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Advances in Immunology
1st Edition - September 25, 2020
Editor: Frederick W. Alt
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Advances in Immunology, Volume 147, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in… Read more
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Advances in Immunology, Volume 147, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Chapters in this new release include Histone deacetylases as targets in autoimmune and autoinflammatory diseases, The advancing area of the mechanisms involved in the evolution of HIV-1 neutralizing antibodies, T cells in latent viral infections, Communications of dendritic cells with T cells and NK cells in cancerous tissues, Mechanism and Regulation of Class Switch Recombination by IgH transcriptional Control Elements, IL-2 partial agonist, Preserving Immune Homeostasis with A20, The design of vaccine strategies to elicit HIV-1 broadly neutralizing antibodies.
Presents current developments and comprehensive reviews in immunology
Provides the latest in a longstanding, respected serial on the subject matter
Focuses on recent advances in the advancing area of the mechanisms involved in the evolution of HIV-1 neutralizing antibodies
Immunologists and infectious disease specialists, cell biologists and hematologists
1. Histone deacetylases as targets in autoimmune and autoinflammatory diseases Wilfried Ellmeier
2. Communications of dendritic cells with T cells and NK cells in cancerous tissues Jan Böttcher
3. Mechanism and Regulation of Class Switch Recombination by IgH transcriptional Control Elements Amine Khamlichi
No. of pages: 146
Published: September 25, 2020
Imprint: Academic Press
Hardback ISBN: 9780128207567
eBook ISBN: 9780128207413
Frederick W. Alt
Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.
Affiliations and expertise
Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA