents potential triggers and malfunctions that impede normal immune processes, and demonstrates how the immune system induces an autoreactive state that results in the recognition of self-antigens seen in autoimmune conditions.

  • Viral Replication Enzymes and their Inhibitors Part A

    • 1st Edition
    • Volume 49
    • English
    Viral Replication Enzymes and their Inhibitors Part A, Volume 49, the latest release in the Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of related topics.

  • Cellular Mechanotransduction Mechanisms in Cardiovascular and Fibrotic Diseases

    • 1st Edition
    • Volume 87
    • English
    Endothelial Signaling, Mechanotransduction, Vascular Biology and Atherosclerosis, Volume 87, the latest release in the Current Topics in Membranes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors.

  • Artificial Intelligence and Big Data Analytics for Smart Healthcare

    • 1st Edition
    • Miltiadis Lytras + 3 more
    • English
    Artificial Intelligence and Big Data Analytics for Smart Healthcare serves as a key reference for practitioners and experts involved in healthcare as they strive to enhance the value added of healthcare and develop more sustainable healthcare systems. It brings together insights from emerging sophisticated information and communication technologies such as big data analytics, artificial intelligence, machine learning, data science, medical intelligence, and, by dwelling on their current and prospective applications, highlights managerial and policymaking challenges they may generate. The book is split into five sections: big data infrastructure, framework and design for smart healthcare; signal processing techniques for smart healthcare applications; business analytics (descriptive, diagnostic, predictive and prescriptive) for smart healthcare; emerging tools and techniques for smart healthcare; and challenges (security, privacy, and policy) in big data for smart healthcare. The content is carefully developed to be understandable to different members of healthcare chain to leverage collaborations with researchers and industry.

  • Data Science for COVID-19

    Volume 2: Societal and Medical Perspectives
    • 1st Edition
    • Utku Kose + 3 more
    • English
    Data Science for COVID-19, Volume 2: Societal and Medical Perspectives presents the most current and leading-edge research into the applications of a variety of data science techniques for the detection, mitigation, treatment and elimination of the COVID-19 virus. At this point, Cognitive Data Science is the most powerful tool for researchers to fight COVID-19. Thanks to instant data-analysis and predictive techniques, including Artificial Intelligence, Machine Learning, Deep Learning, Data Mining, and computational modeling for processing large amounts of data, recognizing patterns, modeling new techniques, and improving both research and treatment outcomes is now possible.

  • Analytical Techniques in Biosciences

    From Basics to Applications
    • 1st Edition
    • Chukwuebuka Egbuna + 4 more
    • English
    Analytical Techniques in Biosciences: From Basics to Applications presents comprehensive and up-to-date information on the various analytical techniques obtainable in bioscience research laboratories across the world. This book contains chapters that discuss the basic bioanalytical protocols and sample preparation guidelines. Commonly encountered analytical techniques, their working principles, and applications were presented. Techniques, considered in this book, include centrifugation techniques, electrophoretic techniques, chromatography, titrimetry, spectrometry, and hyphenated techniques. Subsequent chapters emphasize molecular weight determination and electroanalytical techniques, biosensors, and enzyme assay protocols. Other chapters detail microbial techniques, statistical methods, computational modeling, and immunology and immunochemistry.The book draws from experts from key institutions around the globe, who have simplified the chapters in a way that will be useful to early-stage researchers as well as advanced scientists. It is also carefully structured and integrated sequentially to aid flow, consistency, and continuity. This is a must-have reference for graduate students and researchers in the field of biosciences.

  • Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A

    • 1st Edition
    • Volume 365
    • English
    Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A, Volume 365 in the International Review of Cell and Molecular Biology series reviews and details current advances in cell and molecular biology. Chapters in this new release include MPN a continuum of different disease entities, Bone marrow microenvironment of MPN, Extramedullary hemopoiesis in MPN, The JAK2 mutation, Calreticulin mutations in myeloproliferative neoplasms, and Cytogenetic abnormalities and non-driver mutations in MPN. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. The articles published in IRCMB have a high impact and an average cited half-life of 9 years. This great resource ranks high amongst scientific journals dealing with cell biology.

