ROBOTICS & AUTOMATION
Empowering Progress
Up to 25% off Essentials Robotics and Automation titles
The Stem Cell Niche during Ageing
- 1st Edition, Volume 4 - August 22, 2020
- Editor: Susie Nilsson
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 2 0 1 9 - 1
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 2 0 2 0 - 7
Advances in Stem Cells and Their Niches addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments in the field… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteAdvances in Stem Cells and Their Niches addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments in the field, including new data on disease and clinical applications. Video content illustrates such areas as protocols, transplantation techniques, and work with mice.
- Explores not only reviews of research, but also shares methods, protocols, and transplantation techniques
- Contains video content to illustrate such areas as protocols, transplantation techniques, and work with mice
- Each volume concentrates on one organ, making this a unique publication
Academic Researchers, Research scientists and graduate students in universities, industry and government
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Chapter One: The aging hematopoietic stem cell niche
- Abstract
- 1: Introduction
- 2: Cellular components of the aged HSC niche
- 3: Extracellular components of the aged HSC niche
- 4: Other factors involved in the aged HSC phenotype
- 5: The human context
- 6: Summary
- Acknowledgments
- Conflicts of interest
- Chapter Two: Aging of intestinal stem cells and associated niche
- Abstract
- 1: Introduction
- 2: Intestinal stem cells and their associated niche
- 3: Age-related alterations in the intestine
- 4: Strategies for restoring youthful function of aged intestinal stem cells
- 5: Conclusions
- Chapter Three: The aging spermatogonial stem cell niche
- Abstract
- 1: Introduction
- 2: Spermatogonial stem cell niche
- 3: Aging of the spermatogonial stem cell niche
- 4: Conclusions
- Chapter Four: The aging epidermal skin niche
- Abstract
- 1: Introduction
- 2: Morphological organization of skin into discrete compartments
- 3: Gross morphological changes in the epidermis and dermis that affect skin renewal with aging
- 4: Epidermal dependency on microenvironmental signals from the dermis
- 5: Intrinsic regulation of skin renewal: Epidermal stem and progenitor cell contributions
- 6: Extrinsic regulation of skin renewal: Dermal mesenchymal contributions
- 7: Conclusions
- Chapter Five: Aging of the ventricular-subventricular zone neural stem cell niche
- Abstract
- 1: The ventricular-subventricular zone (V-SVZ): A neurogenic and gliogenic niche in the adult mammalian brain
- 2: The NSC lineage in the adult V-SVZ
- 3: Niche cells of the adult V-SVZ
- 4: The effect of aging on the V-SVZ
- 5: Concluding remarks
- Acknowledgments
- Chapter Six: Hepatic regeneration in aging: Cell type plasticity and redundancies
- Abstract
- 1: Liver function in health and aging
- 2: Physiological consequences of liver aging
- 3: Liver cells and their progenitors in aging and disease
- 4: Mechanisms for declining liver regeneration during biological aging
- 5: Strategies to restore liver function and regenerative potential during aging
- 6: Conclusions
- Funding
- Conflicts of interest
- Chapter Seven: Mammary stem cells and their niche during aging
- Abstract
- 1: Introduction
- 2: Aging mammary stem cells at rest in quiescence
- 3: Senescence and the aging mammary gland
- 4: Mammary epithelial alterations in aging
- 5: Transcriptomic alterations in aging
- 6: Conclusion
- Chapter Eight: The cardiac stem cell niche during aging
- Abstract
- 1: Introduction
- 2: Cardiac stem cell niches during embryonic development and maturation of the heart
- 3: Cardiomyocyte turnover in the heart
- 4: The extracellular matrix (ECM) in the developing, adult and aging heart
- 5: Conclusion
- No. of pages: 258
- Language: English
- Edition: 1
- Volume: 4
- Published: August 22, 2020
- Imprint: Academic Press
- Paperback ISBN: 9780128220191
- eBook ISBN: 9780128220207
SN
Susie Nilsson
Dr Nilsson is currently involved in multiple research projects, all aimed to conduct extensive cellular, molecular and functional analyses of blood stem cells, their progeny and their bone marrow microenvironment.
Affiliations and expertise
Biomedical Manufacturing, CSIRO; Monash University, AustraliaRead The Stem Cell Niche during Ageing on ScienceDirect