
Advances in Clinical Chemistry
- 1st Edition, Volume 104 - August 28, 2021
- Imprint: Academic Press
- Editor: Gregory S. Makowski
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 2 4 6 2 2 - 1
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 5 1 0 6 - 0
Advances in Clinical Chemistry, Volume 104, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laborator… Read more

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Request a sales quoteAdvances in Clinical Chemistry, Volume 104, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry. It is the benchmark publication for novel analytical approaches in the clinical laboratory.
- Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science
- Authored by world renowned clinical laboratory scientists, physicians and research scientists
- Presents the international benchmark for novel analytical approaches in the clinical laboratory
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter One: Advances in point-of-care testing for cardiovascular diseases
- Abstract
- 1: Introduction
- 2: Commercial cardiac troponin assays
- 3: Biosensors
- 4: Microfluidics
- 5: Biomarkers and a template risk panel
- 6: Conclusion
- Acknowledgment
- Chapter Two: Biomarkers of high salt intake
- Abstract
- 1: Introduction
- 2: A high salt intake and blood pressure
- 3: Hypertension and organ damage
- 4: A high salt intake and organ damage
- 5: Biomarkers for the early detection of kidney injury
- 6: Conclusion
- Chapter Three: Metabolomics in Parkinson's disease
- Abstract
- 1: Parkinson's disease
- 2: Metabolomics
- 3: Metabolomics studies on PD
- Chapter Four: Histone deacetylase in neuropathology
- Abstract
- Graphical abstract
- 1: Introduction
- 2: Classification of epigenetic modifications
- 3: Regulation of histone acetylation and deacetylation: Role of HAT and HDAC
- 4: Histone deacetylase and neuronal functions
- 5: HDAC in cellular and biologic functions
- 6: HDAC in neuronal diseases and disorders
- 7: Emerging pharmacological therapies targeting HDAC in brain
- 8: Conclusion and future perspectives
- Acknowledgments
- Chapter Five: Epigenetics in kidney diseases
- Abstract
- 1: Introduction
- 2: Epigenetic mechanisms in kidney cell biology
- 3: Epigenetics in acute kidney injury (AKI)
- 4: Epigenetics in chronic kidney disease (CKD)
- 5: Epigenetic in diabetic kidney disease (DKD)
- 6: Epigenetics in renal fibrosis
- 7: Conclusion and discussion
- Acknowledgment
- Chapter Six: Cryoglobulins: Identification, classification, and novel biomarkers of mysterious proteins
- Abstract
- 1: Introduction
- 2: Definition of cryoglobulins
- 3: Molecular basis of cryoprecipitation
- 4: Pre-analytical procedures
- 5: Laboratory investigation
- 6: Biomarkers
- 7: Mixed cryoglobulinemia and B cells
- 8: Therapeutic strategies for mixed cryoglobulinemia
- 9: COVID-19-induced vasculitis: A model resembling HCV-related MC
- 10: Conclusion
- Index
- Edition: 1
- Volume: 104
- Published: August 28, 2021
- No. of pages (Hardback): 356
- No. of pages (eBook): 356
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780128246221
- eBook ISBN: 9780323851060
GM
Gregory S. Makowski
Dr Gregory S Makowski is a board-certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President Clinical Laboratory Services Hartford HealthCare in Connecticut.