  • Innovation Strategies in the Food Industry

    Tools for Implementation
    • 2nd Edition
    • Charis M. Galanakis
    • English
    Innovation Strategies for the Food Industry: Tools for Implementation, Second Edition explores how process technologies and innovations are implemented in the food industry, by i.e., detecting problems and providing answers to questions of modern applications. As in all science sectors, Internet and big data have brought a renaissance of changes in the way academics and researchers communicate and collaborate, and in the way that the food industry develops. The new edition covers emerging skills of food technologists and the integration of food science and technology knowledge into the food chain. This handbook is ideal for all relevant actors in the food sector (professors, researchers, students and professionals) as well as for anyone dealing with food science and technology, new products development and food industry.

  • Psychological and Medical Perspectives on Fertility Care and Sexual Health

    • 1st Edition
    • Kim Bergman + 1 more
    • English
    Psychological and Medical Perspectives on Fertility Care and Sexual Health provides the necessary specialized training of sexual dysfunction and sex therapy to those in reproductive medicine. Understanding and knowledge about these sexual dysfunctions is needed for reproductive specialists to identify sexual problems, provide treatment if they are able or make appropriate referrals, and coordinate care for more specialized and specific needs as part of the patients overall reproductive medical management. This must-have reference explores the intimate interface of sexuality and fertility, male and female sexual function, cultural influences on women, Eastern medicine, and more!

  • Coronavirus Disease

    From Origin to Outbreak
    • 1st Edition
    • Adnan I. Qureshi + 2 more
    • English
    Coronavirus Disease: From Origin to Outbreak provides a comprehensive review of coronaviruses, particularly COVID-19, its transmission, and disease pathology. The book covers the viral structure and genetics of coronaviruses, the pathogenesis and unique characteristics of coronavirus infection, and the evolving nature of our understanding of coronaviruses and disease. It also looks at the history of SARS-CoV and MERS-CoV infections and its global spread. The book examines the effectiveness of various preventive measures and new therapeutic agents that are either currently available or expected to available. Finally, it details the psychological and societal impact the virus and disease has in outbreak regions and what the financial impact an outbreak has on the healthcare system and local economies.

  • Bioinformatics

    Methods and Applications
    • 1st Edition
    • Dev Bukhsh Singh + 1 more
    • English
    Bioinformatics: Methods and Applications provides a thorough and detailed description of principles, methods, and applications of bioinformatics in different areas of life sciences. It presents a compendium of many important topics of current advanced research and basic principles/approache... easily applicable to diverse research settings. The content encompasses topics such as biological databases, sequence analysis, genome assembly, RNA sequence data analysis, drug design, and structural and functional analysis of proteins. In addition, it discusses computational approaches for vaccine design, systems biology and big data analysis, and machine learning in bioinformatics.It is a valuable source for bioinformaticians, computer biologists, and members of biomedical field who needs to learn bioinformatics approaches to apply to their research and lab activities.

  • Spinal Cord Injury Pain

    • 1st Edition
    • Christine N. Sang + 1 more
    • English
    Spinal Cord Injury Pain presents the basis for preclinical and clinical investigations, along with strategies for new approaches in the treatment of central neuropathic pain. Contributors from the private sector and academia provide a comprehensive review of state-of-the-art research in this challenging space. Topics include Epidemiology of Chronic Pain Following SCI, experimental models and mechanisms of chronic pain in SCI, and new targets and technologies. This book serves as a resource for continued translational research that will result in novel approaches and treatments that improve function and quality of life for individuals with CNP/SCI. Despite a better understanding of the complexity of mechanisms of CNP/SCI, improved medical and surgical management of SCI, and the subsequent acceleration of the identification of new targets and the development of novel analgesics, there is still a great unmet clinical need in the area of CNP following SCI. Hence, this book is a welcomed addition to current research and developments.

