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Elsevier

Books in Life sciences

  • Clinical Ophthalmic Genetics and Genomics

    • 1st Edition
    • Graeme C.M. Black + 2 more
    • English
    Clinical Ophthalmic Genetics and Genomics provides an accessible, clinically-focused reference for the evolving field of Genetic Ophthalmology. This well-organised, easy-to-read textbook integrates key concepts with clinical practice and is designed to enhance effective learning and retention of complex material. It includes contributions from recognised leaders in the field and provides expert guidance on the complete spectrum of genetic ophthalmic disorders.

  • Current Topics in iPSCs Technology

    • 1st Edition
    • Volume 17
    • Alexander Birbrair
    • English
    Current Topics in iPSCs provides a deep analysis of the underlying fundamentals that support short and mid-term developments and milestones in the business of mesenchymal stem cell therapies. This volume explores the next frontier of MSC therapies and how the transformational potential of therapeutic adult cells will be realised in all therapy areas. The impacts of clinical and economic benefits are dissected throughout each of the chapters. Written by thought leaders in the field for those curious about the interface of science and business.

  • Modeling Electrochemical Dynamics and Signaling Mechanisms in Excitable Cells with Pathological Case Studies

    • 1st Edition
    • Tetsuya Watanabe
    • English
    Modeling Electrochemical Dynamics and Signaling Mechanisms in Excitable Cells with Pathological Case Studies covers the neuronal cell communication system in excitable cells, recognizing the most relevant mechanisms of cell communication. Along with new findings in biotechnology, medicine and pathological cases for clinicians, the book highlights electrochemical potential in living nerve and muscle cells. Written for physiological scientists, pharmaceutical scientists, medical doctors, biologists and physicists, this book an essential read for a real understanding of the signals as we see them.

  • Innovative Data Integration and Conceptual Space Modeling for COVID, Cancer, and Cardiac Care

    • 1st Edition
    • Amy Neustein + 1 more
    • English
    In recent years, scientific research and translation medicine have placed increased emphasis on computational methodology and data curation across many disciplines, both to advance underlying science and to instantiate precision-medicine protocols in the lab and in clinical practice. The nexus of concerns related to oncology, cardiology, and virology (SARS-CoV-2) presents a fortuitous context within which to examine the theory and practice of biomedical data curation. Innovative Data Integration and Conceptual Space Modeling for COVID, Cancer, and Cardiac Care argues that a well-rounded approach to data modeling should optimally embrace multiple perspectives inasmuch as data-modeling is neither a purely formal nor a purely conceptual discipline, but rather a hybrid of both. On the one hand, data models are designed for use by computer software components, and are, consequently, constrained by the mechanistic demands of software environments; data modeling strategies must accept the formal rigors imposed by unambiguous data-sharing and query-evaluation logic. In particular, data models are not well-suited for software-level deployment if such models do not translate seamlessly to clear strategies for querying data and ensuring data integrity as information is moved across multiple points. On the other hand, data modeling is, likewise, constrained by human conceptual tendencies, because the information which is managed by databases and data networks is ultimately intended to be visualized/utilized by humans as the end-user. Thus, at the intersection of both formal and humanistic methodology, data modeling takes on elements of both logico-mathematical frameworks (e.g., type systems and graph theory) and conceptual/philosoph... paradigms (e.g., linguistics and cognitive science). The authors embrace this two-sided aspect of data models by seeking non-reductionistic points of convergence between formal and humanistic/conceptua... viewpoints, and by leveraging biomedical contexts (viz., COVID, Cancer, and Cardiac Care) so as to provide motivating examples and case-studies in this volume.

  • Advances in Dairy Microbial Products

    • 1st Edition
    • Joginder Singh Panwar + 1 more
    • English
    Advances in Dairy Microbial Products describes the importance and utility of microbial products used in dairy products. This book explains the makeup of these products in a scientifically sound yet simple manner. The appeal of this book is its holistic approach to addressing the different aspects of the dairy industry, from basic dairy microbial biochemistry to production of dairy products and their nutrient quality, and finally to machine learning applications in dairy industry. Comprised of chapters written and edited by international authorities and researchers with top expertise in dairy products, it offers both established and cutting-edge solutions to the numerous challenges commonly encountered in the industrial processing of milk and the production of milk products. This book offers a highly practical approach to the topic, addressing and tackling the problems faced in the workplace by dairy technologists. Researchers and practitioners will find this book to be an ideal source of thorough and up-to-date information on dairy microbial products while also appealing to beginners seeking to understand how advanced dairy technologies can increase the efficiency of current techniques.

