Books in Life sciences

Bacterial Enzymes as Targets for Drug Discovery

1st Edition
November 27, 2024
Punit Kaur + 1 more
English
Paperback
9 7 8 0 4 4 3 2 2 2 2 2 1
eBook
9 7 8 0 4 4 3 2 2 2 2 1 4

Bacterial Enzymes as Targets for Drug Discovery: Meeting the Challenges of Antibiotic Resistance addresses the gap between medical microbiology, structural biology, and genomic science in the development of new antibacterial drug development. This book consolidates detailed profiling of bacterial target enzyme families for the drug discovery process and methodologies for use and validation of the potential drug targets. The contents cover the foundations of the antibiotic drug discovery process and focus on bacterial enzymes as drug targets, building across these disciplines to provide a comprehensive resource in bacterial structural biology and genomics. This is the ideal reference for antibiotic drug discovery researchers in the pharma industry and academia. Biochemists, microbiologists, and medicinal chemists will also benefit from this books’ content.

Electrocardiography of Channelopathies

1st Edition
November 27, 2024
Manlio F. Márquez-Murillo
English
Paperback
9 7 8 0 4 4 3 2 2 3 4 4 0
eBook
9 7 8 0 4 4 3 2 2 3 4 5 7

Electrocardiography of Channelopathies: A Primer for the Clinical Cardiologist introduces readers to the inherited arrhythmia syndromes that are a leading cause of sudden cardiac death. As the ECG is the cornerstone of identifying inherited arrhythmia syndromes, this cutting-edge book is a critical resource to guide cardiologists in using the technology for optimum diagnosis and treatment of their patients. It clearly delineates the differences between each syndrome to improve accuracy and health outcomes. Its easy portability belies a vast knowledge base for use by clinicians in the moment as well as by researchers in the laboratory.This book illuminates diseases such as Short and Long QT Syndromes, Andersen-Tawil Syndrome, Brugada Syndrome, Polymorphic Ventricular Tachycardia, and Early Repolarization syndrome. Electrocardiography of Channelopathies: A Primer for the Clinical Cardiologist will no doubt become a go-to reference for experienced clinicians seeking confirmation of their diagnoses, as well as those newer to the field seeking guidance in ECG interpretation.

Advances in Biomembranes and Lipid Self-Assembly

1st Edition
Volume 40
November 27, 2024
Aleš Iglič︎ + 2 more
English
Hardback
9 7 8 0 4 4 3 2 9 6 3 6 9
eBook
9 7 8 0 4 4 3 2 9 6 3 7 6

Advances in Biomembranes and Lipid Self-Assembly, Volume 40 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

Time-Resolved Methods in Structural Biology

1st Edition
Volume 709
November 27, 2024
Peter Moody + 1 more
English
Hardback
9 7 8 0 4 4 3 3 1 4 5 6 8
eBook
9 7 8 0 4 4 3 3 1 4 5 7 5

Time-Resolved Methods in Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Neuropsychiatric Complications of HIV

1st Edition
November 26, 2024
Anchal Singh
English
Paperback
9 7 8 0 1 2 8 1 8 8 5 1 4
eBook
9 7 8 0 1 2 8 1 8 8 5 2 1

Neuropsychiatric Complications of HIV: A Challenging Health Concern examines these neuropsychiatric complications prevalent in those who are HIV positive, providing clinical correlation, translational significance, and details guides to neurocognitive assessment, brain imaging, and related neuropharmacology. Written for clinicians, researchers, and students working with HIV and AIDS, the book begins with the biology of HIV, a complete look at available ARTs and antibodies, as well as diagnostics tools for HIV.It continues on to the epidemiology of NeuroAIDs and the manifestations of it—cognitive deficits, dementia, depression, agitation, psychosis, and cognitive slowing.

Capute and Accardo's Neurodevelopmental Disabilities in Infancy and Childhood

4th Edition
November 26, 2024
Fatima Y Ismail + 2 more
English
Hardback
9 7 8 0 1 2 8 2 4 0 6 0 1
eBook
9 7 8 0 3 2 3 9 8 4 3 0 0

Capute and Accardo’s Neurodevelopmental Disabilities in Infancy and Childhood, Fourth Edition provides updated foundational, theoretical, and practical knowledge on the spectrum and continuum of neurodevelopmental disabilities shaped by ongoing advances in neuroscience and related disciplines. It reviews the over-arching principles of assessment, diagnosis, and management of patients with a wide range of neurodevelopmental disabilities. Streamlined or fully rewritten chapters, including developmental screening and surveillance, neuroimaging and genetic evaluation, early intervention, principles of pharmacological treatment, principles of successful management programs, aging and transition planning, telemedicine and care in low-resource settings are included.The book's practical, expert-led approach aims to prepare future clinicians to skillfully assess and manage children with neurodevelopmental disabilities with the aid of clinical approach flowcharts to common presentations, diagnostic algorithms and clinic notes templates.