  • Advances in Parasitology

    • 1st Edition
    • Volume 114
    • David Rollinson + 1 more
    • English
    Advances in Parasitology, Volume 114, the latest release in this ongoing series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history. Chapters in this update include Global Health Governance and the World Health Organization during COVID-19: Current and future impact on control of parasitic diseases towards WHO 2030 targets, Combatting Anthelmintic Resistance in Ruminants, New insights into the Cryptosporidium and cryptosporidiosis in human health and beyond, Control And Elimination Of Lymphatic Filariasis In Oceania: Prevalence, Geographical Distribution, Mass Drug Administration, and Surveillance In Samoa, 1998 To 2017.

  • Prenatal Genetic Counseling

    Practical Support for Prenatal Diagnostics, Decision-Making, and Dealing with Uncertainty
    • 1st Edition
    • Sam Riedijk + 1 more
    • English
    **Selected for Doody’s Core Titles® 2024 in Clinical Genetics**Prenatal Genetic Counseling: Practical Support for Prenatal Diagnostics, Decision-Making, and Dealing with Uncertainty provides a foundation for new research and a one-stop source for physicians, genetic counselors, psychologists, social workers, general practitioners, grief workers, translational researchers, and administrators seeking to work in the field of clinical genomics ethically and in full consideration of patients’ psychological well-being. Here, an international team of experienced counselors and clinician-scientists lay out the range of methods and technologies applied in prenatal decision-making, including NIPT; invasive testing with microarray analysis or whole genome sequencing; ultrasound screening; and prenatal diagnosis for known hereditary conditions, among others. From here, they examine specific challenges in the clinical translation. In a field where decisions about life or death of a child are made, professionals are bound to encounter uncertainty. This book was co-created by health care practitioners, scientists, patients and students to provide insights and direction for offering support straight from the heart to couples faced with fetal anomalies. To make this possible for all couples, diversity in prenatal genetic counseling is also addressed. Finally, next steps in prenatal genetic counseling research and clinical implementation are discussed. As we are challenged by the rapid advances in prenatal genomics, so are our patients. Learning from our patients with every encounter, this book aims to offer access to the insights we gathered as well as to stimulate lifelong learning.

  • Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 1: Principles and Practice of Toxicologic Pathology

    • 4th Edition
    • Wanda M. Haschek + 3 more
    • English
    Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to four separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, Volume 1, "Principles and the Practice of Toxicologic Pathology," covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Other volumes in this work round out the depth and breadth of coverage.Volume 2 encompasses "Toxicologic Pathology in Safety Assessment" and "Environmental Toxicologic Pathology". These two sections cover the application of toxicologic pathology in developing specific product classes, principles of data interpretation for safety assessment, and toxicologic pathology of major classes of environmental toxicants. Volumes 3 and 4 provide deep and broad treatment of "Target Organ Toxicity", emphasizing the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. These volumes comprise the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately.　

  • Medical Pharmacology and Therapeutics

    • 6th Edition
    • Derek G. Waller + 1 more
    • English
    Medical Pharmacology & Therapeutics provides all the information medical and healthcare students need throughout their degree programme and beyond, including for professional qualifications such as the PSA.This all-round textbook covers basic pharmacology through to drug prescribing in clinical contexts, covering the pathogenic mechanisms of disease; drug actions, side effects, and the therapeutic principles of drug use. It takes a helpful systems-based approach that orders information according to body systems and disease areas, rather than by drug class.Now in its sixth edition, the book has been fully updated to include latest scientific understanding of drug action and administration and current best practice in prescribing medications, informed by the latest national guidelines.

  • Infinity Fish

    Economics and the Future of Fish and Fisheries
    • 1st Edition
    • Ussif Rashid Sumaila
    • English
    Infinity Fish: Economics and the Future of Fish and Fisheries is a practical and science-based reference that demonstrates how to value the benefits from restored marine ecosystems to sustain ocean and fishery resources for years to come. It discusses ecological and economical aspects to support the preservation of marine resources by understanding cost-benefits of fishery management systems. The book explains the economic benefits of restoring ecosystems that have been overexploited and how to maintain fisheries in a sustainable level. Infinity Fish: Economics and the Future of Fish and Fisheries is a useful reference to a wide range of audiences. It is for those who wish to make systematic efforts to develop their fisheries sector, scientists and researchers, anyone in fisheries management, marine resource management, economists, fish farmers, policy makers, leaders and regulators, operations researchers, as well as faculty and students.　