  • Chronic Obstructive Pulmonary Disease (COPD) Diagnosis using Electromyography (EMG)

    • 1st Edition
    • Archana Bajirao Kanwade + 1 more
    • English
    Chronic Obstructive Pulmonary Disease (COPD) Diagnosis using Electromyography (EMG) presents a new and innovative method of COPD diagnosis using EMG to analyze sternomastoid muscle activity using features extraction and classification. The book describes the methodology of EMG analysis, the slope-based onset detection algorithm and SEMG analysis in time, frequency and time frequency domain analyses. It also explores the identification of frequencies for single frequency Continuous Wavelet Transform (CWT) analysis and feature extraction and selection for successful classification COPD into its severity grades. The book provides a compilation of all techniques used in the literatures and emphasizes newly proposed techniques for the early detection of COPD. Fully comprehensive, the book includes discussion of limitations of existing methods for COPD diagnosis and introduces new efficient methods for COPD identification, classification and early diagnosis.

  • Biomarkers in Bipolar Disorders

    • 1st Edition
    • Rodrigo Machado-Vieira + 1 more
    • English
    Biomarkers in Bipolar Disorders summarizes cutting-edge findings in biomarkers' research, emphasizing the most promising findings, tools and technologies relevant to drug development and personalized medicine. Key findings cover different levels of evidence such as genes, molecules, cells, systems, brain and behavior related to diagnosis (state and trait/endophenotypes... prediction of treatment response and follow-up outcomes, along with the most promising perspectives in each area. Each section includes a comprehensive and focused overview on the state-of-the-art and perspectives. The book concludes with a section on practical applications, encompassing diagnostics development (genetic testing, biomarkers), and new drug development. Edited by Dr. Rodrigo Machado-Vieira and Dr. Jair C. Soares, and contributed by leading experts in the field of biomarker research, this book will be become the leading tool for all researchers and clinicians in Bipolar Disorder.

  • Antiangiogenic Drugs as Chemosensitizers in Cancer Therapy

    • 1st Edition
    • Volume 18
    • English
    Anti-angiogenic Drugs as Chemosensitizers in Cancer Therapy, Volume 19 focuses on the use of anti-angiogenic drugs as sensitizers of tumor cells to the inhibitory activity of antitumor agents. Conventional and novel anti-neoplastic agents (cytotoxic molecules, hormones/antihormone... immunotherapies) are taken into consideration, along with advances made in combination therapies. The book encompasses examples of studies on the use of antiangiogenic compounds—molecules that inhibit the growth of vessels inside a tumor—together with antineoplastic drugs in order to sensitize the resistant tumor to their cytotoxic effects, thus reducing adverse side reactions and resistance and improving the therapeutic response of cancer patients. In addition, the book discusses clinical applications in various types of cancer, such as colorectal, lung, breast, renal, genitourinary, skin and brain and circulating tumors. It is a valuable resource for cancer researchers, clinicians and members of the biomedical field who wants to be up-to-date on the most recent and promising developments in the field.

  • Advances in Protein Molecular and Structural Biology Methods

    • 1st Edition
    • Timir Tripathi + 1 more
    • English
    Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application.

  • Neuroplasticity

    From Bench to Bedside
    • 1st Edition
    • Volume 184
    • Angelo Quartarone + 2 more
    • English
    Neuroplasticity: From Bench to Bedside, Volume 184 in the Handbook of Clinical Neurology series, provides a comprehensive multidisciplinary guide to neuroplasticity. Sections summarize the basic mechanisms of neuroplasticity, focus on neuroplasticity in movement disorders, discuss brain oscillations in neurological disorders, segue into plasticity in neurorehabilitation, and cover issues of inflammation and autoimmunity in neuroplasticity. The book concludes with a section on neuroplasticity and psychiatric disorders.

  • Formulation and Device Lifecycle Management of Biotherapeutics

    A Guidance for Researchers and Drug Developers
    • 1st Edition
    • Beate Bittner + 1 more
    • English
    Today, the pressure on healthcare costs and resources is increasing, and especially for biopharmaceuticals that require parenteral administration, the inherent complex and invasive dosing procedure adds to the demand for efficient medical management. In light of the COVID-19 pandemic the value of drug delivery technologies in enabling a flexible care setting is broadly recognized. In such a setting, patients and their caregivers can choose the place of drug administration based on individual preferences and capabilities. This includes not only dosing in the clinic but also supervised at-home dosing and self-administration for eligible patients. Formulation and Device Lifecycle Management of Biotherapeutics: A Guidance for Researchers and Drug Developers covers the various aspects of improving drug delivery of biological medicines with the ultimate goal to reduce dosing complexity associated with parenteral administration and, thus, enhance patient experience and drug administration-relat... healthcare capacity. The target audience are multidisciplinary researchers and drug developers in the pharmaceutical industry, biotech companies, and academia involved in formulation and device development. This includes pharmacology and medical experts in charge of generating nonclinical and clinical data to support approval of novel dosing regimens, and drug delivery scientists and engineers responsible for technical particulars of product optimizations. Moreover, professionals in market access and commercial functions are expected to benefit from the discussions about the impact of patient and healthcare provider needs and country-specific reimbursement models on realizing a truly convenient and cost and resource efficient drug delivery solution.

