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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Institutional Neurosis

    • 3rd Edition
    • Russell Barton
    • English
    Institutional Neurosis describes the clinical features of the disorder in mental hospitals, its differential diagnosis, etiology, treatment, and prevention. This book defines institutional neurosis as a disease characterized by apathy, lack of initiative, loss of interest in things and events not immediately personal or present, submissiveness, and sometimes no expression of feelings of resentment at harsh or unfair orders. The cause of institutional neurosis is uncertain, but it can be associated with many factors in the environment in which the patient lives. This text considers the factors associated with institutional neurosis such as loss of contact with the outside world; enforced idleness; brutality, browbeating and teasing; bossiness of staff; loss of personal friends, possessions and personal events; drugs; ward atmosphere; and loss of prospects outside the institution. This publication is a good reference for medical practitioners and students interested in the mental changes that may result from institutional life.

  • Minireviews of the Neurosciences

    Volume 13, 14, 15
    • 1st Edition
    • Bernard B. Brodie + 1 more
    • English
    Minireviews of the Neurosciences from Life Sciences discusses the regulation of tryptophan and tyrosine hydroxylase. This book also addresses the neurochemical correlations of synaptically active amino acids. This book deals first with the role of calcium in the central effects of biogenic amines; neuroendocrinology of human sleep; factors in central serotonergic synapse regulation; noradrenergic mediation of traumatic spinal cord; role of cyclic nucleotides in visual excitation; and function and organization of chromaffin vesicle. Other chapters consider the analysis of nerve growth factor, the sympathetic regulation of thyroid hormone secretion, and the mechanism if trans-synaptic enzyme induction. A study of the functions of the catecholamines and acetylcholine in endocrine regulation is presented. The final chapters examine the effects of brain monoamines in male sexual behavior and the behavior of L-dopa in Parkinson’s disease. The book can provide useful information to neurologists, students, and researchers.

  • Thalamic Networks for Relay and Modulation

    Pergamon Studies in Neuroscience
    • 1st Edition
    • Diego Minciacchi + 2 more
    • English
    Thalamic Networks for Relay and Modulation is the third in a series that springs from an idea of Giorgio Macchi who wished to establish periodical updates on thalamic research by bringing to Italy investigators who would engage in an international sharing of ideas and experiences. It reflects the renewed interest in the modulation of thalamic relay activity by intrinsic and extrinsic sources, while continuing to underscore the essential role of the thalamus as the gatekeeper of the cerebral cortex and of the pathways to perception. The papers that form the substance of this book were presented at a Symposium held at the Catholic University, Rome, Italy, in September 1992, as a Satellite to the 15th Annual Meeting of the European Neuroscience Association. The volume is organized into four parts. Part I is basically concerned with developmental and evolutionary approaches. Part II highlights relay functions of visual, motor, and somatosensory relay nuclei and relay functions of the intralaminar nuclei. Part III deals primarily with the pharmacology of thalamic neurons. Part IV emphasizes the mechanisms that underlie the functional assembly of thalamic cells into collectively acting ensembles, largely revealed in rhythmic oscillations, and on the behavioral manifestations that accompany them.

  • Neuroendocrinology

    Volume I
    • 1st Edition
    • Luciano Martini + 1 more
    • English
    Neuroendocrinology, Volume I, is the first in a two-volume treatise designed to provide a survey of all aspects of the rapidly expanding science of neuroendocrinology. Only in recent years have the relations between the nervous system and the endocrine system come under intensive scrutiny, but their interactions have already been shown to be multiple and diverse. This diversity is reflected in the range of subjects covered. There are chapters on neural control of endocrine function; the effects of hormones on the brain; brain-endocrine interrelations during various phases of development; and the comparative aspects of neuroendocrine integration. The relation of brain chemistry to endocrine function, the effect of drugs on neuroendocrine mechanisms, and the new discipline of clinical neuroendocrinology have also been considered. Not only neurophysiologists and endocrinologists, but pharmacologists, zoologists, biochemists, psychologists, and those in clinical medicine will find the treatise of interest. Parts of neuroendocrinology have been discussed in other works, but this is the first treatise in which an attempt has been made to cover all ramifications of neuroendocrinology. This book can be used both as a text for advanced students and as a reference source.