  • CRISPR Genome Surgery in Stem Cells and Disease Tissues

    • 1st Edition
    • Stephen H. Tsang
    • English
    CRISPR Genome Surgery in Stem Cells and Disease Tissues focuses uniquely on the clinical applications of CRISPR/Cas9 based technology. Topics include the latest advances in gene editing and its translational applications to various diseases, including retinal degenerative disease, recessively inherited diseases, and dominantly inherited diseases, to name a few. The book's target audience includes researchers, students, clinicians and the general public. This space that is not currently served by any existing resource, so this publication fills a gap in current literature.

  • Fish Nutrition

    • 4th Edition
    • Ronald W. Hardy + 1 more
    • English
    Fish Nutrition, Fourth Edition is an up-to-date, authoritative presentation of all key elements of the nutrition of fish and crustaceans. As aquaculture is rapidly expanding, more than 200 herbivorous and carnivorous species occupy a diverse range of ecological niches, and have therefore evolved to utilize a wide array of food sources. This new edition highlights these differences and covers the complexity and challenges associated with fish nutrition, addressing nutrient requirements to produce high-quality, healthful and sustainable resources, the essential nutrients for fish species, including proteins and amino acids, vitamins, minerals and essential fatty acids, a feed quality assessment, and fish pathology. Led by a team of international experts, this edition provides readers with new information on the use of high-throughput technologies in fish nutrition research, the role of feeds on the community structure of the microbiome, and advances in essential nutrient requirements.

  • Atkinson's Principles of Clinical Pharmacology

    • 4th Edition
    • Shiew-Mei Huang + 3 more
    • English
    **Selected for Doody’s Core Titles® 2024 in Pharmacology**Atkins... Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology.

  • Advances in Virus Research

    • 1st Edition
    • Volume 111
    • Thomas Mettenleiter + 2 more
    • English
    Advances in Virus Research, Volume 111, the latest release in a serial that highlights new advances in the field, presents interesting and timely chapters authored by an international board of subject matter experts.

  • Comorbilidad en trastornos psicóticos

    Hacia una mejora del diagnóstico y el abordaje
    • 1st Edition
    • André Barciela Veras + 1 more
    • Spanish
    Obra que detalla con gran pericia los datos que respaldan un innovador enfoque para subclasificar la esquizofrenia y otros trastornos psicóticos en base a las comorbilidades de ansiedad y depresión. Proporciona casos prácticos simulados, criterios diagnósticos del DSM-5, modelos de entrevista específicos para cada una de las cinco comorbilidades en pacientes con psicosis y opciones terapéuticas mejoradas. También se analizan las psicosis relacionadas con el consumo de sustancias, las enfermedades médicas y el tratamiento médico, así como otros factores que contribuyen a los trastornos psicóticos. Esta pionera obra de referencia, única en su área, es un recurso clínico, docente, de investigación y de formación, útil para psiquiatras, psicólogos, profesionales de enfermería, trabajadores sociales, neurólogos y cualquiera que esté interesado en la asistencia y el tratamiento de pacientes con trastornos psicóticos. La obra incluye ejemplos de entrevistas con los pacientes y/o purebas de laboratorio para cada diagnóstico. Detalla los síntomas, cuasipsicóticos y los signos secundarios de las comorbilidades, tanto cuando aparecen de forma aislada como asociados a psicosis. Subraya el significado específico de cada diagnóstico y los papeles contribuyentes de los neurotransmisores, la hipofrontalidad, los traumas psicológicos y la genética.

