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Elsevier

Books in Life sciences

  • Cancer Biomarkers: Clinical Aspects and Laboratory Determination

    • 1st Edition
    • Lakshmi V. Ramanathan + 2 more
    • English
    Cancer Biomarkers: Clinical Aspects and Laboratory Determination provides a comprehensive overview of current biomarkers for cancer detection, monitoring and recurrence, focusing on emerging technologies, impacts on the field, and selected biomarkers currently used in clinical practice. The content highlights current laboratory tests used in the management of adult and pediatric cancer patients. In addition, it investigates the role of Circulating Tumor Cells and circulating tumor DNA as biomarkers in cancer management as well as cytokines in monitoring response to CAR T therapies. This title is a perfect reference for clinical pathologists, laboratory scientists, medical technologists, physicians specializing in oncology, internal medicine, family practice and transplant medicine, resident physicians, medical students, nurse practitioners and clinical chemists.

  • Advances in Cardiovascular Technology

    New Devices and Concepts
    • 1st Edition
    • Jamshid Karimov + 2 more
    • English
    Advances in Cardiovascular Technology: New Devices and Concepts is a comprehensive reference for cardiovascular devices of all types. For engineers, this book provides a basic understanding of underlying pathologies and their prevalence/incidence... It also covers what devices are available, how they are clinically used, and their impact on pathophysiology. In addition, the book presents the constraints imposed on device design and manufacture by the environment in which it is used (e.g., exposure to tissues within the body, blood in particular) and the primary requirements for each specific type of device, including its durability and resistance to fatigue. For clinicians, this book contains information on primary engineering challenges, the types of devices available, their advantages and disadvantages, and the (current and emerging) tools and materials available to device designers.

  • Updates in Thyroidology, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 51-2
    • Megan R. Haymart + 1 more
    • English
    In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Megan R. Haymart and Maria Papaleontiou bring their considerable expertise to the topic of Thyroidology. Top experts in the field cover recent advances in the diagnosis and management of thyroid conditions, providing a contemporary view of updates in this challenging field.

  • Biology of Mycobacterial Lipids

    • 1st Edition
    • Zeeshan Fatima + 1 more
    • English
    Biology of Mycobacterial Lipids covers various topics pertaining to the advancements and current research in the field of mycobacterial lipids, and on the significant progress in lipidomics, in recent times. The chapters present comprehensive, yet systematic cutting-edge research, comprising mycobacterial lipid terminologies, classifications, biosynthetic pathways, tools and techniques, and functional burgeoning. This unique reference book has contributions from pioneer researchers, experts, and eminent veterans from around the globe. It covers ground-breaking work that will bridge the gap between understanding biochemical patterns related to virulence, pathogenesis, and resistance and elucidating new targets for drug design, identifying biomarkers for predicting risk, early diagnosis, and therapeutic outcome.

  • New Targets for the Treatment of Hypertension and Associated Diseases

    • 1st Edition
    • Volume 94
    • English
    New Targets for the Treatment of Hypertension and Associated Diseases, Volume 94 in the Advances in Pharmacology serial, highlights new advances in the field, with this new volume presenting interesting chapters on Cytochrome P450, 20-hydroxyeicosatetr... acid and GPR75 pathway in hypertension, Treatment of hypertension with soluble epoxide hydrolase inhibitors, Effects of allosteric modifiers of adenosine receptors in the heart, Orally active epoxyeicosatrienoic acid analogs in hypertension and renal injury, Drugs affecting the nitric oxide- cyclic GMP pathway in hypertension, Relaxin-2 and Serelaxin in renal and cardiac dysfunction in hypertension, and more.

  • New Insights on the Development of the Vascular System

    • 1st Edition
    • Domenico Ribatti
    • English
    New Insights on the Development of the Vascular System examines the most recent literature and data on the development of the vascular system, along with advice on new laboratory techniques and approaches to data analysis. This volume is a comprehensive handbook to the state-of-the-art in vascular system development. Several genetic and epigenetic mechanisms are involved in the early development of the vascular system, and there is extensive literature on the genetic background and molecular mechanisms responsible for blood vessel formation. Yet new data and techniques have been developed in recent years. Although scientific literature covers the descriptive aspects of embryonic vascular system development, modern techniques such as the technology of cell fusion, cell sorting and image analysis give new insight into the mechanisms by which vessels form and regress and how blood flow changes directions in the same vessels.

  • Food Proteomics

    Technological Advances, Current Applications and Future Perspectives
    • 1st Edition
    • Maria Lopez Pedrouso + 2 more
    • English
    Food Proteomics: Technological Advances, Current Applications and Future Perspectives addresses many of the food proteomic issues in the industry today. Food proteomics continues to be an emerging field, becoming increasingly important in product innovation, food safety, food quality and health. The book is divided into sections describing the role of proteomics in the field of food science, conceptual background methodological aspects, and bioinformatic tools employed in the field. The book describes proteomic studies collected from the most relevant animal and vegetables species in food production and discusses important food challenges from a proteomic point-of-view. This is an essential and practical reference that provides analytical tools to help introduce technical innovations in the food industry with the latest scientific information useful and accessible to new researchers in the field as well as advanced.

