Contemporary Medical Biotechnology Research for Human Health

1st Edition - February 24, 2022
Editors: Sanket Joshi, Susmita Mukherjee, Moupriya Nag
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 9 1 2 5 1 - 8
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 1 8 3 6 - 7

Contemporary Medical Biotechnology Research for Human Health discusses a range of currently available solutions required to defeat the ever-increasing human health challe… Read more

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Contemporary Medical Biotechnology Research for Human Health discusses a range of currently available solutions required to defeat the ever-increasing human health challenges. The junction between biotechnology and biomedical/health sciences has led to several improvements in patients’ treatment, diagnosis and well-being. The book discusses vital topics ranging from biofilms and UTI, mycobacterial infections, diabetes, aplastic anemia, oral cancer, and possible applications of nanoparticles. In addition, it discusses computer-aided drug design using natural products and new technologies to develop antibiotics. This is a valuable resource for biotechnology and biomedical researchers, bioinformaticians and members of health sciences interested in understanding recent technological developments.

Cover Image
Advances in Biotechnology and Bioengineering Series
Title Page
Copyright
Dedication
Table of Contents
Contributors
Preface
Chapter 1 Human granulocyte proteins constitute the major antimycobactericidal proteins and enhance the killing of mycobacteria within macrophages
Abstract
1.1 Introduction
1.2 Materials and methods
1.3 Results
1.4 Discussion
Acknowledgments
References
Chapter 2 Prevalence of PDR bacterial strains harbored with blaNDM-1 gene isolated from UTI patients
Abstract
2.1 Introduction
2.2 Materials and methods
2.3 Results and discussion
2.4 Conclusion
Ethical approval
Acknowledgment
References
Chapter 3 Biofilm formation and antibiotic susceptibility profile among bacterial strains detected in urinary tract infected patient
Abstract
3.1 Introduction
3.2 Materials and methods
3.3 Results and discussion
3.4 Conclusion
Ethical approval
Conflict of interest
Acknowledgment
References
Chapter 4 A brief study of genes vital for diabetes and their relationship
Abstract
4.1 Introduction
4.2 Objectives
4.3 Materials and methods
4.4 Results and discussion
4.5 Conclusion
Acknowledgments
References
Chapter 5 Vascular endothelial growth factor: An attractive candidate susceptibility gene for diabetic complications in type 2 diabetes mellitus patients
Abstract
5.1 Introduction
5.2 Objective
5.3 Methodology
5.4 Results
5.5 Discussion
5.6 Conclusion
Ethical approval
Funding
Conflict of interest
Acknowledgment
References
Chapter 6 Analyzing the relation between cytokine IL-2 and cytogenetic abnormalities in acquired aplastic anemia patients
Abstract
6.1 Introduction
6.2 Material and methods
6.3 Results and discussion
6.4 Conclusion
Disclosure
Acknowledgments
References
Chapter 7 A comparative study of arsenic exposure in human papilloma virus infection and oral squamous cell carcinoma—An alarming interpretation
Abstract
7.1 Introduction
7.2 Objective
7.3 Materials and methods
7.4 Results
7.5 Discussion
7.6 Conclusion
Acknowledgments
References
Chapter 8 Correlation between oral cancer and betel quid: A molecular cytogenetics study
Abstract
8.1 Introduction
8.2 Materials and methods
8.3 Results and discussions
8.4 Conclusion
References
Chapter 9 Trolox assisted inhibition of glutamate excitotoxicity-mediated degeneration in retina
Abstract
9.1 Introduction
9.2 Materials and method
9.3 Results and discussion
9.4 Conclusion
Conflict of interest
References
Chapter 10 Therapeutic and nodulation properties of cross-talking (iso) flavonoids
Abstract
10.1 Introduction
10.2 Computational details
10.3 Results and discussion
10.4 Conclusion
Acknowledgment
References
Chapter 11 Efficacy of green synthesized silver nanoparticles (AgNP) over crude plant extract of Allium cepa and standard antibiotic against bacterial biofilms
Abstract
11.1 Introduction
11.2 Materials and methods
11.3 Results and discussions
11.4 Conclusion
References
Chapter 12 Effectiveness of onion (Allium cepa L.) skin in human health
Abstract
12.1 Introduction
12.2 Materials and methods
12.3 Results and discussion
12.4 Conclusion
References
Chapter 13 Application of random forest in detection of Parkinson's disease
Abstract
13.1 Introduction
13.2 Proposed method
13.3 Experimental setup
13.4 Data description
13.5 Results and discussion
13.6 Conclusion
References
Chapter 14 Computer-aided drug design of lead compounds against dopamine and metabotropic glutamate receptors (metabotropic glutamate receptors 1)
Abstract
14.1 Introduction
14.2 Aims and Objectives
14.3 Methodology
14.4 Results and discussion
14.5 Discussion
14.6 Conclusion
References
Chapter 15 Brain tissue segmentation using modified fuzzy C-means clustering
Abstract
15.1 Introduction
15.2 Preliminaries
15.3 Proposed methodology—MFCM (modified fuzzy C-means algorithm)
15.4 Experimental results and discussion
15.5 Conclusion
References
Chapter 16 Tumor detection using spatial hybrid clustering (SHCM) from brain MRI scans
Abstract
16.1 Introduction
16.2 Preliminaries
16.3 Proposed methodology
16.4 Experimental results and discussion
16.5 Conclusion
References
Chapter 17 Identification of potential drug targets by detangling protein–protein interaction network
Abstract
17.1 Introduction
17.2 Related terminologies
17.3 Dataset
17.4 Methodology
17.5 Results and discussions
Funding
Acknowledgments
References
Chapter 18 Molecular docking studies between components of eucalyptus essential oil and homologically modeled target protein
Abstract
18.1 Introduction
18.2 Materials, methods, and softwares
18.3 Results and discussion
Acknowledgment
References
Chapter 19 Cryopreservation of mesenchymal stem cells (MSCs) derived from bone marrow with carbohydrate additive sucrose and dimethyl sulfoxide (DMSO)
Abstract
19.1 Introduction
19.2 Materials and methods
19.3 Results
19.4 Discussion
19.5 Conclusion
Acknowledgments
References
Chapter 20 Behavioral difference of interactions between photosensitizer MC 540 and serum albumins in anionic AOT and cationic CTAB reverse micelles
Abstract
20.1 Introduction
20.2 Material and methods
20.3 Results and discussion
20.4 Conclusion
Acknowledgments
References
Chapter 21 Mobile health monitoring for senior citizens using femtolet-based fog network
Abstract
21.1 Introduction
21.2 Proposed M-health monitoring model
21.3 Latency and power consumption in m-HF2N
21.4 Performance analysis of m-HF2N
21.5 Conclusion
References
Chapter 22 Analytical study on variation of healthcare status in Haldia city of West Bengal, India
Abstract
22.1 Introduction
22.2 Methods
22.3 Results and discussion
22.4 Conclusions
Acknowledgments
References
Index