  • Hormones

    • 4th Edition
    • Gerald Litwack
    • English
    Hormones, Fourth Edition provides a report on the field of human hormones viewed in light of our current understanding of cellular and subcellular architecture, along with the molecular details of their modes of action. Comprehensive information about hormone action on canonical and non-canonical signaling pathways at cellular and subcellular level and effects on architecture and function of organ systems are discussed. All chapters in this new edition have been completely updated to cover advances in endocrinology research, which has expanded significantly in the last few years. Vast coverage of hormones not previously covered and newly discovered aspects of hormone action are also included. This new fourth edition is intended to be used by advanced undergraduates and graduate students in the biological sciences. It will also provide useful background information for health professionals, clinicians and researchers in the field of endocrinology, metabolism and biochemistry.

  • Advances in Agronomy

    • 1st Edition
    • Volume 171
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 171, the latest release in this leading reference, contains a variety of updates and new advances in the field, including updates on Elevated CO2 in Semi-arid Cropping Systems: A Synthesis of Research from the Australian Grains Free Air CO2 Enrichment (AGFACE) Research Program, Simultaneous Effects of Legume Cultivation on Carbon and Nitrogen Accumulation in Soil, Growing Small Grains Organically in the Semiarid West: A Review of Markets and Management Practices to Optimize Productivity and Sustainability, Principles and Applications of Topography in Precision Agriculture, Retention of Heavy Metals by Dredged Sediments and their Management Following Land Application, and more. Other chapters focus on Genetic Diversity for Developing Climate-resilient Wheats to Achieve Food Security Goals and A Century of Subclover: Lessons for Sustainable Intensification from a Historical Review of Innovations in Subterranean Clover Seed Production.

  • Understanding Cancer

    From Basics to Therapeutics
    • 1st Edition
    • Buddhi Prakash Jain + 1 more
    • English
    Understanding Cancer: From Basics to Therapeutics presents both basic concepts and research prospects in the field of cancer biology. This book summarizes the fundamental aspects of cancer and presents a detailed description of molecular aspects as well as treatment and therapeutics for patients. The book is divided into three parts: the first part deals with the basics of cancer, including etiology and medical diagnosis; the second part explores the molecular mechanisms associated with cancer, focusing on cell cycle and apoptosis, cell metabolism, gene regulation, epigenetics, and stem cells; and the third part is dedicated to therapeutics, discussing chemo and radiotherapies, gene, hormone, herbal, and immunotherapies. It is a valuable resource for cancer researchers, oncologists, graduate students, and biomedical researchers who need to understand the fundamental topics related to cancer to apply to their research work or clinical setting.

  • Membrane Proteins

    • 1st Edition
    • Volume 128
    • Rossen Donev
    • English
    Membrane Proteins, Volume 128 in the Advances in Protein Chemistry and Structural Biology series highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications - Part A

    • 1st Edition
    • Volume 186
    • English
    Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications, Volume 185, Part A represents the collation of chapters written by eminent scientists worldwide. Chapters in this updated release include An introduction to microfluidics and their applications, Design and fabrication of Micro/Nanofluidics devices and systems, Detection and separation of proteins using Micro/Nanofluidics devices, Micro/Nanofluidics devices for DNA/RNA detection and separation, Paper based microfluidics a forecast towards the most affordable and rapid point-of-care devices, Paper based micro/Nanofluidics devices for biomedical applications, Advances of Microfluidics Devices and their Applications in Personalized Medicine, and much more. Additional chapters cover Microfluidics for single cell analysis, Fluorescence Based Miniaturized Microfluidic and Nanofluidic Systems for Biomedical Applications, Active Matter Dynamics in Confined Microfluidic Environments, Challenges and opportunities in micro/nanofluidics and lab-on-a-chip, and Paper-microfluidic signal-enhanced immunoassays.

  • Tamoxifen Tales

    Suggestions for Scientific Survival
    • 1st Edition
    • V. Craig Jordan
    • English
    Tamoxifen Tales: Suggestions for Scientific Survival presents a case study describing the academic journey of teams behind major advances in medical sciences, highlighting lessons learned that are applicable to the next generation of scientists. This book provides a manual on the successful mentoring of young scientists, including stories describing how training experience shaped careers to become leaders in academia and the pharmaceutical industry. The book documents Professor V. Craig Jordan’s 50-year career in medical sciences that led to the discovery and development of Selective Estrogen Receptor Modulators (SERMs), which became the standard of women’s healthcare around the world. Additionally, it illustrates the versatility of a scientist with a commitment to serving societies. This important resource will be a useful and interesting book for established medical scientists, research mentors and advanced students wanting to chart a successful and impactful research career.

  • New Frontiers and Applications of Synthetic Biology

    • 1st Edition
    • Vijai Singh
    • English
    New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more. This book is a good source for not only researchers in designing synthetic biology, but also for researchers, students, synthetic biologists, metabolic engineers, genome engineers, clinicians, industrialists, stakeholders and policymakers interested in harnessing the potential of synthetic biology in many areas.