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 100
    • Fidel Toldra
    • English
    Advances in Food and Nutrition Research, Volume 100 provides the latest advances on emerging bioactive compounds with putative health benefits and their controlled release and application in foods and nutraceuticals, as well as up-to-date information on recent developments in food technology, including 3D printing, safety of raw materials and viruses in foods, and new low energy food processing.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 108
    • Gregory S. Makowski
    • English
    Advances in Clinical Chemistry, Volume 108, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this new release focusing on Nephrinuria and podocytopathies, Extracellular vesicles in respiratory disease, Diabetes and cognitive decline, Testosterone analysis in prostate cancer, Mono/polyclonal free light chains as challenging biomarkers for immunological abnormalities, and more.

  • Loneliness in Older Adults

    Effects, Prevention, and Treatment
    • 1st Edition
    • Luis Miguel Rondon Garcia
    • English
    Loneliness in Older Adults: Effects, Prevention, and Treatment analyzes loneliness as a complex phenomenon, taking into account the most recent contributions from neuroscience, psychology, medicine and sociology. This volume describes this phenomenon from an interdisciplinary point of view, with special emphasis on older people from a plural and heterogeneous perspective: older people in general, older immigrants, older women, older LGTBI, etc. Faced with the impact of this emerging issue, this book provides a comprehensive knowledge of loneliness, contributing scientific knowledge to the practice of evidence. Tools are also provided for professionals, providing intervention protocols with debates and proposals, and effective digital resources to combat it. Tables, images, and tools guide students, academics, and professionals step-by-step in solving the cases raised, through an integrated practice. There is no work that develops this theme from such a plural and pragmatic perspective, covering all the dimensions of loneliness in each of the thematic axes: psychological, neurological, social, and health. Readers are provided feedback for all the knowledge for a comprehensive scientific knowledge based on evidence and given the necessary instrumental skills related to being social and the functioning of our brain. This book is aimed at a very plural audience of researchers, academics and professionals in the social and behavioral sciences including psychologists, sociologists, social workers, anthropologists, and also professionals in the health sciences, among others.

  • Mitochondria as a Key Intracellular Target of Thallium Toxicity

    • 1st Edition
    • Sergey Korotkov
    • English
    Approx.264 pages

  • Mathematical Analysis of Infectious Diseases

    • 1st Edition
    • Praveen Agarwal + 2 more
    • English
    Mathematical Analysis of Infectious Diseases updates on the mathematical and epidemiological analysis of infectious diseases. Epidemic mathematical modeling and analysis is important, not only to understand disease progression, but also to provide predictions about the evolution of disease. One of the main focuses of the book is the transmission dynamics of the infectious diseases like COVID-19 and the intervention strategies. It also discusses optimal control strategies like vaccination and plasma transfusion and their potential effectiveness on infections using compartmental and mathematical models in epidemiology like SI, SIR, SICA, and SEIR. The book also covers topics like: biodynamic hypothesis and its application for the mathematical modeling of biological growth and the analysis of infectious diseases, mathematical modeling and analysis of diagnosis rate effects and prediction of viruses, data-driven graphical analysis of epidemic trends, dynamic simulation and scenario analysis of the spread of diseases, and the systematic review of the mathematical modeling of infectious disease like coronaviruses.

  • Cyanobacterial Physiology

    From Fundamentals to Biotechnology
    • 1st Edition
    • Hakuto Kageyama + 1 more
    • English
    Cyanobacteria are ancient, primordial oxygenic phototrophs, and probably the progenitor of oxygen-evolving photosynthesis. They are a prolific source of natural products and metabolites and vitally important for environmental biology and biotechnology. Cyanobacterial Physiology presents foundational knowledge alongside the most recent advances in cyanobacterial biology. The title examines the challenges of industrial application through an understanding of the basic molecular machinery of cyanobacteria. Sixteen chapters are organized into three sections. The first part covers basic cyanobacterial biology, emphasizing environmental biology such as photosynthesis, nitrogen fixation, circadian rhythm, and programmed cell death. The second part includes the chapters that discuss cyanobacterial extremophiles, adaptations, secondary metabolites, osmoprotectants, and toxins. The third part covers aspects of cyanobacterial application that are based on environmental biology. Leading scientists contribute chapters on cyanobacteria. Cyanobacterial Physiology presents a comprehensive and vibrant solution for researchers and engineers in biotechnology interested in cyanobacteria and their applications. Topics include the cyanobacterial cell and fundamental physiological processes; the biotechnological potential of cyanobacteria with their versatile metabolism; and advanced applications of cyanobacterial products. At each stage the book is informed by basic and applied research.

  • The Vascular Endothelium

    A Holistic Approach for Oncology
    • 1st Edition
    • Domenico Ribatti + 1 more
    • English
    The Vascular Endothelium: A Holistic Approach for Oncology provides novel and integrated knowledge on the endothelial cells as a crucial component involved in the growth of different organs in both physiological and pathological conditions. By covering diverse aspects of anatomy, embryology, molecular biology and pathology, it details the important role of the endothelium for the pathogenesis of cancer and how this knowledge can improve the outcome of cancer research.The content is split in six parts: appearance and evolution of the endothelial cell, which discusses for instance comparative anatomy of the endothelium in relation to the vascular system; endothelial cell in embryology and organogenesis, covering the interaction between endothelial and hematopoietic cells; the lymphatic system, which brings information on lymphatic endothelial cell markers and molecular regulation of lymphangiogenesis; the anatomy of the endothelium in adults, showing the differences in the mature endothelial cells through the body; the physiology of the endothelial cells, with organ specific physiological activity of the endothelium; and the endothelial cells in cancer, discussing the use of endothelium as target for treatment and current therapeutic approaches.This book is a valuable resource for cancer researchers, oncologists and other members of biomedical field who are interested to learn more about the complexity of vascular endothelium and its impact on cancer and other related diseases.

