Essential Neuromodulation

2nd Edition - July 7, 2022
Editors: Jeffrey Arle, Jay L. Shils
Language: English
Hardback ISBN:
9 7 8 - 0 - 1 2 - 8 1 7 0 0 0 - 7
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 1 7 0 0 1 - 4

Essential Neuromodulation, Second Edition is a concise reference covering all of the basic principles of neuromodulation in a single affordable volume for neuroscientists, reside… Read more

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Essential Neuromodulation, Second Edition is a concise reference covering all of the basic principles of neuromodulation in a single affordable volume for neuroscientists, residents, fellows, bioengineers and basic clinical practitioners. This second edition expands on developments in the field since 2011, emphasizing essential observations from all of the important clinical phases involved in any neuromodulation: targeting, intraoperative assessment, programming, complications and complication avoidance. As neuromodulation remains an exciting and rapidly advancing field, this information is critical for neurosurgeons, neurophysiologists, bioengineers and other proceduralists.

Cover image
Title page
Table of Contents
Copyright
Contributors
Introduction
Part I. The neuromodulation approach
Chapter 1. The neuromodulation approach
Introduction
History
Applications
Ethics
Cost
Part II. Regions of application
Chapter 2. Cerebral: surface
Chapter 2
Chapter 2.1. Commentary on Chapter 2: cerebral: surface
Chapter 3. Cerebral—deep
Introduction
Chapter 3.1. Commentary on Chapter 3: cerebral–deep
Chapter 4. Spinal—extradural neuromodulation
Introduction
Chapter 4.1. Commentary on Chapter 4: spinal—extradural
Chapter 5. Peripheral nerve stimulation
Introduction
Chapter 5.1. Commentary on Chapter 5: peripheral nerve stimulation
Part III. The neuromodulation therapy interface
Chapter 6. Waveforms and mechanisms in neuromodulation
Introduction
Chapter 6.1. Commentary on Chapter 6: waveforms and mechanisms in neuromodulation
Chapter 7. The electrode—principles of the neural interface and materials
Introduction
Chapter 7.1. Commentary on Chapter 7: the electrode—principles of the neural interface and materials
Chapter 8. Device materials, handling, and upgradability
Introduction
Chapter 8.1. Commentary on Chapter 8: device materials, handling, and upgradability
Chapter 9. Electronics
Introduction
Chapter 9.1. Commentary on Chapter 9: electronics
Chapter 10. Power use in neurostimulators
Overview
Chapter 10.1. Commentary on Chapter 10: power use in neurostimulators
Part IV. Placing neuromodulation in the human body
Chapter 11. Surgical techniques
Introduction
Chapter 11.1. Commentary on Chapter 11: surgical techniques
Chapter 12. Trials and their applicability
Introduction
Chapter 12.1. Commentary on Chapter 12: trials and their applicability
Chapter 13A. Intraoperative physiology techniques to inform targeting
Background
Chapter 13A.1. Commentary on Chapter 13A: intraoperative physiology techniques to inform targeting
Chapter 13. Limiting morbidity in neuromodulation
Introduction
Chapter 13.1. Commentary on Chapter 13: limiting morbidity in neuromodulation
Part V. Troubleshooting and repair
Chapter 14. Intraoperative evaluation
Introduction
Chapter 14.1. Commentary on Chapter 14: intraoperative evaluation
Chapter 15A. Troubleshooting of neuromodulatory devices: case examples
Introduction
Chapter 15A.1. Commentary on Chapter 15A: troubleshooting of neuromodulatory devices: case examples
Part VI. Postoperative management
Chapter 15. Programming—DBS programming
Introduction
Chapter 15.1. Commentary on Chapter 15: programming—DBS programming
Chapter 16. Programming—SCS
Introduction
Chapter 16.1. Comments on Chapter 16: programming—SCS
Part VII. The end user
Chapter 17. Expectations and outcomes
Deep brain stimulation for movement disorders
Epilepsy
Conclusions
Chapter 18. Paradigm shifts and the future of neuromodulation
Introduction
Paradigm shifts
Past paradigm shifts in neuromodulation: chronic opioid therapy and spinal cord stimulation for intractable pain
Past paradigm shifts in neuromodulation: spinal cord stimulation mechanism of action and SCS-induced paresthesias required for pain relief
Anticipated paradigm shifts in neuromodulation: the future of neuromodulation
Short term
Longer term
Paradigm shifts in neuromodulation
Neuromodulation for nondisease states
Neurostimulation: the way forward
Appendix
Index

Jeffrey Arle

Jeff Arle, MD, PhD, FAANS

Dr. Arle is currently the Associate Chief of Neurosurgery at Beth Israel Deaconess Medical Center in Boston, the Chief of Neurosurgery at Mt. Auburn Hospital in Cambridge, and an Associate Professor of Neurosurgery at Harvard Medical School. He received his BA in Biopsychology from Columbia University in 1986 and his MD and PhD from the University of Connecticut in 1992. His dissertation work for his doctorate in Biomedical Sciences was in computational modeling in the Cochlear Nucleus. He then went on to do a residency in neurosurgery at the University of Pennsylvania, incorporating a double fellowship in movement disorder surgery and epilepsy surgery under Drs. Patrick Kelly, Ron Alterman, and Werner Doyle, finishing in 1999.

He edited the companion text Essential Neuromodulation with Dr. Shils, the first edition published by Elsevier in 2011. He has now practiced in the field of functional neurosurgery for 17 years and is experienced in all areas of neuromodulation from deep brain stimulators to vagus nerve, spinal cord, peripheral nerve, and motor cortex stimulators, contributing frequent peer-reviewed publications and numerous chapters to the literature on many aspects of the neuromodulation field. He currently serves as an associate editor at the journals Neuromodulation and Neurosurgery, is the co-chair of the Research and Scientific Policy Committee for the International Neuromodulation Society, and is on the Board of Directors for the International Society for Intraoperative Neurophysiology. His longstanding research interests are in the area of computational modeling in the understanding and improved design of devices used in neuromodulation treatments.

Affiliations and expertise

Associate Professor of Neurosurgery, Harvard Medical School, Boston, MA, USA

Jay L. Shils

Jay L. Shils, Ph.D., D.ABNM, FASNM, FACNS is currently the director of intraoperative neurophysiological monitoring at Rush University Medical School and an Associate Professor in the department of Anesthesiology at Rush Medical Center. He received his Bachelor of Science degree in electrical engineering from Syracuse University, and both his masters and PhD in Bio-Engineering at The University of Pennsylvania using with his thesis dissertation subject – “The Bispectrum of the Human Electroencephalogram” to investigate interactions in the visual system and study EEG in epilepsy. Dr. Shils has been involved in intraoperative neuromonitoring since 1994 specializing in microelectrode neurophysiology for movement disorders. Dr. Shils is the co-editor of two neuromodulation related books which is one of his primary interests and the first edition of this book. Dr, Shils is a past president of the ASNM and the ISIN and is the founding secretary of the ISIN. Dr. Shils is the present secretary of the ASNM. Over the years Dr. Shils has presented at over 100 national and international has published on MER, DBS, neuromodulation, and intraoperative monitoring techniques.

Affiliations and expertise

Director of Intraoperative Neurophysiological Monitoring and Associate Professor in Anesthesiology, Rush University Medical Center, Chicago, IL, USA

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Essential Neuromodulation

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Jeffrey Arle

Jay L. Shils