Lanthanides in Enzymology and Microbiology

1st Edition
November 26, 2024
Akio Tani + 2 more
English
Paperback
9 7 8 0 4 4 3 1 3 3 0 7 7
eBook
9 7 8 0 4 4 3 1 3 3 0 6 0

Lanthanides in Enzymology and Microbiology, a new volume in the Foundations and Frontiers in Enzymology Series, offers a detailed discussion of lanthanides and lanthanide-dependent enzyme biology. In this book, more than a dozen global experts consider lanthanide enzymology fundamentals, organismal utilization of lanthanides, distribution and diversity of lanthanide-dependent enzymes, regulation of intracellular levels of lanthanides, gene expression regulation via lanthanides, as well as likely applications of lanthanide binding proteins. Lanthanide-dependent methanol and alcohol dehydrogenase metabolism are considered in both methylotrophs and non-methylotrophs, alongside various application areas, from recovery of rare earth elements to developing lanthanide ion binding peptides and biosynthesis of terpolymers through reverse-oxidation pathways. In providing this deep context and pathways for future research, this book acts as an invaluable resource in this emerging field for researchers and students of biochemistry, biotechnology, and environmental microbiology alike.

Translational Models of Parkinson’s Disease and related Movement Disorders

1st Edition
November 26, 2024
Wael Mohamed
English
Paperback
9 7 8 0 4 4 3 1 6 1 2 8 5
eBook
9 7 8 0 4 4 3 1 6 1 2 9 2

Translational Models of Parkinson’s Disease and Related Movement Disorders focuses on cutting-edge techniques for creating and validating current Parkinson’s Disease translational experimental models. Various characteristics of these models are examined, including the prion-like properties of -synuclein, mitochondrial functions connected to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway connected to LRRK2, VPS35, and ATP13A2 using cultured cells (including patient iPS cells). This book also highlights the future possibilities of introducing new models for Parkinson’s Disease and related movements disorders, underscoring current advancements, pre-clinical and clinical developments, and future scope related to numerous models.

Gait, Balance, and Mobility Analysis

1st Edition
November 26, 2024
Samuel Stuart + 1 more
English
Paperback
9 7 8 0 4 4 3 2 1 4 8 4 4
eBook
9 7 8 0 4 4 3 2 1 4 8 3 7

Gait, Balance, and Mobility Analysis: Theoretical, Technical, and Clinical Applications provides a comprehensive overview of gait and movement analysis techniques, from traditional motion capture to modern wearable technologies. The book contains both a technical element that focuses on biomechanics and engineering concepts for gait analysis and the application of gait analysis with clinical populations. Beginning with a comprehensive background on the underlying neural control of gait and mobility in humans and physiological control of balance, the book then covers analysis methods and techniques for laboratory, clinic or remote patient assessment.It then examines how gait, mobility and balance are impacted by musculoskeletal, neurological, and cardio-respiratory conditions. Lastly, it discusses future directions and provides recommendations for future studies. Combining the expertise of engineers and clinicians, this book takes a multidisciplinary approach to show how and why gait, balance and mobility can be used to tackle important clinical questions for various conditions.

Immune Therapy for Pancreatic and Colon Cancers

1st Edition
November 26, 2024
Ganji Purnachandra Nagaraju + 2 more
English
Paperback
9 7 8 0 4 4 3 2 4 7 4 2 2
eBook
9 7 8 0 4 4 3 2 4 7 4 3 9

Immune Therapy for Pancreatic and Colon Cancer expands the knowledge on pathways, immune modulators, immune check points, and monoclonal antibodies that can lead to appropriate cancer treatment. With a strong focus on the development of immune therapies to improve the survival rates of pancreatic and colon cancer, this book also shows the latest trends in immune targeted approaches for cancer treatment. Sections describe the role of and the immune response to pancreatic and colon cancer, gives insights to past and current immunotherapies, including metabolic reprogramming, immune blockade therapy and immune modulation.This book is a valuable resource for health professionals, scientists and researchers, students, and all those who wish to broaden their knowledge of the advances in immunotherapy in pancreatic and colon cancer, inspire them and guide their design of novel experimental projects and translational studies.

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