  • Microbial Xylanolytic Enzymes

    • 1st Edition
    • Pratima Bajpai
    • English
    Microbial Xylanolytic Enzymes describes the enzyme structure and its interaction with plant cell walls, the properties and production of different enzymes and their applications, and the knowledge gathered on the hydrolysis mechanism of hemicellulose. The knowledge gathered about the hydrolysis mechanism of the hemicelluloses, especially xylans, has greatly promoted the rapid application of these enzymes in new areas. In recent years, there has been a spurt of interest in xylan degrading enzymes due to their applications in several industrial processes, including paper and pulp industries, food and feed industries, biofuel industry, textile industry, chemical and pharmaceutical industry, brewing industry, and more. Xylan is the principal type of hemicellulose. An enzymatic complex is responsible for the hydrolysis of xylan, but the main enzymes involved are enzymes produced by fungi, bacteria, yeast, algae, protozoans, and more.

  • Feed and Feeding Practices in Aquaculture

    • 2nd Edition
    • D. Allen Davis
    • English
    Feed and Feeding Practices in Aquaculture, Second Edition continues to play an important role in the successful production of fish and other seafood for human consumption. This is an excellent resource for understanding the key properties of feeds for aquaculture, advances in feed formulation and manufacturing techniques, and the practicalities of feeding systems and strategies. Many new updates have been integrated to reflect recent advances within the market, including special emphasis on up-and-coming trends and new technologies on monitoring fish feeding patterns, making this book useful for anyone working in R&D in the production of feed, as well as nutritionists, farm owners and technicians, and academics/postgradua... students with a research interest in the area.

  • Geminivirus: Detection, Diagnosis and Management

    • 1st Edition
    • R.K. Gaur + 2 more
    • English
    Geminivirus: Detection, Diagnosis and Management focuses on the latest techniques for managing diseases caused by these circular, single-stranded (ss) DNA genomes. The most significant impact of plant diseases in host populations is often caused by emerging diseases, whose incidence in a plant host is increasing as a result of long-term changes in their underlying epidemiology. Genetic changes in pathogen and host populations, as well as changes in host ecology and environment, are major factors contributing to disease emergence. Understanding plant virus evolution is crucial for modeling the within-host and between-host dynamics and genetics of virus populations. The book presents a comprehensive review of how these viruses develop, including contributing factors such as population bottlenecks during cell-to-cell movement, systemic colonization, or between-host transmission by different procedures. Presented in five sections—Detection and Diagnosis, Emergence and Diversity, Vector and Transmission, Virus–Host Interaction, and Disease Management, the book includes host range determinant and virulence factors involved in pathogenesis, virus–vector interactions during acquisition, retention, and transmission and evaluating management strategies to control Geminivirus. The book is an essential reference for students and researchers interested in plant virology, particularly begomoviruses, geminiviruses, and vector transmission biology. Introduces identification and characterization of geminiviruses that infect agricultural crops, their wild relatives, and weed hosts Discusses recombination and reassortment mechanisms influencing viral genetic diversity, virulence, and vector transmission Explores the origin, evolution, and bottlenecks of Geminiviruses

  • Advances in Plant Tissue Culture

    Current Developments and Future Trends
    • 1st Edition
    • Avinash Chandra Rai + 3 more
    • English
    Advances in Plant Tissue Culture: Current Developments and Future Trends provides a complete and up-to-date text on all basic and applied aspects of plant tissue cultures and their latest application implications. It will be beneficial for students and early-career researchers of plant sciences and plant/agricultural biotechnology. Plant tissue culture has emerged as a sustainable way to meet the requirements of fresh produces, horticultural crops, medicinal or ornamental plants. Nowadays, plant tissue culture is an emerging filed applied in various aspects, including sustainable agriculture, plant breeding, horticulture and forestry. This book covers the latest technology, broadly applied for crop improvement, clonal propagation, Somatic hybridization Embryo rescue, Germplasm conservation, genetic conservation, or for the preservation of endangered species. However, these technologies also play a vital role in breaking seed dormancy over conventional methods of conservation.

  • Biochemistry of Drug Metabolizing Enzymes

    Trends and Challenges
    • 1st Edition
    • Muhammad Sajid Hamid Akash + 1 more
    • English
    Biochemistry of Drug Metabolizing Enzymes: Trends and Challenges is a complete and well-integrated reference on their mechanisms of action, their role in diseases, agents responsible for their deactivation, and their malfunction. Chapters explain the biochemistry of DMEs, including biochemical activation, functions, computational approaches, different contaminants on the action and function of DMEs, and describe the importance of DMEs in the drug development process. Conditions covered include metabolic diseases, cardiovascular diseases, neurological diseases, physiological diseases, xenobiotics and inflammatory responses, and their contribution in the malfunctioning of drug metabolizing enzymes. This book is the perfect resource for pharmacology and biochemistry researchers to understand the principles of DMEs. Researchers in the corporate environment will also benefit from the comprehensive list of diseases associated with malfunction of DMEs.