  • Agriculture's Ethical Horizon

    • 3rd Edition
    • Robert L Zimdahl
    • English
    Agriculture’s Ethical Horizon: Third Edition covers the changing environment in which practitioners of agriculture are challenged to produce food for the world. Fully revised and updated, the book encourages discussions on the moral questions that agriculture faces, including what goals should agricultural science pursue and how should practitioners address important ethical questions which are different and more complex than the dominating questions of production? The book presents the story of agriculture from the blood, sweat and tears era, to the present genetic era, including the paradox of agriculture. This book is ideal for agricultural students, practitioners and anyone who would like to understand the tremendous responsibility of agricultural production. It presents a foundation for the important discussions and decisions that will be necessary to support the future of agriculture.

  • Photosynthesis in Action

    Harvesting Light, Generating Electrons, Fixing Carbon
    • 1st Edition
    • Alexander Ruban + 2 more
    • English
    Photosynthesis in Action examines the molecular mechanisms, adaptations and improvements of photosynthesis. With a strong focus on the latest research and advances, the book also analyzes the impact the process has on the biosphere and the effect of global climate change. Fundamental topics such as harvesting light, the transport of electronics and fixing carbon are discussed. The book also reviews the latest research on how abiotic stresses affect these key processes as well as how to improve each of them. This title explains how the process is flexible in adaptations and how it can be engineered to be made more effective. End users will be able to see the significance and potential of the processes of photosynthesis. Edited by renowned experts with leading contributors, this is an essential read for students and researchers interested in photosynthesis, plant science, plant physiology and climate change.

  • Biology of Cardiovascular and Metabolic Diseases

    • 1st Edition
    • Chaya Gopalan + 1 more
    • English
    Biology of Cardiovascular and Metabolic Diseases combines physiology and pathophysiology of selected metabolic and cardiovascular diseases with health relevance. Written in a concise and easy to read manner, the book allows readers to gain an understanding on a number of topics, including cardiovascular physiology and pathophysiology and how it relates to the development of insulin resistance, diabetes and other metabolic diseases. The book also highlights the relevance of obesity in the development of cardiovascular and metabolic diseases and emphasizes the benefits of exercise as a preventative measure and way to treat underlying conditions.

  • Great American Diseases

    Their Effects on the course of North American History
    • 1st Edition
    • Ian R. Tizard + 1 more
    • English
    Great American Diseases: Their Effects on the Course of North American History presents medical history as it pertains to the major infectious diseases of North America. The book is designed to provide an interesting and engaging introduction to microbiology, immunology and epidemiology. With the advent of COVID-19, this book will serve as a reference on the history of previous epidemics. The book presents pandemics in an easy-to-read volume and provides concise chapters on the history of a disease, progression of understanding on the pathogen (agent of the disease), and their social ramifications through the history of North America.

  • iPSCs - State of the Science

    • 1st Edition
    • Alexander Birbrair
    • English
    iPSCs - State of the Science, Volume Sixteen, the latest release in the Advances in Stem Cell Biology series, is an expansive collection of information and new discoveries in the field. This volume addresses the importance of induced pluripotent stems cells and how can they be derived from different sources. It addresses advances in research in induced pluripotent stem cells from alternate sources, such as spermatogonial stem cells, ovarian tissue, cancer cells, and many other sources. It is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors.

  • Novel Concepts in iPSC Disease Modeling

    • 1st Edition
    • Volume 15
    • Alexander Birbrair
    • English
    The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs - Novel Concepts, Volume 15 addresses how important induced pluripotent stems cells are and how can they can help treat certain diseases. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different disorders, such as liver disease, type-1 diabetes, Parkinson’s disease, macular degeneration of the retina and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field.

  • Body, Brain, Behavior

    Three Views and a Conversation
    • 1st Edition
    • Tamas L. Horvath + 2 more
    • English
    Body, Brain, Behavior: Three Views and a Conversation describes brain research on the frontiers, with a particular emphasis on the relationship between the brain　and its development and evolution, peripheral organs, and other brains in communication. The book expands current views of neuroscience by illustrating the integration of these disciplines. By using a novel method of conversations between 3 scientists of different disciplines, cellular, endocrine, developmental, and social processes are seamlessly woven into topics that relate to　contemporary　livi... in health and disease. This book is a critical read for anyone who wants to become familiar with the inner workings of the nervous system and its intimate connections to the universe of contemporary life issues.

  • Deep Learning in Bioinformatics

    Techniques and Applications in Practice
    • 1st Edition
    • Habib Izadkhah
    • English
    Deep Learning in Bioinformatics: Techniques and Applications in Practice introduces the topic in an easy-to-understand way, exploring how it can be utilized for addressing important problems in bioinformatics, including drug discovery, de novo molecular design, sequence analysis, protein structure prediction, gene expression regulation, protein classification, biomedical image processing and diagnosis, biomolecule interaction prediction, and in systems biology. The book also presents theoretical and practical successes of deep learning in bioinformatics, pointing out problems and suggesting future research directions. Dr. Izadkhah provides valuable insights and will help researchers use deep learning techniques in their biological and bioinformatics studies.

