The Fovea

Structure, Function, Development, and Tractional Disorders

1st Edition - August 27, 2021
Imprint: Academic Press
Authors: Andreas Bringmann, Peter Wiedemann
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 9 0 4 6 7 - 4
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 0 4 6 8 - 1

The Fovea: Structure, Function, Development, and Disease summarizes the current biological knowledge regarding the two types of the vertebrate fovea (and its main structura… Read more

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The Fovea: Structure, Function, Development, and Disease summarizes the current biological knowledge regarding the two types of the vertebrate fovea (and its main structural elements, the Müller cells). This information is then used to explain different aspects of human vision, foveal development, and macular disorders. Sections give an overview of the retinal structure and the different types of retinal glia, survey the structure and function of the primate and non-mammalian fovea types, discuss foveal development—with a focus on the human fovea, cover the roles of Müller cells and astrocytes in the pathogenesis and regeneration of various human macular disorders are described.

Using a translational approach, this reference is a valuable text for scientists, clinicians and physicians interested in the fovea. Readers will gain a new understanding of the cellular basics of the fovea, which is the most important part of the eye.

Cover image
Title page
Table of Contents
Copyright
Acknowledgments
Introduction
Abstract
Chapter 1: Introduction: Optical properties of the retina
Abstract
1.1: Light guidance through Müller cells
1.2: Retinal areas of high cell densities
1.3: The fovea: A structural solution for high-acuity vision
Chapter 2: Basic structure of the retina
Abstract
2.1: Photoreceptors
2.2: Bipolar, horizontal, and amacrine cells
2.3: Retinal ganglion cells
2.4: Retinal vasculature
Chapter 3: Retinal glia
Abstract
3.1: RPE cells
3.2: Oligodendroglia
3.3: Microglia
3.4: Macroglia: Retinal astroglia
3.5: Macroglia: Müller glia
Chapter 4: Nonmammalian fovea
Abstract
4.1: Retinal localization of the nonmammalian fovea
4.2: Shape of the nonmammalian fovea
4.3: Histological structure of the nonmammalian fovea
4.4: Cellular arrangement in the nonmammalian fovea
4.5: Photoreceptors of the nonmammalian fovea
4.6: Optical function of the nonmammalian fovea
4.7: Motion detection and depth perception by the non-mammalian fovea
Chapter 5: Primate fovea
Abstract
5.1: Structure of the primate fovea
5.2: Glio-neuronal units of the primate fovea
5.3: Optical properties of the primate fovea
Chapter 6: Comparison of the nonmammalian and primate fovea
Abstract
Chapter 7: Development of the fovea
Abstract
7.1: Cytogenesis and retinal development
7.2: Development of the rod-free zone
7.3: Development of the area centralis
7.4: Development of the retinal vascularization
7.5: Development of the primate fovea interna
7.6: Development of the primate fovea externa
7.7: Variations in human foveal development
7.8: Improper foveal development
7.9: Development of the nonmammalian fovea
Chapter 8: Tractional disorders of the human fovea
Abstract
8.1: Posterior vitreous detachment
8.2: Vitreomacular traction
8.3: Epiretinal membranes
8.4: ILM detachment
8.5: Macular pucker
8.6: Macular pseudoholes
8.7: Myopic traction maculopathy
8.8: Macular telangiectasia type 2
8.9: Partial gap in the foveola
8.10: Foveal pseudocysts
8.11: Lamellar macular holes
8.12: Sealing and regeneration of outer foveal defects
8.13: Full-thickness macular holes
8.14: Cystoid macular edema
8.15: Glial scaffold of the foveal structure
References
List of abbreviations
List of figures
Index

Andreas Bringmann

Since 1996, the research focus of Dr. Andreas Bringmann has been the Müller cell and the retina. He studied Biology (Animal Physiology) and worked in the basic sciences after the study. He was from 1990 to 2002 scientific assistant at the Department of Neurophysiology, Paul Flechsig Institute of Brain Research, Medical Faculty of the University of Leipzig (Head of the Department: Andreas Reichenbach, MD). Since 2002, he is the Head of the Research Laboratory of the Department of Ophthalmology and Eye Clinic, Medical Faculty of the University of Leipzig, Leipzig, Germany. He has published 181 peer-reviewed original papers, 30 review articles, 10 book chapters, and 2 books.

Affiliations and expertise

Head of the Research Laboratory of the Department of Ophthalmology and Eye Hospital, Medical Faculty, University of Leipzig, Leipzig, Germany

Peter Wiedemann

Dr. Peter Wiedemann is Professor of Ophthalmology at Leipzig University. He is a vitreoretinal specialist whose expertise includes complex vitreoretinal surgery and macular disorders. Dr. Wiedemann earned his medical degree at Erlangen University, Germany. He started ophthalmic research at the Doheny Eye Institute, Los Angeles, with Dr. Stephen Ryan and completed residency and fellowship in ophthalmology at Cologne University with Prof. Klaus Heimann. In his research Dr. Wiedemann studies retinal and macular disorders and Müller cells pathophysiology. He has authored over 500 peer reviewed publications in ophthalmology and is co-editor of the textbook Ryan´s Retina. He is a member of the German National Academy of Sciences Leopoldina, the German Ophthalmological Society, the American Academy of Ophthalmology and the Club Jules Gonin. He is also a Fellow of the Academia Ophthalmologica Internationalis (AOI), the European Academy of Ophthalmology, and a Board Member of the International Council of Ophthalmology (ICO).

Affiliations and expertise

Head of the Department of Ophthalmology and Eye Hospital, Medical Faculty, University of Leipzig, Leipzig, Germany

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health