
Chemical Tools in Microbiology 1
- 1st Edition, Volume 664 - March 22, 2022
- Imprint: Academic Press
- Editor: Erin E. Carlson
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 1 2 2 2 - 8
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 1 1 3 0 - 6
Clinical Microbiology, Volume 664 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of top… Read more
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Clinical Microbiology, Volume 664 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics, including Synthesis of chemical probes to study bacterial adenylating enzymes, Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux, Combining informatics with ABPP to identify serine hydrolyses in bacteria, A Ligand Selection Strategy Identifies Chemical Probes Targeting the Proteases of SARS‐CoV‐2, Activity-based probes for bacterial histidine kinases, Metabolomic approaches to enzyme function and pathway discovery, Identification of bile salt hydrolase activity in gut microbiota, and much more.
Other chapters cover Multiplex fluorescence screening and identification using multiplex TMT, Customized Peptidoglycan Surfaces to Investigate Innate Immune Recognition via SPR, Site-Specific Siderocalin Binding to Ferric and Ferric-Free Enterobactin As Revealed by Mass Spectrometry, Proteomics of short-chain fatty acid probes in Salmonella, Development and application of highly sensitive labeling reagents for amino acids, and a variety of other timely topics.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in Methods in Enzymology serials
- Updated release includes the latest information on Chemical Microbiology
Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists
1. Integration of bioinformatic and chemoproteomic tools for the study of enzyme conservation in closely related bacterial species
Matthew Bogyo, Markus Lakemeyer and Laura J. Keller
2. A Ligand Selection Strategy to Customize Small Molecule Probes for Activity-Based Protein Profiling (LS-ABPP)
Thomas Boettcher, Philipp Schmid and Lilian Peñalver
3. Activity-based probes for bacterial histidine kinases
Erin Carlson
4. BSH-TRAP: Bile salt hydrolase tagging and retrieval with activity-based probes
Pamela Chang and Bibudha Parasar
5. Detecting and Identifying Glycoside Hydrolases Using Cyclophellitol-Derived Activity-Based Probes
Gideon Davies
6. Chemical proteomics for identifying short-chain fatty acid modified proteins in Salmonella
Howard Hang, Xinglin Yang and Zhenrun Zhang
7. Kinetic dissection of macromolecular complex formation with minimally-perturbing fluorescent probes
Rahul M. Kohli
8. Mobilization of Cryptic Antibiotic Biosynthesis Loci from Human-Pathogenic Nocardia
Sacha James Pidot and Marion Herisse
9. Endogenous Enzymes Enable Antimicrobial Activity
Ronald T. Raines and Kenton J. Hetrick
10. Identification of terpene synthases in higher fungi: combining analytical and bioinformatic methods
Martin Ruehl and Axel Orban
11. Bile salt hydrolase profiling by fluorogenic probes in the human gut microbiome
Agne Sveistyte, Carson J. Miller, Kristoffer R. Brandvold and Aaron T. Wright
12. Optimized APEX2 peroxidase-mediated proximity labeling in fast- and slow-growing mycobacteria
Jessica Seeliger
- Edition: 1
- Volume: 664
- Published: March 22, 2022
- Imprint: Academic Press
- Language: English
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