  • Cognitive Electrophysiology of Attention

    Signals of the Mind
    • 1st Edition
    • George R. Mangun
    • English
    Cognitive Electrophysiology of Attention explores the fundamental mechanisms of attention and related cognitive functions from cognitive neuroscience perspectives. Attention is an essential cognitive ability that enables humans to process and act upon relevant information while ignoring distracting information, and the capacity to focus attention is at the core of mental functioning. Understanding the neural bases of human attention remains a key challenge for neuroscientists and psychologists, and is essential for translational efforts to treat attentional deficits in a variety of neurological and psychiatric disorders. Cognitive electrophysiology is at the center of a multidisciplinary approach that involves the efforts of psychologists, neuroscientists, neuropsychologists, psychiatrists, and neurologists to identify basic brain mechanisms and develop translational approaches to improve mental health. This edited volume is authored by leading investigators in the field and discusses methods focused on electrophysiological recordings in humans, including electroencephalograp... (EEG) and event-related potential (ERP) methods, and also incorporates evidence from functional magnetic resonance imaging (fMRI). Cognitive Electrophysiology of Attention illuminates specific models about attentional mechanisms in vision, audition, multisensory integration, memory, and semantic processing in humans.

  • Global Clinical Trials for Alzheimer's Disease

    Design, Implementation, and Standardization
    • 1st Edition
    • Menghis Bairu + 1 more
    • English
    Global Clinical Trials for Alzheimer’s Disease is a handy one-stop reference for researchers and physicians planning and conducting global clinical trials in this area. This book addresses important considerations that may arise during the successful design and execution of these trials, including site selection, local regulatory issues, pharmacogenomics, ethical matters and much more. Given the saturation of traditional clinical trial markets and the worldwide progression of Alzheimer’s disease, there is a need to focus on clinical trials in emerging markets and developing countries. This book provides you with a practical approach to recognizing the opportunities and tackling the challenges that are present during the planning and execution of global clinical trials for Alzheimer’s disease.

  • Placebo and Pain

    From Bench to Bedside
    • 1st Edition
    • Luana Colloca + 2 more
    • English
    The placebo effect continues to fascinate scientists, scholars, and clinicians, resulting in an impressive amount of research, mainly in the field of pain. While recent experimental and clinical studies have unraveled salient aspects of the neurobiological substrates and clinical relevance of pain and placebo analgesia, an authoritative source remained lacking until now. By presenting and integrating a broad range of research, Placebo and Pain enhances readers’ knowledge about placebo and nocebo effects, reexamines the methodology of clinical trials, and improves the therapeutic approaches for patients suffering from pain. Review for Placebo and Pain:“This ambitious book is the first comprehensive and unified presentation of the placebo and nocebo phenomena in the area of pain. Written by the international leading experts in the field, the book provides an accurate up-to-date [work] on placebo and pain dealing with current perspectives and future challenging issues.”--Ted Kaptchuk, Associate Professor of Medicine, Harvard Medical School

  • Peripheral Nerve Disorders

    • 1st Edition
    • Volume 115
    • Gérard Said + 1 more
    • English
    Disorders of the peripheral nervous system (PNS) are the cause of prominent neurological symptoms including weakness, sensory loss, pain and autonomic dysfunction associated with deficits, morbidity and mortality. These disorders may be primary hereditary or cryptogenic neurologic disorders confined to the PNS or part of the pathology of both the central nervous system and the PNS. Most PNS disorders are secondary to other system disorders and may be responsive to treatment of the primary disease. Important advances have been obtained in several areas including molecular genetics, biochemistry, immunology, morphology and physiology that have enhanced our understanding of the causes and consequences of damage to peripheral nerve. Understanding of both these groups of PNS diseases has greatly expanded over recent years and has led to important advances of treatment both to protect and to repair damages of peripheral nerve. This volume provides an overview of the state-of-the-art of examination, diagnosis and treatment of these very diverse disorders and will be of interest to both the research and clinical neuroscience and neurology communities.

  • Mathematical Neuroscience

    • 1st Edition
    • Stanislaw Brzychczy + 1 more
    • English
    Mathematical Neuroscience is a book for mathematical biologists seeking to discover the complexities of brain dynamics in an integrative way. It is the first research monograph devoted exclusively to the theory and methods of nonlinear analysis of infinite systems based on functional analysis techniques arising in modern mathematics. Neural models that describe the spatio-temporal evolution of coarse-grained variables—such as synaptic or firing rate activity in populations of neurons —and often take the form of integro-differential equations would not normally reflect an integrative approach. This book examines the solvability of infinite systems of reaction diffusion type equations in partially ordered abstract spaces. It considers various methods and techniques of nonlinear analysis, including comparison theorems, monotone iterative techniques, a truncation method, and topological fixed point methods. Infinite systems of such equations play a crucial role in the integrative aspects of neuroscience modeling.

