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Books in Life sciences

  • Colorectal Neoplasia and the Colorectal Microbiome

    Dysplasia, Probiotics, and Fusobacteria
    • 1st Edition
    • Martin H. Floch
    • English
    Colorectal Neoplasia and the Microbiome: Dysplasia, Probiotics, and Fusobacteria provides foundational knowledge on the gut microbiome and evidence for an association with colorectal neoplasia. It covers the role of microbiota in causing adenomatous polyps and colorectal cancer as well as the modulatory effect of diet and probiotics. Chapters explain a foundational history of microbiology in the colon, the epidemiology of colon polyps and cancer, dysbiosis, the role of immunology and bacteria, and the diet. The book combines medical and scientific aspects to show mechanistic aspects between microbiota and hosts, clearly presenting the association between microbiota, colonic lesions and possible causal links. The book is essential reading for everyone working with human microbiota including basic scientists, physiologists of the intestine, experts in intestinal microbiota, gastroenterologists, oncologists and surgeon.
  • 3D Printing in Medicine and Surgery

    Applications in Healthcare
    • 1st Edition
    • Daniel J. Thomas + 1 more
    • English
    3D Printing in Medicine and Surgery: Applications in Healthcare is an advanced book on surgical and enhanced medical applications that can be achieved with 3D printing. It is an essential handbook for medical practitioners, giving access to a range of practical methods, while also focusing on applied knowledge. This comprehensive resource features practical experiments and processes for preparing 3D printable materials. Early chapters cover foundational knowledge and background reading, while later chapters discuss and review the current technologies used to engineer specific tissue types, experiments and methods, medical approaches and the challenges that lie ahead for future research. The book is an indispensable reference guide to the various methods used by current medical practitioners working at the forefront of 3D printing applications in medicine.
  • Insect-Borne Diseases in the 21st Century

    • 1st Edition
    • Marcello Nicoletti
    • English
    Insect-Borne Diseases in the 21st Century provides a comprehensive look at the most notorious diseases carried by insects. It offers an assessment of current and potential insect-vectored diseases as they relate to human health and agricultural and livestock production. Written by a leading expert in insect-borne diseases, it examines the history of insect-borne diseases, beginning with those that have been well-known to scientists for decades, also including recent outbreaks like Zika. The book takes into consideration environmental conditions and climate change and explores the bionetworks and system biology of potential new superorganisms, offering preventative and protective solutions. This is a must-have resource for entomology researchers and students who seek the most up-to-date information on disease-causing pathogens transmitted by insects. This book will also serve as a resource for ordinary people whose lives may be affected by such diseases.
  • Ayurvedic Perspectives in Integrative Healthcare

    Volume 8
    • 1st Edition
    • Anika Niambi Al-Shura
    • English
    Ayurveda Perspectives in Integrated Healthcare, volume eight in the Integrative Cardiovascular Chinese Medicine series, provides a clear, structured base of knowledge which compares Ayurveda with other healthcare systems to encourage acceptance of Ayurveda in the community and within patient care practices. Sections cover the Shad Darshan, body constitution, medical aspects in Ayurvedic medicine, and the connection between material and spiritual aspects and methods for balancing lifestyle for optimal health. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine with its clear, structured base to guide clinical practice and encourage new collaboration.
  • Genetics, Neurology, Behavior, and Diet in Parkinson's Disease

    The Neuroscience of Parkinson’s Disease, Volume 2
    • 1st Edition
    • Colin R. Martin + 1 more
    • English
    Genetics, Neurology, Behavior, and Diet in Parkinson's Disease: The Neuroscience of Parkinson’s Disease, Volume 2 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. It fills a much-needed gap as a "one-stop" synopsis of everything to do with the neurology and neuroscience related to Parkinson’s disease—from chemicals and cells to individuals. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field.
  • Diagnosis and Management in Parkinson's Disease

    The Neuroscience of Parkinson’s Disease, Volume 1
    • 1st Edition
    • Colin R. Martin + 1 more
    • English
    Diagnosis and Management in Parkinson's Disease: The Neuroscience of Parkinson’s, Volume 1 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. It fills a much-needed gap as a "one-stop" synopsis of everything concerning the neurology and neuroscience related to Parkinson’s disease, from chemicals and cells to individuals. The book is an invaluable resource for neuroscientists, neurologists, and anyone in the field.
  • ODE/PDE Analysis of Antibiotic/Antimicrobial Resistance

    Programming in R
    • 1st Edition
    • William E. Schiesser
    • English
    ODE/PDE Analysis of Antibiotic/Antimicro... Resistance: Programming in R presents mathematical models for antibiotic/antimicro... resistance based on ordinary and partial differential equations (ODE/PDEs). Sections cover the basic ODE model, the detailed PDE model that gives the spatiotemporal distribution of four dependent variable components, including susceptible bacteria population density, resistant bacteria population density, plasmid number, and antibiotic concentration. The computer-based implementation of the example models is presented through routines coded (programmed) in R, a quality, open-source scientific computing system that is readily available from the Internet. As such, formal mathematics is minimized and no theorems and proofs are required. The PDE analysis is based on the method of lines (MOL), an established general algorithm for PDEs that is implemented with finite differences. Routines are available from a download link so that the example models can be executed without having to first study numerical methods and computer coding. Routines can then be applied to variations and extensions of the antibiotic/antimicro... models, such as changes in the ODE/PDE parameters (constants) and the form of the model equations.
  • The Neural Control of Movement