  • Food Systems Modelling

    Tools for Assessing Sustainability in Food and Agriculture
    • 1st Edition
    • Christian J. Peters + 1 more
    • English
    Food Systems Modelling emphasizes sustainability, including the impact of agriculture and food production on profits, people and environment, with a particular focus on the ability of humanity to continue producing food in the midst of global environmental change. Sections introduce the purpose of models, the definition of a food system, the importance of disciplinary, interdisciplinary, and transdisciplinary inquiry, cover specific branches of modeling in the sustainability of food systems, and wrestle with the challenge of communicating modeling research and appropriately integrating multiple dimensions of sustainability. This book will be a welcomed reference for food scientists, agricultural scientists, nutritionists, environmental scientists, ecologists, economists, those working in agribusiness and food supply chain management, community and public health, and urban and regional planning, as well as academicians and graduate students interested in the sustainability of food systems.

  • Comprehensive Gut Microbiota

    • 1st Edition
    • Maria Glibetic
    • English
    Comprehensive Gut Microbiota, Three Volume Set provides new insights into gut microbiota as a critical mediator of human health and well-being. Comprehensive chapters, split across three volumes, present trusted and authoritative sources of information for novel human gut microbiome and health research. The book focuses on the fascinating intestinal microbiome and its interaction with food, food bioactive components, nutrition and human health. Chapters address the core science in the microbiota field and draw links between the microbiome, food, nutrition and health interaction. The text reflects the current state of evidence available in the field of microbiota, its regulation at the individual and population level, and the importance of the microbiome to human health. Each section includes introductory chapters that present key concepts about the section objective. Later sections focus on the novel findings of the gut microbiome, food and nutrition science. Human studies and systematic literature reviews are also discussed throughout the work.

  • Translational Autoimmunity, Volume 2

    Treatment of Autoimmune Diseases
    • 1st Edition
    • Nima Rezaei
    • English
    Translational Autoimmunity: Treatment of Autoimmune Diseases, Volume Two in the Translational Immunology series, focuses on advances in therapeutic modalities in autoimmune diseases. Efficacy and safety of not only the current biologic therapies, but also novel drug targets are discussed. Therapeutic targeting of B regulatory cells, T regulatory cells, as well as the immunomodulation effects of nanoparticles and organisms are also covered, along with our understanding and future challenges of prognostic significance of treatments in autoimmune diseases.

  • Stereotaxic Brain Atlas of the Egyptian Fruit Bat

    • 1st Edition
    • Raya Eilam-Altstadter + 3 more
    • English
    The Stereotaxic Brain Atlas of the Egyptian Fruit Bat provides the first stereotaxic atlas of the brain of the Egyptian fruit bat (Rousettus aegyptiacus), an emerging model in neuroscience. This atlas contains coronal brain sections stained with cresyl violet (Nissl), AChE, and Parvalbumin – all stereotaxically calibrated. It will serve the needs of any neuroscientist who wishes to work with these bats – allowing to precisely target specific brain areas for electrophysiology, optogenetics, pharmacology, and lesioning. More broadly, this atlas will be useful to all neuroscientists working with bats, as it delineates many brain regions that were not delineated so far in any bat species. Finally, this atlas will provide a useful resource for researchers interested in comparative neuroanatomy of the mammalian brain.

  • Genesis, Pathophysiology and Management of Venous and Lymphatic Disorders

    • 1st Edition
    • N. Radhakrishnan
    • English
    Genesis, Pathophysiology Management of Venous Diseases is the must-have resource on venous disease. The book bridges the gap between basic science and clinical medicine, covering the history of venous surgery, the lymphatic system and anatomy, pathophysiology of various venous disease, etiology, clinical manifestations and diagnosis, management, and medical and surgical treatment options. It also places attention on genetic studies and pharmacological analysis of various anticoagulants which are widely used in treating venous diseases and deep vein thrombosis and highlights the importance of microscopic venous valves and their pathology in both normal and disease condition. The breadth of topics covered makes this reference suitable for a range of professionals in phlebolymphology and cardiology, including medical students, practicing clinicians, surgeons, researchers, radiologists, bioengineers, and more.

  • A New History of Vaccines for Infectious Diseases

    Immunization - Chance and Necessity
    • 1st Edition
    • Anthony R. Rees
    • English
    A New History of Vaccines for Infectious Diseases: Immunization - Chance and Necessity covers the developments of vaccines and how they have obliterated many fatal diseases and infections over time. The book treads a neutral path but does not avoid discussion. As uncertainty in the outcome of vaccination can only be determined by experiment, the path to vaccine development has been scientifically complex because the immune system and the manner in which humans respond to infection is variable and complex. Finally, the book describes the risks and benefits of vaccines in a visibly objective manner.

