The Role of Phytonutrients in Metabolic Disorders
- 1st Edition - June 21, 2022
- Imprint: Academic Press
- Editors: Haroon Khan, Esra Akkol, Maria Daglia
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 4 3 5 6 - 5
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 5 9 7 9 - 0
The Role of Phytonutrients in Metabolic Disorders provides the information readers need to conduct research on phytonutrients in metabolic disorders. The book presents the treatm… Read more
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Request a sales quoteThe Role of Phytonutrients in Metabolic Disorders provides the information readers need to conduct research on phytonutrients in metabolic disorders. The book presents the treatment of metabolic diseases using phytonutrients, the key regulatory mechanisms of phytonutrients in metabolic pathways, and evaluates phytonutrients as a source of new drug candidate molecules. The book compiles and evaluates the very latest findings and therapeutic developments in the management of various metabolic disorders, their underlying mechanisms, and the clinical potential and limitations of phytonutrients. Thirteen chapters illustrate the therapeutic potential of phytonutrients in the management of various metabolic disorders through the regulation of signaling pathways.
- Supports the therapeutic potential of phytonutrients in the management of metabolic disorders
- Details the regulatory mechanisms of phytonutrients in metabolic pathways
- Considers phytonutrients as a source of new drug candidate molecules
- Evaluates and compiles current research on phytonutrients in relation to metabolic disorders
- Gives insights into the clinical uses of phytonutrients for the management of metabolic disorders
Natural product researchers; nutritionists; medical practitioners; pharmacologists and pharmacognosists; food chemists; food scientists; phytochemists; medical chemistry researchers. Medical students and graduate students in pharmacology, pharmaceutical science, and related fields
- Cover
- Title page
- Table of Contents
- Copyright
- Contributors
- Section A
- Chapter 1: An overview on metabolic disorders and current therapy
- Abstract
- 1: Introduction
- 2: Origins of metabolic disease
- 3: Metabolic disorders
- 4: Present status and new trends on the treatment of metabolic disorders
- 5: Pharmacologic enzyme replacement therapy (ERT)
- 6: Conclusions
- References
- Chapter 2: Effects of phytonutrients in various metabolic pathways
- Abstract
- 1: Introduction
- 2: Significance of metabolic pathways in health and diseases
- 3: Phytonutrients
- 4: Conclusions
- References
- Chapter 3: Nanotechnology and phytonutrients
- Abstract
- 1: Introduction
- 2: Resveratrol
- 3: Emodin
- 4: Berberine
- 5: Curcumin
- 6: Quercetin
- 7: Other phytonutrients
- 8: Conclusions
- References
- Section B
- Chapter 4: Genetic effects of phytonutrients in metabolic disorders
- Abstract
- 1: Introduction
- 2: Phytonutrient-rich dietary components and genetic interactions
- 3: Phytonutrients/natural biomolecules targeting metabolic cell signaling pathways
- 4: Dietary fats involved with gene interactions in metabolic disorders
- 5: Conclusions
- References
- Chapter 5: Therapeutic role of nutraceuticals in the management of brain disorders
- Abstract
- Authors’ contribution
- 1: Introduction
- 2: Classes of neutraceuticals and their mechanisms of action
- 3: Current evidence on the use of neutraceuticals in multiple sclerosis
- 4: Amyotrophic lateral sclerosis and nutritional supplementations
- 5: Effects of neutraceuticals supplementation in Parkinson’s disease
- 6: Effects of nutraceuticals in Huntington’s disease
- 7: The role of nutraceuticals supplementation in brain ataxia
- 8: Proposed neuroprotective mechanisms of some popular nutraceuticals
- 9: Conclusions
- References
- Chapter 6: Phytonutrients in the management of glucose metabolism
- Abstract
- 1: Introduction
- 2: Diabetes mellitus
- 3: Phytonutrients and DM
- 4: Concluding remarks
- References
- Chapter 7: Phytonutrients in the management of lipids metabolism
- Abstract
- 1: Introduction
- 2: Disorders of lipid metabolism
- 3: Hypertriglyceridemia
- 4: Hypercholesterolemia
- 5: Low HDL-related abnormalities
- 6: Atherosclerosis
- 7: Obesity
- 8: Cancer
- 9: The role of phytonutrients in managing lipid-metabolism-associated disorders