Sanket Joshi

Dr. Sanket Joshi is currently a Professor at the Amity Institute of Microbial Technology, Amity University, Rajasthan, India. He has academic teaching and research experience of about 16 years, and industrial R&D experience of about 4 years in India and Oman. While working in Indian pharma companies, he undertook several turnkey projects. His current research interests encompass energy (In-situ/ex-situ microbial enhanced light/heavy oil recovery; chemical enhanced oil Recovery; biofuels), microbial products (biosurfactants, biopolymers, R&D and scale-up), and environmental bioremediation (crude oil pollution; analysis, mitigation and control of souring by Sulfate reducing bacteria; HPAM contaminated sites). He has about 125 scientific publications in international journals, book chapters, and conference proceedings, and two books to his credit. He is an Academic/Associate Editor for: Frontiers in Microbiology, PeerJ, Ecotoxicology (Springer), Petroleum Science and Technology (Springer), Biotech (Springer), and Open Biotechnology Journal; guest editor for Frontiers in Microbiology, Sustainability, Scientifica, and Open Biotechnology Journal.

Affiliations and expertise

Professor, Amity Institute of Microbial Technology, Amity University, Rajasthan, India

Susmita Mukherjee

Susmita Mukherjee, PhD did her Graduation and Post-graduation in Zoology. Passionate to learn and work on Environmental Biotechnology, she has been working in this field for more than 10 years towards preservation of ecosystems. She has done extensive work on the effect of ecological factors on sewage fed fisheries of East Kolkata Wetlands, India. Her doctoral work was on the Wastewater management of Kolkata city. Her research interest is in environmental toxicology and waste bioremediation primarily of land and aquatic systems. Also worked on the algal bioremediation of wastewater, understanding the effectiveness of the algal system involving different variations compared to other prevailing indigenous systems towards better management of wastewater problem.

Affiliations and expertise

Professor and Head of the Department of Biotechnology, University of Engineering and Management, India

Moupriya Nag

Moupriya Nag, PhD postdoctoral work was focused on exploring the aggregation kinetics and mechanism of action of peptides associated with neurodegenerative diseases in presence of various membrane surfaces with solution NMR, making her gain experience with various state of the art techniques used in a molecular biology research.  Her research interests include single molecule biophysics of protein unfolding/refolding and protein aggregation kinetics and its mechanism of action, especially the amyloid proteins in neurodegenerative disorders. Recently, her research focuses on functional amyloids in bacteria and their relation in forming biofilms. She has about 5 years of teaching experience in Biophysics, Bioinformatics, Bioprocess and Biotechnology, Enzyme Technology, Computing, Molecular Modeling and Drug Design. She has also published many research articles in the peer-reviewed international journal and authored or co-authored numerous book chapters. She is also a member of many scientific societies like Indian Biophysical Society and Indian Science Congress Association

Affiliations and expertise

Assistant Professor, Department of Biotechnology, University of Engineering and Management, India

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health

Contemporary Medical Biotechnology Research for Human Health

Purchase options

Institutional subscription on ScienceDirect

Sanket Joshi

Susmita Mukherjee

Moupriya Nag