  • Stimuli-Responsive Nanocarriers

    Recent Advances in Tailor-Made Therapeutics
    • 1st Edition
    • Virendra Gajbhiye + 2 more
    • English
    Stimuli-Responsive Nanocarriers: Recent Advances in Tailor-Made Therapeutics compiles dispersed knowledge into a complete and comprehensive source to help researchers understand and progress stimuli-responsive nanocarriers. The book contains recent advancements made in the field of stimuli-responsive nanocarriers with their application in controlled drug delivery against various diseases. It focuses on the design, mechanism, construction, therapeutic application and future challenges of stimuli-responsive nanocarriers which will help new researchers in designing next generation tailor-made advanced therapeutics. Finally, the book covers future aspects and challenges present in the route of development of stimuli responsive nanocarriers for disease therapeutics. Various recent advances and biomedical applications assembled in this book will guide scientists on how to design and develop novel controlled drug release systems.

  • Adrenal Disorders

    100 Cases from the Adrenal Clinic
    • 1st Edition
    • William F. Young + 1 more
    • English
    Adrenal disorders are often difficult to diagnose due to common symptoms, and challenging to treat due to common comorbidities. Adrenal Disorders: 100 Cases from the Adrenal Clinic provides a comprehensive, case-based approach to the evaluation and treatment of both common and uncommon adrenal disorders, offering practical, real-world guidance highlighted by detailed laboratory evaluations, computed cross sectional images, nuclear medicine images, and gross pathology photographs.

  • The Mammalian Spinal Cord

    • 1st Edition
    • Charles Watson + 2 more
    • English
    The Mammalian Spinal Cord provides a comprehensive account of the anatomy and histology of the spinal cord. The text covers the cytoarchitecture, chemoarchitecture, motor neuron distribution, long tracts, autonomic outflow, and gene expression in the spinal cord. A feature of the book is the inclusion of segment-by-segment atlases of the spinal cords of rat, mouse, newborn mouse, marmoset, rhesus monkey, and human. This book is an essential reference for researchers studying the spinal cord.

  • Microbiological Analysis of Foods and Food Processing Environments

    • 1st Edition
    • Osman Erkmen
    • English
    Microbiological Analysis of Foods and Food Processing Environments is a well-rounded text that focuses on food microbiology laboratory applications. The book provides detailed steps and effective visual representations with microbial morphology that are designed to be easily understood. Sections discuss the importance of the characteristics of microorganisms in isolation and enumeration of microorganisms. Users will learn more about the characteristics of microorganisms in medicine, the food industry, analysis laboratories, the protection of foods against microbial hazards, and the problems and solutions in medicine and the food industry. Food safety, applications of food standards, and identification of microorganisms in a variety of environments depend on the awareness of microorganisms in their sources, making this book useful for many industry professionals.

  • Comparative Veterinary Anatomy

    A Clinical Approach
    • 1st Edition
    • James A. Orsini + 2 more
    • English
    Comparative Veterinary Anatomy: A Clinical Approach describes the comprehensive, clinical application of anatomy for veterinarians, veterinary students, allied health professionals and undergraduate students majoring in biology and zoology. The book covers the applied anatomy of dogs, cats, horses, cows and other farm animals, with a short section on avian/exotics, with a focus on specific clinical anatomical topics. The work improves the understanding of basic veterinary anatomy by making it relevant in the context of common clinical problems. This book will serve as a single-source reference on the application of important anatomical structures in a clinical setting. Students, practitioners and specialists will find this information easy-to-use and well-illustrated, thus presenting an accurate representation of essential anatomical structures that relates to real-life clinical situations in veterinary medicine.

  • Advances in Animal Experimentation and Modeling

    Understanding Life Phenomena
    • 1st Edition
    • Ranbir Chander Sobti
    • English
    Exploration in Laboratory Animal Sciences Understanding Life Phenomena updates our knowledge about the newer technologies such as molecular biology, genomics including sequencing, proteomics, transcriptomics, cell culture, stem cell culture, transgenesis and their translation to understand systematics and phylogeny of laboratory animals at molecular level. In seven sections Exploration in Laboratory Animal Sciences Understanding Life Phenomena resolves issues of conservation, applications in environment monitoring, production of drugs and others. Comparative research has enabled use of domestic animal models that translate the advances in basic biosciences to the schemes for human welfare including medicine. Molecular geneticists are unravelling the complexities of mammalian genes and the field of biotechnology is maturing at a fast pace. Additionally, research focused on immunology and animal behavior offer new insight into ways of enhancing animal welfare. The rise in consumption of animal proteins in addition to the challenges of sustaining our natural resources has given animal scientists a vast array of opportunities to engage in integrative systems-based research for meeting the challenges that behold us. Exploration in Laboratory Animal Sciences Understanding Life Phenomena also discusses the manipulation of animals as factories for the production of safe foods, drugs, and sensors and others to meet the contemporary challenges faced by mankind in the new world order created by pandemic of Covid 19. It also includes several chapters on the causation and management of certain diseases and impact of microbes on life.