    Model Systems and Tools to Study Locomotor Function
    • 1st Edition
    • Patrick J. Whelan + 1 more
    • English
    From speech to breathing to overt movement contractions of muscles are the only way other than sweating whereby we literally make a mark on the world. Locomotion is an essential part of this equation and exciting new developments are shedding light on the mechanisms underlying how this important behavior occurs. The Neural Control of Movement discusses these developments across a variety of species including man. The editors focus on highlighting the utility of different models from invertebrates to vertebrates. Each chapter discusses how new approaches in neuroscience are being used to dissect and control neural networks. An area of emphasis is on vertebrate motor networks and particularly the spinal cord. The spinal cord is unique because it has seen the use of genetic tools allowing the dissection of networks for over ten years. This book provides practical details on model systems, approaches, and analysis approaches related to movement control. This book is written for neuroscientists interested in movement control.
  • Genetics, Neurology, Behavior, and Diet in Dementia

    The Neuroscience of Dementia, Volume 2
    • 1st Edition
    • Colin R. Martin + 1 more
    • English
    Genetics, Neurology, Behavior, and Diet in Dementia: The Neuroscience of Dementia, Volume 2 consolidates different fields of dementia research into a single book, covering a range of subjects, including Alzheimer’s disease, Lewy body dementia, mixed dementia, vascular dementia, physical activity, risk factors, mortality, biomarkers, SPECT, CT, MRI, questionnaires, nutrition, sleep, delirium, hearing loss, agitation, aggression, delusions, anxiety, depression, hallucinations, psychosis, senile plaques, tau and amyloid-beta, neuroinflammation, and molecular biology. This foundational, comprehensive book assembles the latest understanding on all dementias and their common features in a single source. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field.
  • Diagnosis and Management in Dementia

    The Neuroscience of Dementia, Volume 1
    • 1st Edition
    • Colin R. Martin + 1 more
    • English
    Diagnosis and Management in Dementia: The Neuroscience of Dementia, Volume 1 consolidates different fields of dementia into a single book, covering a range of subjects, including Alzheimer’s disease, Lewy body dementia, mixed dementia, vascular dementia, physical activity, risk factors, mortality, biomarkers, SPECT, CT, MRI, questionnaires, nutrition, sleep, delirium, hearing loss, agitation, aggression, delusions, anxiety, depression, hallucinations, psychosis, senile plaques, tau and amyloid-beta, neuroinflammation, molecular biology, and more. With an impact on millions globally, and billions of research dollars being invested in dementia research, this book will stimulate research in the area and inform researchers.
  • Lipid Signaling and Metabolism

    • 1st Edition
    • James M. Ntambi
    • English
    Lipid Signaling and Metabolism provides foundational knowledge and methods to examine lipid metabolism and bioactive lipid signaling mediators that regulate a broad spectrum of biological processes and disease states. Here, world-renowned investigators offer a basic examination of general lipid, metabolism, intracellular lipid storage and utilization that is followed by an in-depth discussion of lipid signaling and metabolism across disease areas, including obesity, diabetes, fatty liver disease, inflammation, cancer, cardiovascular disease and mood-related disorders. Throughout, authors demonstrate how expanding our understanding of lipid mediators in metabolism and signaling enables opportunities for novel therapeutics. Emphasis is placed on bioactive lipid metabolism and research that has been impacted by new technologies and their new potential to transform precision medicine.
  • Real-World Applications in Cognitive Neuroscience

    • 1st Edition
    • Volume 253
    • English
    Real-World Applications in Cognitive Neuroscience Volume 253, the latest release in the Progress in Brain Research series, highlights new advances in the field, with this volume presenting interesting chapters on Perception and Decision Making at Sea, The Sleep-Wake Regulation in Cognition: Applications in the Real World, Decision making and the menstrual cycle in elite athletes, Decision Making under pressure in elite football, Economics and the Brain, Predictive coding: Neuroscience and art, The brain and music, Application in behavioral change, Applications of Cognitive Neuroscience to understanding Aphantasia, Applications in Inhibitory control, Applications in Vision; helping patients find their (golf) balls again, and much more.
  • Pituitary Disorders, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 49-3
    • Niki Karavitaki
    • English
    This issue of Endocrinology and Metabolism Clinics will cover Pituitary Disorders. Curated by Dr. Niki Karavitaki, this issue will explore topics in the field that are relevant for practicing clinicians. This issue is one of four selected each year by the series Consulting Editor, Adriana G. Ioachimescu. The volume will include articles on: Epidemiology of pituitary disease, Advances in the imaging of pituitary tumours, WHO 2017 classification of pituitary tumours, Cancer immunotherapy and pituitary function, Advances in the medical treatment of Cushing’s disease, Nelson’s syndrome, Update on genetics of pituitary tumours, Dopamine agonists for pituitary tumours: benefits and risks, Acromegaly: Update on management and long-term morbidities, Endoscopic surgery for pituitary tumours, Aggressive pituitary adenomas and carcinomas, Diabetes insipidus: an update, Management of hypothalamic obesity, and Pituitary Centers of Excellence.
  • Repérage précoce des signes d'appel de dys