  • Neuroeconomics

    Decision Making and the Brain
    • 2nd Edition
    • Paul W. Glimcher
    • English
    In the years since it first published, Neuroeconomics: Decision Making and the Brain has become the standard reference and textbook in the burgeoning field of neuroeconomics. The second edition, a nearly complete revision of this landmark book, will set a new standard. This new edition features five sections designed to serve as both classroom-friendly introductions to each of the major subareas in neuroeconomics, and as advanced synopses of all that has been accomplished in the last two decades in this rapidly expanding academic discipline. The first of these sections provides useful introductions to the disciplines of microeconomics, the psychology of judgment and decision, computational neuroscience, and anthropology for scholars and students seeking interdisciplinary breadth. The second section provides an overview of how human and animal preferences are represented in the mammalian nervous systems. Chapters on risk, time preferences, social preferences, emotion, pharmacology, and common neural currencies—each written by leading experts—lay out the foundations of neuroeconomic thought. The third section contains both overview and in-depth chapters on the fundamentals of reinforcement learning, value learning, and value representation. The fourth section, “The Neural Mechanisms for Choice,” integrates what is known about the decision-making architecture into state-of-the-art models of how we make choices. The final section embeds these mechanisms in a larger social context, showing how these mechanisms function during social decision-making in both humans and animals. The book provides a historically rich exposition in each of its chapters and emphasizes both the accomplishments and the controversies in the field. A clear explanatory style and a single expository voice characterize all chapters, making core issues in economics, psychology, and neuroscience accessible to scholars from all disciplines. The volume is essential reading for anyone interested in neuroeconomics in particular or decision making in general.

  • Novel Psychoactive Substances

    Classification, Pharmacology and Toxicology
    • 1st Edition
    • Paul I. Dargan + 1 more
    • English
    Novel Psychoactive Substances: Classification, Pharmacology and Toxicology provides readers with background on the classification, detection, supply and availability of novel psychoactive substances, otherwise known as "legal highs." This book also covers individual classes of novel psychoactive substances that have recently emerged onto the recreational drug scene and provides an overview of the pharmacology of the substance followed by a discussion of the acute and chronic harm or toxicity associated with the substance. Written by international experts in the field, this multi-authored book is a valuable reference for scientists, clinicians, academics, and regulatory and law enforcement professionals.

  • Introduction to Diffusion Tensor Imaging

    And Higher Order Models
    • 1st Edition
    • Susumu Mori + 1 more
    • English
    The concepts behind diffusion tensor imaging (DTI) are commonly difficult to grasp, even for magnetic resonance physicists. To make matters worse, a many more complex higher-order methods have been proposed over the last few years to overcome the now well-known deficiencies of DTI. In Introduction to Diffusion Tensor Imaging: And Higher Order Models, these concepts are explained through extensive use of illustrations rather than equations to help readers gain a more intuitive understanding of the inner workings of these techniques. Emphasis is placed on the interpretation of DTI images and tractography results, the design of experiments, and the types of application studies that can be undertaken. Diffusion MRI is a very active field of research, and theories and techniques are constantly evolving. To make sense of this constantly shifting landscape, there is a need for a textbook that explains the concepts behind how these techniques work in a way that is easy and intuitive to understand—Introduct... to Diffusion Tensor Imaging fills this gap.

  • Medical Imaging Technology

    • 1st Edition
    • Victor I. Mikla + 1 more
    • English
    Medical Imaging Technology reveals the physical and materials principles of medical imaging and image processing, from how images are obtained to how they are used. It covers all aspects of image formation in modern imaging modalities and addresses the techniques, instrumentation, and advanced materials used in this rapidly changing field. Covering conventional and modern medical imaging techniques, this book encompasses radiography, fluoroscopy, computed tomography, magnetic resonance imaging, ultrasound, and Raman spectroscopy in medicine. In addition to the physical principles of imaging techniques, the book also familiarizes you with the equipment and procedures used in diagnostic imaging.

  • Chronic Pain and Brain Abnormalities

    • 1st Edition
    • Carl Y. Saab
    • English
    It is only natural for someone in pain to attend to the body part that hurts. Yet this book tells the story of persistent pain having negative effects on brain function. The contributors, all leading experts in their respective fields of pain electrophysiology, brain imaging, and animal models of pain, strive to synthesize compelling and, in some ways, connected hypotheses with regard to pain-related changes in the brain. Together, they contribute their clinical, academic, and theoretical expertise in a comprehensive overview that attempts to define the broader philosophical context of pain (disentangling sensical from nonsensical claims), list the changes known to take place in the brains of individuals with chronic pain and animal models of pain, address the possible causes and mechanisms underlying these changes, and detail the techniques and analytical methods at our disposal to "visualize" and study these changes.