  • Chesley's Hypertensive Disorders in Pregnancy

    • 5th Edition
    • Robert N. Taylor + 4 more
    • English
    Leon Chesley’s Hypertensive Disorders in Pregnancy was initially published in 1978. Four decades later, hypertension complications in pregnancy are still a major cause of fetal and maternal morbidity and death, especially in less developed nations. It is also a leading cause of preterm birth now known to be a risk factor in remote cardiovascular disease. Despite this, hypertensive disorders remain marginally studied and management is often controversial. Chesley’s Hypertensive Disorders in Pregnancy, Fifth Edition continues its tradition as one of the beacons to guide the field of preeclampsia research, recognized for its uniqueness and utility. This revision focuses on prediction, prevention, and management for clinicians, and is an essential reference text for clinical and basic investigators alike. It provides a superb analysis of the multiple topics that relate to hypertension in pregnancy, especially of preeclampsia.

  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 34
    • Aleš Iglič︎ + 2 more
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 34, formerly titled Advances in Planar Lipid Bilayers and Liposomes, provides a global platform for the study of cell membranes, lipid model membranes and lipid self-assemblies, from the micro- to the nanoscale. As planar lipid bilayers are widely studied due to their ubiquity in nature, this book presents research on their application in the formulation of biomimetic model membranes, and in the design of artificial dispersion of liposomes. Chapters cover Physical properties of SOPC lipid membranes containing cholesterol by molecular dynamics simulation, Exciting membrane fluctuations - more than thermal stimulation, Fluctuations shaping bio-membrane adhesion, and more.

  • Prosopis as a Heat Tolerant Nitrogen Fixing Desert Food Legume

    Prospects for Economic Development in Arid Lands
    • 1st Edition
    • Maria Cecilia Puppo + 1 more
    • English
    Prosopis describes the enormous historical importance of these trees as a human food source and reviews the contemporary food science of the fruit derived from these trees. As well, this treatise reviews the native genetic resources of this genus on 4 continents and classical genetic and horticultural techniques that could help stabilize the environment and alleviate human suffering on some of the world’s most destitute agro-ecosystems. This book is an essential read for researchers interested in forestry and plant science, environmental science, and functional foods. The legume family (Fabaceae) contains many genera and species that through their nitrogen fixing process provide high protein food and feed for humans and animals. As evidenced by its presence in Death Valley, California, which holds the record for the highest temperatures in the world, these types of plants can thrive in extreme environments.

  • Postharvest Handling

    A Systems Approach
    • 4th Edition
    • Wojciech J. Florkowski + 3 more
    • English
    This newly revised fourth edition of Postharvest Handling brings new and updated chapters with new knowledge and applications from postharvest research. The revised edition brings back the aspects of preharvest conditions and their effects on postharvest quality and features new chapters on the increasingly important role of transportation and logistics. It emphasizes consumers and systems thinking for postharvest chains for fresh produce. This book also explores current challenges—including oversupply, waste, food safety, lack of resources, sustainability — and best practices for systems to thrive in spite of these challenges. This unique resource provides an overview of postharvest systems and their role in food value chains and offers essential tools to monitor and control the handling process.Written by a team of experts in Postharvest Systems and Handling, this book continues to be the most practical and up-to-date resource for postharvest physiologists and technologists across the disciplines of agricultural economics, agricultural engineering, food science, and horticulture along with businesses handling fresh or minimally processed products.

  • Avian Immunology

    • 3rd Edition
    • Bernd Kaspers + 3 more
    • English
    Avian Immunology, Third Edition contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers, include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. With contributions from the foremost international experts in the field, Avian Immunology 3rd, provides the most up-to-date crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. Avian Immunology, Third Edition, is a fascinating and growing field and surely provides new and exciting insights for mainstream immunology in the future.

  • The Detection of Biomarkers

    Past, Present, and the Future Prospects
    • 1st Edition
    • Sibel A. Ozkan + 2 more
    • English
    Reliable, precise and accurate detection and analysis of biomarkers remains a significant challenge for clinical　researchers... Methods for the detection of biomarkers are rather complex, requiring pre-treatment steps before analysis can take place. Moreover, comparing various biomarker assays and tracing research progress in this area systematically is a challenge for researchers. The Detection of Biomarkers presents developments in biomarker detection, including methods tools and strategies, biosensor design, materials, and applications. The book presents methods, materials and procedures that are simple, precise, sensitive, selective, fast and economical, and therefore highly practical for use in clinical research scenarios. This volume situates biomarker detection in its research context and sets out future prospects for the area. Its 20 chapters offer a comprehensive coverage of biomarkers, including progress on nanotechnology, biosensor types, synthesis, immobilization, and applications in various fields. The book also demonstrates, for students, how to synthesize and immobilize biosensors for biomarker assay. It offers researchers real alternative and innovative ways to think about the field of biomarker detection, increasing the reliability, precision and accuracy of biomarker detection.