    Un outil pour l'école maternelle : principes, analyse et préconisations
    • 1st Edition
    • Alain Moret
    • French
    Ce livre se propose de répondre aux problèmes rencontrés par les différents professionnels (de l’éducation, de la santé, de la rééducation), face aux enfants dys (ou TSLA). Il vise à associer les médecins scolaires et les professionnels de la rééducation, en lien avec les enseignants, à la conception et/ou à la diffusion d’outils du type de celui proposé dans l’ouvrage pour, non pas poser un diagnostic, mais repérer le plus tôt possible ce qui pourrait annoncer un dys et qui mériterait donc d’être surveillé, le repérage précoce d’un éventuel trouble dys étant essentiel pour une prise en charge précoce du trouble et pour une intégration réussie de l’enfant. L’ouvrage Cet ouvrage propose des éléments concrets d’observation et d’analyse pour repérer les signes d’appel des troubles dys chez les jeunes enfants. Il initie notamment à l’utilisation d’un questionnaire de repérage des troubles conçu par l’auteur et validé auprès d’enseignants spécialisés. Commenté, enrichi d’exemples et téléchargeable en ligne, il deviendra rapidement un outil indispensable qui accompagnera les professionnels de l’enfance dans leur pratique pour repérer les troubles dys, mais également pour contribuer au bon développement de chaque enfant.
  • Neurology and Pregnancy

    Neuro-Obstetric Disorders
    • 1st Edition
    • Volume 172
    • Eric A.P. Steegers + 2 more
    • English
    Neurology and Pregnancy provides a comprehensive multidisciplinary guide to best practices for research and practicing neurologists, as well as obstetricians and other specialists caring for women with an acute or chronic neurological disorder. The book encompasses preconception care, genetic counseling, pregnancy in patients with chronic neurological disorders, and acute pregnancy-related neurological complications. Postpartum care and complications, including lactation concerns, are also addressed, as well as the long-term effects of pregnancy and its complications on maternal brain health. Vol 1 summarizes the complex neurophysiological changes in pregnancy from a basic and translational science perspective. This includes neuroimaging, principles of neuro-obstetric critical care, and ethical and medicolegal concerns, describes normal fetal cerebral development and summarizes the management of the most common prenatal neurological diagnoses. Vol 2 focuses on chronic neurological conditions in pregnancy such as epilepsy, migraine, and multiple sclerosis, as well as acute neurological disorders including preeclampsia/ eclampsia, ischemic and hemorrhagic stroke, and CNS infections. Each chapter introduction includes data on epidemiology, when applicable. In discussing management, comments of safety profiles of medications preconceptionally, during pregnancy and lactation are summarized. Each chapter includes 1-2 illustrative cases.
  • Transcription Factors for Abiotic Stress Tolerance in Plants

    • 1st Edition
    • Shabir Hussain Wani
    • English
    Transcription Factors for Abiotic Stress Tolerance in Plants highlights advances in the understanding of the regulatory network that impacts plant health and production, providing important insights for improving plant resistance. Plant production worldwide is suffering serious losses due to widespread abiotic stresses increasing as a result of global climate change. Frequently more than one abiotic stress can occur at once, for example extreme temperature and osmotic stress, which increases the complexity of these environmental stresses. Modern genetic engineering technologies are one of the promising tools for development of plants with efficient yields and resilience to abiotic stresses. Hence deciphering the molecular mechanisms and identifying the abiotic stress associated genes that control plant response to abiotic stresses is a vital requirement in developing plants with increased abiotic stress resilience.Addressin... the various complexities of transcriptional regulation, this book includes chapters on cross talk and central regulation, regulatory networks, the role of DOF, WRKY and NAC transcription factors, zinc finger proteins, CRISPR/CAS9-based genome editing, C-Repeat (CRT) binding factors (CBFs)/Dehydration responsive element binding factors (DREBs) and factors impacting salt, cold and phosphorous stress levels, as well as transcriptional modulation of genes involved in nanomaterial-plant interactions.Transcr... Factors for Abiotic Stress Tolerance in Plants provides a useful reference by unravelling the transcriptional regulatory networks in plants. Researchers and advanced students will find this book a valuable reference for understanding this vital area.
  • Stem Cell Epigenetics

    • 1st Edition
    • Volume 17
    • English
    Growing evidence suggests that epigenetic mechanisms play a central role in stem cell biology and are vital for determining gene expression during cellular differentiation and governing mammalian development. In Stem Cell Epigenetics, leading international researchers examine how chromatin regulation and bona fide epigenetic mechanisms underlie stem cell renewal and differentiation. Authors also explore how the diversity of cell types, including the extent revealed by single cell omic approaches, is achieved, and how such processes may be reversed or managed via epigenetic reprogramming.Topics discussed include chromatin in pluripotency, stem cells and DNA methylation, histone modifications in stem cells and differentiation, higher-order chromatin conformation in pluripotent cells, stem cells and cancer, epigenetics and disease modeling, brain organoids from pluripotent cells, transcriptional regulation in stem cells and differentiation, non-coding RNAs in pluripotency and early differentiation, and diseases caused by epigenetic alterations in stem cells. Additionally, the book discusses the potential implementation of stem cell epigenetics in drug discovery, regenerative medicine, and disease treatment. Stem Cell Epigenetics will provide researchers and physicians with a state-of-the-art map to orient across the frontiers of this fast-evolving field.
  • Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems

    • 1st Edition
    • Kamal Dua + 5 more
    • English
    Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models. The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development.
  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 112
    • Geoffrey M. Gadd + 1 more
    • English
    Advances in Applied Microbiology, Volume 112, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas. Chapters in this new release include discussions of Microbial mercury transformation: focus on molecules and functions, Peptidoglycan Biosynthesis, Clockwork microbial worlds , Molecular engineering to improve the levels of bioproducts from agricultural and forestry waste by filamentous fungi, Multi-species Biofilms for Resource Recovery from Wastewater, Evasion of host defenses by intracellular Staphylococcus aureus, A genomic analysis on stress-responses in C. glabrata and their relevance in pathogenesis and drug resistance, and more.
  • Food Industry Wastes

    Assessment and Recuperation of Commodities
    • 2nd Edition
    • Maria R. Kosseva + 1 more
    • English
    Food Industry Wastes: Assessment and Recuperation of Commodities, Second Edition presents a multidisciplinary view of the latest scientific and economic approaches to food waste management, novel technologies and treatment, their evaluation and assessment. It evaluates and synthesizes knowledge in the areas of food waste management, processing technologies, environmental assessment, and wastewater cleaning. Containing numerous case studies, this book presents food waste valorization via emerging chemical, physical, and biological methods developed for treatment and product recovery.This new edition addresses not only recycling trends but also innovative strategies for food waste prevention. The economic assessments of food waste prevention efforts in different countries are also explored. This book illustrates the emerging environmental technologies that are suitable for the development of both sustainability of the food systems and a sustainable economy. So, this volume is a valuable resource for students and professionals including food scientists, bio/process engineers, waste managers, environmental scientists, policymakers, and food chain supervisors.
  • A Quick Guide to Metabolic Disease Testing Interpretation

    Testing for Inborn Errors of Metabolism
    • 2nd Edition
    • Patricia Jones + 2 more
    • English
    Accurate interpretation of the organic acid chromatographs obtained from the gas chromatography/mass spectrometry requires a significant amount of practice. Pattern recognition is an important factor and a skill that is gained through time and effort. A Quick Guide to Metabolic Disease Testing Interpretation, Second Edition, provides these example chromatographs demonstrating specific disease-related metabolites for the inborn error of metabolism diagnosed via this method. One or more representative chromatographs from each of the common disorders is presented, with the important compounds noted on the chromatographs. This is a must-have for laboratory and medical professionals who interpret testing for the diagnosis and monitoring of IEM.
  • The Bioarchaeology of Metabolic Bone Disease

    • 2nd Edition
    • Megan B. Brickley + 2 more
    • English
    The Bioarchaeology of Metabolic Bone Disease, Second Edition is a comprehensive source dedicated to better understanding this group of conditions that have significant consequences for health in both past and present communities on a global scale. This edition presents an updated introduction to the biology and metabolism of mineralised tissues that are fundamental to understanding the expression of the metabolic bone diseases in skeletal remains. The extensive advances in understanding of these conditions in both bioarchaeological and biomedical work are brought together for the reader. Dedicated chapters focussing on each disease emphasise the integration of up-to-date clinical background with the biological basis of disease progression to give guidance on identification. New chapters covering anaemia and approaches to recognising the co-occurrence of pathological conditions have been included, reflecting recent advances in research. Boxes highlighting significant issues, use of information from sources such as texts and nonhuman primates, and theoretical approaches are included in the text. Each chapter closes with ‘Core Concepts’ that summarise key information. The final chapter reviews current challenges in bioarchaeology and provides directions for future research. This is a must-have resource for users at all career stages interested in integrating information on the metabolic bone diseases into bioarchaeological projects.
  • Case Studies in Neuromuscular Disorders, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 38-3
    • Aziz Shaibani
    • English
    This issue of Neurologic Clinics, guest edited by Dr. Aziz Shaibani, is devoted to Case Studies in Neuromuscular Disorders. This issue is one of four selected each year by the series Consulting Editor, Dr. Randolph W. Evan. Articles in this issue include: Myotonia, Muscular Dystrophy, Spinal Muscular Atrophy, Advances in Clinical Genetics, FSHD New Diagnosis and Therapies, Congenital Myasthenic Syndrome, Diabetic Amyotrophy, ALS: Management Problems, Diagnostic and Therapeutic Challenges in Myasthenia Gravis, Scapular Winging, Small Fiber Neuropathy, Myopathies, Distal Myopathies, Inflammatory Myopathies, Muscle Cramps, Misdiagnosis of IBM, and Immune Mediated Neuropathies.
  • An Introduction to Healthcare Informatics