  • Essential Human Virology

    • 2nd Edition
    • Jennifer Louten
    • English
    *Textbook and Academic Authors Association (TAA) Textbook Excellence Award Winner, 2024*Essential Human Virology, Second Edition focuses on the structure and classification of viruses, virus transmission and virus replication strategies based upon type of viral nucleic acid. Several chapters focus on notable and recognizable viruses and the diseases caused by them, including influenza, HIV, hepatitis viruses, poliovirus, herpesviruses and emerging and dangerous viruses. Additionally, how viruses cause disease (pathogenesis) is highlighted, along with discussions on immune response to viruses, vaccines, anti-viral drugs, gene therapy, the beneficial uses of viruses, research laboratory assays and viral diagnosis assays.Fully revised and updated with new chapters on coronaviruses, nonliving infectious agents, and notable non-human viruses, the book provides students with a solid foundation in virology.

  • Environmental, Physiological and Chemical Controls of Adventitious Rooting in Cuttings

    • 1st Edition
    • Azamal Husen
    • English
    Environmental, Physiological and Chemical Controls of Adventitious Rooting in Cuttings provides a review of the environmental, physiological and chemical controls of adventitious rooting in cuttings obtained from plants. In plants, adventitious roots, which are highly useful for vegetative propagation (or clonal propagation) are produced mainly from leaves, hypocotyls, stems or shoots. Vegetative propagation may occur naturally by using propagules such as roots, underground and aerial stems, leaves, buds and bulbils. It may also be done artificially through regenerative organs (rhizomes, bulbs, and corms) and by utilizing specialized methods, like cutting, grafting and layering. This book covers the latest tactics surrounding these processes. As a plethora of factors affect the adventitious rooting of cuttings, adding to the complexity of the phenomenon. The main factors which control adventitious root formation are types of cuttings, presence of leaf area on cuttings, types of hormones and their concentration, duration of hormonal treatment (quick dip, long soak, dry dip, spray dip, or total immerse method), maturation (juvenile or mature), genotype, explant position, and more, all of which are discussed here.

  • Coenzyme B12 Enzymes Part B

    • 1st Edition
    • Volume 669
    • English
    Coenzyme B12 Enzymes, Part B, Volume 169 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on Structural characterization of cobalamin-dependent radical SAM methylases, Purification and characterization of sequential cobalamin-dependent radical SAM methylases ThnK and TokK in -lactam antibiotic biosynthesis, Characterization of the cobalamin-dependent radical S-adenosyl-L-methion... enzyme C-methyltransferase Fom3 in fosfomycin biosynthesis, Studies of OxsB and GenK, two B12-dependent radical SAM enzymes involved in natural product biosynthesis, Purification and structural elucidation of the cobalamin-dependent radical SAM enzyme OxsB, and more. Other chapters discuss Methods for studying the mechanisms of B12 enzymes, Computational investigations of B12 dependent enzymatic reactions, Using kinetic isotope effects to probe the mechanisms of adenosylcobalamin-de... enzymes, Steady-state and pre-steady state kinetic analysis of ornithine 4,5-aminomutase, and more.

  • Plant Nematode Biopesticides

    • 1st Edition
    • Anwar L. Bilgrami + 1 more
    • English
    Plant Nematode Biopesticides presents the most current knowledge on various categories of biopesticides used in the management of nematode pests of crops or those that have significant potential as biological control agents. This book presents an exploratory and investigatory compilation and explanation of the actions and potentials of predatory nematodes, microbial agents, plant and other organic products, nanobiopesticides, and predatory invertebrates as biopesticides of nematode pests of agricultural crops. It is of unique importance and value as the only currently available single-volume resource focusing on plant parasitic nematodes as the pests and biopesticides. In addition, the book addresses common reservations in using biopesticides, either alone or in integrated pest management programs, providing advanced insights on various biopesticidal agents and products. Biopesticides may be microbial (nematodes, bacteria, fungi, virus, herbs etc.), plant-incorporated protectants (PIPs), plant products (citronella oil, neem oil, capsaicin, pyrethrin etc.), synthetic biochemical molecules, pheromones, semio-chemicals, plant extracts, or nanobiopesticides.

  • Essential Tremor: Current Concepts and Controversies

    • 1st Edition
    • Volume 163
    • Sheng-Han Kuo + 1 more
    • English
    Tremors, Volume 163 in the International Review in Neurobiology serial highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Neurosurgical Management of Psychiatric Disorders, Part B

    • 1st Edition
    • Volume 272
    • English
    Neurosurgical Management of Psychiatric Disorders, Part B, Volume 267 in the Progress in Brain Research serial highlights new advances in the field with this new volume presenting interesting chapters on topics such as the Neurosurgical Management of Tourette Syndrome, Stereotactic Surgeries for Opioid Addiction: Patient Selection and Results, Psychiatric Disorders as Indication for Surgical Management of Drug-Resistant Temporal Epilepsy, Surgery of Autism: Is it Possible?, Psychogenic Pain: Diagnosis and Management, Stereotactic Cingulotomy and Capsulotomy for Obsessive-Compulsive Disorders: Indications and Comparative Results, and much more.

  • Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-oncology

    From Basic Research to Advanced Study
    • 1st Edition
    • Imteyaz Qamar + 1 more
    • English
    Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-Oncology: From Basic Research to Advanced Study analyzes the emerging the field of cardio-oncology, reviewing recent advancements in the field, discussing how to monitor and treat cancer survivors for cardiotoxicity, and identifying potential cardiac side effects in novel cancer therapies. By adopting a translational approach, the book first comprehensively covers the basic science, mechanisms and concepts, which is followed by advanced state-of-art of cardio-oncology. Other sections cover tyrosine kinase inhibitors, Anthracyclines, and biomarkers in cardiotoxicity induced by chemotherapeutic drugs, noninvasive cardiovascular imaging techniques, radiotherapy induced cardiovascular, and more. Anti-cancer treatment is associated with serious cardiovascular adverse events, including arterial and pulmonary hypertension, supraventricular and ventricular arrhythmias, systolic and diastolic cardiac dysfunction and coronary artery disease. Progress in cancer therapy over the past decades improved long-term survival but increased cancer therapy-related cardiotoxicity. Both traditional chemotherapeutic agents and newer therapies have demonstrated profound cardiovascular toxicities. It is important to understand the mechanisms of these toxicities to establish strategies for the prevention and management of complications—arrhyt... heart failure, and even death.

  • Redox Chemistry and Biology of Thiols

    • 1st Edition
    • Beatriz Alvarez + 3 more
    • English
    Redox Chemistry and Biology of Thiols offers an applied, comprehensive overview of redox chemistry and biology of thiol-dependent processes. Running from basic biology and chemistry of redox phenomena to research methods and highlighting recently identified roles of thiols across cellular and bodily systems, this book draws upon a range of disciplines to illuminate new research directions, new applications of thiol studies, and clinical translation. Sections cover thiol oxidizing species, thiol reactivity and modifications, thioredoxin, glutaredoxin, glutathione, peroxidases, thiol repair enzymes, thiol oxidative signaling, disulfide bond formation, thiol-based redox biosensors, cysteine and hydrogen sulfide metabolism, iron-sulfur cluster biogenesis, thiols in chloroplasts, blood thiols, sugar and polyamine thiols in pathogenic organisms, redox medicine (therapeutic applications of thiols and drug development), as well as methods and bioinformatics tools.

  • Braconidae of the Middle East (Hymenoptera)

    Taxonomy, Distribution, Biology, and Biocontrol Benefits of Parasitoid Wasps
    • 1st Edition
    • Neveen S. Gadallah + 2 more
    • English
    Braconidae of the Middle East (Hymenoptera): Taxonomy, Distribution, Biology, and Biocontrol Benefits of Parasitoid Wasps provides the latest and most comprehensive knowledge of parasitoid wasp species. The highest concentration of these species is native to, or found in, the Middle East. This book covers the distribution of these species across the Palearctic region and their widespread global benefits as natural biocontrol agents. Each chapter covers a braconid subfamily, providing introductory information on its biology and phylogeny, total number of species, global distribution, and how they can be used to control pests and invasive insect species. In addition, this book discusses the importance of integrated pest management, specifically how Braconidae can be used for one-time or repeated introduction to natural enemies in suppressing pest populations. Finally, each chapter offers an illustrative key for readers to visualize and identify each species.

  • Covid-19: Biomedical Perspectives

    • 1st Edition
    • Volume 50
    • English
    Covid-19: Biomedical Perspectives, Volume 50 in the Methods in Microbiology series highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Individual chapters in this new release include Sensitive methods for detection of SARS-CoV-2 RNA, Treatment of COVID-19 using Chinese herbal medicine, Understanding how SARS-CoV-2 is evolving and its impact on COVID-19 animal models and vaccine evaluation, Methods in machine learning to identify COVID-19 literature, COVID-19 seasonal behavior and the mutational landscape of the SARS-CoV-2 virus, CRISPR use in Diagnosis and Therapy for COVID-19, and much more.

  • Carbon Dots in Agricultural Systems

    Strategies to Enhance Plant Productivity
    • 1st Edition
    • Raju Khan + 2 more
    • English
    Carbon Dots in Agricultural Systems integrates and crystallizes the emerging knowledge and application strategies of carbon dots as a powerful tool in agriculture systems. The book includes practical insights into the synthesis of carbon dots from indigenous raw materials and how to employ them in agriculture systems to increase crop productivity and provide renewable and cost-effective strategies that meet agricultural needs. Presented by an international team of experts, this resource updates on the latest in synthesis, physical, chemical and optical properties, along with the effects and mechanisms of carbon dots, all further explained in real-world studies. Finally, the book highlights emerging innovative topics which are of great relevance to scientists, academicians and innovators in agriculture (soil science, agricultural chemistry and agronomy) and biotechnology for further research and development.