  • Invertebrate Learning and Memory

    • 1st Edition
    • Volume 22
    • Randolf Menzel + 1 more
    • English
    Understanding how memories are induced and maintained is one of the major outstanding questions in modern neuroscience. This is difficult to address in the mammalian brain due to its enormous complexity, and invertebrates offer major advantages for learning and memory studies because of their relative simplicity. Many important discoveries made in invertebrates have been found to be generally applicable to higher organisms, and the overarching theme of the proposed will be to integrate information from different levels of neural organization to help generate a complete account of learning and memory. Edited by two leaders in the field, Invertebrate Learning and Memory will offer a current and comprehensive review, with chapters authored by experts in each topic. The volume will take a multidisciplinary approach, exploring behavioral, cellular, genetic, molecular, and computational investigations of memory. Coverage will include comparative cognition at the behavioral and mechanistic level, developments in concepts and methodologies that will underlie future advancements, and mechanistic examples from the most important vertebrate systems (nematodes, molluscs, and insects). Neuroscience researchers and graduate students with an interest in the neural control of cognitive behavior will benefit, as will as will those in the field of invertebrate learning.

  • Intelligence and Human Progress

    The Story of What was Hidden in our Genes
    • 1st Edition
    • James Flynn
    • English
    Written by James R. Flynn of the "Flynn effect" (the sustained and substantial increase in intelligence test scores across the world over many decades), Intelligence and Human Progress examines genes and human achievement in all aspects, including what genes allow and forbid in terms of personal life history, the cognitive progress of humanity, the moral progress of humanity, and the cross-fertilization of the two. This book presents a new method for weighing family influences versus genes in the cognitive abilities of individuals, and counters the arguments of those who dismiss gains in IQ as true cognitive gains. It ranges over topics including: how family can handicap those taking the SAT; new IQ thresholds for occupations that show elite occupations are within reach of the average American; what Pol Pot did to the genetic potential of Cambodia; why dysgenics (the deterioration of human genes over the generations) is important, but no menace for the foreseeable future; and what might derail human intellectual progress. Researchers in developmental and cognitive psychology, educators, and professionals involved in intelligence testing or psychometrics will benefit from the perspectives offered here. But beyond that, anyone interested in the potential of the human mind will be engaged and challenged by one of the most important contemporary thinkers on the subject.

  • Rio-Hortega's Third Contribution to the Morphological Knowledge and Functional Interpretation of the Oligodendroglia

    • 1st Edition
    • Jose R. Iglesias-Rozas + 1 more
    • English
    Pío del Rio-Hortega, one of the pioneering neuroscientists and discoverer of microglia, has been recognized as one of the most important Spanish neurohistogists of the past century. His landmark research on oligodendroglia, originally published in Spanish in 1928, has been translated into English for the first time by Dr. José R. Iglesias-Rozas and Prof. Manuel Garrosa. The book establishes definitively the concept of oligodendroglia and describes in great detail its structure, varieties, function, origin and pathology, providing a thorough review. The entire 1928 writing is presented, including the 79 excellent drawings and photographs from the original publication. To complement the original book and provide historical context, the translators have also included an introduction to the research and a biography of Pío del Rio-Hortega. This book constitutes a milestone in the history of neuroscience, biology and medicine, and it will be valuable reading for researchers and practitioners in these fields.

  • Challenging Behavior

    • 1st Edition
    • Volume 44
    • English
    International Review of Research in Developmental Disabilities is an ongoing scholarly look at research into the causes, effects, classification systems, syndromes, etc. of developmental disabilities. Contributors come from wide-ranging perspectives, including genetics, psychology, education, and other health and behavioral sciences. Volume 44 of the series offers chapters on challenging behavior.

  • The Psychology of Learning and Motivation

    • 1st Edition
    • Volume 59
    • English
    Psychology of Learning and Motivation publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Each chapter thoughtfully integrates the writings of leading contributors, who present and discuss significant bodies of research relevant to their discipline. Volume 59 includes chapters on such varied topics as pupillometric studies of face memory, self-organization of human interaction, and the role of relational competition in the comprehension of modifier-noun phrases and noun-noun compounds.

  • Cellular Migration and Formation of Neuronal Connections

    Comprehensive Developmental Neuroscience
    • 1st Edition
    • John Rubenstein + 1 more
    • English
    The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurolog... treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 2 offers 56 high level articles devoted mainly to Formation of Axons and Dendrites, Migration, Synaptogenesis, Developmental Sequences in the Maturation of Intrinsic and Synapse Driven Patterns.

  • Neural Circuit Development and Function in the Healthy and Diseased Brain

    Comprehensive Developmental Neuroscience
    • 1st Edition
    • John Rubenstein + 1 more
    • English
    The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurolog... treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 3 offers 40 high level articles devoted mainly to anatomical and functional development of neural circuits and neural systems, as well as those that address neurodevelopmental disorders in humans and experimental organisms.

  • Patterning and Cell Type Specification in the Developing CNS and PNS

    Comprehensive Developmental Neuroscience
    • 1st Edition
    • John Rubenstein + 1 more
    • English
    The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurolog... treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems.