    Building Data-Driven Tools
    • 1st Edition
    • Peter Mccaffrey
    • English
    An Introduction to Healthcare Informatics: Building Data-Driven Tools bridges the gap between the current healthcare IT landscape and cutting edge technologies in data science, cloud infrastructure, application development and even artificial intelligence. Information technology encompasses several rapidly evolving areas, however healthcare as a field suffers from a relatively archaic technology landscape and a lack of curriculum to effectively train its millions of practitioners in the skills they need to utilize data and related tools. The book discusses topics such as data access, data analysis, big data current landscape and application architecture. Additionally, it encompasses a discussion on the future developments in the field. This book provides physicians, nurses and health scientists with the concepts and skills necessary to work with analysts and IT professionals and even perform analysis and application architecture themselves.
  • Nutritional Composition and Antioxidant Properties of Fruits and Vegetables

    • 1st Edition
    • Amit K. Jaiswal
    • English
    Nutritional Composition and Antioxidant Properties of Fruits and Vegetables provides an overview of the nutritional and anti-nutritional composition, antioxidant potential, and health benefits of a wide range of commonly consumed fruits and vegetables. The book presents a comprehensive overview on a variety of topics, including inflorescence, flowers and flower buds (broccoli, cauliflower, cabbage), bulb, stem and stalk (onion, celery, asparagus, celery), leaves (watercress, lettuce, spinach), fruit and seed (peppers, squash, tomato, eggplant, green beans), roots and tubers (red beet, carrots, radish), and fruits, such as citrus (orange, lemon, grapefruit), berries (blackberry, strawberry, lingonberry, bayberry, blueberry), melons (pumpkin, watermelon), and more. Each chapter, contributed by an international expert in the field, also discusses the factors influencing antioxidant content, such as genotype, environmental variation and agronomic conditions.
  • Metabolic and Bioenergetic Drivers of Neurodegenerative Disease: Neurodegenerative Disease Research and Commonalities with Metabolic Diseases

    • 1st Edition
    • Volume 154
    • English
    Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease summarizes recent developments in intervention trials in neurodegenerative diseases, particularly Alzheimer’s and Parkinson’s, as well as increasing evidence for the overlap between drivers of metabolic and neurodegenerative disease that impact mitochondrial function and bioenergetics, and subsequently cellular function and pathophysiology. Topics covered include Brain Glucose and Ketone Utilization in Brain Ageing and Neurodegenerative Diseases; the Mitochondrial Hypothesis: Dysfunction, Bioenergetic Defects, and the Metabolic Link to Alzheimer’s Disease; the Metabolic Impact on Neuroinflammation and Microglial Modulation in Neurodegenerative Diseases, the Impact of Circadian and Diurnal Rhythms on Cellular Metabolic Function and Neurodegenerative Diseases, and much more.
  • Neurology and Pregnancy

    Pathophysiology and Patient Care
    • 1st Edition
    • Volume 171
    • English
    Neurology and Pregnancy provides a comprehensive multidisciplinary guide to best practices for research and practicing neurologists, as well as obstetricians and other specialists caring for women with an acute or chronic neurological disorder. The book encompasses preconception care, genetic counseling, pregnancy in patients with chronic neurological disorders, and acute pregnancy-related neurological complications. Postpartum care and complications, including lactation concerns, are also addressed, as well as the long-term effects of pregnancy and its complications on maternal brain health. Vol 1 summarizes the complex neurophysiological changes in pregnancy from a basic and translational science perspective. This includes neuroimaging, principles of neuro-obstetric critical care, and ethical and medicolegal concerns, describes normal fetal cerebral development and summarizes the management of the most common prenatal neurological diagnoses. Vol 2 focuses on chronic neurological conditions in pregnancy such as epilepsy, migraine, and multiple sclerosis, as well as acute neurological disorders including preeclampsia/ eclampsia, ischemic and hemorrhagic stroke, and CNS infections. Each chapter introduction includes data on epidemiology, when applicable. In discussing management, comments of safety profiles of medications preconceptionally, during pregnancy and lactation are summarized. Each chapter includes 1-2 illustrative cases.
  • Computational Intelligence and Its Applications in Healthcare

    • 1st Edition
    • Jitendra Kumar Verma + 2 more
    • English
    Computational Intelligence and Its Applications in Healthcare presents rapidly growing applications of computational intelligence for healthcare systems, including intelligent synthetic characters, man-machine interface, menu generators, user acceptance analysis, pictures archiving, and communication systems. Computational intelligence is the study of the design of intelligent agents, which are systems that act intelligently: they do what they think are appropriate for their circumstances and goals; they're flexible to changing environments and goals; they learn from experience; and they make appropriate choices given perceptual limitations and finite computation. Computational intelligence paradigms offer many advantages in maintaining and enhancing the field of healthcare.
  • Diabetes Mellitus

    Impact on Bone, Dental and Musculoskeletal Health
    • 1st Edition
    • Meng Hee Tan
    • English
    Diabetes Mellitus: Impact on Bone, Dental and Musculoskeletal Health focuses on the under recognized and managed conditions associated with diabetes, including impacts on bone health, dental health, hand, and foot disorders, wounds, infections, and musculoskeletal disorders. A full understanding of the relationship of diabetes to skeletal disorders remains elusive and many physicians who deal with such issues are unclear about causes and management. While the macro- and microvascular complications associated with diabetes mellitus are well known, complications associated with bone, dental and musculoskeletal health are not. Endocrinologists, primary care physicians, geriatricians, podiatrists, dentists, and researchers interested in diabetes mellitus associated bone, dental and musculoskeletal disorders will find this to be a comprehensive tome on the topic.
  • Nanotechnology for Oral Drug Delivery