  • Sex and Gender Bias in Technology and Artificial Intelligence

    Biomedicine and Healthcare Applications
    • 1st Edition
    • Davide Cirillo + 2 more
    • English
    Sex and Gender Bias in Technology and Artificial Intelligence: Biomedicine and Healthcare Applications details the integration of sex and gender as critical factors in innovative technologies (artificial intelligence, digital medicine, natural language processing, robotics) for biomedicine and healthcare applications. By systematically reviewing existing scientific literature, a multidisciplinary group of international experts analyze diverse aspects of the complex relationship between sex and gender, health and technology, providing a perspective overview of the pressing need of an ethically-informed science. The reader is guided through the latest implementations and insights in technological areas of accelerated growth, putting forward the neglected and overlooked aspects of sex and gender in biomedical research and healthcare solutions that leverage artificial intelligence, biosensors, and personalized medicine approaches to predict and prevent disease outcomes. The reader comes away with a critical understanding of this fundamental issue for the sake of better future technologies and more effective clinical approaches.

  • Nanotheranostics for Treatment and Diagnosis of Infectious Diseases

    • 1st Edition
    • Keerti Jain + 1 more
    • English
    Nanotheranostics for Treatment and Diagnosis of Infectious Diseases comprises the latest information on the technological advancements made in the field of nanotechnology for application in therapeutics with diagnostic applications. The book focuses on the theranostic applications of nanomaterials in infectious diseases, highlighting that rapid diagnosis, safe and effective treatment and strong preventive measures like vaccines are urgently needed. It compiles all relevant information to help scientists, researchers and students understand the role of nanomaterials, how nanomaterials could be explored simultaneously for therapeutic and diagnostic applications, and how to ensure safety and efficacy of these nanomaterials. Sections cover fundamental concepts, emerging concerns and challenges to combat infectious diseases, the characterization of nanomaterials for theranostic applications, and the toxicity, biocompatibility and regulatory perspectives in the diagnosis and treatment of infectious diseases.

  • One, No One, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part B

    • 1st Edition
    • Volume 368
    • English
    One, No One, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part B, Volume 369 provides in-depth reviews on the last progresses on the role of macrophages in health and diseases, with a special focus on the role of macrophages during development. New chapters cover The role of salivary gland macrophages in infection, disease and repair, Reprogramming or replacing brain macrophages to treat neurodegenerative disease, Targeting macrophages for cancer immunotherapy, Heart Macrophages at steady-state and disease: simple bystanders or active players?, Macrophages in the liver, and Developmental programming of macrophages.

  • The Pituitary

    • 5th Edition
    • Shlomo Melmed
    • English
    The Pituitary, Fifth Edition continues the tradition of a cogent blend of basic science and clinical medicine. The comprehensive text written by expert pituitary scholars is devoted to the pathogenesis, diagnosis and treatment of pituitary disorders. The new fifth edition has been extensively revised to reflect the most recent data on new research advances in tumorigenesis and new therapeutic approaches for pituitary tumors, particularly in acromegaly and Cushing disease. Notably, new chapters devoted to the Pituitary-Immune Interface and Pituitary Radiotherapy have been included, along with a chapter on Aggressive Pituitary Adenomas developed to align with the WHOs Classification of Pituitary Tumors. Furthermore, new authors have been invited, ensuring a fresh perspective on critical issues in the field. This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders.

  • Algae-Based Biomaterials for Sustainable Development

    Biomedical, Environmental Remediation and Sustainability Assessment
    • 1st Edition
    • Huu Hao Ngo + 4 more
    • English
    Biomass, Biofuels, and Biochemicals: Algae-Based Biomaterials for Sustainable Development, Biomedical, Environmental Remediation and Sustainability Assessment, a new release in the Biomass, Biofuels, and Biochemicals series, covers algae-based biomaterials—the green and renewable material that can be produced from various micro- and macro-algae species and utilized for several applications, including biomedical healthcare and environmental remediation. The book provides assessments of the current development of algae-based biomaterials, delivering information on diverse feedstocks and technologies for biomaterial production with a perspective surrounding sustainable development. In addition, circular bioeconomy aspects are included, giving researchers a comprehensive, sustainable development view. This valuable addition to the series delivers a much-needed reference for today’s applications in biomedical and environmental remediation.

  • Principles and Practice of Ovarian Tissue Cryopreservation and Transplantation

    • 1st Edition
    • Kutluk Oktay
    • English
    Principles and Practice of Ovarian Tissue Cryopreservation and Transplantation provides methods and techniques of ovarian tissue harvesting and cryopreservation, including instructional videos. This book will benefit a wide audience, guiding infertility specialists, fellows, residents, reproductive surgeons, reproductive endocrinologists, pediatric surgeons, embryologists, infertility nurses and gynecologists. Ovarian cryopreservation and transplantation is rapidly gaining acceptance as a successful and established fertility preservation strategy in cancer patients and beyond. Unlike other fertility preservation strategies, it can be performed in children as well as adults, and can be helpful in restoring natural ovarian function and fertility, hence this is a welcomed resource on the topic.

  • Protein Kinase Inhibitors

    From Discovery to Therapeutics
    • 1st Edition
    • Md. Imtaiyaz Hassan + 1 more
    • English
    Protein Kinase Inhibitors: From Discovery to Therapeutics offers a foundational, pragmatic overview of protein kinases inhibitors and their potential role in disease modulation and treatment. Here, international experts in the field offer an integrated discussion of kinase inhibitor biology, biomarker discovery, and methods for drug design and development. After a brief overview of kinases and kinase inhibitors, subsequent chapters discuss individual kinases that are representative of the wider kinases and kinase families, including their roles in disease pathogenesis, underlying mechanisms, potential inhibitors and their modes of action for therapeutic modulation. Several potential drugs under different stages of clinical trials are discussed, including their relevance to cancer, diabetes, obesity, cardiovascular, neurological, and auto-immune and inflammatory disease, among other disorders. The book also addresses the challenges and opportunities for future kinase inhibitor development.