  • Pediatric Demyelinating Disease and its Mimics, An Issue of Neuroimaging Clinics

    • 1st Edition
    • Volume 23-2
    • Manohar Shroff
    • English
    This issue reviews the state of the art in pediatric demyelinating diseases. Articles cover topics on childhood transverse myelitis, neuromyelitis optica, multiple sclerosis, acute demyelinating encephalopathy, and more.

  • Pediatric Neurology, Part I

    • 1st Edition
    • Volume 111
    • Olivier Dulac + 2 more
    • English
    The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology – not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults. Just as pediatric neurology evolved as an identified specialty as the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into so many subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertise thus is provided to some trainees through fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research. Since the infectious context, the genetic background and medical practice vary throughout the world, this diversity needs to be represented in a pediatric neurology textbook. Taken together, and although brain malformations (H. Sarnat & P. Curatolo, 2007) and oncology (W. Grisold & R. Soffietti) are covered in detail in other volumes of the same series and therefore only briefly addressed here, these considerations justify the number of volumes, and the number of authors who contributed from all over the world. Experts in the different subspecialties also contributed to design the general framework and contents of the book. Special emphasis is given to the developmental aspect, and normal development is reminded whenever needed – brain, muscle and the immune system. The course of chronic diseases into adulthood and ethical issues specific to the developing nervous system are also addressed.

  • Pediatric Neurology, Part III

    • 1st Edition
    • Volume 113
    • English
    The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology – not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults. Just as pediatric neurology evolved as an identified specialty as the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into so many subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertise thus is provided to some trainees through fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research. Since the infectious context, the genetic background and medical practice vary throughout the world, this diversity needs to be represented in a pediatric neurology textbook. Taken together, and although brain malformations (H. Sarnat & P. Curatolo, 2007) and oncology (W. Grisold & R. Soffietti) are covered in detail in other volumes of the same series and therefore only briefly addressed here, these considerations justify the number of volumes, and the number of authors who contributed from all over the world. Experts in the different subspecialties also contributed to design the general framework and contents of the book. Special emphasis is given to the developmental aspect, and normal development is reminded whenever needed – brain, muscle and the immune system. The course of chronic diseases into adulthood and ethical issues specific to the developing nervous system are also addressed.

  • Pediatric Neurology, Part II

    • 1st Edition
    • Volume 112
    • Olivier Dulac + 2 more
    • English
    The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology – not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults. Just as pediatric neurology evolved as an identified specialty as the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into so many subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertise thus is provided to some trainees through fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research. Since the infectious context, the genetic background and medical practice vary throughout the world, this diversity needs to be represented in a pediatric neurology textbook. Taken together, and although brain malformations (H. Sarnat & P. Curatolo, 2007) and oncology (W. Grisold & R. Soffietti) are covered in detail in other volumes of the same series and therefore only briefly addressed here, these considerations justify the number of volumes, and the number of authors who contributed from all over the world. Experts in the different subspecialties also contributed to design the general framework and contents of the book. Special emphasis is given to the developmental aspect, and normal development is reminded whenever needed – brain, muscle and the immune system. The course of chronic diseases into adulthood and ethical issues specific to the developing nervous system are also addressed.

  • Context Effects on Embodied Representation of Language Concepts

    • 1st Edition
    • Jie Yang
    • English
    Embodied theories claim that semantic representations are grounded in sensorimotor systems, but the contribution of sensorimotor brain areas in representing meaning is still controversial. One current debate is whether activity in sensorimotor areas during language comprehension is automatic. Numerous neuroimaging studies reveal activity in perception and action areas during semantic processing that is automatic and independent of context, but increasing findings show that involvement of sensorimotor areas and the connectivity between word-form areas and sensorimotor areas can be modulated by contextual information. Context Effects on Embodied Representation of Language Concepts focuses on these findings and discusses the influences from word, phrase, and sentential contexts that emphasize either dominant conceptual features or non-dominant conceptual features.

  • Memory Reconsolidation

    • 1st Edition
    • Cristina M. Alberini
    • English
    As little as 10 years ago, it was believed that memory went from short to long term via one consolidation practice that made that memory intractable. Since then, research has shown that long-term memories can be activated, modified, and reconsolidated in their new form. This research indicates that memories are more dynamic than once believed. And understanding how this process works and helping people to redefine established memories can be clinically useful if those memories lead to problems, as is the case in post-traumatic stress disorder. This book provides a comprehensive overview of research on memory reconsolidation; what this has to say about the formation, storage, and changeability of memory; and the potential applications of this research to treating clinical disorders.

  • The Psychology of Learning and Motivation

    • 1st Edition
    • Volume 58
    • English
    The Psychology of Learning and Motivation series publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving.

