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Advances in Clinical Chemistry
- 1st Edition, Volume 108 - June 2, 2022
- Editor: Gregory S. Makowski
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 8 8 4 9 - 0
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 8 8 5 0 - 6
Advances in Clinical Chemistry, Volume 108, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laborator… Read more
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Request a sales quoteAdvances in Clinical Chemistry, Volume 108, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this new release focusing on Nephrinuria and podocytopathies, Extracellular vesicles in respiratory disease, Diabetes and cognitive decline, Testosterone analysis in prostate cancer, Mono/polyclonal free light chains as challenging biomarkers for immunological abnormalities, and more.
- Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science
- Authored by world renowned clinical laboratory scientists, physicians and research scientists
- Presents the international benchmark for novel analytical approaches in the clinical laboratory
Clinical Laboratory Professionals, Physicians and Research Scientists
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter One: Nephrinuria and podocytopathies
- Abstract
- 1: Introduction
- 2: Nephrin
- 3: Podocytopathies and nephrinuria
- 4: Methods for detection of nephrinuria
- 5: Diagnostic relevance of urinary nephrin in podocytopathies
- 6: Nephrin as a potential therapeutic target
- 7: Conclusions
- References
- Chapter Two: Diabetes and cognitive decline
- Abstract
- 1: Introduction
- 2: Molecular mechanisms linking metabolic impairment and cognitive decline
- 3: Predictive biomarkers of cognitive impairment in patients with type 2 diabetes mellitus
- 4: Use of CSF biomarkers for early detection of cognitive impairment in patients with type 2 diabetes mellitus
- 5: Conclusion and future perspectives
- References
- Chapter Three: Testosterone analysis in prostate cancer patients
- Abstract
- 1: Introduction
- 2: Gonadal testosterone regulation
- 3: Evolution of androgen deprivation therapy
- 4: Testosterone analysis
- 5: Automated IA vs LC–MS/MS assays
- 6: Potential clinical utility of ultra-sensitive testosterone assays
- 7: Conclusion
- References
- Chapter Four: Extracellular vesicles in respiratory disease
- Abstract
- 1: Introduction
- 2: Experimental techniques for EV research
- 3: EVs in the respiratory system
- 4: Summary and future perspective
- Acknowledgment
- References
- Chapter Five: Screening for gastrointestinal and pancreatic diseases
- Abstract
- 1: Introduction
- 2: Inflammatory diarrhea
- 3: Watery (osmotic) diarrhea
- 4: Malabsorptive diarrhea
- 5: Other stool tests for chronic conditions
- 6: Conclusion
- References
- Chapter Six: Mono/polyclonal free light chains as challenging biomarkers for immunological abnormalities
- Abstract
- 1: Background and biochemistry
- 2: Detection of FLC
- 3: FLC current clinical applications
- 4: Polyclonal FLC and clinical applications
- 5: FLC in SARS-CoV-2 infection
- 6: Conclusion
- Competing interests
- References
- Index
- No. of pages: 228
- Language: English
- Edition: 1
- Volume: 108
- Published: June 2, 2022
- Imprint: Academic Press
- Hardback ISBN: 9780323988490
- eBook ISBN: 9780323988506
GM
Gregory S. Makowski
Dr Gregory S Makowski is a board-certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President Clinical Laboratory Services Hartford HealthCare in Connecticut.
Affiliations and expertise
Vice President and Chief Scientific Officer, Clinical Laboratory Partners, Newington, CT, USA