  • Biomedical Innovations to Combat COVID-19

    • 1st Edition
    • Sergio Rosales-Mendoza + 2 more
    • English
    Biomedical Innovations to Combat COVID-19 provides an updated overview on the development of vaccines, antiviral drugs and nanomaterials, and diagnostic methods for the fight against COVID-19. Perspectives on such technologies are identified, discussed, and enriched with figures for easy understanding and applicability. Furthermore, it contains basic aspects of virology, immunology, and antiviral drugs that are needed to fully appreciate these innovations. This book is split into four sections: introduction, presenting basic virologic and epidemiological aspects of COVID-19; vaccines against COVID-19, discussing their different types and applications used to develop them; diagnostic approaches for SARS-CoV-2, encompassing advanced sensing and microfluidic-based biosensors; and drug development and delivery, where antivirals based on nanomaterials or drugs are presented. It is a valuable source for virologists, biotechnologists, and members of biomedical field interested in learning more about how novel technologies can be applied to fasten the eradication of the COVID-19 and similar pandemics.

  • Success Is What You Leave Behind

    Fostering Leadership and Innovation
    • 1st Edition
    • Cato Laurencin
    • English
    Success Is What You Leave Behind: Fostering Leadership and Innovation reveals the 16 proven practices that Dr. Cato T. Laurencin has used to build his distinguished career as a renowned orthopedic surgeon, biomedical engineer, educator and mentor. Dr. Laurencin shares his own experiences and how one can utilize them in their own career. The book discusses how to be a leader, how to handle challenging moments, how to foster creativity and innovation, how to use skills and successes to help others, and what he has learned from some of the giants in the world of the life sciences and medicine.

  • The Inequality of COVID-19

    Immediate Health Communication, Governance and Response in Four Indigenous Regions
    • 1st Edition
    • Eric E. Otenyo + 1 more
    • English
    The Inequality of COVID-19: Immediate Health Communication, Governance and Response in Four Indigenous Regions explores the use of information, communication technologies (ICTs) and longer-term guidelines, directives and general policy initiatives. The cases document implications of the failure of various governments to establish robust policies to mitigate the spread of COVID-19 in a sample of advanced and low-income countries. Because the global institutions charged with managing the COVID-19 crisis did not work in harmony, the results have been devastating. The four Indigenous communities selected were the Navajo of the southwest United States, Siddi people in India, Aboriginal and Torres Strait Islander peoples of Australia and the Maasai in East Africa. Although these are all diverse communities, spread across different continents, their base economic oppression and survival from colonial violence is a common denominator in hypothesizing the public health management outcomes. However, the research reveals that national leadership and other incoherent pandemic mitigation policies account for a significant amount of the devastation caused in these communities.

  • Vascular Surgery

    A Clinical Guide to Decision-making
    • 1st Edition
    • Piergiorgio Settembrini + 1 more
    • English
    Vascular Surgery: A Clinical Guide to Decision-making is a concise but comprehensive resource for operating vascular surgeons and clinicians. It serves as an essential reference manual, particularly to young vascular surgeons, for consulting the basic scientific knowledge of pathogenesis of various illnesses, as well as how to approach them in a clinical setting. Adopting a translational approach, this book dissects the background of vascular pathology and links it to application in surgical techniques, as well as providing practical tips and tricks for surgical maneuvers. With insights and suggestions from various experienced and skilled vascular surgeons, this book covers a range of topics including the origin of diseases, clinical presentation, and therapeutic options, from medical therapy to surgical or endovascular approach. Each chapter also reviews international cutting-edge research in the vascular field and its clinical application, illuminating future developments in the field. With the contributions of first-class vascular surgeons, this book also covers uncommon and advanced case studies while exploring the pros and cons of each intervention option, helping practitioners make informed decisions when facing difficult cases. This unique reference also helps young surgeons to make quick decisions in challenging cases, such as how to choose between open and endo treatment.

  • Principles of Nucleic Acid Structure

    • 2nd Edition
    • Stephen Neidle + 1 more
    • English
    Principles of Nucleic Acid Structure, Second Edition, provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussions of X-ray crystallography, NMR, molecular modelling and databases. The book's focus is on a survey of structures that are especially important for biomedical research and pharmacological applications. This updated edition includes the latest advances relevant to recognition of DNA and RNA by small molecules and proteins, including sections on RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes and short interfering RNA (siRNA).This reference is a must-have for those seeking an authoritative, comprehensive and up-to-date source on all aspects of nucleic acid structure, from basic first principles to details of recent research results.

  • Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C

    • 1st Edition
    • Volume 183
    • English
    Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C, Volume 183 represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this volume include discussions on the evolution of disorder, consideration of the peculiarities of phase separation of the prion protein, a general discussion of the relationships between intrinsic disorder and protein functions, coverage of the structural and functional characterization of several important intrinsically disordered proteins, such as transcription factors, outer membrane porins, trans-membrane and membrane associated proteins with ID regions, discussion of molecular simulations of IDPs, and much more.

  • Spider Evolution

    Genetics, Behavior, and Ecological Influences
    • 1st Edition
    • Subir Ranjan Kundu
    • English
    Spider Evolution: Genetics, Behavior, and Ecological Influences provides a thorough exploration of the evolutionary trail of arachnids, particularly spider species, from prehistoric origins to current sustainability issues. This book analyzes extinct organisms in the Arachnida class, specifically looking at their phylogenomics and molecular footprints to understand evolutionary changes in diversification in today’s species. Sections cover spider origins and their influences on behavioral traits, physiology of sensory organs, and biomechanics, also touching on spiders as prey and predators and how their roles have changed in the 400 million years of Arachnida existence. The book then focuses upon current environmental issues facing spider species and how these have, and can, affect the evolution of these organisms. Topics include biodiversity minimization, climate change and natural disasters. This book is a much-needed resource for entomologists and arachnid- or arthropod-driven researchers. Advanced undergraduate and graduate students will also benefit from the historic review, current assessment and future predictions of spider evolution provided in this book.

  • Advances in Immunology

    • 1st Edition
    • Volume 151
    • Frederick W. Alt
    • English
    Advances in Immunology, Volume 151, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.

  • Pediatric Headache

    • 1st Edition
    • Jack Gladstein + 2 more
    • English
    Covering the topic of headache in children from the viewpoint of both primary care and neurology, Pediatric Headache provides concise, authoritative guidance on all aspects of this multifaceted subject. Drs. Jack Gladstein, Christina Szperka, and Amy Gelfand, each an expert in pediatric headache, contribute their considerable knowledge and expertise to assist neurologists, pediatricians, and primary care providers in providing optimal care to young patients.

  • Proteolytic Signaling in Health and Disease

    • 1st Edition
    • Andre Zelanis
    • English
    In recent years, powered by evolving technologies and experimental design, studies have better illuminated the regulating role of proteolytic enzymes across human development and pathologies. Proteolytic Signaling in Health and Disease provides an in-depth discussion of fundamental physiological and developmental processes regulated by proteases, from protein turnover and autophagy to antigen processing and presentation and major histocompatibility complex (MHC) molecules. Moving on from basic biology, international chapter authors examine a range of pathological conditions associated with proteolysis, including inflammation, wound healing, and cancer. Later chapters discuss the newly discovered network of connected events among proteases (and their inhibitors), the so-called ‘protease web’, and how best to study it. This book also empowers new research with up-to-date analytical methods and step-by-step protocols for studying proteolytic signaling events.

  • History of Modern Clinical Toxicology

    • 1st Edition
    • Alan Woolf
    • English
    History of Modern Clinical Toxicology describes the extraordinary advances in the practice of clinical toxicology within the past 70 years and brings together stories of the people – the champions of clinical toxicology - who contributed to these advances, discovered new therapies and antidotes, and made change happen. This book lays out the poison control system they built and the fascinating story of how they created a new and evolving medical specialty. With the participation of renowned international experts as authors, the book showcases the development of poison control centers around the world and the growth of the professional societies that represent and support them today. This book also tells the stories of the modern-day toxic disasters and recent toxic exposures that gained worldwide attention and notoriety. It outlines the public health responses to such calamities which have led to improvements in our understanding of the science and changes in public health policies and regulations to forestall future such events. Finally, the book covers key policies and agencies affecting poison control centers, addresses the challenges facing clinical toxicologists of today, and predicts advances and future innovations in the field. History of Modern Clinical Toxicology is a unique resource that provides the historical and international perspective that will help students, practitioners, scientists, and health policy makers put current issues and methods in perspective. It will help them understand how infrastructure and processes in clinical toxicology have evolved and why poison control systems are configured as they are.

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