- 10: Concluding remarks
- References
- Chapter 8: Cancer metabolism regulation by phytonutrients
- Abstract
- 1: Introduction
- 2: Pentose phosphate pathway (PPP)
- 3: Serine pathway
- 4: Targeting enzymes of TCA by phytonutrients
- 5: Lactic acid fermentation
- 6: Other mechanisms involved in cancer metabolism and their modulation by phytonutrients
- 7: Clinical trials
- 8: Bioavailability of phytonutrients
- 9: Synergistic effects of phytonutrients
- 10: Conclusions
- References
- Chapter 9: Acid-base and electrolyte balance regulations with phytonutrients
- Abstract
- 1: Introduction
- 2: Acid-base balance regulations
- 3: Phytonutrients
- 4: Regulation of acid-base and electrolyte balance with phytonutrients
- 5: Conclusions
- References
- Chapter 10: Therapeutic role of nutraceuticals in mitochondrial disorders
- Abstract
- 1: Introduction
- 2: Mitochondrial disorders
- 3: Therapeutic nutraceuticals
- 4: Traditional nutraceuticals
- 5: Plant-based nutraceuticals
- 6: Fruit- and vegetable-based nutraceuticals
- 7: Nutraceutical biocatalyst
- 8: Nontraditional nutraceuticals
- 9: Molecular mechanisms/targeting signaling pathway
- 10: Nutraceuticals interact with protein misfolding and endoplasmic reticulum stress pathway
- 11: Combined effects of nutraceuticals
- 12: Interaction of nutraceuticals with medicines
- 13: Regulatory challenges of nutraceuticals
- 14: Conclusions
- References
- Chapter 11: Phytonutrients in regulation of malabsorption disorders
- Abstract
- 1: Summary
- 2: Introduction
- 3: Pathophysiology of malabsorption
- 4: The role of phytonutrients in management of malabsorption-related disorders
- 5: Conclusions
- References
- Chapter 12: Skin metabolic syndrome and phytonutrients
- Abstract
- Acknowledgment
- 1: Introduction
- 2: Metabolic syndrome and skin diseases
- 3: Phytochemicals in metabolic syndrome
- 4: Conclusions
- References
- Chapter 13: Cachexia and phytonutrients
- Abstract
- 1: Introduction
- 2: Cachexia and molecular mechanisms: Targeted signaling pathways
- 3: Effect of natural products on cachexia
- 4: Conclusions
- References
- Index
- Edition: 1
- Published: June 21, 2022
- No. of pages (Paperback): 450
- No. of pages (eBook): 450
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9780128243565
- eBook ISBN: 9780323859790
HK
Haroon Khan
Prof. Dr. Haroon Khan has obtained the degree of B. Pharm (1999), M. Phil (2005), and PhD (2011) from the Department of Pharmacy, University of Peshawar. He started his career as a lecturer from the Gandhara College of Pharmacy, Gandhara University, Peshawar and currently, Professor of Pharmacy at the Department of Pharmacy, Abdul Wali Khan University Mardan, Pakistan. He has more than seventeen years of experience in pharmacy teaching, research and professional expertise in various fields of pharmaceutical sciences. Dr. Khan has 162 publications, including research, review, and editorial in various national and international reputable journals with considerable impact factor while several others are submitted or in the process of submission. His research focus is phytomedicines including phytopharmacological and phytochemical investigations of extracts/isolated compounds in collaboration with numerous national and international research groups.
The scientific contribution of Dr. Khan has been acknowledged by the Pakistan Council for Science and Pakistan Council for Science and Technology (PCST) and awarded Research Productivity four times 2011-2014. He has also published three books with LAMBERT Academic publishers, Germany and four chapters. He is also the editorial board member of various international journals. Additionally, he is supervising many post-graduate scholars in various research projects.
Affiliations and expertise
Professor, Department of Pharmacy, Abdul Wali Khan University, PakistanEA
Esra Akkol
Esra Akkol is a Professor in the Department of Pharmacognosy, Faculty of Pharmacy, at Gazi University, in Turkey.
Affiliations and expertise
Professor, Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, TurkeyMD
Maria Daglia
Maria Daglia is a Professor in the Department of Pharmacy, at the University of Naples Federico II in Naples, Italy.
Affiliations and expertise
Professor, Department of Pharmacy, University of Naples Federico II, Naples, ItalyRead The Role of Phytonutrients in Metabolic Disorders on ScienceDirect