
The Fovea
Structure, Function, Development, and Tractional Disorders
- 1st Edition - August 27, 2021
- Imprint: Academic Press
- Authors: Andreas Bringmann, Peter Wiedemann
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 0 4 6 7 - 4
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 0 4 6 8 - 1
The Fovea: Structure, Function, Development, and Disease summarizes the current biological knowledge regarding the two types of the vertebrate fovea (and its main structura… Read more

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Request a sales quoteThe Fovea: Structure, Function, Development, and Disease summarizes the current biological knowledge regarding the two types of the vertebrate fovea (and its main structural elements, the Müller cells). This information is then used to explain different aspects of human vision, foveal development, and macular disorders. Sections give an overview of the retinal structure and the different types of retinal glia, survey the structure and function of the primate and non-mammalian fovea types, discuss foveal development—with a focus on the human fovea, cover the roles of Müller cells and astrocytes in the pathogenesis and regeneration of various human macular disorders are described.
Using a translational approach, this reference is a valuable text for scientists, clinicians and physicians interested in the fovea. Readers will gain a new understanding of the cellular basics of the fovea, which is the most important part of the eye.
- Adopts a translational approach, summarizing the biological knowledge regarding the structure and function of the fovea, the roles of Müller cells in mediating the structural integrity, and function of the fovea
- Provides overviews of both basic types of the vertebrate fovea, countering the popular belief that there is only one type of the vertebrate fovea, the human fovea
- Thoroughly shows the mechanisms involved in the development of the fovea that explain the rapid improvement of visual acuity in newborns
- Explains pathological changes in the foveal structure and function with evaluation pointing toward possible prevention and/or cure
- Cover image
- Title page
- Table of Contents
- Copyright
- Acknowledgments
- Introduction
- Abstract
- Chapter 1: Introduction: Optical properties of the retina
- Abstract
- 1.1: Light guidance through Müller cells
- 1.2: Retinal areas of high cell densities
- 1.3: The fovea: A structural solution for high-acuity vision
- Chapter 2: Basic structure of the retina
- Abstract
- 2.1: Photoreceptors
- 2.2: Bipolar, horizontal, and amacrine cells
- 2.3: Retinal ganglion cells
- 2.4: Retinal vasculature
- Chapter 3: Retinal glia
- Abstract
- 3.1: RPE cells
- 3.2: Oligodendroglia
- 3.3: Microglia
- 3.4: Macroglia: Retinal astroglia
- 3.5: Macroglia: Müller glia
- Chapter 4: Nonmammalian fovea
- Abstract
- 4.1: Retinal localization of the nonmammalian fovea
- 4.2: Shape of the nonmammalian fovea
- 4.3: Histological structure of the nonmammalian fovea
- 4.4: Cellular arrangement in the nonmammalian fovea
- 4.5: Photoreceptors of the nonmammalian fovea
- 4.6: Optical function of the nonmammalian fovea
- 4.7: Motion detection and depth perception by the non-mammalian fovea
- Chapter 5: Primate fovea
- Abstract
- 5.1: Structure of the primate fovea
- 5.2: Glio-neuronal units of the primate fovea
- 5.3: Optical properties of the primate fovea
- Chapter 6: Comparison of the nonmammalian and primate fovea
- Abstract
- Chapter 7: Development of the fovea
- Abstract
- 7.1: Cytogenesis and retinal development
- 7.2: Development of the rod-free zone
- 7.3: Development of the area centralis
- 7.4: Development of the retinal vascularization
- 7.5: Development of the primate fovea interna
- 7.6: Development of the primate fovea externa
- 7.7: Variations in human foveal development
- 7.8: Improper foveal development
- 7.9: Development of the nonmammalian fovea
- Chapter 8: Tractional disorders of the human fovea
- Abstract
- 8.1: Posterior vitreous detachment
- 8.2: Vitreomacular traction
- 8.3: Epiretinal membranes
- 8.4: ILM detachment
- 8.5: Macular pucker
- 8.6: Macular pseudoholes
- 8.7: Myopic traction maculopathy
- 8.8: Macular telangiectasia type 2
- 8.9: Partial gap in the foveola
- 8.10: Foveal pseudocysts
- 8.11: Lamellar macular holes
- 8.12: Sealing and regeneration of outer foveal defects
- 8.13: Full-thickness macular holes
- 8.14: Cystoid macular edema
- 8.15: Glial scaffold of the foveal structure
- References
- List of abbreviations
- List of figures
- Index
- Edition: 1
- Published: August 27, 2021
- Imprint: Academic Press
- No. of pages: 290
- Language: English
- Paperback ISBN: 9780323904674
- eBook ISBN: 9780323904681
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Andreas Bringmann
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