  • Big Data Analytics for Healthcare

    Datasets, Techniques, Life Cycles, Management, and Applications
    • 1st Edition
    • Pantea Keikhosrokiani
    • English
    Big Data Analytics and Medical Information Systems presents the valuable use of artificial intelligence and big data analytics in healthcare and medical sciences. It focuses on theories, methods and approaches in which data analytic techniques can be used to examine medical data to provide a meaningful pattern for classification, diagnosis, treatment, and prediction of diseases. The book discusses topics such as theories and concepts of the field, and how big medical data mining techniques and applications can be applied to classification, diagnosis, treatment, and prediction of diseases. In addition, it covers social, behavioral, and medical fake news analytics to prevent medical misinformation and myths. It is a valuable resource for graduate students, researchers and members of biomedical field who are interested in learning more about analytic tools to support their work.

  • Headache and Migraine in Practice

    • 1st Edition
    • Mansoureh Togha + 4 more
    • English
    Headache and Migraine in Practice provides practical and precise approaches to the headaches and facial pains commonly encountered in hospitals and clinics. The book pays specific attention to the clinical features of headaches to present treatment solutions, while also recommending ICHD3 differential diagnoses based on diagnostic criteria. Topics covered were developed by colleagues with expertise in Neurology, Nutrition, Psychiatry, Physical Medicine, and Sports Medicine, thus providing a collaborative authorship that adds interdisciplinary value. Sections cover the diagnosis and treatment of various types of headaches in children, the elderly and women during different periods of pregnancy, lactation and hormone-related stages. This book is recommended for general practitioners, internists, neurologists, headache nurse specialists, and all others who would like to contribute to better diagnoses and more effective treatment plans for patients with headaches and facial pains.

  • Neurobiology of Brain Disorders

    Biological Basis of Neurological and Psychiatric Disorders
    • 2nd Edition
    • Michael J. Zigmond + 2 more
    • English
    Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders, Second Edition provides basic scientists a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases. Topics include developmental, autoimmune, central, and peripheral neurodegeneration, infectious diseases, and diseases of higher function. Organized by individual disorder, each chapter includes coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. This volume reflects progress in the field since publication of the first edition, with fully updated chapters, and new chapters on isolation, aging, global diseases, vascular diseases, and toxic/metabolic disease. New disorder coverage includes fibromyalgia, chronic fatigue, Restless Legs Syndrome, myasthenia gravis, and more.

  • Cell Signaling Pathways in Development

    • 1st Edition
    • Volume 149
    • English
    Cell Signaling Pathways in Development, Volume 149 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Ephrin signaling, Cell signaling to the extracellular matrix, Signaling by TGF-b superfamily members, Hedgehog signaling, Parallels in signaling during development and regeneration, Hippo signaling, Wnt/PCP signaling, Signaling oscillations in presomitic mesoderm, FGFs/RTKs subcellular signaling compartments, and Signaling dynamics.

  • Functional Bakery Products: Novel Ingredients and Processing Technology for Personalized Nutrition

    • 1st Edition
    • Volume 99
    • English
    Advances in Food and Nutrition Research, Volume 99 highlights new advances in the field, with this updated volume presenting interesting chapters on a variety of topics, including Personalizing bakery products using 3D food printing, Dietary fiber in bakery products: source, processing, and function, The realm of plant proteins with focus on their application in developing new bakery products, Guiding the formulation of baked goods for the elderly population through food oral processing: challenges and opportunities, Gluten free bakery products: Ingredients and processes, Enhancing health benefits of bakery products using phytochemicals, Sugar, salt and fat reduction of bakery products, and more.

  • Coenzyme B12 Enzymes Part A

    • 1st Edition
    • Volume 668
    • English
    B12 Enzyme, Volume 667 in the Methods in Enzymology serial, highlights new advances in the field with this new volume presenting timely, interesting chapters, including Part I: B12 Biosynthesis and B12 Chaperones, Probing the preference and regioselectivity of lower ligand activation and its role in cobamide diversity, Biosynthesis of corrinoids, The human B12 trafficking chaperones: CblC, CblD and ATR, A method for the efficient adenosylation of corrinoids, Production, purification and liposome reconstitution of cobamide synthase, Extraction and Purification of Cobamides from Bacterial Cultures, Part II: The many faces of B12-dependent enzyme reactions, Methylcobalamin-depe... methionine synthase, and much more.

  • Large Animals as Models for Human Diseases

    • 1st Edition
    • Volume 189
    • Ya-Xiong Tao
    • English
    Large Animals as Models for Human Diseases, Volume 189 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of important topics, including Sheep as a model for neuroendocrinology research, Relevance of dog as a model for urologic diseases, Relevance of lactocrine hypothesis to human maternal programming of development, Comparative aspects of embryo implantation, Pig as an animal model for obesity, Canine models of cancer, Bovine model for human ovarian diseases, Mutations in G protein-coupled receptors in large animals: Modeling human diseases, and more.