    From Concept to Applications
    • 1st Edition
    • João Pedro Martins + 1 more
    • English
    Nanotechnology for Oral Drug Delivery: From Concept to Applications discusses the current challenges of oral drug delivery, broadly revising the different physicochemical barriers faced by nanotechnolgy-based oral drug delivery systems, and highlighting the challenges of improving intestinal permeability and drug absorption. Oral delivery is the most widely used form of drug administration due to ease of ingestion, cost effectiveness, and versatility, by allowing for the accommodation of different types of drugs, having the highest patient compliance. In this book, a comprehensive overview of the most promising and up-to-date engineered and surface functionalized drug carrier systems, as well as opportunities for the development of novel and robust delivery platforms for oral drug administration are discussed. The relevance of controlling the physicochemical properties of the developed particle formulations, from size and shape to drug release profile are broadly reviewed. Advances in both in vitro and in vivo scenarios are discussed, focusing on the possibilities to study the biological-material interface. The industrial perspective on the production of nanotechnology-based oral drug delivery systems is also covered. Nanotechnology for Oral Drug Delivery: From Concept to Applications is essential reading for researchers, professors, advanced students and industry professionals working in the development, manufacturing and/or commercialization of nanotechnology-based systems for oral drug delivery, targeted drug delivery, controlled drug release, materials science and biomaterials, in vitro and in vivo testing of potential oral drug delivery technologies.
  • Drug Repurposing in Cancer Therapy

    Approaches and Applications
    • 1st Edition
    • Kenneth K.W. To + 1 more
    • English
    Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy. Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource.
  • Advances in Cancer Research

    • 1st Edition
    • Volume 148
    • English
    Advances in Cancer Research, Volume 148, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research.
  • Hormones and Synapse

    • 1st Edition
    • Volume 114
    • Gerald Litwack
    • English
    Hormones and Synapse, Volume 114 in the Vitamins and Hormones series, highlights advances in the field, with this new volume presenting timely topics, including how growth hormone promotes synaptogenesis, sex hormones and proteins involved in brain plasticity, corticotropin releasing factor modulates excitatory synaptic transmission, bisphenol a and memory: a role for dendritic spines, brain insulin resistance impairs hippocampal synaptic plasticity, estradiol induces synaptic rearrangements, stress and remodeling of hippocampal spine synapses, neurotrophin-3 modulates synaptic transmission, nongenomic neurosteroid modulation of hippocampal dendritic spines, neural sex steroids and hippocampal synaptic plasticity, origin of chemical synapses, neural sex steroids and hippocampal synaptic plasticity, and much more.
  • Advances in Agronomy

    • 1st Edition
    • Volume 163
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 163, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied and exemplary of the abundant subject matter addressed by this long-running serial.
  • The Human Mitochondrial Genome

    From Basic Biology to Disease
    • 1st Edition
    • Giuseppe Gasparre + 1 more
    • English
    The Human Mitochondrial Genome: From Basic Biology to Disease offers a comprehensive, up-to-date examination of human mitochondrial genomics, connecting basic research to translational medicine across a range of disease types. Here, international experts discuss the essential biology of human mitochondrial DNA (mtDNA), including its maintenance, repair, segregation, and heredity. Furthermore, mtDNA evolution and exploitation, mutations, methods, and models for functional studies of mtDNA are dealt with. Disease discussion is accompanied by approaches for treatment strategies, with disease areas discussed including cancer, neurodegenerative, age-related, mtDNA depletion, deletion, and point mutation diseases. Nucleosides supplementation, mitoTALENs, and mitoZNF nucleases are among the therapeutic approaches examined in-depth. With increasing funding for mtDNA studies, many clinicians and clinician scientists are turning their attention to mtDNA disease association. This book provides the tools and background knowledge required to perform new, impactful research in this exciting space, from distinguishing a haplogroup-defining variant or disease-related mutation to exploring emerging therapeutic pathways.
  • Alginates in Drug Delivery

    • 1st Edition
    • Amit Kumar Nayak + 1 more
    • English
    Alginates in Drug Delivery explores the vital precepts, basic and fundamental aspects of alginates in pharmaceutical sciences, biopharmacology, and in the biotechnology industry. The use of natural polymers in healthcare applications over synthetic polymers is becoming more prevalent due to natural polymers’ biocompatibility, biodegradability, economic extraction and ready availability. To fully utilize and harness the potential of alginates, this book presents a thorough understanding of the synthesis, purification, and characterization of alginates and their derivative. This book collects, in a single volume, all relevant information on alginates in health care, including recent advances in the field. This is a highly useful resource for pharmaceutical scientists, health care professionals and regulatory scientists actively involved in the pharmaceutical product and process development of natural polymer containing drug delivery, as well as postgraduate students and postdoctoral research fellows in pharmaceutical sciences.
  • Immunopathology