  • Decision Making: Neural and Behavioural Approaches

    • 1st Edition
    • Volume 202
    • English
    This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields.This volume explores interdisciplinary research on decision making taking a neural and behavioural approach

  • Encyclopedia of Sleep

    • 1st Edition
    • Clete Kushida
    • English
    In a world of 24-hour media saturation, sleep has become an increasingly fraught enterprise. The award-winning four-volume Encyclopedia of Sleep, Four Volume Set is the largest reference, either online or in print, on the subject of sleep. Written to be useful for the novice and the established researcher and clinician, Topic areas will include sleep across the life cycle and in other species, sleep and women, sleep and the elderly, pediatric sleep, sleep deprivation and loss, sleep mechanisms, sleep physiology and pathophysiology, sleep disorders, neurobiology, chronobiology, pharmacology, and impact of other disorders on sleep. Recognizing the many fields that are connected to sleep science, the editorial team has been carefully chosen to do justice to this highly interdisciplinary field of study. The steady growth of researchers and clinicians in the sleep field attests to the continued interest in the scientific study of sleep and the management of patients with sleep disorders, and anyone involved in this exciting field should find this work to be an invaluable reference.

  • Epigenetic Regulation in the Nervous System

    Basic Mechanisms and Clinical Impact
    • 1st Edition
    • J. David Sweatt + 3 more
    • English
    Epigenetic Regulation in the Nervous System addresses current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior, and the potential roles of these mechanisms in neurological and psychiatric disorders. This award-winning volume spans molecular epigenetics, development, cellular physiology and biochemistry, synaptic and neural plasticity, and behavioral models, and is unique in covering epigenetically based disorders of the central nervous system.Behavioral epigenetics is the study of how environmental factors alter behavior, addressing the fundamental mechanisms that shape development and individual vulnerability/resili... to adverse behavioral outcomes. By understanding the molecular mechanisms involved in epigenetic modulation, researchers may be able to develop targeted therapies for those individuals in whom it malfunctions.Edited by the most highly regarded leaders in the field, this book offers a comprehensive review of behavioral epigenetics and a balanced treatment of the strengths and weaknesses in experimentation in this area. Covering background material as well as topics of current interest, it serves both as a cutting-edge resource and a foundational reference. The book will benefit neuroscience researchers and graduate students with an interest in the links between gene regulation and behavior, as will clinicians dealing with disorders such as addiction, depression, and schizophrenia.

  • Functional Neural Transplantation III

    Primary and Stem Cell Therapies for Brain Repair, Part II
    • 1st Edition
    • Volume 201
    • English
    This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on Functional Neural Transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Head and Neck Cancer, An Issue of Neuroimaging Clinics

    • 1st Edition
    • Volume 23-1
    • Patricia A. Hudgins + 1 more
    • English
    This issue reviews the state of the art in imaging head and neck cancer. Articles cover topics on Rationale for Staging by Imaging; Oral Cavity Cancer; Oropharynx; Nasopharyngeal Carcinoma; Pitfalls in Staging Squamous Cell Carcinoma of the Hypopharynx; Larynx; Major Salivary Glands; Thyroid Cancer; Lymph Nodes; Image-Guided Tissue Sampling; and Surgical Perspective.

  • Axon Growth and Regeneration: Part 2

    • 1st Edition
    • Volume 106
    • English
    Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research. Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered. All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

  • Functional Neural Transplantation III

    Primary and Stem Cell Therapies for Brain Repair, Part I
    • 1st Edition
    • Volume 200
    • English
    This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on functional neural transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Axon Growth and Regeneration: Part 1

    • 1st Edition
    • Volume 105
    • English
    Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding Axon Growth and Regeneration.

  • Emerging Horizons in Neuromodulation

    New Frontiers in Brain and Spine Stimulation
    • 1st Edition
    • Volume 107
    • English
    This issue of International Review of Neurobiology brings together cutting-edge research on neuromodulation. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery.

  • Neurological Rehabilitation

    • 1st Edition
    • Volume 110
    • Michael P. Barnes + 1 more
    • English
    Neurological Rehabilitation is the latest volume in the definitive Handbook of Clinical Neurology series. It is the first time that this increasing important subject has been included in the series and this reflects the growing interest and quality of scientific data on topics around neural recovery and the practical applications of new research. The volume will appeal to clinicians from both neurological and rehabilitation backgrounds and contains topics of interest to all members of the multidisciplinary clinical team as well as the neuroscience community. The volume is divided into five key sections. The first is a summary of current research on neural repair, recovery and plasticity. The authors have kept the topics readable for a non-scientific audience and focused on the aspects of basic neuroscience that should be most relevant to clinical practice. The next section covers the basic principles of neurorehabilitation, including excellent chapters on learning and skill acquisition, outcome measurement and functional neuroimaging. The key clinical section comes next and includes updates and reviews on the management of the main neurological disabling physical problems, such as spasticity, pain, sexual functioning and dysphagia. Cognitive, emotional and behavioural problems are just as important and are covered in the next section, with excellent chapters, for example, on memory and management of executive dysfunction. The final part draws the sections on symptom management together by discussing the individual diseases that are most commonly seen in neurorehabilitation and providing an overview of the management of the disability associated with those disorders. The volume is a definitive review of current neurorehabilitation practice and will be valuable to a wide range of clinicians and scientists working in this rapidly developing field.