  • Advanced Methods and Mathematical Modeling of Biofilms

    Applications in Health Care, Medicine, Food, Aquaculture, Environment, and Industry
    • 1st Edition
    • Mojtaba Aghajani Delavar + 1 more
    • English
    Advanced Mathematical Modelling of Biofilms and its Applications covers the concepts and fundamentals of biofilms, including sections on numerical discrete and numerical continuum models and different biofilms methods, e.g., the lattice Boltzmann method (LBM) and cellular automata (CA) and integrated LBM and individual-based model (iBM). Other sections focus on design, problem-solving and state-of-the-art modelling methods. Addressing the needs to upgrade and update information and knowledge for students, researchers and engineers on biofilms in health care, medicine, food, aquaculture and industry, this book also covers areas of uncertainty and future needs for advancing the use of biofilm models. Over the past 25-30 years, there have been rapid advances in various areas of computer technologies, applications and methods (e.g. complex programming and algorithms, lattice Boltzmann method, high resolution visualization and high-performance computation). These new and emerging technologies are providing unprecedented opportunities to develop modeling frameworks of biofilms and their applications.

  • Unraveling the Complexities of Metastasis

    Transition from a Segmented View to a Conceptual Continuum
    • 1st Edition
    • Ammad Ahmad Farooqi + 2 more
    • English
    Unraveling the Complexities of Metastasis: Transition from a Segmented View to a Conceptual Continuum provides a critical overview of the recent developments of metastasis research and how progress can be further enhanced in the field. Metastasis is a highly complicated mechanism and prognostic analysis of different metastatic patterns in advanced cancer patients is becoming increasingly problematic. It is therefore essential to take a step back and focus on the underlying mechanisms of metastasis before moving ahead for effective translation of laboratory findings to clinically effective therapeutics. This book is surely helpful in putting together missing pieces of an incomplete jig-saw puzzle of molecular cancer. The book discusses topics such as the role of TRAIL-mediated signaling, late metastasis and mechanisms underlying tumor cell dormancy, CTCs and exomes, non-coding way of metastasis, and stem cells. Additionally, it brings relevant and updated information on nanotechnology-based docetaxel and the peculiarities of cancer cell metabolism. This book is a valuable source for cancer researchers, medical doctors and several members of biomedical field who need to understand better the complex mechanism of metastasis.

  • Biochar in Agriculture for Achieving Sustainable Development Goals

    • 1st Edition
    • Daniel C.W. Tsang + 1 more
    • English
    Biochar in Agriculture for Achieving Sustainable Development Goals introduces the state-of-the-art of biochar for agricultural applications to actualize sustainable development goals and highlight current challenges and the way forward. The book focuses on scientific knowledge and biochar technologies for agricultural soil improvement and plant growth. Sections provide state-of-the-art knowledge on biochar production and characterization, focus on biochar for agricultural application and soil improvement, discuss the roles of biochar for environmental improvement in farmland to relieve water and waste management as well as climate change, highlight biochar used for boosting bioeconomy and clean energy, and discuss future prospects. This book will be important to agricultural engineers and researchers as well as those seeking to improve overall soil and environmental conditions through the use of biochar.

  • Application of Machine Learning in Agriculture

    • 1st Edition
    • Mohammad Ayoub Khan + 2 more
    • English
    Application of Machine Learning in Smart Agriculture is the first book to present a multidisciplinary look at how technology can not only improve agricultural output, but the economic efficiency of that output as well. Through a global lens, the book approaches the subject from a technical perspective, providing important knowledge and insights for effective and efficient implementation and utilization of machine learning. As artificial intelligence techniques are being used to increase yield through optimal planting, fertilizing, irrigation, and harvesting, these are only part of the complex picture which must also take into account the economic investment and its optimized return. The performance of machine learning models improves over time as the various mathematical and statistical models are proven. Presented in three parts, Application of Machine Learning in Smart Agriculture looks at the fundamentals of smart agriculture; the economics of the technology in the agricultural marketplace; and a diverse representation of the tools and techniques currently available, and in development. This book is an important resource for advanced level students and professionals working with artificial intelligence, internet of things, technology and agricultural economics.

  • Trends of Applied Microbiology for Sustainable Economy

    • 1st Edition
    • Ravindra Soni + 3 more
    • English
    Trends of Applied Microbiology for a Sustainable Economy discusses the role of modern tools and next-generation technologies in applied microbial research, including recent trends and innovation in global biofertilizers. Agriculture has seen dramatic changes since the time of its inception. Starting with the domestication of wild plants to small-scale traditional farming and then large-scale, chemical-intensive agriculture. It is at a crossroads once again, putting a huge amount of pressure on available natural resources like soil, water and biodiversity which is bound to increase with the ever-growing human population. This book helps readers understand the challenges associated with these demographic changes.

  • Biomolecular Interactions Part B

    • 1st Edition
    • Volume 169
    • English
    Biomolecular Interactions: Part A, Volume 169, the latest release in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Emerging Mechanisms of Targeted Protein Degradation by Molecular Glues, Design and use of programmable DNA Hydrogels, Oligomerization of membrane receptors: Approaches to measure in live cells, Interactions of alpha-synuclein with biomolecules, Gel-electrophoresis based method for biomolecular interaction, Recombinant centrosome expression in bacterial system, Reconstituting CCL5-CCR5 complex for structural and mechanistic analysis, Protein engineering and design in ion channel receptors, and much more.

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