    • 1st Edition
    • Volume 107
    • English
    Immunopathology, Volume 107 in the Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Viral Immunopathology will cover how the immune system, innate or adaptive, is often at the root of viral pathogenesis. This is true in diverse host systems including vertebrates, plants and insects. This volume will present the latest findings in this interesting and important area of research, and will include human, plant, fish, and insect viruses. Different kingdoms have evolved very diverse immune responses to virus infection but the common theme – namely, that effects of viruses on host immune systems can condition the induction of viral disease – will unify this concept across kingdoms.
  • Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Chemical, Optical and Bioorthogonal Methods

    • 1st Edition
    • Volume 641
    • English
    Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Chemical, Optical and Bioorthogonal Methods, Volume 641 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include caged cyclopropanes with improved tetrazine ligation kinetics, an analysis of metabolically labeled inositol phosphate messengers by NMR, cell-permeant caged inositol pyrophosphates for probing β-cells, imaging phospholipase D activity with clickable alcohols via transphosphatidylati... fluorescent biorthogonal labeling of class B GPCRs in live cells, near-infrared photoactivatable nitric oxide donors with integrated photoacoustic monitoring, and much more.
  • Our Wired Nerves

    The Human Nerve Connectome
    • 1st Edition
    • Douglas W Zochodne
    • English
    The nervous system is a complex, sophisticated system that regulates and coordinates body activities. It is made up of two major divisions: the central nervous system consisting of the brain and spinal cord and the peripheral nervous system. This consists of all other neural elements, including the peripheral nerves and the autonomic nerves. Peripheral nerves are the essential connections between the brain and spinal cord and the body. Without nerves there is no movement or sensation. Our Wired Nerves: The Human Nerve Connectome, reviews the essential anatomy and physiology of the peripheral nerve. It introduces the reader to what neuropathies are, how pain arises from damaged nerves and how nerves might be regenerated, including new and exciting ideas over how to coax their regrowth. Written by Dr. Douglas Zochodne leading expert in the field, and first book to focus on the Peripheral nerves it will surely be an essential reference for researchers and clinicians alike.
  • Autism

    • 1st Edition
    • Volume 173
    • English
    Autism, Volume 173 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. Chapters in this new release include updates on atypical brain development in autism spectrum disorder, predicting early diagnosis of autism spectrum disorder using neural and behavioral measures, the roles of the endocannabinoid system in autism spectrum disorder, the neurobiology of sensory processing in autism spectrum disorder, the effects of oxytocin administration on individuals with ASD, resting-state abnormalities of posterior cingulate in autism spectrum disorder, and more.
  • Mechanisms of Action in Disease and Recovery in Integrative Cardiovascular Chinese Medicine

    Volume 6
    • 1st Edition
    • Anika Niambi Al-Shura
    • English
    Mechanisms of Action in Disease and Recovery in Integrative Cardiovascular Chinese Medicine, volume six in the Integrative Cardiovascular Chinese Medicine series, presents the structure, function and pathology of the cardiovascular system from Traditional Chinese and Western Medicine perspectives. Sections discuss cardiac acu-anatomy, including cardiac cells and heart structure, gastrointestinal cells and mouth, esophagus, stomach, small and large intestine structures, and more, while other chapters cover the qi, yin and yang roles in cardiac rhythm and pumping actions and the pathology of the heart and vascular system and the zang and fu relationship with other body organs. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine with its clear, structured base that will guide clinical practice and encourage collaboration between Chinese and Western medicine practitioners.
  • Fighting the Opioid Epidemic

    The Role of Providers and the Clinical Laboratory in Understanding Who is Vulnerable
    • 1st Edition
    • Amitava Dasgupta
    • English
    Fighting the Opioid Epidemic: The Role of Providers and the Clinical Laboratory in Understanding Who Is Vulnerable covers the important aspects that are essential in fighting the opioid epidemic. This succinct reference highlights how the toxicology laboratory can play a vital role in fighting the opioid epidemic by implementing a robust system for drugs of abuse testing as well as drug testing in pain management patients. It targets health care professionals in a technical manner, discussing polymorphisms of important genes that may be associated with increased vulnerability of alcohol and drug addiction to an individual.
  • Cold Pressed Oils

    Green Technology, Bioactive Compounds, Functionality, and Applications
    • 1st Edition
    • Mohamed Fawzy Ramadan
    • English
    Cold Pressed Oils: Green Technology, Bioactive Compounds, Functionality, and Applications creates a multidisciplinary forum of discussion on recent advances in chemistry and the functionality of bioactive phytochemicals in lipids found in cold pressed oils. Chapters explore different cold pressed oil, focusing on cold press extraction and processing, composition, physicochemical characteristics, organoleptic attributes, nutritional quality, oxidative stability, food applications, and functional and health-promoting traits. Edited by a team of experts, the book brings a diversity of developments in food science to scientists, chemists, nutritionists, and students in nutrition, lipids chemistry and technology, agricultural science, pharmaceuticals, cosmetics, nutraceuticals and many other fields.
  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 93
    • Fidel Toldra
    • English
    Advances in Food and Nutrition Research, Volume 93, provides information on nutrients in foods and how to avoid their deficiency, especially for those essential nutrients that should be present in the diet. Specific topics covered in this new release include drying, a relevant unit operation in the manufacture of foods and nutritional products, polycyclic aromatic hydrocarbons in edible oils and fatty foods, including occurrence, formation, analysis, change, and control, food allergens and their characterization, molecular properties and clinical implications, the design, quality, safety and efficacy of extensively hydrolyzed formula for the management of cow’s milk protein allergy, and much more. The series provides the latest advances on the identification and characterization of emerging bioactive compounds with putative health benefits, as well as up-to-date information on food science, including raw materials, production, processing, distribution and consumption.
  • Obesity Hypoventilation Syndrome

