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Advanced Biosensors for Virus Detection

Smart Diagnostics to Combat SARS-CoV-2

  • 1st Edition - March 4, 2022
  • Latest edition
  • Editors: Raju Khan, Arpana Parihar, Ajeet Kumar Kaushik, Ashok Kumar
  • Language: English

Advanced Biosensors for Virus Detection: Smart Diagnostics to Combat Against the SARS-CoV2 Pandemic covers the development of biosensor-based approaches for the diagnosis and progn… Read more

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Description

Advanced Biosensors for Virus Detection: Smart Diagnostics to Combat Against the SARS-CoV2 Pandemic covers the development of biosensor-based approaches for the diagnosis and prognosis of viral infections, specifically coronaviruses. The book discusses wide-ranging topics of available biosensor-based technologies and their application for early viral detection. Sections cover the emergence of SARS-CoV, MERS-CoV and SARS-CoV2, the global health response, the impact on affected populations, state-of-the art biomarkers, and risk factors. Specific focus is given to COVID-19, with coverage of genomic profiling, strain variation and the pathogenesis of SARS-CoV2.

In addition, current therapeutics, nano-abled advancements and challenges in the detection of SARS-CoV2 and COVID-19 management are discussed, along with the role of nanomaterials in the development of biosensors and how biosensors can be scaled up for clinical applications and commercialization.

Key features

  • Deals with biosensors-based approaches that could be exploited to design and develop high throughput, rapid and cost-effective diagnostics technologies for the early detection of viral infections
  • Illustrates the development of multiplexed, miniaturized analytical systems for point-of-care applications
  • Provides information about fabrication protocols for various biosensor based diagnostic approaches that could be directly implemented to develop a novel biosensor
  • Includes the past, present and future status of biosensors, along with information about biosensors currently under clinical trials

Readership

Virologists, clinicians, biomedical engineers, pathologists, molecular biologists, medical practitioners, analytical chemists and academics

Table of contents

1. Emergence of coronavirus epidemic and pandemic

2. Emergence of novel coronavirus (SARS-COV-2) and global public health response

3. Lessons learned from coronavirus (SARS-CoV, MERS-CoV and SARS-CoV2) and Socio-economic impact of (SARS-COV-2) pandemic

4. Current therapeutics for COVID-19 management

5. Exploring SARS-COV-2 genomic profiling and strain variation

6. Profiling and pathogenesis of SARS-CoV2

7. Nano-enabled advancements in COVID-19 management

8. Challenges in SARS-CoV2 detection needed to management COVID-19 pandemic

9. State-of-the-art diagnostic to manage coronavirus epidemic and pandemic

10. Biomarkers and risk factors associated with coronavirus infection

11. Protein Biomarkers

12. Genomic Biomarkers

13. Patients fluid as antibody

14. Biological/Synthetic Receptors used for Biosensors development for coronavirus detection
(a) Antibody based
(b) Enzyme based
(c) Aptamer based

15. Electrochemical biosensors for viral infection diagnostics

16. Optical Biosensors for viral infection diagnostics

17. Calorimetric Biosensors for viral infection diagnostics

18. Role of Magnetic nanoparticles in development of Biosensors for viral infection diagnostics

19. Advances in nanomaterials for biosensor development for virus detection

20. Multiplexed biosensors for virus detection

21. Acoustic/electrical biosensors for diagnostic approaches

22. Role of mechanical biosensors in diagnostic approaches

23. Fluorescence Based Biosensors for coronavirus infection diagnostics

24. Raman based biosensors for coronavirus infection diagnostics

25. Miniaturized analytical system for Point-of-care coronavirus infection diagnostics

26. Microfluidic Device with Integrated Biosensors for coronavirus infection diagnostics

27. Currently available Biosensor based approaches for SARS-CoV-2 detection

28. Biosensors based approaches for other viral infection detection

29. Lab-on-chip devices for coronavirus infection diagnostics

30. Scaling up of biosensors for clinical applications and commercialization

31. Future aspects of biosensor-based devices in disease detection

Product details

  • Edition: 1
  • Latest edition
  • Published: March 4, 2022
  • Language: English