  • Food Engineering Innovations Across the Food Supply Chain

    • 1st Edition
    • Pablo Juliano + 4 more
    • English
    Food Engineering Innovations Across the Food Supply Chain discusses the technology advances and innovations into industrial applications to improve supply chain sustainability and food security. The book captures the highlights of the 13th International Congress of Engineering ICEF13 under selected congress themes, including Sustainable Food Systems, Food Security, Advances in Food Process Engineering, Novel Food Processing Technologies, Food Process Systems Engineering and Modeling, among others. Edited by a team of distinguished researchers affiliated to CSIRO, this book is a valuable resource to all involved with the Food Industry and Academia. Feeding the world’s population with safe, nutritious and affordable foods across the globe using finite resources is a challenge. The population of the world is increasing. There are two opposed sub-populations: those who are more affluent and want to decrease their caloric intake, and those who are malnourished and require more caloric and nutritional intake. For sustainable growth, an increasingly integrated systems approach across the whole supply chain is required.

  • Future Foods

    Global Trends, Opportunities, and Sustainability Challenges
    • 1st Edition
    • Rajeev Bhat
    • English
    Future Foods: Global Trends, Opportunities, and Sustainability Challenges highlights trends and sustainability challenges along the entire agri-food supply chain. Using an interdisciplinary approach, this book addresses innovations, technological developments, state-of-the-art based research, value chain analysis, and a summary of future sustainability challenges. The book is written for food scientists, researchers, engineers, producers, and policy makers and will be a welcomed reference.

  • Reproductive Biology of the Crocodylia

    • 1st Edition
    • Valentine Lance
    • English
    Reproductive Biology of the Crocodylia is based on over 40 years of research on global crocodiles, alligators and caimans. It brings together data and information previously scattered across publications to synthesize knowledge on the history, ecology, physiology and anatomy of crocodilians. The book provides a comprehensive look at the physiology, current taxonomy, ecology and sexual maturity factors of these reptiles. It then delves into the anatomy and cycles of both male and female reproduction systems, including nesting and incubation, temperature-dependen... sex determination, and sex ratios across various species populations. Finally, the book focuses on conservation efforts to protect the reproductive cycle, taking factors such as pollution, climate change, and human disruption into consideration. It is an ideal resource for wildlife biologists and herpetologists seeking up-to-date and thorough research data on conservation efforts. It will also be helpful for exotic animal veterinarians, zookeepers, and alligator or crocodile farmers.

  • Plant Extracts: Applications in the Food Industry

    • 1st Edition
    • Shabir Ahmad Mir + 2 more
    • English
    Plant Extracts in Food Applications is the first book of its kind focusing on the application of plant extracts in the food industry. Topics cover sources, extraction and encapsulation techniques, the chemistry and stability of plant extracts, antimicrobials, preservatives, nutrient enhancers, enzymes, flavoring and coloring agents, packaging aid, health benefits, opportunities and the challenges surrounding the use of plant extracts in food applications. Written by several experts in the field, this book is a valuable resource for students, scientists, and professionals in food science, food chemistry and nutrition. Concerns and potential risks regarding the use of synthetic chemicals have renewed the interests of consumers using natural and safe alternatives. Plant extracts represent an interesting ingredient, mainly due to their natural origin and phytochemical properties, allowing for obtaining active materials to extend shelf-life and add value to the product.

  • The Composting Handbook

    A how-to and why manual for farm, municipal, institutional and commercial composters
    • 1st Edition
    • Robert Rynk + 6 more
    • English
    The Composting Handbook provides a single guide to the science, principles and best practices of composting for large-scale composting operations facing a variety of opportunities and challenges converting raw organic materials into a useful and marketable product. Composting is a well-established and increasingly important method to recycle and add value to organic by-products. Many, if not most, of the materials composting treats are discarded materials that would otherwise place a burden on communities, industries, farms and the environment. Composting converts these materials into a valuable material, compost, that regenerates soils improving soils for plant growth and environmental conservation. The Composting Handbook expands on previously available resources by incorporating new information, new subjects and new practices, drawing its content from current scientific principles, research, engineering and industry experience. In both depth and breadth, it covers the knowledge that a compost producer needs to succeed. Topics include the composting process, methods of composting, equipment, site requirements, environmental issues and impacts, business knowledge, safety, and the qualities, uses and markets for the compost products. The Composting Handbook is an invaluable reference for composting facility managers and operators, prospective managers and operators, regulators, policy makers, environmental advocates, educators, waste generators and managers and generally people interested in composting as a business or a solution. It is also appropriate as a textbook for college courses and a supplemental text for training courses about composting or organic waste management.

  • Current Advances for Development of Functional Foods Modulating Inflammation and Oxidative Stress

    • 1st Edition
    • Blanca Hernandez-Ledesma + 1 more
    • English
    Current Advances for Development of Functional Foods Modulating Inflammation and Oxidative Stress presents the nutritional and technological aspects related to the development of functional foods with anti-inflammatory and antioxidant effects. Specifically, analytical approaches for the characterization of anti-inflammatory and antioxidant properties of healthy foods and functional constituents, as well as technological strategies for the extraction of compounds and fractions from raw materials to produce anti-inflammatory and antioxidant ingredients are addressed. In addition, the molecular mechanisms by which foods and their components can modulate inflammation and their oxidative stress effects on disease prevention are explored. Finally, clinical research addressing nutritional needs in pathological subjects with inflammatory diseases are considered.

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