    From Physiologic Principles to Clinical Practice
    • 1st Edition
    • Aiman Tulaimat
    • English
    Obesity Hypoventilation Syndrome: From Physiologic Principles to Clinical Practice summarizes the current state of knowledge regarding the epidemiology, physiology and treatment of obesity hypoventilation syndrome (OHS). Currently, the identification and management of OHS is suboptimal, especially in the acute setting, hence the misdiagnosis or mislabeling of the problem has a significant impact on patient outcomes. This volume brings together all aspects of assessment and management into a main resource for understanding the complex physiological and clinical consequences of this condition.
  • Sperling Pediatric Endocrinology

    • 5th Edition
    • Mark A. Sperling
    • English
    An ideal resource for both pediatricians and endocrinologists, Sperling’s Pediatric Endocrinology, 5th Edition, brings you fully up to date with accelerating research; new discoveries in metabolic, biochemical and molecular mechanisms; and the resulting advances in today’s clinical care. The editorial team of world-renowned pediatric endocrinologists led by Dr. Mark Sperling, as well as expert contributing authors, cover comprehensive and current aspects of both basic science and clinical practice. Whether you’re preparing for certification or have extensive clinical experience, this detailed, authoritative reference helps you increase your knowledge and determine the best possible course for every patient.
  • Neural Regenerative Nanomedicine

    • 1st Edition
    • Mehdi Razavi
    • English
    Neural Regenerative Nanomedicine presents novel, significant, experimental results relating to nanoscience and nanotechnology in neural regeneration. As current research is at the forefront of healing the nervous system, the content in the book focuses on basic, translational and clinical research in neural repair and regeneration. Chapters focus on stem cell biology to advance medical therapies for devastating disorders, the complex, delicate structures that make up the nervous system, and neurodegenerative diseases that cause progressive deterioration, including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), multiple sclerosis and multiple system atrophy.
  • Present Knowledge in Nutrition

    Basic Nutrition and Metabolism
    • 11th Edition
    • Bernadette P. Marriott + 3 more
    • English
    Present Knowledge in Nutrition: Basic Nutrition and Metabolism, Eleventh Edition, provides an accessible, referenced source on the most current information in the broad field of nutrition. Now broken into two volumes and updated to reflect scientific advancements since the publication of the last edition, the book includes expanded coverage on basic nutrition, metabolism and clinical and applied topics. This volume provides coverage of macronutrients, vitamins, minerals and other dietary components and concludes with new approaches in nutrition science that apply to many, if not all, of the nutrients and dietary components presented throughout the reference. Advanced undergraduate, graduate and postgraduate students in nutrition, public health, medicine and related fields will find this resource useful. In addition, professionals in academia and medicine, including clinicians, dietitians, physicians, health professionals, academics and industrial and government researchers will find the content extremely useful. The book was produced in cooperation with the International Life Sciences Institute (https://ilsi.org/).
  • Present Knowledge in Nutrition

    Clinical and Applied Topics in Nutrition
    • 11th Edition
    • Bernadette P. Marriott + 3 more
    • English
    Present Knowledge in Nutrition, Eleventh Edition, provides an accessible, highly readable, referenced, source of the most current, reliable, and comprehensive information in the broad field of nutrition. Now broken into two, separate volumes, and updated to reflect scientific advancements since the publication of its tenth edition, Present Knowledge in Nutrition, Eleventh Edition includes expanded coverage on the topics of basic nutrition and metabolism and clinical and applied topics in nutrition. This volume, Present Knowledge in Nutrition: Clinical and Applied Topics in Nutrition, addresses life stage nutrition and maintaining health, nutrition monitoring, measurement, and regulation, and important topics in clinical nutrition. Authored by an international group of subject-matter experts, with the guidance of four editors with complementary areas of expertise, Present Knowledge in Nutrition, Eleventh Edition will continue to be a go-to resource for advanced undergraduate, graduate and postgraduate students in nutrition, public health, medicine, and related fields; professionals in academia and medicine, including clinicians, dietitians, physicians, and other health professionals; and academic, industrial and government researchers, including those in nutrition and public health. The book was produced in cooperation with the International Life Sciences Institute (https://ilsi.org/).
  • Extrusion Cooking

    Cereal Grains Processing
    • 2nd Edition
    • Girish M. Ganjyal
    • English
    Extrusion Cooking provides a detailed description of extrusion processing with an in-depth exploration of cereal grains processing. In particular, the book addresses the basic principles of extrusion processing, various extruder parts and their design principles, food ingredients and their characteristics as they relate to extrusion. It also discusses physicochemical changes in the different ingredient components as they are processed in an extruder, modeling and control of extrusion process, scale-up aspects, extrusion plant design, food safety in extrusion, new advancements in extrusion, and a look into the future of extrusion. This valuable text serves as a one-volume reference on extrusion processing for food industry professionals and students.