  • Bioinformatics of Behavior: Part 2

    • 1st Edition
    • Volume 104
    • English
    This issue of International Review of Neurobiology is split over 2 volumes, bringing together cutting-edge research on Bioinformatics of Behavior. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Bioinformatics of Behavior: Part 1

    • 1st Edition
    • Volume 103
    • English
    This issue of International Review of Neurobiology is split over 2 volumes, bringing together cutting-edge research on Bioinformatics of Behavior. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Cellular and Molecular Neurobiology

    • 2nd Edition
    • Constance Hammond
    • English
    This Second Edition, is the new, thoroughly revised edition of the established and well-respected authoritative text in the field. Cellular and Molecular Neurobiology is hypothesis driven and firmly based on numerous experiments performed by experts in the field. Seven new chapters (five new and two totally rewritten) complement and expand on the first edition and are written in a way that encourages students to ask questions. Additionally, new, groundbreaking research data on dendritic processing is presented in a very easy-to-understand format.

  • Mass Action in the Nervous System

    • 1st Edition
    • Bozzano G Luisa
    • English
    Mass Action in the Nervous System: Examination of the Neurophysiological Basis of Adaptive Behavior through the EEG focuses on the neural mechanisms and the behavioral significance of the electroencephalogram... with emphasis on observations made on the mammalian olfactory system. Organized into seven chapters, this book begins with a brief nonmathematical review of the concept of the neuron and the interrelations among neurons that lead to the formation of interactive masses. Some chapters follow on the linear properties of neurons and their parts; the ionic hypothesis; the nonlinear input-output relations of neurons in masses expressed in terms of amplitude-dependent coefficients in linear differential equations; and the relations between the states of activity of neurons. Subsequent chapters describe the properties resulting from feedback within neural masses; the effects of the nonlinearities in the input-output relations of neurons on the behavior of masses; and some inferences concerning the mechanisms of neural signal processing at the level of neural masses. The book is a model for an advanced text in neurophysiology, and some understanding is assumed of the elements of the fields of linear analysis, probability, statistics, theory of potential, neuroanatomy, electrophysiology, neuropharmacology, and experimental psychology.

  • The Biology and Management of Lobsters

    Physiology and Behavior
    • 1st Edition
    • English
    This two-volume work presents a summary and review of the current state of lobster biology, ecology, physiology, behavior, and management. It emphasizes the biology of clawed lobsters (Nephropidae) and spiny lobsters (Palinuridae), with attention also given to slipper lobsters (Scyllaridae) and coral lobsters (Synaxidae).The first chapter of Volume 1 provides an overview of the general aspects of lobster biology that serves as an introduction for readers of both volumes. Subsequent chapters examine the topics of growth, neurobiology, reproduction, nutrition, pathology, social behavior, and migration patterns.The chapters in Volume II consider the ecology, population dynamics, fishery biology, and aquaculture of spiny and clawed lobsters. The topics selected in both volumes represent areas of current research whose findings have not been previously synthesized into a coherent form.An important feature of these volumes is the emphasis on the interaction between biology and management and culture. Many of the contributors have done research in both applied and basic biology and can articulate both points of view. The interaction between basic and applied research is of fundamental importance in these volumes in which management aspects of the research have been integrated with the basic biology of lobsters.The Biology and Management of Lobsterswill be of interest to crustacean biologists, marine biologists and ecologists, zoologists, physiologists, animal behavior researchers, aquaculturalists, fisheries biologists and managers of fisheries, neurobiologists, pathologists, and food scientists.

  • Adenosine in the Nervous System

    • 1st Edition
    • Richard E. Stone
    • English
    This volume in a series on neuroscience provides an overview of the last 20 years of research into the biochemistry, physiology,pharmacol... and clinical therapeutic potential of adenosine and its analogues in the nervous system. Among the topics covered are adenosine transport in nervous systemtissues, adenosine production and metabolism and the electropharmacology of adenosine.