About the editors

RK

Raju Khan

Raju Khan is a Senior Principal Scientist and Professor, at CSIR-Advanced Materials and Processes Research Institute, Bhopal. He did his PhD in Chemistry in 2005 from Jamia Millia Islamia, Central University, New Delhi, and Postdoctoral researcher at the “Sensor Research Laboratory” University of the Western Cape, Cape Town. His current research involved synthesizing novel materials to fabricate electrochemical and fluorescence-based biosensors integrated with microfluidics to detect target disease risk biomarkers for health care monitoring. He has published over 150 papers in SCI journal, which attracted over 5500 citations as per Google Scholar, published 45 book chapters in the reputed book Elsevier and Taylor Francis, editing of 28 books from Elsevier and Taylor Francis, and his research has been highlighted in Nature India. He has supervised 5 PhD and 30 undergraduate/postgraduate theses and has supervised 4 numbers of postdoctoral fellows under the scheme of N-PDF, CSIR-Nehru Fellowship, and DST-Women Scientist Projects.

Affiliations and expertise
Senior Principal Scientist and Professor, CSIR-Advanced Materials & Processes Research Institute, Bhopal, Madhya Pradesh, India

AP

Arpana Parihar

Arpana Parihar is a DST Scientist B at CSIR-Advanced Materials and Processes Research Institute (AMPRI), Bhopal, India. She has 8 years of research and teaching experience and her current research interests include fabrication (Micro/Nano-fabrication) of Bio-devices/bio-medical POCT Devices for early diagnosis of cancer and infectious disease. She has gained significant expertise in the field of 3D cell culture, drug designing, tissue engineering, photodynamic therapy, molecular dynamic simulations, and immunoinformatics.
Affiliations and expertise
Industrial Waste Utilization, Nano and Biomaterials, CSIR-Advanced, Materials and Processes, Research Institute (AMPRI), Bhopal, Madhya, Pradesh, India

AK

Ajeet Kumar Kaushik

Dr. Ajeet Kaushik is Associate Professor at the NanoBioTech Laboratory, Department of Environmental Engineering, Florida Polytechnic University, USA. He is the recipient of various reputed awards for his service in the area of nano-biotechnology for health care. He has edited seven books, written more than 100 international research peer reviewed publications, and has three patents in the area of nanomedicine and smart biosensors for personalized health care. In the course of his research, Dr. Kaushik has been engaged in the design and development of various electro-active nanostructures for electrochemical biosensor and nanomedicine for health care. His research interests include nanobiotechnology, analytical systems, design and develop nanostructures, nano-carries for drug delivery, nano-therapeutics for CNS diseases, on-demand site-specific release of therapeutic agents, exploring personalized nanomedicines, biosensors, point-of-care sensing devices, and related areas of health care monitoring.

Affiliations and expertise
Associate Professor of Chemistry, NanoBioTech Laboratory, Health System Engineering, Department of Environmental Engineering, Florida Polytechnic University, USA

AK

Ashok Kumar

Dr. Ashok Kumar is currently working as an Associate Professor in the Department of Biochemistry of All India Institute of Medical Sciences Bhopal. His current research interest is understanding the role of non-coding RNAs and sphingosine-1-phosphate signaling in Head and Neck Cancer. He received his PhD degree from Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS) Lucknow, India. Then, he received postdoctoral training from UCSFBenioff’s Children’s Hospital Oakland & Research Centre, Oakland, CA, USA. Dr. Ashok Kumar’s major area of research work are Cell & Molecular Biology, Cancer Biology, Immunology & Sphingolipid signaling. He has more than 15 years of research experience. He has published more than 50 research articles and 10 book chapters and he has edited two books. He is a member of several international professional societies including American Association of Cancer Research and Fellow of Royal Society of Biology
Affiliations and expertise
Associate Professor, Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), Bhopal, MP, India

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