  • Foundations of Modern Auditory Theory

    • 1st Edition
    • Jerry Tobias
    • English
    Foundations of Modern Auditory Theory, Volume I is an 11-chapter text that covers the basic auditory processes. This volume deals first with the electrophysiological and conditioning data that reflect periodicity perception, the analysis of high-frequency tones, and the mechanisms and effects of auditory masking. These topics are followed by discussions on the poststimulatory auditory fatigue and adaptation; the theoretical bases necessary for an understanding of the critical band’s ubiquity; and the mechanical events in transformation process occurring in cochlea. This volume describes the anatomical structure and electrophysiological action of the cochlea and further explores ear models to study the mechanical properties of the auditory system and the basic neural transmission processes and their properties. The concluding chapters look into the distinct patterns of disorder in psychoacoustic function and the perception of musical stimuli. This book is an ideal source for teachers and students who wish to understand the mechanisms of the auditory system.

  • Learning and Memory

    A Biological View
    • 2nd Edition
    • Bozzano G Luisa
    • English
    Learning and Memory: A Biological View is a comprehensive textbook about the neurobiology of learning and memory. Topics covered range from anatomical correlates of neuronal plasticity to drugs that modulate learning and memory, along with biochemical correlates of learning and memory. The effect of aging on memory and electrophysiological analogs of memory are also discussed. Comprised of 12 chapters, this book begins with a review of historical traditions that influenced research on the biological basis of learning and memory. Experimental results indicating that the engram for a simple classically conditioned skeletal response may be in the cerebellum are also summarized. The next chapter stresses the importance of anatomical mechanisms that could mediate learning, plasticity, and memory storage in young and adult animals. Subsequent chapters focus on the influence of peripheral hormones, including opioid peptides, on learning and memory; the contribution of individual neurotransmitter systems to learning; the psychopathology of aging; and long-term potentiation. Learning in complex vertebrate systems and direct stimulation of various brain nuclei are also considered. The final chapter presents a neurobehavioral analysis of the structure of memory formation that utilizes lesions and explores human memory pathology. This monograph is intended for advanced undergraduate students, graduate students, and research workers in the field of memory.

  • Differences in Visual Perception

    The Individual Eye
    • 1st Edition
    • Jules Davidoff
    • English
    Differences in Visual Perception: The Individual Eye examines the differences in visual perception that can occur in various circumstances when observers perceive the “same” event. More specifically, the book considers the distinction between “what happens when a person looks at the world directly and when he sits with his eyes closed and thinks.” This book is organized into five chapters and begins with an overview of differences in perception that are in operation for only a short time, emphasizing the distinction between short and long-term effects and at what point “short” becomes “long.” The reader is then introduced to the development of perception, touching on topics such as the nature-nurture issue, visual acuity and visual discrimination, color-vision, space perception, and attentional processes. The ambiguity of the stimulus is also discussed, along with the perceptual theory known as “transactionalism,” how the visual world is interpreted, and the nature of the input to the visual system. The theme that runs throughout this work is the fact that the same external input does not necessarily bring about in all of us the same perception. This book will prove useful to students as well as established researchers interested in visual perception and cognition.

  • Hormones, Brain Function And Behavior

    Proceedings of a Conference on Neuroendocrinology Held at Arden House, Harriman, New York, 1956
    • 1st Edition
    • Hudson Hoagland
    • English
    Hormones, Brain Function, and Behavior brings together the proceedings of a conference on neuroendocrinology held in May 1956 in New York. The papers explore selected aspects of hormone actions in relation to brain function and behavior and cover topics ranging from the effects of steroid hormones on the nervous system to the behavioral consequences of sex hormones and thyroid hormones. Serotonin, epinephrine, and their metabolites are also discussed in relation to experimental psychiatry. This monograph is comprised of 12 chapters and begins with an assessment of steroid hormones in relation to neuropsychiatric disorders, as well as the influence of adrenocortical steroids on brain function and metabolism. Subsequent chapters focus on the genetic and psychological determinants of sexual behavior patterns; the role of serotonin in mental disorders; the effect of thyroid hormones on appetite for alcohol and alcoholic beverages in rats; and the link between thyroid hormones and mental health. The biochemistry of serotonin and its physiological implications are also examined. This text will appeal to biologists, neuropharmacologists... neuropsychiatrists, and psychologists.

  • Hormonally Induced Changes to the Mind and Brain

    • 1st Edition
    • Bozzano G Luisa
    • English
    Describing the latest findings in both clinical and laboratory research, this volume investigates the behavioral and neural affects of endocrine activity in animals and humans. Each chapter discusses the relationship between normal endocrine control of behavior and the pathological consequences that result from endocrine abnormalities. The relevance to mental health, and basic regulatory homeostatic events are balanced with a basic understanding of how hormones affect behavior and the brain. The book is written to appeal to a wide audience of readers, from the educated lay person to the seasoned M.D. and research scientist. Chapter topics include the effects of endocrine activity on homeostasis, sexual behavior, aggression, circadian rhythms, and affective disorders, in addition to discussing steroid abuse, adrenal steroid effects on the brain, and a detailed investigation on the effects of cholecystokinin and oxytocin.

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